Identification of small molecule inhibitors of cisplatin-induced hair cell death: Results of a 10,000 compound screen in the zebrafish lateral line

Otology and Neurotology

Volumn 36, Issue 3, 2015, Pages 519-525

  Thomas, Andrew J ^a   Wu, Patricia ^a   Raible, David W ^a   Rubel, Edwin W ^a   Simon, Julian A ^b   Ou, Henry C ^a,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c SEATTLE CHILDREN S HOSPITAL   (United States)

Author keywords

Cisplatin; Hair cell; Ototoxicity; Protection

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; NEUROPROTECTIVE AGENT;

ANIMAL; CELL DEATH; CHEMICALLY INDUCED; COCHLEAR HAIR CELL; DOSE RESPONSE; DRUG EFFECTS; HEARING LOSS; LATERAL LINE SYSTEM; PRECLINICAL STUDY; ZEBRA FISH;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DEATH; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HAIR CELLS, AUDITORY; HEARING LOSS; LATERAL LINE SYSTEM; NEUROPROTECTIVE AGENTS; ZEBRAFISH;

EID: 84923629631     PISSN: 15317129     EISSN: 15374505     Source Type: Journal    
DOI: 10.1097/MAO.0000000000000487     Document Type: Article

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