Recurrent aphthous stomatitis: Genetic aspects of etiology

Postepy Dermatologii i Alergologii

Volumn 30, Issue 2, 2013, Pages 96-102

  Slebioda, Zuzanna ^a   Szponar, Elzbieta ^a   Kowalska, Anna ^b  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b INSTITUTE OF HUMAN GENETICS   (Poland)

Author keywords

Etiology; Genetic background; Recurrent aphthous stomatitis

Indexed keywords

CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HLA B35 ANTIGEN; HLA B51 ANTIGEN; HLA DR4 ANTIGEN; HLA DR5 ANTIGEN; HLA DR7 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; SEROTONIN RECEPTOR;

ALLELE; APHTHOUS STOMATITIS; ARTICLE; BEHCET DISEASE; CLINICAL FEATURE; DEPRESSION; DISEASE SEVERITY; DNA POLYMORPHISM; FAMILY HISTORY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HUMAN; INHERITANCE; SMOOTH MUSCLE RELAXATION; STRESS; VASODILATATION;

EID: 84878463574     PISSN: 1642395X     EISSN: None     Source Type: Journal    
DOI: 10.5114/pdia.2013.34158     Document Type: Article

References (55)

1. Natah SS, Konttinen YT, Enattah NS, et al. Recurrent aphthous ulcers today: a review of growing knowledge. Int J Oral Maxillofac Surg 2004; 33: 221-34.
2. Scully C, Gorsky M, Lozada-Nur F. The diagnosis and management of recurrent aphthous stomatitis: a consensus approach. J Am Dent Assoc 2003; 134: 200-7.
3. Sook-Bin W, Sonis ST. Recurrent aphthous ulcers: a review of diagnosis and treatment. J Am Dent Assoc 1996; 127: 1202-13.
4. McCullough MJ, Abdel-Hafeth S, Scully C. Recurrent aphthous stomatitis revisited: clinical features, associations, and new association with infant feeding practices? J Oral Pathol Med 2007; 36: 615-20.
5. von Mikulicz J, Kümmel W. Die Krankheiten des Mundes. 3 ed. Gustav Fischer, Jena 1912.
6. Kuczkowski J, Stankiewicz C, Kopacz A, et al. Jan Mikulicz-Radecki (1850-1905): pioneer of ednoscopy and burgery of the sinuses, throat and digestive tract. World J Surg 2004; 28: 1063-7.
7. Scully C, Porter S. Oral mucosal disease: recurrent aphthous stomatitis. Br J Oral Maxillofac Surg 2008; 46: 198-206.
8. Rogers III RS. Recurrent aphthous stomatitis: clinical characteristics and associated systemic disorders. Seminars in Cutaneous Medicine and Surgery 1997; 16: 278-83.
9. Field EA, Allan RB. Oral ulceration: aetiopathogenesis, clinical diagnosis and management in the gastrointestinal clinic. Aliment Pharmacol Ther 2003; 18: 949-62.
10. Jenerowicz D, Silny W, Danczak-Pazdrowska A, et al. Environmental factors and allergic diseases. Ann Agric Environ Med 2012; 19: 475-81.
11. Baelum J, Larsen P, Doekes G, Sigsgaard T. Health effects of selected microbiological control agents. A 3-year follow-up study. Ann Agric Environ Med 2012; 19: 631-6.
12. Akman A, Sallakci N, Coskun M, et al. TNF-alpha gene 1031 T/C polymorphism in Turkish patients with Behçet's disease. Br J Dermatol 2006; 155: 350-6.
13. Natah SS, Häyrinen-Immonen R, Hietanen J, et al. Immunolocalizoation of tumor necrosis factor-alpha expressing cells in recurrent aphthous ulcer lesions (RAU). J Oral Pathol Med 2000; 29: 19-25.
14. Chattopadhyay A, Chatterjee S. Risk indicators for recurrent aphthous ulcers among adults in the US. Community Dent Oral Epidemiol 2007; 35: 152-9.
15. Lewkowicz N, Banasik M, Tchórzewski H, et al. Predominance of production of Th1 type cytokines in recurrent aphthous ulceration. Dent Med Probl 2004; 42: 655-60.
