Demethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cells

Biochemical and Biophysical Research Communications

Volumn 323, Issue 1, 2004, Pages 86-90

  Tsuji Takayama, Kazue ^a   Inoue, Toshiya ^a   Ijiri, Yoshihiro ^a   Otani, Takeshi ^a   Motoda, Ryuichi ^a   Nakamura, Shuji ^a   Orita, Kunzo ^a  

^a HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

5 Azacytidine; Demethylation; Differentiation; EB; ES; H19; Methylation; SSEA 1

Indexed keywords

ALKALINE PHOSPHATASE; AZACITIDINE; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN; PROTEIN NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; STAGE SPECIFIC EMBRYO ANTIGEN 1; TRANSCRIPTION FACTOR NANOG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DRUG EFFECT; ENZYME ACTIVITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; STEM CELL; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOID BODY; EMBRYONIC STEM CELL; GENE EXPRESSION; REGULATOR GENE;

ALKALINE PHOSPHATASE; ANIMALS; AZACITIDINE; CELL DIFFERENTIATION; CELL LINE; DNA METHYLATION; EMBRYO; ENZYME INHIBITORS; FLOW CYTOMETRY; METHYLATION; MICE; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, UNTRANSLATED; STEM CELLS; SULFITES;

EID: 4444237490     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.052     Document Type: Article

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