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Volumn 22, Issue 1, 2015, Pages 35-45

Microsatellite unstable gastrointestinal neuroendocrine carcinomas: A new clinicopathologic entity

Author keywords

Gene methylation; MANEC; Microsatellite instability; Mismatch repair; NEC; Neuroendocrine carcinomas

Indexed keywords

B RAF KINASE; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

EID: 84923618154     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-14-0410     Document Type: Article
Times cited : (132)

References (46)
  • 1
    • 64649096900 scopus 로고    scopus 로고
    • Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and leukemia group B protocol 89803
    • Bertagnolli MM, Niedzwiecki D, Compton CC, Hahn HP, Hall M, Damas B, Jewell SD, Mayer RJ, Goldberg RM, Saltz LB et al. 2009 Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. Journal of Clinical Oncology 27 1814-1821. (doi:10.1200/JCO.2008.18.2071)
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 1814-1821
    • Bertagnolli, M.M.1    Niedzwiecki, D.2    Compton, C.C.3    Hahn, H.P.4    Hall, M.5    Damas, B.6    Jewell, S.D.7    Mayer, R.J.8    Goldberg, R.M.9    Saltz, L.B.10
  • 2
    • 0034661742 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability
    • Bevilacqua RA & Simpson AJ 2000 Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability. International Journal of Cancer 87 200-203. (doi:10.1002/1097-0215(20000715)87:2<200::AID-IJC7>3.0.CO;2-I)
    • (2000) International Journal of Cancer , vol.87 , pp. 200-203
    • Bevilacqua, R.A.1    Simpson, A.J.2
  • 3
    • 67651173046 scopus 로고    scopus 로고
    • Promoter methylation in the genesis of gastrointestinal cancer
    • Boland CR, Shin SK & Goel A 2009 Promoter methylation in the genesis of gastrointestinal cancer. Yonsei Medical Journal 50 309-321. (doi:10.3349/ymj.2009.50.3.309)
    • (2009) Yonsei Medical Journal , vol.50 , pp. 309-321
    • Boland, C.R.1    Shin, S.K.2    Goel, A.3
  • 4
    • 0033973828 scopus 로고    scopus 로고
    • Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status
    • Bras-Goncalves RA, Rosty C, Laurent-Puig P, Soulie P, Dutrillaux B & Poupon MF 2000 Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status. British Journal of Cancer 82 913-923. (doi:10.1054/bjoc.1999.1019)
    • (2000) British Journal of Cancer , vol.82 , pp. 913-923
    • Bras-Goncalves, R.A.1    Rosty, C.2    Laurent-Puig, P.3    Soulie, P.4    Dutrillaux, B.5    Poupon, M.F.6
  • 5
    • 0036742795 scopus 로고    scopus 로고
    • Small-cell neuroendocrine carcinoma displays unique profiles of tumor-suppressor gene loss in relationship to the primary site of formation
    • Dacic S, Finkelstein SD, Baksh FK, Swalsky PA, Barnes LE & Yousem SA 2002 Small-cell neuroendocrine carcinoma displays unique profiles of tumor-suppressor gene loss in relationship to the primary site of formation. Human Pathology 33 927-932. (doi:10.1053/hupa.2002.126875)
    • (2002) Human Pathology , vol.33 , pp. 927-932
    • Dacic, S.1    Finkelstein, S.D.2    Baksh, F.K.3    Swalsky, P.A.4    Barnes, L.E.5    Yousem, S.A.6
  • 6
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 concerted action BMH4-CT98-3936
    • van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hummel M, Lavender FL, Delabesse E, Davi F, Schuuring E, Garcia-Sanz R et al. 2003 Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 17 2257-2317. (doi:10.1038/sj.leu.2403202)
    • (2003) Leukemia , vol.17 , pp. 2257-2317
    • Van Dongen, J.J.1    Langerak, A.W.2    Bruggemann, M.3    Evans, P.A.4    Hummel, M.5    Lavender, F.L.6    Delabesse, E.7    Davi, F.8    Schuuring, E.9    Garcia-Sanz, R.10
  • 8
    • 0035998835 scopus 로고    scopus 로고
    • Model-based clustering, discriminant analysis, and density estimation
    • Fraley F & Raftery AE 2002 Model-based clustering, discriminant analysis, and density estimation. Journal of the American Statistical Association 97 611-631. (doi:10.1198/016214502760047131)
