-
1
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
El-Serag, H. B. & Rudolph, K. L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132, 2557-2576 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
2
-
-
7044260779
-
Environmental factors and risk for hepatocellular carcinoma
-
Yu, M. C. & Yuan, J. M. Environmental factors and risk for hepatocellular carcinoma. Gastroenterology 127, S72-78 (2004).
-
(2004)
Gastroenterology
, vol.127
, pp. S72-78
-
-
Yu, M.C.1
Yuan, J.M.2
-
3
-
-
84901826085
-
Toxicogenomics and cancer susceptibility: Advances with nextgeneration sequencing
-
Ning, B. et al. Toxicogenomics and cancer susceptibility: advances with nextgeneration sequencing. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 32, 121-158 (2014).
-
(2014)
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev
, vol.32
, pp. 121-158
-
-
Ning, B.1
-
4
-
-
0031035007
-
Polymorphisms in drug-metabolizing enzymes: What is their clinical relevance and why do they exist?
-
Nebert, D. W. Polymorphisms in drug-metabolizing enzymes: what is their clinical relevance and why do they exist? Am J Hum Genet 60, 265-271 (1997).
-
(1997)
Am J Hum Genet
, vol.60
, pp. 265-271
-
-
Nebert, D.W.1
-
5
-
-
0033984936
-
Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers
-
Bartsch, H. et al. Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. Cancer Epidemiol Biomarkers Prev 9, 3-28 (2000).
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 3-28
-
-
Bartsch, H.1
-
6
-
-
0029963622
-
Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer
-
Nebert, D. W., McKinnon, R. A. & Puga, A. Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer. DNA Cell Biol 15, 273-280 (1996).
-
(1996)
DNA Cell Biol
, vol.15
, pp. 273-280
-
-
Nebert, D.W.1
McKinnon, R.A.2
Puga, A.3
-
7
-
-
0037431433
-
CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer
-
Silvestri, L. et al. CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer. Int J Cancer 104, 310-317 (2003).
-
(2003)
Int J Cancer
, vol.104
, pp. 310-317
-
-
Silvestri, L.1
-
8
-
-
0031913767
-
Cytochrome P4502A6 (CYP2A6) expression in human hepatocellular carcinoma
-
Raunio, H. et al. Cytochrome P4502A6 (CYP2A6) expression in human hepatocellular carcinoma. Hepatology 27, 427-432 (1998).
-
(1998)
Hepatology
, vol.27
, pp. 427-432
-
-
Raunio, H.1
-
9
-
-
24344486850
-
Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma
-
Tsunedomi, R. et al. Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma. Int J Oncol 27, 661-667 (2005).
-
(2005)
Int J Oncol
, vol.27
, pp. 661-667
-
-
Tsunedomi, R.1
-
10
-
-
0035910064
-
Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver
-
Xu, X. R. et al. Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. Proc Natl Acad Sci U S A 98, 15089-15094 (2001).
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 15089-15094
-
-
Xu, X.R.1
-
11
-
-
33845267470
-
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
-
Nebert, D. W. & Dalton, T. P. The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis. Nat Rev Cancer 6, 947-960 (2006).
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 947-960
-
-
Nebert, D.W.1
Dalton, T.P.2
-
12
-
-
0028590127
-
Biochemistry and molecular biology of the human CYP2C subfamily
-
Goldstein, J. A. & de Morais, S. M. Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 4, 285-299 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 285-299
-
-
Goldstein, J.A.1
De Morais, S.M.2
-
13
-
-
0031841377
-
Cytochrome P4502C9: An enzyme of major importance in human drug metabolism
-
Miners, J. O. & Birkett, D. J. Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. Br J Clin Pharmacol 45, 525-538 (1998).
-
(1998)
Br J Clin Pharmacol
, vol.45
, pp. 525-538
-
-
Miners, J.O.1
Birkett, D.J.2
-
14
-
-
0035985214
-
Gene expression patterns in human liver cancers
-
Chen, X. et al. Gene expression patterns in human liver cancers. Mol Biol Cell 13, 1929-1939 (2002).
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1929-1939
-
-
Chen, X.1
-
15
-
-
1242336973
-
Cancer-associated molecular signature in the tissue samples of patients with cirrhosis
-
Kim, J. W. et al. Cancer-associated molecular signature in the tissue samples of patients with cirrhosis. Hepatology 39, 518-527 (2004).
-
(2004)
Hepatology
, vol.39
, pp. 518-527
-
-
Kim, J.W.1
-
16
-
-
0035266345
-
Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: Identification of genes involved in viral carcinogenesis and tumor progression
-
Okabe, H. et al. Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res 61, 2129-2137 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 2129-2137
-
-
Okabe, H.1
-
17
-
-
0037442702
-
Identification of novel tumor markers in hepatitis C virusassociated hepatocellular carcinoma
-
Smith, M. W. et al. Identification of novel tumor markers in hepatitis C virusassociated hepatocellular carcinoma. Cancer Res 63, 859-864 (2003).
