Ultrastructural localization of adiponectin protein in vasculature of normal and atherosclerotic mice

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Mori, Takuya ^a   Koyama, Yoshihisa ^a   Maeda, Norikazu ^a   Nakamura, Yukiko ^a   Fujishima, Yuya ^a   Matsuda, Keisuke ^a   Funahashi, Tohru ^a   Shimada, Shoichi ^a   Shimomura, Iichiro ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CYTOKINE;

ANIMAL; AORTA; ATHEROSCLEROSIS; C57BL MOUSE; DEFICIENCY; ENDOTHELIUM CELL; INBORN ERROR OF METABOLISM; KNOCKOUT MOUSE; MALE; METABOLISM; MONOCYTE; MOUSE; SMOOTH MUSCLE FIBER; TRANSPORT VESICLE; VASCULAR ENDOTHELIUM;

ADIPONECTIN; ANIMALS; AORTA; ATHEROSCLEROSIS; CYTOKINES; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; MALE; METABOLISM, INBORN ERRORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; MYOCYTES, SMOOTH MUSCLE; TRANSPORT VESICLES;

EID: 84923312644     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep04895     Document Type: Article

References (55)

1. Aschoff, L. Observations concerning the relationship between cholesterol metabolism and vascular disease. Br. Med. J. 2, 1131-1134 (1932).
2. Kao, V. C. & Wissler, R. W. A study of the immunohistochemical localization of serum lipoproteins and other plasma proteins in human atherosclerotic lesions. Exp. Mol. Pathol. 4, 465-479 (1965).
3. Walton, K.W. & Williamson, N. Histological and immunofluorescent studies on the evolution of the human atheromatous plaque. J. Atheroscler. Res. 8, 599-624 (1968).
4. Ylä-Herttuala, S. et al. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J. Clin. Invest. 84, 1086-1095 (1989).
5. Hollander, W., Colombo, M. A., Kirkpatrick, B. & Paddock, J. Soluble proteins in the human atherosclerotic plaque. With spectral reference to immunoglobulins, C3-complement component, alpha 1-antitrypsin and alpha 2-macroglobulin. Atherosclerosis 34, 391-405 (1979).
6. Ross, R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801-809 (1993).
7. Ross, R. Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340, 115-126 (1999).
8. Libby, P. Inflammation in atherosclerosis. Nature 420, 868-874 (2002).
9. Matsuzawa, Y. Therapy Insight: adipocytokines in metabolic syndrome and related cardiovascular disease. Nat. Clin. Pract. Cardiovasc. Med. 3, 35-42 (2006).
10. Matsuzawa, Y., Funahashi, T., Kihara, S. & Shimomura, I. Adiponectin and metabolic syndrome. Arterioscler. Thromb. Vasc. Biol. 24, 29-33 (2004).
11. Okubo, K. et al. Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression. Nat. Genet. 2, 173-179 (1992).
12. Maeda, K. et al. Analysis of an expression profile of genes in the human adipose tissue. Gene 190, 227-235 (1997).
13. Maeda, K. et al. cDNAcloning and expression of a novel adipose specific collagenlike factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem. Biophys. Res. Commun. 221, 286-289 (1996).
14. Nakano, Y., Tobe, T., Choi-Miura, N. H., Mazda, T. & Tomita, M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J. Biochem. 120, 803-812 (1996).
15. Scherer, P. E., Williams, S., Fogliano, M., Baldini, G. & Lodish, H. F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J. Biol. Chem. 270, 26746-26749 (1995).
16. Hu, E., Liang, P. & Spiegelman, B. M. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J. Biol. Chem. 271, 10697-10703 (1996).
17. Arita, Y. et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem. Biophys. Res. Commun. 257, 79-83 (1999).
18. Kumada, M. et al. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler. Thromb. Vasc. Biol. 23, 85-89 (2003).
19. Pischon, T. et al. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 291, 1730-1737 (2004).
20. Hotta, K. et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler. Thromb. Vasc. Biol. 20, 1595-1599 (2000).
21. Lindsay, R. S. et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 360, 57-58 (2002).
22. Spranger, J. et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 361, 226-228 (2003).
23. Fruebis, J. et al. Proteolytic cleavage product of 30-kDa adipocyte complementrelated protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc. Natl. Acad. Sci. U. S. A. 98, 2005-2010 (2001).