    • (2002) Journal of the American Statistical Association , vol.97 , pp. 611-631
    • Fraley, F.1    Raftery, A.E.2
  • 9
    • 0036058846 scopus 로고    scopus 로고
    • Genetic progression in sporadic endometrial and gastrointestinal cancers with high microsatellite instability
    • Furlan D, Casati B, Cerutti R, Facco C, Terracciano L, Capella C & Chiaravalli AM 2002 Genetic progression in sporadic endometrial and gastrointestinal cancers with high microsatellite instability. Journal of Pathology 197 603-609. (doi:10.1002/path.1162)
    • (2002) Journal of Pathology , vol.197 , pp. 603-609
    • Furlan, D.1    Casati, B.2    Cerutti, R.3    Facco, C.4    Terracciano, L.5    Capella, C.6    Chiaravalli, A.M.7
  • 10
    • 16344374853 scopus 로고    scopus 로고
    • Allelotypes and fluorescence in situ hybridization profiles of poorly differentiated endocrine carcinomas of different sites
    • Furlan D, Bernasconi B, Uccella S, Cerutti R, Carnevali I & Capella C 2005 Allelotypes and fluorescence in situ hybridization profiles of poorly differentiated endocrine carcinomas of different sites. Clinical Cancer Research 11 1765-1775. (doi:10.1158/1078-0432.CCR-04-1732)
    • (2005) Clinical Cancer Research , vol.11 , pp. 1765-1775
    • Furlan, D.1    Bernasconi, B.2    Uccella, S.3    Cerutti, R.4    Carnevali, I.5    Capella, C.6
  • 13
    • 0033176038 scopus 로고    scopus 로고
    • Microsatellite instability and allelic losses in neuroendocrine tumors of the gastro-entero-pancreatic system
    • Ghimenti C, Lonobile A, Campani D, Bevilacqua G & Caligo MA 1999 Microsatellite instability and allelic losses in neuroendocrine tumors of the gastro-entero-pancreatic system. International Journal of Oncology 15 361-366. (doi:10.3892/ijo.15.2.361)
    • (1999) International Journal of Oncology , vol.15 , pp. 361-366
    • Ghimenti, C.1    Lonobile, A.2    Campani, D.3    Bevilacqua, G.4    Caligo, M.A.5
  • 14
    • 14644441621 scopus 로고    scopus 로고
    • Microsatellite instability and DNA mismatch repair deficiency testing in hereditary and sporadic gastrointestinal cancers
    • Gologan A & Sepulveda AR 2005 Microsatellite instability and DNA mismatch repair deficiency testing in hereditary and sporadic gastrointestinal cancers. Clinics in Laboratory Medicine 25 179-196. (doi:10.1016/j.cll.2004.12.001)
    • (2005) Clinics in Laboratory Medicine , vol.25 , pp. 179-196
    • Gologan, A.1    Sepulveda, A.R.2
  • 18
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y, Peinado MA, Malkhosyan S, Shibata D & Perucho M 1993 Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363 558-561. (doi:10.1038/363558a0)
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3    Shibata, D.4    Perucho, M.5
  • 19
    • 0031017268 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
    • Kane MF, Loda M, Gaida GM, Lipman J, Mishra R, Goldman H, Jessup JM & Kolodner R 1997 Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Research 57 808-811.
    • (1997) Cancer Research , vol.57 , pp. 808-811
    • Kane, M.F.1    Loda, M.2    Gaida, G.M.3    Lipman, J.4    Mishra, R.5    Goldman, H.6    Jessup, J.M.7    Kolodner, R.8
  • 20
    • 33947546541 scopus 로고    scopus 로고
    • Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: A national cancer institute-national surgical adjuvant breast and bowel project collaborative study
    • Kim GP, Colangelo LH, Wieand HS, Paik S, Kirsch IR, Wolmark N & Allegra CJ 2007 Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study. Journal of Clinical Oncology 25 767-772. (doi:10.1200/JCO.2006.05.8172)
    • (2007) Journal of Clinical Oncology , vol.25 , pp. 767-772
    • Kim, G.P.1    Colangelo, L.H.2    Wieand, H.S.3    Paik, S.4    Kirsch, I.R.5    Wolmark, N.6    Allegra, C.J.7
  • 21
    • 84903648563 scopus 로고    scopus 로고
    • High-grade poorly differentiated neuroendocrine carcinomas of the gastroenteropancreatic system: From morphology to proliferation and back
