-
1
-
-
0029610610
-
The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-beta, T-cell apoptosis, and the immune privilege of the brain
-
Weller M and Fontana A: The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-beta, T-cell apoptosis, and the immune privilege of the brain. Brain Res Brain Res Rev 21: 128-151, 1995.
-
(1995)
Brain Res Brain Res Rev
, vol.21
, pp. 128-151
-
-
Weller, M.1
Fontana, A.2
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996, 2005.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
3
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, et al: Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
4
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al: Identification of human brain tumour initiating cells. Nature 432: 396-401, 2004.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
5
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R, Binda E, Orfanelli U, et al: Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64: 7011-7021, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
-
6
-
-
11244293572
-
Isolation of cancer stem cells from adult glioblastoma multiforme
-
Yuan X, Curtin J, Xiong Y, et al: Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23: 9392-9400, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 9392-9400
-
-
Yuan, X.1
Curtin, J.2
Xiong, Y.3
-
7
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
Hemmati HD, Nakano I, Lazareff JA, et al: Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 100: 15178-15183, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
-
8
-
-
0034673243
-
Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via up-regulation of alpha(V)beta(3) integrin expression
-
Platten M, Wick W, Wild-Bode C, Aulwurm S, Dichgans J and Weller M: Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via up-regulation of alpha(V)beta(3) integrin expression. Biochem Biophys Res Commun 268: 607-611, 2000.
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 607-611
-
-
Platten, M.1
Wick, W.2
Wild-Bode, C.3
Aulwurm, S.4
Dichgans, J.5
Weller, M.6
-
9
-
-
0034765067
-
Glioma cell invasion: Regulation of metalloproteinase activity by TGF-beta
-
Wick W, Platten M and Weller M: Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta. J Neurooncol 53: 177-185, 2001.
-
(2001)
J Neurooncol
, vol.53
, pp. 177-185
-
-
Wick, W.1
Platten, M.2
Weller, M.3
-
10
-
-
68949092126
-
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2
-
Baumann F, Leukel P, Doerfelt A, et al: Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro Oncol 11: 368-380, 2009.
-
(2009)
Neuro Oncol
, vol.11
, pp. 368-380
-
-
Baumann, F.1
Leukel, P.2
Doerfelt, A.3
-
11
-
-
0035873075
-
Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2
-
Wick W, Grimmel C, Wild-Bode C, Platten M, Arpin M and Weller M: Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2. J Neurosci 21: 3360-3368, 2001.
-
(2001)
J Neurosci
, vol.21
, pp. 3360-3368
-
-
Wick, W.1
Grimmel, C.2
Wild-Bode, C.3
Platten, M.4
Arpin, M.5
Weller, M.6
-
12
-
-
34547187636
-
Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: From preclinical to phase I/II studies
-
Hau P, Jachimczak P, Schlingensiepen R, et al: Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies. Oligonucleotides 17: 201-212, 2007.
-
(2007)
Oligonucleotides
, vol.17
, pp. 201-212
-
-
Hau, P.1
Jachimczak, P.2
Schlingensiepen, R.3
-
13
-
-
33745962224
-
Increased concentrations of transforming growth factor beta1 and beta2 in the plasma of patients with glioblastoma
-
Schneider T, Sailer M, Ansorge S, Firsching R and Reinhold D: Increased concentrations of transforming growth factor beta1 and beta2 in the plasma of patients with glioblastoma. J Neurooncol 79: 61-65, 2006.
-
(2006)
J Neurooncol
, vol.79
, pp. 61-65
-
-
Schneider, T.1
Sailer, M.2
Ansorge, S.3
Firsching, R.4
Reinhold, D.5
-
14
-
-
33749262441
-
Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1 alpha-mediated induction of CXCL12
-
Tabatabai G, Frank B, Mohle R, Weller M and Wick W: Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1 alpha-mediated induction of CXCL12. Brain 129: 2426-2435, 2006.
