-
1
-
-
78149483057
-
Triple-negative breast cancer
-
Foulkes, W. D., Smith, I. E. & Reis-Filho, J. S. Triple-negative breast cancer. N. Engl. J. Med. 363, 1938-1948 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1938-1948
-
-
Foulkes, W.D.1
Smith, I.E.2
Reis-Filho, J.S.3
-
2
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou, C. M. et al. Molecular portraits of human breast tumours. Nature 406, 747-752 (2000).
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
-
3
-
-
34547661993
-
Triple-negative breast cancer: Clinical features and patterns of recurrence
-
Dent, R. et al. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin. Cancer Res. 13, 4429-4434 (2007).
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 4429-4434
-
-
Dent, R.1
-
4
-
-
33644560281
-
Cancer stem cells: An old idea-a paradigm shift
-
discussion 1895-1886
-
Wicha, M. S., Liu, S. & Dontu, G. Cancer stem cells: an old idea-a paradigm shift. Cancer Res. 66, 1883-1890; discussion 1895-1886 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 1883-1890
-
-
Wicha, M.S.1
Liu, S.2
Dontu, G.3
-
5
-
-
56749114437
-
Breast cancer stem cells: Implications for therapy of breast cancer
-
Morrison, B. J., Schmidt, C. W., Lakhani, S. R., Reynolds, B. A. & Lopez, J. A. Breast cancer stem cells: implications for therapy of breast cancer. Breast Cancer Res. 10, 210 (2008).
-
(2008)
Breast Cancer Res.
, vol.10
, pp. 210
-
-
Morrison, B.J.1
Schmidt, C.W.2
Lakhani, S.R.3
Reynolds, B.A.4
Lopez, J.A.5
-
6
-
-
20144385807
-
CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation
-
Xin, H. et al. CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation. J. Biol. Chem. 280, 20842-20850 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20842-20850
-
-
Xin, H.1
-
7
-
-
33847222687
-
Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation
-
Kamynina, E., Kauppinen, K., Duan, F., Muakkassa, N. & Manor, D. Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation. Mol. Cell Biol. 27, 1809-1822 (2007).
-
(2007)
Mol. Cell Biol.
, vol.27
, pp. 1809-1822
-
-
Kamynina, E.1
Kauppinen, K.2
Duan, F.3
Muakkassa, N.4
Manor, D.5
-
8
-
-
28144439277
-
CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha
-
Fan, M., Park, A. & Nephew, K. P. CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha. Mol. Endocrinol. 19, 2901-2914 (2005).
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 2901-2914
-
-
Fan, M.1
Park, A.2
Nephew, K.P.3
-
9
-
-
61849088969
-
The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways
-
Kajiro, M. et al. The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways. Nat. Cell Biol. 11, 312-319 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 312-319
-
-
Kajiro, M.1
-
10
-
-
0017145975
-
Stereospecific, high affinity binding of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase
-
Poland, A., Glover, E. & Kende, A. S. Stereospecific, high affinity binding of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase. J. Biol. Chem. 251, 4936-4946 (1976).
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 4936-4946
-
-
Poland, A.1
Glover, E.2
Kende, A.S.3
-
11
-
-
0030888748
-
Aryl hydrocarbon receptor-mediated signal transduction
-
Rowlands, J. C. & Gustafsson, J. A. Aryl hydrocarbon receptor-mediated signal transduction. Crit. Rev. Toxicol. 27, 109-134 (1997).
-
(1997)
Crit. Rev. Toxicol.
, vol.27
, pp. 109-134
-
-
Rowlands, J.C.1
Gustafsson, J.A.2
-
12
-
-
0033602654
-
Estrogen and aryl hydrocarbon responsiveness of ECC-1 endometrial cancer cells
-
Castro-Rivera, E., Wormke, M. & Safe, S. Estrogen and aryl hydrocarbon responsiveness of ECC-1 endometrial cancer cells. Mol. Cell Endocrinol. 150, 11-21 (1999).
-
(1999)
Mol. Cell Endocrinol.