16. Wardhana, Datau EA. Recurrent aphthous stomatitis caused by food allergy. Acta Med Indones-Indones J Intern Med 2010; 42: 236-40.
17. Shashy RG, Ridley MB. Aphthous ulcers: a difficult clinical entity. Am J Otolaryngol 2000; 21: 389-93.
18. Sun A, Rhong-Phong H, Chien-Ts C, et al. Some specific human leukocyte antigen (HLA)-DR/DQ haplotypes are more important than individual HLA-DR and -DQ phenotypes for the development of mucocutaneous type of Behçet's disease and for disease shift from recurrent aphthous stomatitis to mucocutaneous type of Behçet's disease. J Oral Pathol Med 2001; 30: 402-7.
19. Yilmaz S, Cimen KA. Familial Behçet's disease. Rheumatol Int 2010; 30: 1107-9.
20. Karasneh JA, Hajeer AH, Silman A, et al. Polymorphisms in endothelial nitric oxide synthase gene are associated with Behçet's disease. Rheumatology 2005; 44: 614-7.
21. Rivera-Hidalgo F, Shulman JD, Beach MM. The association of tobacco and other factors with recurrent aphthous stomatitis in an US adult population. Oral Dis 2004; 10: 335-45.
22. Chattopadhyay A, Chatterjee S. Risk indicators for recurrent aphthous ulcers among adults in the US. Community Dent Oral Epidemiol 2007; 35: 152-9.
23. Mumcu G, Cimilli H, Sur H, et al. Prevalence and distribution of oral lesions: a cross-sectional study in Turkey. Oral Dis 2005; 11: 81-7.
24. Reichart PA. Oral mucosal lesions in a representative crosssectional study of aging Germans. Community Dent Oral Epidemiol 2000; 28: 390-8.
25. Górska R. An epidemiological study of oral recurrent aphthous stomatitis (RAS) in children, adolescents and adults, aged 13-24, in Warsaw. Przeg Epid 1997; 51: 339-47.
26. Szponar E, Slebioda Z, Mania-Konsko A. Recurrent aphthous stomatitis in patients attending the Department of Oral Mucosa Diseases of Poznan Medical University on the basis of 10 years observation. Czas Stomatol 2006; 61: 488-94.
27. Aydemir S, Solak Tekin N, Aktunç E, et al. Celiac disease in patients having recurrent aphthous stomatitis. Turk J Gastroenterol 2004; 15: 192-5.
28. Miziara ID, Filho BCA, Weber R. AIDS and recurrent aphthous stomatitis. Rev Bras Otorrinolaringol 2005; 71: 517-20.
29. Miller MF, Garfunkel AA, Ram C, Ship II. Inheritance patterns in recurrent aphthous ulcers: twin and pedigree data. Oral Surg 1977; 43: 887-91.
30. Ship II. Inheritance of aphthous ulcers of the mouth. J Dent Res 1965; 5: 837-44.
31. Safadi RA. Prevalence of recurrent aphthous ulceration in Jordanian dental patients. BMC Oral Health 2009; 9: 31-6.
32. Kobayashi T, Sudo Y, Okamura S, et al. Monozygotic twins concordant for intestinal Behçet's disease. J Gastroenterol 2005; 40: 421-5.
33. Wozniak-Stolarska B, Sajewicz Z, Błachut K. Serum concentration of interleukin-10 in inflammatory bowel disease. Adv Clin Exp Med 2003; 12: 717-21.
34. Hall MA, McGlinn E, Coakley G, et al. Genetic polymorphism of IL-12 p40 gene in immune-mediated disease. Genes Immun 2000; 1: 219-24.
35. Buno IJ, Huff C, Weston WL, et al. Elevated levels of interferon gamma, tumor necrosis factor alpha, interleukins 2, 4, and 5, but not interleukin 10, are present in recurrent aphthous stomatitis. Arch Dermatol 1998; 134: 827-31.
36. Guimarães AL, Correia-Silva Jde F, Sá AR, et al. Investigation of functional gene polymorphisms IL-1beta, IL-6, IL-10 and TNF-alpha in individuals with recurrent aphthous stomatitis. Arch Oral Biol 2007; 52: 268-72.
