Mucosal microbiome in patients with recurrent aphthous stomatitis

Journal of Dental Research

Volumn 94, Issue , 2015, Pages 87S-94S

  Hijazi, K ^a   Lowe, T ^b   Meharg, C ^c   Berry, S H ^a   Foley, J ^a,d   Hold, G L ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b ABERDEEN ROYAL INFIRMARY   (United Kingdom)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^d EDINBURGH DENTAL INSTITUTE   (United Kingdom)

Author keywords

chronic disease; high throughput DNA sequencing; host pathogen relations; microbiota; oral mucosa; oral ulcer

Indexed keywords

ACIDAMINOCOCCACEAE; ADOLESCENT; ADULT; APHTHOUS STOMATITIS; BACTERIA; BACTERIAL PHENOMENA AND FUNCTIONS; BACTEROIDACEAE; CASE CONTROL STUDY; CLASSIFICATION; COMPARATIVE STUDY; FEMALE; GRAM NEGATIVE BACTERIUM; HIGH THROUGHPUT SEQUENCING; HUMAN; MALE; MICROBIOLOGY; MICROFLORA; MIDDLE AGED; MOUTH MUCOSA; PORPHYROMONAS; PROTEOBACTERIA; RECURRENT DISEASE; STREPTOCOCCACEAE; YOUNG ADULT;

ADOLESCENT; ADULT; BACTERIA; BACTERIAL PROCESSES; BACTEROIDACEAE; CASE-CONTROL STUDIES; FEMALE; GRAM-NEGATIVE BACTERIA; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MICROBIOTA; MIDDLE AGED; MOUTH MUCOSA; PORPHYROMONAS; PROTEOBACTERIA; RECURRENCE; STOMATITIS, APHTHOUS; STREPTOCOCCACEAE; VEILLONELLACEAE; YOUNG ADULT;

EID: 84923353169     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034514565458     Document Type: Article

References (34)

