Hsp90 C-terminal inhibitors exhibit antimigratory activity by disrupting the Hsp90α/Aha1 complex in PC3-MM2 cells

ACS Chemical Biology

Volumn 10, Issue 2, 2015, Pages 577-590

  Ghosh, Suman ^a   Shinogle, Heather E ^a   Garg, Gaurav ^a   Vielhauer, George A ^b   Holzbeierlein, Jeffrey M ^b   Dobrowsky, Rick T ^a   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDE; AHA1 PROTEIN; ANTIMETASTATIC AGENT; BENZAMIDE; CHAPERONE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; HEAT SHOCK PROTEIN 90ALPHA; KU 174; NOVOBIOCIN; RAB PROTEIN; RAC1 PROTEIN; UNCLASSIFIED DRUG; AHSA1 PROTEIN, HUMAN; HSP90ALPHA PROTEIN, HUMAN; ISOPROTEIN; PROTEIN BINDING;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; DRUG PROTEIN BINDING; GENE DISRUPTION; GENE SILENCING; HUMAN; HUMAN CELL; METASTASIS INHIBITION; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SECRETORY VESICLE; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL MOTION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROTEIN FOLDING;

CELL LINE; CELL MOVEMENT; GENE EXPRESSION REGULATION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; NOVOBIOCIN; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN ISOFORMS;

EID: 84923382589     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb5008713     Document Type: Article

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