    • La Rosa S & Sessa F 2014 High-grade poorly differentiated neuroendocrine carcinomas of the gastroenteropancreatic system: from morphology to proliferation and back. Endocrine Pathology 25 193-198. (doi:10.1007/s12022-014-9316-9)
    • (2014) Endocrine Pathology , vol.25 , pp. 193-198
    • La Rosa, S.1    Sessa, F.2
  • 23
    • 80053195715 scopus 로고    scopus 로고
    • Histologic characterization and improved prognostic evaluation of 209 gastric neuroendocrine neoplasms
    • La Rosa S, Inzani F, Vanoli A, Klersy C, Dainese L, Rindi G, Capella C, Bordi C & Solcia E 2011 Histologic characterization and improved prognostic evaluation of 209 gastric neuroendocrine neoplasms. Human Pathology 42 1373-1384. (doi:10.1016/j.humpath.2011.01.018)
    • (2011) Human Pathology , vol.42 , pp. 1373-1384
    • La Rosa, S.1    Inzani, F.2    Vanoli, A.3    Klersy, C.4    Dainese, L.5    Rindi, G.6    Capella, C.7    Bordi, C.8    Solcia, E.9
  • 24
    • 84859041362 scopus 로고    scopus 로고
    • Colorectal poorly differentiated neuroendocrine carcinomas and mixed adeno-neuroendocrine carcinomas: Insights into the diagnostic immuno-phenotype, assessment of methylation profile, and search for prognostic markers
    • La Rosa S, Marando A, Furlan D, Sahnane N & Capella C 2012a Colorectal poorly differentiated neuroendocrine carcinomas and mixed adeno-neuroendocrine carcinomas: insights into the diagnostic immuno-phenotype, assessment of methylation profile, and search for prognostic markers. American Journal of Surgical Pathology 36 601-611. (doi:10.1097/PAS.0b013e318242e21c)
    • (2012) American Journal of Surgical Pathology , vol.36 , pp. 601-611
    • La Rosa, S.1    Marando, A.2    Furlan, D.3    Sahnane, N.4    Capella, C.5
  • 25
    • 84859087024 scopus 로고    scopus 로고
    • Mixed adenoneuro-endocrine carcinomas (MANECs) of the gastrointestinal tract: An update
    • La Rosa S, Marando A, Sessa F & Capella C 2012b Mixed adenoneuro-endocrine carcinomas (MANECs) of the gastrointestinal tract: an update. Cancers 4 11-30. (doi:10.3390/cancers4010011)
    • (2012) Cancers , vol.4 , pp. 11-30
    • La Rosa, S.1    Marando, A.2    Sessa, F.3    Capella, C.4
  • 26
    • 39549112569 scopus 로고    scopus 로고
    • Molecular genetic events in gastrointestinal and pancreatic neuroendocrine tumors
    • Lubensky IA & Zhuang Z 2007 Molecular genetic events in gastrointestinal and pancreatic neuroendocrine tumors. Endocrine Pathology 18 156-162. (doi:10.1007/s12022-007-9007-x)
    • (2007) Endocrine Pathology , vol.18 , pp. 156-162
    • Lubensky, I.A.1    Zhuang, Z.2
  • 27
    • 84859887640 scopus 로고    scopus 로고
    • Large cell neuroendocrine carcinoma arising in a sessile serrated adenoma: A novel observation
    • Naert K & Dupre MP 2012 Large cell neuroendocrine carcinoma arising in a sessile serrated adenoma: a novel observation. Human Pathology 43 757-760. (doi:10.1016/j.humpath.2011.07.022)
    • (2012) Human Pathology , vol.43 , pp. 757-760
    • Naert, K.1    Dupre, M.P.2
  • 28
    • 17744384708 scopus 로고    scopus 로고
    • High-grade neuroendocrine carcinoma of the ampulla of vater: A clinicopathologic and immunohistochemical analysis of 14 cases
    • Nassar H, Albores-Saavedra J & Klimstra DS 2005 High-grade neuroendocrine carcinoma of the ampulla of vater: a clinicopathologic and immunohistochemical analysis of 14 cases. American Journal of Surgical Pathology 29 588-594. (doi:10.1097/01.pas.0000157974.05397.4f)
    • (2005) American Journal of Surgical Pathology , vol.29 , pp. 588-594
    • Nassar, H.1    Albores-Saavedra, J.2    Klimstra, D.S.3
  • 32
    • 84655175045 scopus 로고    scopus 로고
    • High-grade neuroendocrine carcinoma of the colon, long-term survival in advanced disease
    • Power DG, Asmis TR, Tang LH, Brown K & Kemeny NE 2010 High-grade neuroendocrine carcinoma of the colon, long-term survival in advanced disease. Medical Oncology 28 (Suppl 1) S169-S174. (doi:10.1007/s12032-010-9674-1)