, vol.150
, pp. 11-21
-
-
Castro-Rivera, E.1
Wormke, M.2
Safe, S.3
-
13
-
-
0034176593
-
Estrogen and aryl hydrocarbon receptor expression and crosstalk in human Ishikawa endometrial cancer cells
-
Wormke, M., Castro-Rivera, E., Chen, I. & Safe, S. Estrogen and aryl hydrocarbon receptor expression and crosstalk in human Ishikawa endometrial cancer cells. J. Steroid Biochem. Mol. Biol. 72, 197-207 (2000).
-
(2000)
J. Steroid Biochem. Mol. Biol.
, vol.72
, pp. 197-207
-
-
Wormke, M.1
Castro-Rivera, E.2
Chen, I.3
Safe, S.4
-
14
-
-
1542269170
-
Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation
-
Morrow, D., Qin, C., Smith, R., 3rd & Safe, S. Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation. J. Steroid Biochem. Mol. Biol. 88, 27-36 (2004).
-
(2004)
J. Steroid Biochem. Mol. Biol.
, vol.88
, pp. 27-36
-
-
Morrow, D.1
Qin, C.2
Smith, R.3
Safe, S.4
-
15
-
-
0037026632
-
Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer
-
Koliopanos, A. et al. Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer. Oncogene 21, 6059-6070 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 6059-6070
-
-
Koliopanos, A.1
-
16
-
-
0034451228
-
Comparative effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on MCF-7, RL95-2, and LNCaP cells: Role of target steroid hormones in cellular responsiveness to CYP1A1 induction
-
Jana, N. R. et al. Comparative effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on MCF-7, RL95-2, and LNCaP cells: role of target steroid hormones in cellular responsiveness to CYP1A1 induction. Mol. Cell. Biol. Res. Commun. 4, 174-180 (2000).
-
(2000)
Mol. Cell. Biol. Res. Commun.
, vol.4
, pp. 174-180
-
-
Jana, N.R.1
-
17
-
-
0035872466
-
Tamoxifen-induced antitumorigenic/antiestrogenic action synergized by a selective aryl hydrocarbon receptor modulator
-
McDougal, A., Wormke, M., Calvin, J. & Safe, S. Tamoxifen-induced antitumorigenic/antiestrogenic action synergized by a selective aryl hydrocarbon receptor modulator. Cancer Res. 61, 3902-3907 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 3902-3907
-
-
McDougal, A.1
Wormke, M.2
Calvin, J.3
Safe, S.4
-
18
-
-
84868140854
-
The role of aryl hydrocarbon receptor and crosstalk with estrogen receptor in response of breast cancer cells to the novel antitumor agents benzothiazoles and aminoflavone
-
Callero, M. A. & Loaiza-Perez, A. I. The role of aryl hydrocarbon receptor and crosstalk with estrogen receptor in response of breast cancer cells to the novel antitumor agents benzothiazoles and aminoflavone. Int. J. Breast cancer 2011, 923250 (2011).
-
(2011)
Int. J. Breast Cancer
, vol.2011
, pp. 923250
-
-
Callero, M.A.1
Loaiza-Perez, A.I.2
-
19
-
-
0037463319
-
DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells
-
Trapani, V. et al. DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells. Br. J. Cancer 88, 599-605 (2003).
-
(2003)
Br. J. Cancer
, vol.88
, pp. 599-605
-
-
Trapani, V.1
-
20
-
-
0036140930
-
Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole
-
Loaiza-Perez, A. I. et al. Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole. Mol. Pharmacol. 61, 13-19 (2002).
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 13-19
-
-
Loaiza-Perez, A.I.1
-
21
-
-
0036463840
-
Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles
-
Bradshaw, T. D. et al. Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles. Mol. Cancer Ther. 1, 239-246 (2002).
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 239-246
-
-
Bradshaw, T.D.1
-
22
-
-
0032842573
-
Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer
-
Safe, S., Qin, C. & McDougal, A. Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer. Expert Opin. Investig. Drugs 8, 1385-1396 (1999).
-
(1999)
Expert Opin. Investig. Drugs
, vol.8
, pp. 1385-1396
-
-
Safe, S.1
Qin, C.2
McDougal, A.3
-
23
-
-
58149209724
-
Comparative properties of the nuclear aryl hydrocarbon (Ah) receptor complex from several human cell lines
-
Wang, X. et al. Comparative properties of the nuclear aryl hydrocarbon (Ah) receptor complex from several human cell lines. Eur. J. Pharmacol. 293, 191-205 (1995).
