CMC determination of nonionic surfactants in protein formulations using ultrasonic resonance technology

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 92, Issue , 2015, Pages 8-14

  Horiuchi, Shohei ^a,b   Winter, Gerhard ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Critical micelle concentration; Dynamic light scattering; Protein formulation; Surface tensiometry; Surfactant; Ultrasonic resonance technology

Indexed keywords

ARGININE; NONIONIC SURFACTANT; OMALIZUMAB; POLYSORBATE 20; PROTEIN; BIOLOGICAL PRODUCT; MICELLE; POLYSORBATE; SURFACTANT;

AQUEOUS SOLUTION; ARTICLE; COMPARATIVE STUDY; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG FORMULATION; DRUG SCREENING; LIGHT SCATTERING; MICELLIZATION; PROTEIN ANALYSIS; PROTEIN DENATURATION; PROTEIN FORMULATION; SURFACE TENSION; TITRIMETRY; ULTRASONIC RESONANCE TECHNOLOGY; WATER STRUCTURE; ADSORPTION; CHEMISTRY; ECHOGRAPHY; MEDICINAL CHEMISTRY; MICELLE; PHOTON CORRELATION SPECTROSCOPY; PROCEDURES;

ADSORPTION; ARGININE; BIOLOGICAL PRODUCTS; CHEMISTRY, PHARMACEUTICAL; DYNAMIC LIGHT SCATTERING; MICELLES; POLYSORBATES; PROTEINS; SURFACE TENSION; SURFACE-ACTIVE AGENTS; ULTRASONOGRAPHY;

EID: 84923557703     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.02.005     Document Type: Article

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