    • (2010) Medical Oncology , vol.28 , pp. S169-S174
    • Power, D.G.1    Asmis, T.R.2    Tang, L.H.3    Brown, K.4    Kemeny, N.E.5
  • 33
    • 79956152733 scopus 로고    scopus 로고
    • Nomenclature and classification of neuroendocrine neoplasms of the digestive system
    • Ed F Bosman. Lyon: IARC Press
    • Rindi G, Arnold R & Bosman FT 2010 Nomenclature and classification of neuroendocrine neoplasms of the digestive system. In WHO Classification of Tumours of the Digestive System, Ed F Bosman. Lyon: IARC Press.
    • (2010) WHO Classification of Tumours of the Digestive System
    • Rindi, G.1    Arnold, R.2    Bosman, F.T.3
  • 35
    • 0000120766 scopus 로고
    • Estimating the dimension of a model
    • Schwarz G 1978 Estimating the dimension of a model. Annals of Statistics 6 461-464. (doi:10.1214/aos/1176344136)
    • (1978) Annals of Statistics , vol.6 , pp. 461-464
    • Schwarz, G.1
  • 37
    • 84873351920 scopus 로고    scopus 로고
    • The management of extrapulmonary poorly differentiated (high-grade) neuroendocrine carcinomas
    • Smith J & Reidy-Lagunes D 2013 The management of extrapulmonary poorly differentiated (high-grade) neuroendocrine carcinomas. Seminars in Oncology 40 100-108. (doi:10.1053/j.seminoncol.2012.11.011)
    • (2013) Seminars in Oncology , vol.40 , pp. 100-108
    • Smith, J.1    Reidy-Lagunes, D.2
  • 38
    • 84871555750 scopus 로고    scopus 로고
    • Predictive and prognosticfactors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): The NORDIC NEC study
    • Sorbye H, Welin S, Langer SW, Vestermark LW, Holt N, Osterlund P, Dueland S, Hofsli E, Guren MG, Ohrling K et al. 2013 Predictive and prognosticfactors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study. Annals of Oncology 24 152-160. (doi:10.1093/annonc/mds276)
    • (2013) Annals of Oncology , vol.24 , pp. 152-160
    • Sorbye, H.1    Welin, S.2    Langer, S.W.3    Vestermark, L.W.4    Holt, N.5    Osterlund, P.6    Dueland, S.7    Hofsli, E.8    Guren, M.G.9    Ohrling, K.10
  • 39
    • 33750460628 scopus 로고    scopus 로고
    • The mismatch repair protein status of colorectal small cell neuroendocrine carcinomas
    • Stelow EB, Moskaluk CA & Mills SE 2006 The mismatch repair protein status of colorectal small cell neuroendocrine carcinomas. American Journal of Surgical Pathology 30 1401-1404. (doi:10.1097/01.PAS.0000213272.15221.38)
    • (2006) American Journal of Surgical Pathology , vol.30 , pp. 1401-1404
    • Stelow, E.B.1    Moskaluk, C.A.2    Mills, S.E.3
  • 40
    • 0036893598 scopus 로고    scopus 로고
    • Evaluation of tumor microsatellite instability usingfive quasimonomorphic mononucleotide repeats and pentaplex PCR
    • Suraweera N, Duval A, Reperant M, Vaury C, Furlan D, Leroy K, Seruca R, Iacopetta B & Hamelin R 2002 Evaluation of tumor microsatellite instability usingfive quasimonomorphic mononucleotide repeats and pentaplex PCR. Gastroenterology 123 1804-1811. (doi:10.1053/gast.2002.37070)
    • (2002) Gastroenterology , vol.123 , pp. 1804-1811
    • Suraweera, N.1    Duval, A.2    Reperant, M.3    Vaury, C.4    Furlan, D.5    Leroy, K.6    Seruca, R.7    Iacopetta, B.8    Hamelin, R.9
  • 46
    • 77951967408 scopus 로고    scopus 로고
    • Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treated by 5-fluorouracil and leucovorin with or without oxaliplatin
    • Zaanan A, Cuilliere-Dartigues P, Guilloux A, Parc Y, Louvet C, de Gramont A, Tiret E, Dumont S, Gayet B, Validire P et al. 2010 Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treated by 5-fluorouracil and leucovorin with or without oxaliplatin. Annals of Oncology 21 772-780. (doi:10.1093/annonc/mdp383)
    • (2010) Annals of Oncology , vol.21 , pp. 772-780
    • Zaanan, A.1    Cuilliere-Dartigues, P.2    Guilloux, A.3    Parc, Y.4    Louvet, C.5    De Gramont, A.6    Tiret, E.7    Dumont, S.8    Gayet, B.9    Validire, P.10


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