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Volumn 9, Issue 3, 2015, Pages 552-562

Structural modulation of gut microbiota during alleviation of type 2 diabetes with a Chinese herbal formula

Author keywords

[No Author keywords available]

Indexed keywords

DIABETES; GENE EXPRESSION; HEALTH RISK; HERB; IDENTIFICATION KEY; MEDICINE; METABOLISM; MICROBIOLOGY; SPECIES DIVERSITY;

EID: 84923545804     PISSN: 17517362     EISSN: 17517370     Source Type: Journal    
DOI: 10.1038/ismej.2014.177     Document Type: Article
Times cited : (379)

References (55)
  • 1
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications Part 1 diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Alberti KG, Zimmet PZ. (1998). Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15: 539-553.
    • (1998) Diabet Med , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 2
    • 80052278497 scopus 로고    scopus 로고
    • Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: Molecular mechanisms and probiotic treatment
    • Amar J, Chabo C, Waget A, Klopp P, Vachoux C, Bermúdez-Humarán LG et al. (2011). Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol Med 3: 559-572.
    • (2011) EMBO Mol Med , vol.3 , pp. 559-572
    • Amar, J.1    Chabo, C.2    Waget, A.3    Klopp, P.4    Vachoux, C.5    Bermúdez-Humarán, L.G.6
  • 4
    • 57449095009 scopus 로고    scopus 로고
    • Bacterial succession in the colon during childhood and adolescence: Molecular studies in a southern Indian village
    • Balamurugan R, Janardhan HP, George S, Chittaranjan SP, Ramakrishna BS. (2008). Bacterial succession in the colon during childhood and adolescence: molecular studies in a southern Indian village. Am J Clin Nutr 88: 1643-1647.
    • (2008) Am J Clin Nutr , vol.88 , pp. 1643-1647
    • Balamurugan, R.1    Janardhan, H.P.2    George, S.3    Chittaranjan, S.P.4    Ramakrishna, B.S.5
  • 5
    • 84867024598 scopus 로고    scopus 로고
    • Gut microbiota composition is correlated to grid floor induced stress and behavior in the BALB/c mouse
    • Bangsgaard Bendtsen KM, Krych L, Sorensen DB, Pang W, Nielsen DS, Josefsen K et al. (2012). Gut microbiota composition is correlated to grid floor induced stress and behavior in the BALB/c mouse. PLoS One 7: e46231.
    • (2012) PLoS One , vol.7 , pp. e46231
    • Bangsgaard Bendtsen, K.M.1    Krych, L.2    Sorensen, D.B.3    Pang, W.4    Nielsen, D.S.5    Josefsen, K.6
  • 6
    • 2342494434 scopus 로고    scopus 로고
    • CANOCO Reference Manual and CanoDraw for Windows User's Guide: Software for Canonical Community Ordination (version 4.5)
    • New York
    • Braak CT, Smilauer P. (2002). CANOCO Reference Manual and CanoDraw for Windows User's Guide: Software for Canonical Community Ordination (version 4.5). Microcomputer Power: Ithaca, New York.
    • (2002) Microcomputer Power: Ithaca
    • Braak, C.T.1    Smilauer, P.2
  • 7
  • 9
    • 34848912627 scopus 로고    scopus 로고
    • Selective increases of bifidobacteria in gut microflora improve high-fatdiet-induced diabetes in mice through a mechanism associated with endotoxaemia
    • Cani PD, Neyrinck AM, Fava F, Knauf C, Burcelin RG, Tuohy KM et al. (2007b). Selective increases of bifidobacteria in gut microflora improve high-fatdiet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 50: 2374-2383.
    • (2007) Diabetologia , vol.50 , pp. 2374-2383
    • Cani, P.D.1    Neyrinck, A.M.2    Fava, F.3    Knauf, C.4    Burcelin, R.G.5    Tuohy, K.M.6
  • 10
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, Delzenne NM et al. (2008). Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57: 1470-1481.
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6
  • 11
    • 65249099918 scopus 로고    scopus 로고
    • Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
    • Cani PD, Possemiers S, Van de Wiele T, Guiot Y, Everard A, Rottier O et al. (2009). Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 58: 1091-1103.
