Hypothermia Stimulates Glioma Stem Spheres to Spontaneously Dedifferentiate Adjacent Non-stem Glioma Cells

Cellular and Molecular Neurobiology

Volumn 35, Issue 2, 2015, Pages 217-230

  Shi, Lei ^a   Fei, Xifeng ^b   Sun, Guan ^c   Wang, Zhimin ^b   Wan, Yi ^b   Zeng, Yanjun ^d   Guo, Jun ^c  

^a KUNSHAN FIRST PEOPLE S HOSPITAL AFFILIATED TO JIANGSU UNIVERSITY   (China)

^b Suzhou Kowloon Hospital Affiliated with Shanghai Jiao Tong University School of Medicine   (China)

^c NANTONG UNIVERSITY   (China)

^d BEIJING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Glioma; Hypothermia; Stem cells

Indexed keywords

CD133 ANTIGEN; CYTOKINE; CYTOKINE ANTIBODY; MESSENGER RNA; MICRORNA; NESTIN;

ARTICLE; CANCER STEM CELL; CELL DEDIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; DNA MICROARRAY; EMBRYONIC STEM CELL; GENE EXPRESSION; GENETIC DIFFERENCE; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LOW TEMPERATURE; MICROARRAY KIT; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION SYSTEM; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR MICROENVIRONMENT; BRAIN TUMOR; CELL PROLIFERATION; CELL SEPARATION; CELL TRACKING; COLD; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; INDUCED HYPOTHERMIA; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

BRAIN NEOPLASMS; CELL DEDIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SEPARATION; CELL TRACKING; COLD TEMPERATURE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; HYPOTHERMIA, INDUCED; MICRORNAS; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; SPHEROIDS, CELLULAR;

EID: 84923638898     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-014-0114-1     Document Type: Article

References (31)

