The DPP-4 inhibitor linagliptin and the GLP-1 receptor agonist exendin-4 improve endothelium-dependent relaxation of rat mesenteric arteries in the presence of high glucose

Pharmacological Research

Volumn 94, Issue , 2015, Pages 26-33

  Salheen, S M ^a   Panchapakesan, U ^b   Pollock, C A ^a   Woodman, O L ^a  

^a RMIT UNIVERSITY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Dipeptidylpeptidase 4 inhibitors; Endothelium dependent relaxation; Exendin 4; High glucose; Superoxide anion

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYLMETHYL] 1H PYRAZOLE; APAMIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; LINAGLIPTIN; LUCIGENIN; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; PYROGALLOL; SITAGLIPTIN; SUPEROXIDE; SUPEROXIDE DISMUTASE; VILDAGLIPTIN; ANTIOXIDANT; BIOLOGICAL FACTOR; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION FACTOR; GLUCOSE; PEPTIDE; VENOM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTERY DILATATION; ARTICLE; CELL FUNCTION; CELL ISOLATION; CHEMOLUMINESCENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; ENDOTHELIUM; ENZYME INHIBITION; HYPEROSMOTIC STRESS; IN VITRO STUDY; MALE; MESENTERIC ARTERY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; AGONISTS; ANIMAL; DRUG EFFECTS; METABOLISM; MUSCLE RELAXATION; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL FACTORS; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; ENDOTHELIUM; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; GLUCOSE; IN VITRO TECHNIQUES; LINAGLIPTIN; MALE; MESENTERIC ARTERIES; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; PEPTIDES; PYROGALLOL; RATS; RATS, WISTAR; SUPEROXIDES; VENOMS;

EID: 84923574254     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2015.02.003     Document Type: Article

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