    • (2009) Gut , vol.58 , pp. 1091-1103
    • Cani, P.D.1    Possemiers, S.2    Van De Wiele, T.3    Guiot, Y.4    Everard, A.5    Rottier, O.6
  • 13
    • 84881557235 scopus 로고    scopus 로고
    • The adoptive transfer of behavioral phenotype via the intestinal microbiota: Experimental evidence and clinical implications
    • Collins SM, Kassam Z, Bercik P. (2013). The adoptive transfer of behavioral phenotype via the intestinal microbiota: experimental evidence and clinical implications. Curr Opin Microbiol 16: 240-245.
    • (2013) Curr Opin Microbiol , vol.16 , pp. 240-245
    • Collins, S.M.1    Kassam, Z.2    Bercik, P.3
  • 14
    • 78649520016 scopus 로고    scopus 로고
    • A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults
    • Davis LM, Martinez I, Walter J, Hutkins R. (2010). A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults. Int J Food Microbiol 144: 285-292.
    • (2010) Int J Food Microbiol , vol.144 , pp. 285-292
    • Davis, L.M.1    Martinez, I.2    Walter, J.3    Hutkins, R.4
  • 15
    • 0036866628 scopus 로고    scopus 로고
    • Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. Nov., comb. Nov
    • Duncan SH, Hold GL, Harmsen HJ, Stewart CS, Flint HJ. (2002). Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. Nov., comb. Nov. Int J Syst Evol Microbiol 52: 2141-2146.
    • (2002) Int J Syst Evol Microbiol , vol.52 , pp. 2141-2146
    • Duncan, S.H.1    Hold, G.L.2    Harmsen, H.J.3    Stewart, C.S.4    Flint, H.J.5
  • 16
    • 84875369840 scopus 로고    scopus 로고
    • An opportunistic pathogen isolated from the gut of an obese human causes obesity in germfree mice
    • Fei N, Zhao L. (2013). An opportunistic pathogen isolated from the gut of an obese human causes obesity in germfree mice. ISME J 7: 880-884.
    • (2013) ISME J , vol.7 , pp. 880-884
    • Fei, N.1    Zhao, L.2
  • 17
    • 79251584066 scopus 로고    scopus 로고
    • Bifidobacteria can protect from enteropathogenic infection through production of acetate
    • Fukuda S, Toh H, Hase K, Oshima K, Nakanishi Y, Yoshimura K et al. (2011). Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature 469: 543-547.
    • (2011) Nature , vol.469 , pp. 543-547
    • Fukuda, S.1    Toh, H.2    Hase, K.3    Oshima, K.4    Nakanishi, Y.5    Yoshimura, K.6
  • 18
    • 78650037263 scopus 로고    scopus 로고
    • Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: Links with metabolic and low-grade inflammation markers
    • Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL et al. (2010). Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes 59: 3049-3057.
    • (2010) Diabetes , vol.59 , pp. 3049-3057
    • Furet, J.P.1    Kong, L.C.2    Tap, J.3    Poitou, C.4    Basdevant, A.5    Bouillot, J.L.6
  • 19
    • 0016762242 scopus 로고
    • Gemmiger formicilis, n. Gen., n. Sp., an anaerobic budding bacterium from intestines
    • Gossling J, Moore WEC. (1975). Gemmiger formicilis, n. Gen., n. Sp., an anaerobic budding bacterium from intestines. Int J Syst Bacteriol 25: 202-207.
    • (1975) Int J Syst Bacteriol , vol.25 , pp. 202-207
    • Gossling, J.1    Moore, W.E.C.2
  • 20
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. (2006). Inflammation and metabolic disorders. Nature 444: 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 21
    • 0038204299 scopus 로고    scopus 로고
    • Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats
    • Hsu FL, Liu IM, Kuo DH, Chen WC, Su HC, Cheng JT. (2003). Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats. J Nat Prod 66: 788-792.
    • (2003) J Nat Prod , vol.66 , pp. 788-792
    • Hsu, F.L.1    Liu, I.M.2    Kuo, D.H.3    Chen, W.C.4    Su, H.C.5    Cheng, J.T.6
  • 26
    • 0034030605 scopus 로고    scopus 로고
    • Baicalin synergy with beta-lactam antibiotics against methicillinresistant Staphylococcus aureus and other betalactam-resistant strains of S. Aureus
    • Liu IX, Durham DG, Richards RM. (2000). Baicalin synergy with beta-lactam antibiotics against methicillinresistant Staphylococcus aureus and other betalactam-resistant strains of S. aureus. J Pharm Pharmacol 52: 361-366.
