Gallic acid isolated from Spirogyra sp. improves cardiovascular disease through a vasorelaxant and antihypertensive effect

Environmental Toxicology and Pharmacology

Volumn 39, Issue 2, 2015, Pages 764-772

  Kang, Nalae ^a   Lee, Ji Hyeok ^a   Lee, WonWoo ^a   Ko, Ju Young ^a   Kim, Eun A ^a   Kim, Jin Soo ^b   Heu, Min Soo ^b   Kim, Gwang Hoon ^c   Jeon, You Jin ^a  

^a Jeju National University   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Kongju National University   (South Korea)

Author keywords

Antihypertensive effect; Cardiovascular diseases; Gallic acid; Spyrogira sp.; Vasorelaxation

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GALLIC ACID; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHOSPHODIESTERASE III; ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; NOS3 PROTEIN, HUMAN; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DIASTOLIC BLOOD PRESSURE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYDROGEN BOND; HYPERTENSION; IC50; MALE; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPIROGYRA; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; UMBILICAL VEIN ENDOTHELIAL CELL; VASODILATATION; WESTERN BLOTTING; ANIMAL; CARDIOVASCULAR DISEASES; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; PATHOPHYSIOLOGY;

CHLOROPHYTA; RATTUS; SPIROGYRA SP.;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; ANTIOXIDANTS; CARDIOVASCULAR DISEASES; CELLS, CULTURED; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; GALLIC ACID; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, INBRED SHR; SPIROGYRA; VASODILATOR AGENTS;

EID: 84923593025     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2015.02.006     Document Type: Article

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