Cigarette smoking extract causes hypermethylation and inactivation of WWOX gene in T-24 human bladder cancer cells

Neoplasma

Volumn 59, Issue 2, 2012, Pages 216-223

  Yang, W ^a   Cui, S ^a   Ma, J ^b   Lu, Q ^a   Kong, C ^a   Liu, T ^a   Sun, Z ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b HEBEI UNIVERSITY OF ENGINEERING   (China)

Author keywords

Bladder cancer; Cigarette smoking; DNA methylation; Immunohistochemistry; WWOX

Indexed keywords

CIGARETTE SMOKE; DNA METHYLTRANSFERASE 1; MESSENGER RNA; OXIDOREDUCTASE; TUMOR SUPPRESSOR PROTEIN; WWOX PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BLADDER CANCER; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOKING; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; WW DOMAIN CONTAINING OXIDOREDUCTASE GENE; BLADDER; BLADDER TUMOR; CASE CONTROL STUDY; COMPARATIVE STUDY; DRUG EFFECT; ENZYME IMMUNOASSAY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PROGNOSIS; PROMOTER REGION; TRANSITIONAL CELL CARCINOMA; TUMOR CELL CULTURE;

BLOTTING, WESTERN; CARCINOMA, TRANSITIONAL CELL; CASE-CONTROL STUDIES; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; OXIDOREDUCTASES; PROGNOSIS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SMOKING; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 84863836167     PISSN: 00282685     EISSN: 13384317     Source Type: Journal    
DOI: 10.4149/neo_2012_028     Document Type: Article

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