    • (2000) J Pharm Pharmacol , vol.52 , pp. 361-366
    • Liu, I.X.1    Durham, D.G.2    Richards, R.M.3
  • 27
    • 29144464937 scopus 로고    scopus 로고
    • UniFrac: A new phylogenetic method for comparing microbial communities
    • Lozupone C, Knight R. (2005). UniFrac: a new phylogenetic method for comparing microbial communities. Appl Environ Microbiol 71: 8228-8235.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 8228-8235
    • Lozupone, C.1    Knight, R.2
  • 29
    • 79955619107 scopus 로고    scopus 로고
    • Pharmacokinetics, tissue distribution and relative bioavailability of puerarin solid lipid nanoparticles following oral administration
    • Luo CF, Yuan M, Chen MS, Liu SM, Zhu L, Huang BYet al. (2011). Pharmacokinetics, tissue distribution and relative bioavailability of puerarin solid lipid nanoparticles following oral administration. Int J Pharm 410: 138-144.
    • (2011) Int J Pharm , vol.410 , pp. 138-144
    • Luo, C.F.1    Yuan, M.2    Chen, M.S.3    Liu, S.M.4    Zhu, L.5    Huang Byet, A.L.6
  • 30
    • 84875312220 scopus 로고    scopus 로고
    • Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity
    • Park DY, Ahn YT, Park SH, Huh CS, Yoo SR, Yu R et al. (2013). Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity. PLoS One 8: e59470.
    • (2013) PLoS One , vol.8 , pp. e59470
    • Park, D.Y.1    Ahn, Y.T.2    Park, S.H.3    Huh, C.S.4    Yoo, S.R.5    Yu, R.6
  • 31
    • 84867074831 scopus 로고    scopus 로고
    • A metagenome-wide association study of gut microbiota in type 2 diabetes
    • Qin J, Li Y, Cai Z, Li S, Zhu J, Zhang F et al. (2012). A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490: 55-60.
    • (2012) Nature , vol.490 , pp. 55-60
    • Qin, J.1    Li, Y.2    Cai, Z.3    Li, S.4    Zhu, J.5    Zhang, F.6
  • 32
    • 0023182919 scopus 로고
    • Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae
    • Rabbani GH, Butler T, Knight J, Sanyal SC, Alam K. (1987). Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae. J Infect Dis 155: 979-984.
    • (1987) J Infect Dis , vol.155 , pp. 979-984
    • Rabbani, G.H.1    Butler, T.2    Knight, J.3    Sanyal, S.C.4    Alam, K.5
  • 34
    • 0038005028 scopus 로고    scopus 로고
    • Reclassification of Bacteroides putredinis (Weinberg et al 1937) in a new genus Alistipes gen. Nov., as Alistipes putredinis comb. Nov., and description of Alistipes finegoldii sp. Nov., from human sources
    • Rautio M, Eerola E, Vaisanen-Tunkelrott ML, Molitoris D, Lawson P, Collins MD et al. (2003). Reclassification of Bacteroides putredinis (Weinberg et al., 1937) in a new genus Alistipes gen. Nov., as Alistipes putredinis comb. Nov., and description of Alistipes finegoldii sp. Nov., from human sources. Syst Appl Microbiol 26: 182-188.
    • (2003) Syst Appl Microbiol , vol.26 , pp. 182-188
    • Rautio, M.1    Eerola, E.2    Vaisanen-Tunkelrott, M.L.3    Molitoris, D.4    Lawson, P.5    Collins, M.D.6
  • 35
    • 80054851581 scopus 로고    scopus 로고
    • Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome
    • Saulnier DM, Riehle K, Mistretta TA, Diaz MA, Mandal D, Raza S et al. (2011). Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome. Gastroenterology 141: 1782-1791.
    • (2011) Gastroenterology , vol.141 , pp. 1782-1791
    • Saulnier, D.M.1    Riehle, K.2    Mistretta, T.A.3    Diaz, M.A.4    Mandal, D.5    Raza, S.6
  • 36
    • 33747364002 scopus 로고    scopus 로고
    • Molecular profiling of the Clostridium leptum subgroup in human fecal microflora by PCR-denaturing gradient gel electrophoresis and clone library analysis
    • Shen J, Zhang B, Wei G, Pang X, Wei H, Li M et al. (2006). Molecular profiling of the Clostridium leptum subgroup in human fecal microflora by PCR-denaturing gradient gel electrophoresis and clone library analysis. Appl Environ Microbiol 72: 5232-5238.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 5232-5238
    • Shen, J.1    Zhang, B.2    Wei, G.3    Pang, X.4    Wei, H.5    Li, M.6
  • 37
    • 84897960120 scopus 로고    scopus 로고
    • An increase in the Akkermansia spp. Population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice
    • Shin NR, Lee JC, Lee HY, Kim MS, Whon TW, Lee MS et al. (2013). An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice. Gut 63: 727-735.