1. Al-Omiri MK, Karasneh J, Alhijawi MM, Zwiri AM, Scully C, Lynch E. Recurrent aphthous stomatitis (RAS): a preliminary within-subject study of quality of life, oral health impacts and personality profiles. J Oral Pathol Med. 2014 2014 ;:
2. Altenburg A, Abdel-Naser MB, Seeber H, Abdallah M, Zouboulis CC. Practical aspects of management of recurrent aphthous stomatitis. J Eur Acad Dermatol Venereol. 2007 ; 21 (8). 1019-1026
3. Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, Fierer N, Peña AG, Goodrich JK, Gordon JI, et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods. 2010 ; 7 (5). 335-336
4. Challacombe SJ, Scully C, Keevil B, Lehner T. Serum ferritin in recurrent oral ulceration. J Oral Pathol. 1983 ; 12 (4). 290-299
5. Colombo AV, Barbosa GM, Higashi D, di Micheli G, Rodrigues PH, Simionato MR. Quantitative detection of Staphylococcus aureus, Enterococcus faecalis and Pseudomonas aeruginosa in human oral epithelial cells from subjects with periodontitis and periodontal health. J Med Microbiol. 2013 ; 62 (Pt 10). 1592-1600
6. Department of Health and the British Association for the Study of Community Dentistry. 2009. Delivering better oral health: an evidence-based toolkit for prevention [accessed 2014 December 3]. http://www.oralhealthplatform.eu/sites/default/files/field/document/NHS-Delivering%20Better%20Oral%20health.pdf. 2nd ed. Sec 4.
7. Dewhirst FE, Chen T, Izard J, Paster BJ, Tanner AC, Yu WH, Lakshmanan A, Wade WG. The human oral microbiome. J Bacteriol. 2010 ; 192 (19). 5002-5017
8. Gallo C, Barros F, Sugaya N, Nunes F, Borra R. Differential expression of toll-like receptor mRNAs in recurrent aphthous ulceration. J Oral Pathol Med. 2012 ; 41 (1). 80-85
9. Ghannoum MA, Jurevic RJ, Mukherjee PK, Cui F, Sikaroodi M, Naqvi A, Gillevet PM. Characterization of the oral fungal microbiome (mycobiome) in healthy individuals. PLoS Pathog. 2010 ; 6 (1). e1000713
10. Hansen R, Russell RK, Reiff C, Louis P, McIntosh F, Berry SH, Mukhopadhya I, Bisset WM, Barclay AR, Bishop J, et al. Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis. Am J Gastroenterol. 2012 ; 107 (12). 1913-1922
11. Hasan A, Childerstone A, Pervin K, Shinnick T, Mizushima Y, Van der Zee R, Vaughan R, Lehner T. Recognition of a unique peptide epitope of the mycobacterial and human heat shock protein 65-60 antigen by T cells of patients with recurrent oral ulcers. Clin Exp Immunol. 1995 ; 99 (3). 392-397
12. Hietanen J, Hayrinen-Immonen R, Al-Samadi A, Trokovic N, Koskenpato K, Konttinen YT. Recurrent aphthous ulcers: a Toll-like receptor-mediated disease?. J Oral Pathol Med. 2012 ; 41 (2). 158-164
13. Hold GL, Smith EA, Rappé MS, Maas EW, Moore ER, Stroempl C, Stephen JR, Prosser JI, Birkbeck TH, Gallacher S. Characterisation of bacterial communities associated with toxic and non-toxic dinoflagellates: Alexandrium spp. and Scrippsiella trochoidea. FEMS Microbiology Ecology. 2001 ; 37 (2). 161-173
14. Jorth P, Turner KH, Gumus P, Nizam N, Buduneli N, Whiteley M. Metatranscriptomics of the human oral microbiome during health and disease. MBio. 2014 ; 5 (2). e01012 - e01014
15. Jurge S, Kuffer R, Scully C, Porter SR. Mucosal disease series: number VI. Recurrent aphthous stomatitis. Oral Dis. 2006 ; 12 (1). 1-21
16. Kumar PS, Griffen AL, Moeschberger ML, Leys EJ. Identification of candidate periodontal pathogens and beneficial species by quantitative 16S clonal analysis. J Clin Microbiol. 2005 ; 43 (8). 3944-3955
17. Liu B, Faller LL, Klitgord N, Mazumdar V, Ghodsi M, Sommer DD, Gibbons TR, Treangen TJ, Chang YC, Li S, et al. Deep sequencing of the oral microbiome reveals signatures of periodontal disease. PLoS One. 2012 ; 7 (6). e37919
18. Lozupone C, Hamady M, Knight R. UniFrac: an online tool for comparing microbial community diversity in a phylogenetic context. BMC Bioinformatics. 2006 ; 7: 371
19. Maekawa T, Krauss JL, Abe T, Jotwani R, Triantafilou M, Triantafilou K, Hashim A, Hoch S, Curtis MA, Nussbaum G, et al. Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis. Cell Host Microbe. 2014 ; 15 (6). 768-778
20. Mansour-Ghanaei F, Asmar M, Bagherzadeh AH, Ekbataninezhad S. Helicobacter pylori infection in oral lesions of patients with recurrent aphthous stomatitis. Med Sci Monit. 2005 ; 11 (12). CR576 - CR579
21. Marchini L, Campos MS, Silva AM, Paulino LC, Nobrega FG. Bacterial diversity in aphthous ulcers. Oral Microbiol Immunol. 2007 ; 22 (4). 225-231
22. Miyamoto NT, Borra RC, Abreu M, Weckx LL, Franco M. Immune-expression of HSP27 and IL-10 in recurrent aphthous ulceration. J Oral Pathol Med. 2008 ; 37 (8). 462-467
23. Mysak J, Podzimek S, Sommerova P, Lyuya-Mi Y, Bartova J, Janatova T, Prochazkova J, Duskova J. Porphyromonas gingivalis: major periodontopathic pathogen overview. J Immunol Res. 2014 ; 2014: 476068
24. Petersen C, Round JL. Defining dysbiosis and its influence on host immunity and disease. Cell Microbiol. 2014 ; 16 (7). 1024-1033
25. Pradeep K, Kuttappa MA, Prasana KR. Probiotics and oral health: an update. SADJ. 2014 ; 69 (1). 20-24
26. Riggio MP, Lennon A, Wray D. Detection of Helicobacter pylori DNA in recurrent aphthous stomatitis tissue by PCR. J Oral Pathol Med. 2000 ; 29 (10). 507-513
27. Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol. 2009 ; 9 (5). 313-323
28. Sheikh S, Gupta D, Pallagatti S, Singla I, Gupta R, Goel V. Role of topical drugs in treatment of oral mucosal diseases: a literature review. N Y State Dent J. 2013 ; 79 (6). 58-64
29. Slebioda Z, Szponar E, Kowalska A. Recurrent aphthous stomatitis: genetic aspects of etiology. Postepy Dermatol Alergol. 2013 ; 30 (2). 96-102
30. Sun A, Chen HM, Cheng SJ, Wang YP, Chang JY, Wu YC, Chiang CP. Significant association of deficiencies of hemoglobin, iron, vitamin B12, and folic acid and high homocysteine level with recurrent aphthous stomatitis. J Oral Pathol Med. 2014 2014 ;:
31. Tappuni AR, Kovacevic T, Shirlaw PJ, Challacombe SJ. Clinical assessment of disease severity in recurrent aphthous stomatitis. J Oral Pathol Med. 2013 ; 42 (8). 635-641
32. Taylor LJ, Bagg J, Walker DM, Peters TJ. Increased production of tumour necrosis factor by peripheral blood leukocytes in patients with recurrent oral aphthous ulceration. J Oral Pathol Med. 1992 ; 21 (1). 21-25
33. Thomson JM, Hansen R, Berry SH, Hope ME, Murray GI, Mukhopadhya I, McLean MH, Shen Z, Fox JG, El-Omar E, et al. Enterohepatic helicobacter in ulcerative colitis: potential pathogenic entities?. PLoS One. 2011 ; 6 (2). e17184
34. Zoetendal EG, Akkermans AD, De Vos WM. Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol. 1998 ; 64 (10). 3854-3859