-
(2003)
Cancer Res
, vol.63
, pp. 859-864
-
-
Smith, M.W.1
-
19
-
-
84872259086
-
MicroRNAs as mediators of drug toxicity
-
Yokoi, T. & Nakajima, M. microRNAs as mediators of drug toxicity. Annu Rev Pharmacol Toxicol 53, 377-400 (2013).
-
(2013)
Annu Rev Pharmacol Toxicol
, vol.53
, pp. 377-400
-
-
Yokoi, T.1
Nakajima, M.2
-
20
-
-
33749487425
-
MicroRNA regulates the expression of human cytochrome P450 1B1
-
Tsuchiya, Y., Nakajima, M., Takagi, S., Taniya, T. & Yokoi, T. MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res 66, 9090-9098 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 9090-9098
-
-
Tsuchiya, Y.1
Nakajima, M.2
Takagi, S.3
Taniya, T.4
Yokoi, T.5
-
21
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin, G. A. & Croce, C. M. MicroRNA signatures in human cancers. Nat Rev Cancer 6, 857-866 (2006).
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
22
-
-
84860745157
-
MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function
-
Donzelli, S. et al. MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function. Cell Death Differ 19, 1038-1048 (2012).
-
(2012)
Cell Death Differ
, vol.19
, pp. 1038-1048
-
-
Donzelli, S.1
-
23
-
-
56449126945
-
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
-
Godlewski, J. et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 68, 9125-9130 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 9125-9130
-
-
Godlewski, J.1
-
24
-
-
76649106744
-
Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer
-
Khan, A. P. et al. Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer. Mol Cell Proteomics 9, 298-312 (2010).
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 298-312
-
-
Khan, A.P.1
-
25
-
-
77954315239
-
Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
-
Gao, W. et al. Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed Pharmacother 64, 399-408 (2010).
-
(2010)
Biomed Pharmacother
, vol.64
, pp. 399-408
-
-
Gao, W.1
-
26
-
-
79953696225
-
MiR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS
-
Xu, B. et al. miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS. Mol Cell Biochem 350, 207-213 (2011).
-
(2011)
Mol Cell Biochem
, vol.350
, pp. 207-213
-
-
Xu, B.1
-
27
-
-
29944444269
-
Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells
-
Aninat, C. et al. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells. Drug Metab Dispos 34, 75-83 (2006).
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 75-83
-
-
Aninat, C.1
-
28
-
-
84875886326
-
Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN-AKT pathway
-
Palumbo, T. et al. Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN-AKT pathway. Oncogene 32, 1651-1659 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 1651-1659
-
-
Palumbo, T.1
-
29
-
-
84890442900
-
Sex differences in the expression of drug-metabolizing and transporter genes in human liver
-
Yang, L. et al. Sex differences in the expression of drug-metabolizing and transporter genes in human liver. JDrug Metab Toxicol 3,119; DOI:10.4172/2157-7609.1000119 (2012).
-
(2012)
JDrug Metab Toxicol
, vol.3
, pp. 119
-
-
Yang, L.1
-
30
-
-
40049097690
-
Systematic and simultaneous gene profiling of 84 drug-metabolizing genes in primary human hepatocytes
-
Ning, B. et al. Systematic and simultaneous gene profiling of 84 drug-metabolizing genes in primary human hepatocytes. J Biomol Screen 13, 194-201 (2008).
-
(2008)
J Biomol Screen
, vol.13
, pp. 194-201
-
-
Ning, B.1
-
31
-
-
84876541448
-
Gene expression variability in human hepatic drug metabolizing enzymes and transporters
-
Yang, L. et al. Gene expression variability in human hepatic drug metabolizing enzymes and transporters. PLoS One 8, e60368; DOI:10.1371/journal.pone.0060368 (2013).
-
(2013)
PLoS One
, vol.8
, pp. e60368
-
-
Yang, L.1
-
32
-
-
0028797624
-
Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes
-
Bauer, E. et al. Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes. Chem Res Toxicol 8, 136-142 (1995).
-
(1995)
Chem Res Toxicol
, vol.8
, pp. 136-142
-
-
Bauer, E.1
-
33
-
-
0033018006
-
Analyses of bronchial bulky DNA adduct levels and CYP2C9, GSTP1 and NQO1 genotypes in a Hungarian study population with pulmonary diseases
-
Ozawa, S. et al. Analyses of bronchial bulky DNA adduct levels and CYP2C9, GSTP1 and NQO1 genotypes in a Hungarian study population with pulmonary diseases. Carcinogenesis 20, 991-995 (1999).
-
(1999)
Carcinogenesis
, vol.20
, pp. 991-995
-
-
Ozawa, S.1
-
34
-
-
0027937066
-
The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol
-
Shou, M., Korzekwa, K. R., Crespi, C. L., Gonzalez, F. J. & Gelboin, H. V. The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol. Mol Carcinog 10, 159-168 (1994).