    • (2013) Gut , vol.63 , pp. 727-735
    • Shin, N.R.1    Lee, J.C.2    Lee, H.Y.3    Kim, M.S.4    Whon, T.W.5    Lee, M.S.6
  • 38
    • 33745861300 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • Shoelson SE. (2006). Inflammation and insulin resistance. J Clin Invest 116: 1793-1801.
    • (2006) J Clin Invest , vol.116 , pp. 1793-1801
    • Shoelson, S.E.1
  • 39
    • 55949124035 scopus 로고    scopus 로고
    • From the cover: Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermudez-Humaran LG, Gratadoux JJ et al. (2008). From the cover: Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA 105: 16731-16736.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3    Lakhdari, O.4    Bermudez-Humaran, L.G.5    Gratadoux, J.J.6
  • 40
    • 70349971732 scopus 로고    scopus 로고
    • Berberine and Coptidis rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations
    • Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y. (2009). Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations. J Ethnopharmacol 126: 5-17.
    • (2009) J Ethnopharmacol , vol.126 , pp. 5-17
    • Tang, J.1    Feng, Y.2    Tsao, S.3    Wang, N.4    Curtain, R.5    Wang, Y.6
  • 41
    • 84888009471 scopus 로고    scopus 로고
    • NMR-based metabonomic study of Chinese medicine Gegen Qinlian Decoction as an effective treatment for type 2 diabetes in rats
    • Tian N, Wang J, Wang P, Song X, Yang M, Kong L. (2013). NMR-based metabonomic study of Chinese medicine Gegen Qinlian Decoction as an effective treatment for type 2 diabetes in rats. Metabolomics 9: 1228-1242.
    • (2013) Metabolomics , vol.9 , pp. 1228-1242
    • Tian, N.1    Wang, J.2    Wang, P.3    Song, X.4    Yang, M.5    Kong, L.6
  • 42
    • 79956141290 scopus 로고    scopus 로고
    • Clinical observations on the dose-effect relationship of Gegen Qin Lian Decoction on 54 out-patients with type 2 diabetes
    • Tong XL, Zhao HL, Lian FM, Zhou Q, Xia L, Zhang JC et al. (2011). Clinical observations on the dose-effect relationship of Gegen Qin Lian Decoction on 54 out-patients with type 2 diabetes. J Traditional Chinese Med 31: 56-59.
    • (2011) J Traditional Chinese Med , vol.31 , pp. 56-59
    • Tong, X.L.1    Zhao, H.L.2    Lian, F.M.3    Zhou, Q.4    Xia, L.5    Zhang, J.C.6
  • 43
    • 41849127118 scopus 로고    scopus 로고
    • Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
    • Turnbaugh PJ, Backhed F, Fulton L, Gordon JI. (2008). Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3: 213-223.
    • (2008) Cell Host Microbe , vol.3 , pp. 213-223
    • Turnbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 44
    • 70350608018 scopus 로고    scopus 로고
    • Baicalin reduces mitochondrial damage in streptozotocin-induced diabetic Wistar rats
    • Waisundara VY, Hsu A, Tan BK, Huang D. (2009). Baicalin reduces mitochondrial damage in streptozotocin-induced diabetic Wistar rats. Diabetes Metab Res Rev 25: 671-677.
    • (2009) Diabetes Metab Res Rev , vol.25 , pp. 671-677
    • Waisundara, V.Y.1    Hsu, A.2    Tan, B.K.3    Huang, D.4
  • 45
    • 84855923925 scopus 로고    scopus 로고
    • Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
    • Wang T, Cai G, Qiu Y, Fei N, Zhang M, Pang X et al. (2011). Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers. ISME J 6: 320-329.
    • (2011) ISME J , vol.6 , pp. 320-329
    • Wang, T.1    Cai, G.2    Qiu, Y.3    Fei, N.4    Zhang, M.5    Pang, X.6
  • 46
    • 82955247909 scopus 로고    scopus 로고
    • IDF diabetes atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
    • Whiting DR, Guariguata L, Weil C, Shaw J. (2011). IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract 94: 311-321.