24. Maeda, N. et al. Diet-induced insulin resistance in mice lacking adiponectin/ ACRP30. Nat. Med. 8, 731-737 (2002).
25. Kubota, N. et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J. Biol. Chem. 277, 25863-25866 (2002).
26. Okamoto, Y. et al. Adiponectin reduces atherosclerosis in apolipoprotein Edeficient mice. Circulation 106, 2767-2770 (2002).
27. Matsuda, M. et al. Role of adiponectin in preventing vascular stenosis. Themissing link of adipo-vascular axis. J. Biol. Chem. 277, 37487-37491 (2002).
28. Yokota, T. et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96, 1723-1732 (2000).
29. Kamada, Y. et al. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 125, 1796-1807 (2003).
30. Fujita, K. et al. Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha. Arterioscler. Thromb. Vasc. Biol. 28, 863-870 (2008).
31. Ouchi, N. et al. Novel modulator for endothelial adhesion molecules: adipocytederived plasma protein adiponectin. Circulation 100, 2473-2476 (1999).
32. Ouchi, N. et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 102, 1296-1301 (2000).
33. Ouchi, N. et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocytederived macrophages. Circulation 103, 1057-1063 (2001).
34. Arita, Y. et al. Adipocyte-derived plasma protein adiponectin acts as a plateletderived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation 105, 2893-2898 (2002).
35. Komura, N. et al. Adiponectin protein exists in aortic endothelial cells. PLoS One 8, e71271 (2013).
36. Ross, R. & Glomset, J. A. Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis. Science 180, 1332-1339 (1973).
37. Libby, P., Ridker, P. M. & Hansson, G. K. Progress and challenges in translating the biology of atherosclerosis. Nature 473, 317-325 (2011).
38. Weibel, E. R. & Palade, G. E. New cytoplasmic components in arterial endothelia. J. Cell. Biol. 23, 101-112 (1964).
39. Bogan, J. S. & Lodish, H. F. Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4. J. Cell. Biol. 146, 609-620 (1999).
40. Bose, A. et al. The v-SNARE Vti1a regulates insulin-stimulated glucose transport and Acrp30 secretion in 3T3-L1 adipocytes. J. Biol. Chem. 280, 36946-36951 (2005).
41. Wang, Z.V. et al. Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention. Mol. Cell. Biol. 27, 3716-3731 (2007).
42. Qiang, L., Wang, H. & Farmer, S. R. Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha. Mol. Cell. Biol. 27, 4698-4707 (2007).
43. Wang, Z. V. & Scherer, P. E. DsbA-L is a versatile player in adiponectin secretion. Proc. Natl. Acad. Sci. U. S. A. 105, 18077-18078 (2008).
44. Owens, G. K., Kumar, M. S. & Wamhoff, B. R. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol. Rev. 84, 767-801 (2004).
45. Ding, M. et al. Vascular smooth muscle cell-derived adiponectin: a paracrine regulator of contractile phenotype. J. Mol. Cell. Cardiol. 52, 474-484 (2012).
46. Wang, Y. et al. Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J. Biol. Chem. 280, 18341-18347 (2005).
47. Kumada, M. et al. Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation 109, 2046-2049 (2004).
48. Loppnow, H., Buerke, M., Werdan, K. & Rose-John, S. Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis. J. Cell. Mol. Med. 15, 484-500 (2011).
49. Ingersoll, M. A., Platt, A. M., Potteaux, S. & Randolph, G. J. Monocyte trafficking in acute and chronic inflammation. Trends. Immunol. 32, 470-477 (2011).
50. White, G. E., Iqbal, A. J. & Greaves, D. R. CC chemokine receptors and chronic inflammation-therapeutic opportunities and pharmacological challenges. Pharmacol. Rev. 65, 47-89 (2013).
51. Hug, C. et al. T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc. Natl. Acad. Sci. U. S. A. 101, 10308-10313 (2004).
52. Takemura, Y. et al. Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J. Clin. Invest. 117, 375-386 (2007).
53. Yamauchi, T. et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423, 762-769 (2003).
54. Okamoto, Y. et al. An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm. Metab. Res. 32, 47-50 (2000).
55. Koyama, Y., Nishida, T. & Tohyama, M. Establishment of an optimised protocol for a Golgi-electron microscopy method based on a Golgi-Cox staining procedure with a commercial kit. J. Neurosci. Methods. 218, 103-109 (2013).