-
(1994)
Mol Carcinog
, vol.10
, pp. 159-168
-
-
Shou, M.1
Korzekwa, K.R.2
Crespi, C.L.3
Gonzalez, F.J.4
Gelboin, H.V.5
-
35
-
-
0034909331
-
Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk
-
Martinez, C. et al. Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk. Carcinogenesis 22, 1323-1326 (2001).
-
(2001)
Carcinogenesis
, vol.22
, pp. 1323-1326
-
-
Martinez, C.1
-
36
-
-
3543004770
-
A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma
-
Chan, A. T., Tranah, G. J., Giovannucci, E. L., Hunter, D. J. & Fuchs, C. S. A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma. Clin Gastroenterol Hepatol 2, 704-712 (2004).
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 704-712
-
-
Chan, A.T.1
Tranah, G.J.2
Giovannucci, E.L.3
Hunter, D.J.4
Fuchs, C.S.5
-
37
-
-
0030773244
-
Lung cancer risk in relation to the CYP2C9 genetic polymorphism among Caucasians in Los Angeles County
-
London, S. J., Sullivan-Klose, T., Daly, A. K. & Idle, J. R. Lung cancer risk in relation to the CYP2C9 genetic polymorphism among Caucasians in Los Angeles County. Pharmacogenetics 7, 401-404 (1997).
-
(1997)
Pharmacogenetics
, vol.7
, pp. 401-404
-
-
London, S.J.1
Sullivan-Klose, T.2
Daly, A.K.3
Idle, J.R.4
-
38
-
-
79952791439
-
Practical aspects ofmicroRNA target prediction
-
Witkos, T. M., Koscianska, E. & Krzyzosiak, W. J. Practical Aspects ofmicroRNA Target Prediction. Curr Mol Med 11, 93-109 (2011).
-
(2011)
Curr Mol Med
, vol.11
, pp. 93-109
-
-
Witkos, T.M.1
Koscianska, E.2
Krzyzosiak, W.J.3
-
39
-
-
84887139031
-
MiR-128 and its target genes in tumorigenesis andmetastasis
-
Li, M. et al. miR-128 and its target genes in tumorigenesis andmetastasis. Exp Cell Res 319, 3059-3064 (2013).
-
(2013)
Exp Cell Res
, vol.319
, pp. 3059-3064
-
-
Li, M.1
-
40
-
-
84866287777
-
Aberrant microRNA expression in human cervical carcinomas
-
Rao, Q. et al. Aberrant microRNA expression in human cervical carcinomas. Med Oncol 29, 1242-1248 (2012).
-
(2012)
Med Oncol
, vol.29
, pp. 1242-1248
-
-
Rao, Q.1
-
41
-
-
84880699782
-
MicroRNA expression profiles in the progression of prostate cancer-from high-grade prostate intraepithelial neoplasia to metastasis
-
Leite, K. R. et al. MicroRNA expression profiles in the progression of prostate cancer-from high-grade prostate intraepithelial neoplasia to metastasis. Urol Oncol 31, 796-801 (2013).
-
(2013)
Urol Oncol
, vol.31
, pp. 796-801
-
-
Leite, K.R.1
-
42
-
-
79951922704
-
Similarities and differences in the expression of drug metabolizing enzymes between human hepatic cell lines and primary human hepatocytes
-
Guo, L. et al. Similarities and differences in the expression of drug metabolizing enzymes between human hepatic cell lines and primary human hepatocytes. Drug Metab Dispos 39, 528-538 (2010).
-
(2010)
Drug Metab Dispos
, vol.39
, pp. 528-538
-
-
Guo, L.1
-
43
-
-
4644237189
-
Fast and effective prediction of microRNA/target duplexes
-
Rehmsmeier, M., Steffen, P., Hochsmann, M. & Giegerich, R. Fast and effective prediction of microRNA/target duplexes. RNA 10, 1507-1517 (2004).
-
(2004)
RNA
, vol.10
, pp. 1507-1517
-
-
Rehmsmeier, M.1
Steffen, P.2
Hochsmann, M.3
Giegerich, R.4
-
44
-
-
84855379048
-
Copy number variation at 6q13 functions as a long-range regulator and is associated with pancreatic cancer risk
-
Huang, L. et al. Copy number variation at 6q13 functions as a long-range regulator and is associated with pancreatic cancer risk. Carcinogenesis 33, 94-100 (2012).
-
(2012)
Carcinogenesis
, vol.33
, pp. 94-100
-
-
Huang, L.1
-
45
-
-
78549246589
-
Functional genetic variants in the 3′-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity
-
Yu, X. et al. Functional genetic variants in the 3′-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity. Toxicol Sci 118, 391-403 (2010).
-
(2010)
Toxicol Sci
, vol.118
, pp. 391-403
-
-
Yu, X.1
|