메뉴 건너뛰기




Volumn 6, Issue 1, 2014, Pages

Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples

Author keywords

Decitabine; FHIT; FUS1; LINE 1 methylation; PTEN; Tumor suppressor genes; WWOX

Indexed keywords

DECITABINE; DNA; FRAGILE HISTIDINE TRIAD PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 84923367056     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/1868-7083-6-13     Document Type: Article
Times cited : (8)

References (51)
  • 2
    • 34547799171 scopus 로고    scopus 로고
    • DNA methyltransferases as targets for cancer therapy
    • Ghoshal K, Bai S: DNA methyltransferases as targets for cancer therapy. Drugs Today (Barc) 2007, 43: 395-422.
    • (2007) Drugs Today (Barc) , vol.43 , pp. 395-422
    • Ghoshal, K.1    Bai, S.2
  • 4
    • 33846274591 scopus 로고    scopus 로고
    • Inhibition of breast cancer cell growth in vitro and in vivo: Effect of restoration of Wwox expression
    • Iliopoulos D, Fabbri M, Druck T, Qin HR, Han SY, Huebner K: Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression. Clin Cancer Res 2007, 13: 268-274.
    • (2007) Clin Cancer Res , vol.13 , pp. 268-274
    • Iliopoulos, D.1    Fabbri, M.2    Druck, T.3    Qin, H.R.4    Han, S.Y.5    Huebner, K.6
  • 9
    • 84901308117 scopus 로고    scopus 로고
    • Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors
    • Stewart DJ, Nunez MI, Jelinek J, Hong D, Gupta S, Issa JP, Wistuba II, Kurzrock R: Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors. Clin Epigenetics 2014, 6(1): 2.
    • (2014) Clin Epigenetics , vol.6 , Issue.1 , pp. 2
    • Stewart, D.J.1    Nunez, M.I.2    Jelinek, J.3    Hong, D.4    Gupta, S.5    Issa, J.P.6    Wistuba, I.I.7    Kurzrock, R.8
  • 10
    • 0346096759 scopus 로고    scopus 로고
    • Alteration of the fragile histidine triad gene early in carcinogenesis: An update
    • Ishii H, Ozawa K, Furukawa Y: Alteration of the fragile histidine triad gene early in carcinogenesis: an update. J Exp Ther Oncol 2003, 3: 291-296.
    • (2003) J Exp Ther Oncol , vol.3 , pp. 291-296
    • Ishii, H.1    Ozawa, K.2    Furukawa, Y.3
  • 12
    • 84872485839 scopus 로고    scopus 로고
    • Loss of heterozygosity and methylation of multiple tumor suppressor genes on chromosome 3 in hepatocellular carcinoma
    • Zhang X, Li HM, Liu Z, Zhou G, Zhang Q, Zhang T, Zhang J, Zhang C: Loss of heterozygosity and methylation of multiple tumor suppressor genes on chromosome 3 in hepatocellular carcinoma. J Gastroenterol 2013, 48: 132-143.
    • (2013) J Gastroenterol , vol.48 , pp. 132-143
    • Zhang, X.1    Li, H.M.2    Liu, Z.3    Zhou, G.4    Zhang, Q.5    Zhang, T.6    Zhang, J.7    Zhang, C.8
  • 13
    • 79551689151 scopus 로고    scopus 로고
    • Frequent hypermethylation of DAPK, RARbeta, MGMT, RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa
    • Paluszczak J, Misiak P, Wierzbicka M, Wozniak A, Baer-Dubowska W: Frequent hypermethylation of DAPK, RARbeta, MGMT, RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa. Oral Oncol 2011, 47: 104-107.
    • (2011) Oral Oncol , vol.47 , pp. 104-107
    • Paluszczak, J.1    Misiak, P.2    Wierzbicka, M.3    Wozniak, A.4    Baer-Dubowska, W.5
  • 15
    • 77949274045 scopus 로고    scopus 로고
    • Role of 5'-CpG island hypermethylation of the FHIT gene in cervical carcinoma
    • Ki KD, Lee SK, Tong SY, Lee JM, Song DH, Chi SG: Role of 5'-CpG island hypermethylation of the FHIT gene in cervical carcinoma. J Gynecol Oncol 2008, 19: 117-122.
    • (2008) J Gynecol Oncol , vol.19 , pp. 117-122
    • Ki, K.D.1    Lee, S.K.2    Tong, S.Y.3    Lee, J.M.4    Song, D.H.5    Chi, S.G.6
  • 19
    • 84876223729 scopus 로고    scopus 로고
    • The role of the WWOX gene in leukemia and its mechanisms of action
    • Cui Z, Lin D, Cheng F, Luo L, Kong L, Xu J, Hu J, Lan F: The role of the WWOX gene in leukemia and its mechanisms of action. Oncol Rep 2013, 29: 2154-2162.
    • (2013) Oncol Rep , vol.29 , pp. 2154-2162
    • Cui, Z.1    Lin, D.2    Cheng, F.3    Luo, L.4    Kong, L.5    Xu, J.6    Hu, J.7    Lan, F.8