    • (2011) Diabetes Res Clin Pract , vol.94 , pp. 311-321
    • Whiting, D.R.1    Guariguata, L.2    Weil, C.3    Shaw, J.4
  • 47
    • 84895077527 scopus 로고    scopus 로고
    • A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome
    • Xiao S, Fei N, Pang X, Shen J, Wang L, Zhang B et al. (2013). A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome. FEMS Microbiol Ecol 87: 357-367.
    • (2013) FEMS Microbiol Ecol , vol.87 , pp. 357-367
    • Xiao, S.1    Fei, N.2    Pang, X.3    Shen, J.4    Wang, L.5    Zhang, B.6
  • 48
    • 84883416199 scopus 로고    scopus 로고
    • Prevalence and control of diabetes in Chinese adults
    • Xu Y, Wang L, He J, Bi Y, Li M, Wang T et al. (2013). Prevalence and control of diabetes in Chinese adults. JAMA 310: 948-959.
    • (2013) JAMA , vol.310 , pp. 948-959
    • Xu, Y.1    Wang, L.2    He, J.3    Bi, Y.4    Li, M.5    Wang, T.6
  • 49
    • 76349111356 scopus 로고    scopus 로고
    • Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice
    • Zhang C, Zhang M, Wang S, Han R, Cao Y, Hua W et al. (2009). Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice. ISME J 4: 232-241.
    • (2009) ISME J , vol.4 , pp. 232-241
    • Zhang, C.1    Zhang, M.2    Wang, S.3    Han, R.4    Cao, Y.5    Hua, W.6
  • 50
    • 84867746407 scopus 로고    scopus 로고
    • Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations
    • Zhang C, Zhang M, Pang X, Zhao Y, Wang L, Zhao L. (2012a). Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations. ISME J 6: 1848-1857.
    • (2012) ISME J , vol.6 , pp. 1848-1857
    • Zhang, C.1    Zhang, M.2    Pang, X.3    Zhao, Y.4    Wang, L.5    Zhao, L.6
  • 51
    • 84873714741 scopus 로고    scopus 로고
    • Anti-diabetic activities of Gegen Qinlian Decoction in high-fat diet combined with streptozotocininduced diabetic rats and in 3T3-L1 adipocytes
    • Zhang CH, Xu GL, Liu YH, Rao Y, Yu RY, Zhang ZW et al. (2013). Anti-diabetic activities of Gegen Qinlian Decoction in high-fat diet combined with streptozotocininduced diabetic rats and in 3T3-L1 adipocytes. Phytomedicine 20: 221-229.
    • (2013) Phytomedicine , vol.20 , pp. 221-229
    • Zhang, C.H.1    Xu, G.L.2    Liu, Y.H.3    Rao, Y.4    Yu, R.Y.5    Zhang, Z.W.6
  • 52
    • 84864560961 scopus 로고    scopus 로고
    • Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats
    • Zhang X, Zhao Y, Zhang M, Pang X, Xu J, Kang C et al. (2012b). Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats. PLoS One 7: e42529.
    • (2012) PLoS One , vol.7 , pp. e42529
    • Zhang, X.1    Zhao, Y.2    Zhang, M.3    Pang, X.4    Xu, J.5    Kang, C.6
  • 53
    • 47549100864 scopus 로고    scopus 로고
    • Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine
    • Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N et al. (2008). Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab 93: 2559-2565.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2559-2565
    • Zhang, Y.1    Li, X.2    Zou, D.3    Liu, W.4    Yang, J.5    Zhu, N.6
  • 54
    • 84882703646 scopus 로고    scopus 로고
    • The gut microbiota and obesity: From correlation to causality
    • Zhao L. (2013). The gut microbiota and obesity: from correlation to causality. Nat Rev Microbiol 11: 639-647.
    • (2013) Nat Rev Microbiol , vol.11 , pp. 639-647
    • Zhao, L.1
  • 55
    • 0018478128 scopus 로고
    • The metabolic fate of the effective components of puerariae. III. The metabolism of puerarin article in Chinese
    • Zhu XY, Su GY, Li ZH, Yue TL, Yan XZ, Wei HL. (1979). The metabolic fate of the effective components of puerariae. III. The metabolism of puerarin [article in Chinese]. Acta Pharm Sin 14: 349-355.
    • (1979) Acta Pharm Sin , vol.14 , pp. 349-355
    • Zhu, X.Y.1    Su, G.Y.2    Li, Z.H.3    Yue, T.L.4    Yan, X.Z.5    Wei, H.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.