-
(2006)
Brain
, vol.129
, pp. 2426-2435
-
-
Tabatabai, G.1
Frank, B.2
Mohle, R.3
Weller, M.4
Wick, W.5
-
15
-
-
33748043985
-
Temozolomide-mediated radiation enhancement in glioblastoma: A report on underlying mechanisms
-
Chakravarti A, Erkkinen MG, Nestler U, et al: Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms. Clin Cancer Res 12: 4738-4746, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4738-4746
-
-
Chakravarti, A.1
Erkkinen, M.G.2
Nestler, U.3
-
17
-
-
33751297619
-
Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas
-
Pellegatta S, Poliani PL, Corno D, et al: Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas. Cancer Res 66: 10247-10252, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 10247-10252
-
-
Pellegatta, S.1
Poliani, P.L.2
Corno, D.3
-
18
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, et al: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760, 2006.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
-
19
-
-
34447648954
-
Expression of MHC I and NK ligands on human CD133+ glioma cells: Possible targets of immunotherapy
-
Wu A, Wiesner S, Xiao J, et al: Expression of MHC I and NK ligands on human CD133+ glioma cells: possible targets of immunotherapy. J Neurooncol 83: 121-131, 2007.
-
(2007)
J Neurooncol
, vol.83
, pp. 121-131
-
-
Wu, A.1
Wiesner, S.2
Xiao, J.3
-
20
-
-
5644248080
-
RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo
-
Friese MA, Wischhusen J, Wick W, et al: RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo. Cancer Res 64: 7596-7603, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 7596-7603
-
-
Friese, M.A.1
Wischhusen, J.2
Wick, W.3
-
21
-
-
0035352398
-
Immunologic approaches to therapy for brain tumors
-
Paul DB and Kruse CA: Immunologic approaches to therapy for brain tumors. Curr Neurol Neurosci Rep 1: 238-244, 2001.
-
(2001)
Curr Neurol Neurosci Rep
, vol.1
, pp. 238-244
-
-
Paul, D.B.1
Kruse, C.A.2
-
22
-
-
79960790320
-
IL-10 and TGF-beta2 are overexpressed in tumor spheres cultured from human gliomas
-
Qiu B, Zhang D, Wang C, et al: IL-10 and TGF-beta2 are overexpressed in tumor spheres cultured from human gliomas. Mol Biol Rep 38: 3585-3591, 2011.
-
(2011)
Mol Biol Rep
, vol.38
, pp. 3585-3591
-
-
Qiu, B.1
Zhang, D.2
Wang, C.3
-
23
-
-
70450203744
-
Glioma stem cell research for the development of immunotherapy
-
Ji J, Black KL and Yu JS: Glioma stem cell research for the development of immunotherapy. Neurosurg Clin N Am 21: 159-166, 2010.
-
(2010)
Neurosurg Clin N Am
, vol.21
, pp. 159-166
-
-
Ji, J.1
Black, K.L.2
Yu, J.S.3
-
24
-
-
63249123273
-
TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma
-
Penuelas S, Anido J, Prieto-Sanchez RM, et al: TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma. Cancer Cell 15: 315-327, 2009.
-
(2009)
Cancer Cell
, vol.15
, pp. 315-327
-
-
Penuelas, S.1
Anido, J.2
Prieto-Sanchez, R.M.3
-
25
-
-
76049114698
-
Immunobiological characterization of cancer stem cells isolated from glioblastoma patients
-
Di Tomaso T, Mazzoleni S, Wang E, et al: Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. Clin Cancer Res 16: 800-813, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 800-813
-
-
Di Tomaso, T.1
Mazzoleni, S.2
Wang, E.3
-
28
-
-
48649104080
-
Temozolomide preferentially depletes cancer stem cells in glioblastoma
-
Beier D, Rohrl S, Pillai DR, et al: Temozolomide preferentially depletes cancer stem cells in glioblastoma. Cancer Res 68: 5706-5715, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 5706-5715
-
-
Beier, D.1
Rohrl, S.2
Pillai, D.R.3
-
29
-
-
0035865158
-
Malignant glioma biology: Role for TGF-beta in growth, motility, angiogenesis, and immune escape
-
Platten M, Wick W and Weller M: Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape. Microsc Res Tech 52: 401-410, 2001.
-
(2001)
Microsc Res Tech
, vol.52
, pp. 401-410
-
-
Platten, M.1
Wick, W.2
Weller, M.3
-
30
-
-
33846821916
-
High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
-
Bruna A, Darken RS, Rojo F, et al: High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell 11: 147-160, 2007.
-
(2007)
Cancer Cell
, vol.11
, pp. 147-160
-
-
Bruna, A.1
Darken, R.S.2
Rojo, F.3
|