  • 20
    • 84880513475 scopus 로고    scopus 로고
    • Common chromosomal fragile site FRA16D tumor suppressor WWOX gene expression and metabolic reprograming in cells
    • Dayan S, O’Keefe LV, Choo A, Richards RI: Common chromosomal fragile site FRA16D tumor suppressor WWOX gene expression and metabolic reprograming in cells. Genes Chromosomes Cancer 2013, 52: 823-831.
    • (2013) Genes Chromosomes Cancer , vol.52 , pp. 823-831
    • Dayan, S.1    O’Keefe, L.V.2    Choo, A.3    Richards, R.I.4
  • 21
    • 34347371806 scopus 로고    scopus 로고
    • WWOX in biological control and tumorigenesis
    • Aqeilan RI, Croce CM: WWOX in biological control and tumorigenesis. J Cell Physiol 2007, 212: 307-310.
    • (2007) J Cell Physiol , vol.212 , pp. 307-310
    • Aqeilan, R.I.1    Croce, C.M.2
  • 22
    • 33845900365 scopus 로고    scopus 로고
    • WWOX protein expression in normal human tissues
    • Nunez MI, Ludes-Meyers J, Aldaz CM: WWOX protein expression in normal human tissues. J Mol Histol 2006, 37: 115-125.
    • (2006) J Mol Histol , vol.37 , pp. 115-125
    • Nunez, M.I.1    Ludes-Meyers, J.2    Aldaz, C.M.3
  • 24
    • 84863836167 scopus 로고    scopus 로고
    • Cigarette smoking extract causes hypermethylation and inactivation of WWOX gene in T-24 human bladder cancer cells
    • Yang W, Cui S, Ma J, Lu Q, Kong C, Liu T, Sun Z: Cigarette smoking extract causes hypermethylation and inactivation of WWOX gene in T-24 human bladder cancer cells. Neoplasma 2012, 59: 216-223.
    • (2012) Neoplasma , vol.59 , pp. 216-223
    • Yang, W.1    Cui, S.2    Ma, J.3    Lu, Q.4    Kong, C.5    Liu, T.6    Sun, Z.7
  • 25
    • 84877249897 scopus 로고    scopus 로고
    • Decreased expression of WWOX in the development of esophageal squamous cell carcinoma
    • Guo W, Wang G, Dong Y, Guo Y, Kuang G, Dong Z: Decreased expression of WWOX in the development of esophageal squamous cell carcinoma. Mol Carcinog 2013, 52: 265-274.
    • (2013) Mol Carcinog , vol.52 , pp. 265-274
    • Guo, W.1    Wang, G.2    Dong, Y.3    Guo, Y.4    Kuang, G.5    Dong, Z.6
  • 27
    • 77954647657 scopus 로고    scopus 로고
    • WWOX gene may contribute to progression of non-small-cell lung cancer (NSCLC)
    • Baykara O, Demirkaya A, Kaynak K, Tanju S, Toker A, Buyru N: WWOX gene may contribute to progression of non-small-cell lung cancer (NSCLC). Tumour Biol 2010, 31: 315-320.
    • (2010) Tumour Biol , vol.31 , pp. 315-320
    • Baykara, O.1    Demirkaya, A.2    Kaynak, K.3    Tanju, S.4    Toker, A.5    Buyru, N.6
  • 28
    • 41749104248 scopus 로고    scopus 로고
    • Tumor suppressor FUS1 signaling pathway
    • Ji L, Roth JA: Tumor suppressor FUS1 signaling pathway. J Thorac Oncol 2008, 3: 327-330.
    • (2008) J Thorac Oncol , vol.3 , pp. 327-330
    • Ji, L.1    Roth, J.A.2
  • 30
    • 83255166586 scopus 로고    scopus 로고
    • Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines
    • da Costa PE, Cavalli LR, Rainho CA: Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines. Epigenetics 2011, 6: 1413-1424.
    • (2011) Epigenetics , vol.6 , pp. 1413-1424
    • Da Costa, P.E.1    Cavalli, L.R.2    Rainho, C.A.3
  • 31
    • 79953038262 scopus 로고    scopus 로고
    • PTEN loss in the continuum of common cancers, rare syndromes and mouse models
    • Hollander MC, Blumenthal GM, Dennis PA: PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat Rev Cancer 2011, 11: 289-301.
    • (2011) Nat Rev Cancer , vol.11 , pp. 289-301
    • Hollander, M.C.1    Blumenthal, G.M.2    Dennis, P.A.3
  • 34
    • 84858220893 scopus 로고    scopus 로고
    • Altered transcription and expression of PTEN in breast tumors: Is it regulated by hypermethylation?
    • Shetty PJ, Pasupuleti N, Chava S, Nasaruddin K, Hasan Q: Altered transcription and expression of PTEN in breast tumors: is it regulated by hypermethylation? Breast Dis 2011, 33: 27-33.
    • (2011) Breast Dis , vol.33 , pp. 27-33
    • Shetty, P.J.1    Pasupuleti, N.2    Chava, S.3    Nasaruddin, K.4    Hasan, Q.5
  • 35