1. Barroca V, Lassalle B, Coureuil M, Louis JP, Le Page F, Testart J, Allemand I, Riou L, Fouchet P (2009) Mouse differentiating spermatogonia can generate germinal stem cells in vivo. Nat Cell Biol 11(2):190–196
2. Belinsky GS, Antic SD (2013) Mild hypothermia inhibits differentiation of human embryonic and induce pluripotent stem cells. Biotechniques 55(2):79–82
3. Cao Y, Lathia JD, Eyler CE, Wu Q, Li Z, Wang H, McLendon RE, Hjelmeland AB, Rich JN (2010) Erythropoietin receptor signaling through stat3 is required for glioma stem cell maintenance. Genes & Cancer 1:50–61
4. Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA (2011) Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. PNAS 108:7950–7955
5. Golding SE, Rosenberg E, Khalil A, McEwen A, Holmes M, Neill S, Povirk LF, Valerie K (2004) Double Strand Break Repair by Homologous Recombination Is Regulated by Cell Cycle-independent Signaling via ATM in Human Glioma Cells. J Biol Chem 279:15402–15410
6. Iliopoulos D, Hirsch HA, Wang G, Struhl K (2011) Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. PNAS 108:1397–1402
7. Jung IH, Leem GL, Jung DE, Kim MH, Kim EY, Kim SH, Park HC, Park SW (2013) Glioma is formed by active Akt1 alone and promoted by active Rac1 in transgenic zebrafish. Neuro Oncology 15:290–304
8. Kang SK, Park JB, Cha SH (2006) Multipotent, dedifferentiated cancer stem-like cells from brain gliomas. Stem Cells Dev 15(3):423–425
9. Kefas B, Comeau L, Erdle N, Montgomery E, Amos S, Purow B (2010) Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells. Neuro Oncology 12:1102–1112
10. Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A (2007) Tumor Growth Need Not Be Driven by Rare Cancer Stem Cells. Science 317:337
11. Li A, Dubey S, Varney ML, Dave BJ, Singh RK (2003) IL-8 Directly Enhanced Endothelial Cell Survival, Proliferation, and Matrix Metalloproteinases Production and Regulated Angiogenesis. J Immunol 170:3369–3376
12. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C(T)) Method. Methods 25:402–408
13. Lottaz C, Beier D, Meyer K, Kumar P, Hermann A, Schwarz J, Junker M, Oefner PJ, Bogdahn U, Wischhusen J, Spang R, Storch A, Beier CP (2010) Transcriptional Profiles of CD133 + and CD133- Glioblastoma-Derived Cancer Stem Cell Lines Suggest Different Cells of Origin. Cancer Res 70:2030–2040
14. Malla RR, Gopinath S, Gondi CS, Alapati K, Dinh DH, Tsung AJ, Rao JS (2012) uPAR and cathepsin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bcl-2 in glioma. J Neurooncol 107(1):69–80
15. Marzook H, Li DQ, Nair VS, Mudvari P, Reddy SD, Pakala SB, Santhoshkumar TR, Pillai MR, Kumar R (2012) Metastasis-associated Protein 1 Drives Tumor Cell Migration and Invasion through Transcriptional Repression of RING Finger Protein 144A. J Biol Chem 287:5615–5626
16. Nakano I, Saya H (2010) Cancer stem cells in malignant glioma-the mechanism of cancer initiation and the therapeutic development. No Shinkei Geka 38(10):879–889
17. Pek JW, Lim AK, Kai T (2009) Drosophila maelstrom ensures proper germline stem cell lineage differentiation by repressing microRNA-7. Dev Cell 17:417–424
18. Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P, Weissman IL, Clarke MF, Ailles LE (2007) Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA 104:973–978
19. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB (2003) Identification of a Cancer Stem Cell in Human Brain Tumors. Cancer Res 63:5821–5828
20. Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB (2004) Identification of human brain tumour initiating cells. Nature 432:396–401
21. Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura S, Nakashima S, Kunisada T, Iwama T (2008) Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells. J Biol Chem 283:10958–10966
22. Stupp R, Hegi ME (2007) Targeting brain-tumor stem cells. Nat Biotechnol 25:193–194
23. Stupp R, Tonn JC, Brada M, and On behalf of the ESMO Guidelines Working Group (2010) High-grade malignant glioma: eSMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Onc 21:v190–v193
24. Tsuji-Takayama K, Inoue T, Ijiri Y, Otani T, Motoda R, Nakamura S, Orita K (2004) Demethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cells. Biochem Biophys Res Commun 323(1):86–90
25. Uhl M, Aulwurm S, Wischhusen J, Weiler M, Ma JY, Almirez R, Mangadu R, Liu YW, Platten M, Herrlinger U, Murphy A, Wong DH, Wick W, Higgins LS, Weller M (2004) SD-208, a Novel Transforming Growth Factor ß Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma Cells In vitro and In vivo. Cancer Res 64:7954–7961
26. Veeravalli KK, Rao JS (2012) MMP-9 and uPAR regulated glioma cell migration. Cell Adh Migr 6(6):509–512
27. Vlashi E, Lagadec C, Vergnes L, Matsutani T, Masui K, Poulou M, Popescu R, Della Donna L, Evers P, Dekmezian C, Reue K, Christofk H, Mischel PS, Pajonk F (2011) Metabolic state of glioma stem cells and nontumorigenic cells. PNAS 108:16062–16067
28. Xu ZY, Wang K, Li XQ, Chen S, Deng JM, Cheng Y, Wang ZG (2013) The ABCG2 transporter is a key molecular determinant of the efficacy of sonodynamic therapy with Photofrin in glioma stem-like cells. Ultrasonics 53(1):232–238
29. Yin M, Zhang L, Sun XM, Mao LF, Pan J (2010) Lack of apoE causes alteration of cytokines expression in young mice liver. Mol Biol Rep 37(4):2049–2054
30. Ying Z, Li Y, Wu J, Zhu X, Yang Y, Tian H, Li W, Hu B, Cheng SY, Li M (2013) Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-like Phenotype. Cancer Res 73:990–999
31. Zhang D, Jing Z, Qiu B, Wu A, Wang Y (2011) Temozolomide decreases invasion of glioma stem cells by down-regulating TGF-β2. Oncol Rep 26:901–908