-
(1995)
Eur. J. Pharmacol.
, vol.293
, pp. 191-205
-
-
Wang, X.1
-
24
-
-
0031426303
-
Mechanism of inhibition of MDA-MB-468 breast cancer cell growth by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
-
Wang, W. L., Porter, W., Burghardt, R. & Safe, S. H. Mechanism of inhibition of MDA-MB-468 breast cancer cell growth by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Carcinogenesis 18, 925-933 (1997).
-
(1997)
Carcinogenesis
, vol.18
, pp. 925-933
-
-
Wang, W.L.1
Porter, W.2
Burghardt, R.3
Safe, S.H.4
-
25
-
-
78649243636
-
Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer
-
Patani, N., Jiang, W., Newbold, R. & Mokbel, K. Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer. J. Carcinog. 9, 9 (2010).
-
(2010)
J. Carcinog.
, vol.9
, pp. 9
-
-
Patani, N.1
Jiang, W.2
Newbold, R.3
Mokbel, K.4
-
26
-
-
84907907479
-
Ubiquitin ligase CHIP suppresses cancer stem cell properties in a population of breast cancer cells
-
Tsuchiya, M. et al. Ubiquitin ligase CHIP suppresses cancer stem cell properties in a population of breast cancer cells. Biochem. Biophys. Res. Commun. 452, 928-932 (2014).
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.452
, pp. 928-932
-
-
Tsuchiya, M.1
-
27
-
-
78149487540
-
Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist
-
Prud'homme, G. J. et al. Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist. PLoS One 5, e13831 ( 2010).
-
(2010)
PLoS One
, vol.5
, pp. e13831
-
-
Prud'Homme, G.J.1
-
28
-
-
0034726057
-
Crosstalk between estrogen receptor alpha and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes
-
Wormke, M., Stoner, M., Saville, B. & Safe, S. Crosstalk between estrogen receptor alpha and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes. FEBS Lett. 478, 109-112 (2000).
-
(2000)
FEBS Lett.
, vol.478
, pp. 109-112
-
-
Wormke, M.1
Stoner, M.2
Saville, B.3
Safe, S.4
-
29
-
-
0037373474
-
The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes
-
Wormke, M. et al. The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes. Mol. Cell Biol. 23, 1843-1855 (2003).
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 1843-1855
-
-
Wormke, M.1
-
30
-
-
34248529666
-
Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
-
Wang, J., Guo, L. P., Chen, L. Z., Zeng, Y. X. & Lu, S. H. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res. 67, 3716-3724 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 3716-3724
-
-
Wang, J.1
Guo, L.P.2
Chen, L.Z.3
Zeng, Y.X.4
Lu, S.H.5
-
31
-
-
79955608022
-
Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
-
Yu, F. et al. Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion. Oncogene 30, 2161-2172 (2011).
-
(2011)
Oncogene
, vol.30
, pp. 2161-2172
-
-
Yu, F.1
-
32
-
-
18944375734
-
Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
-
Dontu, G. et al. Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells. Breast Cancer Res. 6, R605-615 (2004).
-
(2004)
Breast Cancer Res.
, vol.6
, pp. R605-615
-
-
Dontu, G.1
-
33
-
-
76549084826
-
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
-
Harrison, H. et al. Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer Res. 70, 709-718 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 709-718
-
-
Harrison, H.1
-
34
-
-
84887459688
-
A nonclassical vitamin D receptor pathway suppresses renal fibrosis
-
Ito, I. et al. A nonclassical vitamin D receptor pathway suppresses renal fibrosis. J. Clin. Invest. 123, 4579-4594 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 4579-4594
-
-
Ito, I.1
-
35
-
-
78649707280
-
Nicotine increases cancer stem cell population in MCF-7 cells
-
Hirata, N., Sekino, Y. & Kanda, Y. Nicotine increases cancer stem cell population in MCF-7 cells. Biochem. Biophys. Res. Commun. 403, 138-143 (2010).
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.403
, pp. 138-143
-
-
Hirata, N.1
Sekino, Y.2
Kanda, Y.3
|