    • 33748639077 scopus 로고    scopus 로고
    • Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data
    • Yang HJ, Liu VW, Wang Y, Tsang PC, Ngan HY: Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data. BMC Cancer 2006, 6: 212.
    • (2006) BMC Cancer , vol.6 , pp. 212
    • Yang, H.J.1    Liu, V.W.2    Wang, Y.3    Tsang, P.C.4    Ngan, H.Y.5
  • 39
    • 3042707323 scopus 로고    scopus 로고
    • Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis
    • Yu J, Ni M, Xu J, Zhang H, Gao B, Gu J, Chen J, Zhang L, Wu M, Zhen S, Zhu J: Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. BMC Cancer 2002, 2: 29.
    • (2002) BMC Cancer , vol.2 , pp. 29
    • Yu, J.1    Ni, M.2    Xu, J.3    Zhang, H.4    Gao, B.5    Gu, J.6    Chen, J.7    Zhang, L.8    Wu, M.9    Zhen, S.10    Zhu, J.11
  • 40
    • 1642474373 scopus 로고    scopus 로고
    • Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia
    • Tamura G: Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia. Histol Histopathol 2004, 19: 221-228.
    • (2004) Histol Histopathol , vol.19 , pp. 221-228
    • Tamura, G.1
  • 43
    • 77954121574 scopus 로고    scopus 로고
    • A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer
    • Fang F, Balch C, Schilder J, Breen T, Zhang S, Shen C, Li L, Kulesavage C, Snyder AJ, Nephew KP, Matei DE: A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer. Cancer 2010, 116: 4043-4053.
    • (2010) Cancer , vol.116 , pp. 4043-4053
    • Fang, F.1    Balch, C.2    Schilder, J.3    Breen, T.4    Zhang, S.5    Shen, C.6    Li, L.7    Kulesavage, C.8    Snyder, A.J.9    Nephew, K.P.10    Matei, D.E.11
  • 44
    • 79955937471 scopus 로고    scopus 로고
    • p53 gene therapy in combination with transcatheter arterial chemoembolization for HCC: One-year follow-up
    • Guan YS, Liu Y, He Q, Li X, Yang L, Hu Y, La Z: p53 gene therapy in combination with transcatheter arterial chemoembolization for HCC: one-year follow-up. World J Gastroenterol 2011, 17: 2143-2149.
    • (2011) World J Gastroenterol , vol.17 , pp. 2143-2149
    • Guan, Y.S.1    Liu, Y.2    He, Q.3    Li, X.4    Yang, L.5    Hu, Y.6    La, Z.7
  • 48
    • 78549260768 scopus 로고    scopus 로고
    • Association of 5'-CpG island hypermethylation of the FHIT gene with lung cancer in southern-central Chinese population
    • Li W, Deng J, Jiang P, Tang J: Association of 5'-CpG island hypermethylation of the FHIT gene with lung cancer in southern-central Chinese population. Cancer Biol Ther 2010, 10: 997-1000.
    • (2010) Cancer Biol Ther , vol.10 , pp. 997-1000
    • Li, W.1    Deng, J.2    Jiang, P.3    Tang, J.4
  • 49
    • 33646230046 scopus 로고    scopus 로고
    • Cohypermethylation of p16 and FHIT promoters as a prognostic factor of recurrence in surgically resected stage I non-small cell lung cancer
    • Kim JS, Kim JW, Han J, Shim YM, Park J, Kim DH: Cohypermethylation of p16 and FHIT promoters as a prognostic factor of recurrence in surgically resected stage I non-small cell lung cancer. Cancer Res 2006, 66: 4049-4054.
    • (2006) Cancer Res , vol.66 , pp. 4049-4054
    • Kim, J.S.1    Kim, J.W.2    Han, J.3    Shim, Y.M.4    Park, J.5    Kim, D.H.6
  • 50
    • 77956288615 scopus 로고    scopus 로고
    • Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation
    • Si J, Boumber YA, Shu J, Qin T, Ahmed S, He R, Jelinek J, Issa JP: Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation. Cancer Res 2010, 70: 6968-6977.
    • (2010) Cancer Res , vol.70 , pp. 6968-6977
    • Si, J.1    Boumber, Y.A.2    Shu, J.3    Qin, T.4    Ahmed, S.5    He, R.6    Jelinek, J.7    Issa, J.P.8
  • 51
    • 2342557977 scopus 로고    scopus 로고
    • A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
    • Yang AS, Estecio MR, Doshi K, Kondo Y, Tajara EH, Issa JP: A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004, 32: e38.
    • (2004) Nucleic Acids Res , vol.32 , pp. 38
    • Yang, A.S.1    Estecio, M.R.2    Doshi, K.3    Kondo, Y.4    Tajara, E.H.5    Issa, J.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.