37. Guimarães AL, Sá AR, Victória JM, et al. Association of IL-1beta polymorphism with recurrent aphthous stomatitis in Brazilian individuals. Oral Dis 2006; 12: 580-3.
38. Akman A, Ekinci NC, Karcaroglu H, et al. Relationship between periodontal findings and specific polymorphisms of interleukin- 1alpha and -1beta in Turkish patients with Behçet's disease. Arch Dermatol Res 2008; 300: 19-26.
39. Victoria JMN, Correia-Silva J, Pimenta FJ, et al. Serotonin transporter gene polymorphism (5-HTTLPR) in patients with recurrent aphthous stomatitis. J Oral Pathol Med 2005; 34: 494-7.
40. Salvarani C, Boiardi L, Casali B. Endothelial nitric oxide synthase gene polymorphisms in Behçet's disease. J Rheumatol 2002; 29: 535-40.
41. Kim JU, Chang HK, Lee SS, et al. Endothelial nitric oxide synthase gene polymorphisms in patients with Behçet's disease and rheumatic diseases with vasculitis. Ann Rheum Dis 2003; 62: 1083-7.
42. Bazrafshani MR, Hajeer AH, Ollier WER, Thornhill MH. IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS). Genes Immun 2002; 3: 302-5.
43. Bazrafshani MR, Hajeer AH, Ollier WER, Thornhill MH. Polymorphisms in the IL-10 and IL-12 gene cluster and risk of developing recurrent aphthous stomatitis. Oral Diseases 2003; 9: 287-91.
44. Borra RC, Andrade PM, Silva IDCG, et al. The Th1/Th2 im - mune-type response of the recurrent aphthous ulceration analyzed by cDNA microarray. J Oral Pathol Med 2004; 33: 140-6.
45. Oksel F, Keser G, Ozmen M, et al. Endothelial nitric oxide synthase gene Glu298Asp polymorphism is associated with Behçet's disease. Clin Exp Rheumatol 2006; 24: S79-82.
46. Wang XL, Wang J. Endothelial nitric oxide synthase gene sequence variations and vascular disease. Mol Gen Metab 2000; 70: 241-51.
47. Karasneh JA, Baszrafshani R, Thornhill M, Ollier WER. Endo - thelial nitric oxide synthase gene polymorphisms are not associated with recurrent aphthous stomatitis. Arch Oral Biol 2009; 54: 583-7.
48. Wilhelmsen NSW, Weber R, Monteiro F, et al. Correlation between histocompatibility antigens and recurrent aphthous stomatitis in the Brazilian population. Braz J Otorhinolaryngol 2009; 75: 426-31.
49. Özdemir M, Acar H, Deniz F, et al. HLA-B*51 in patients with recurrent aphthous stomatitis. Acta Derm Venereol 2009; 89: 202-3.
50. Challacombe SJ, Batchelor JR, Kennedy LA, Lehner T. HLA antigens in recurrent oral ulceration. Arch Dermatol 1977; 113: 1717-9.
51. Malmström M, Salo OP, Fyhrquist F. Immunogenetic markers and immune response in patients with recurrent oral ulceration. Int J Oral Surg 1983; 12: 23-30.
52. Lehner T, Welsh KI, Batchelor JR. The relationship of HLA-B and DR phenotypes to Behçet's syndrome, recurrent oral ulceration and the class of immune complexes. Immunology 1982; 47: 581-7.
53. Gallina G, Cumbo V, Messina P, Caruso C. HLA-A, B, C, DR, MT and MB antigens in recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1985; 59: 364-70.
54. Albanidou-Farmaki E, Kayavis IG, Polymenidis Z, Papanayotou P. HLA-A, B, C, and DR antigens in recurrent oral ulcers. Ann Dent 1988; 47: 5-8.
55. Albanidou-Farmaki E, Deligiannidis A, Markopoulos AK, et al. HLA haplotypes in recurrent aphthous stomatitis: a mode of inheritance? Int J Immunogenetics 2008; 35: 427-32.