Purely aqueous PLGA nanoparticulate formulations of curcumin exhibit enhanced anticancer activity with dependence on the combination of the carrier

International Journal of Pharmaceutics

Volumn 425, Issue 1-2, 2012, Pages 44-52

  Nair, K Lekha ^a   Thulasidasan, Arun Kumar T ^a   Deepa, G ^a   Anto, Ruby John ^a   Kumar, G S Vinod ^a  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

Author keywords

Antitumor activity; Aqueous nanocurcumin; Curcumin; HeLa; PLGA combinations

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CURCUMIN; LIPOCORTIN 5; NANOCURCUMIN; NANOPARTICLE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYGLACTIN; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CLONOGENESIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; FEMALE; FLUORESCENCE; GEL MOBILITY SHIFT ASSAY; HELA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NANOENCAPSULATION; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; UTERINE CERVIX CANCER;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; CURCUMIN; DRUG CARRIERS; HELA CELLS; HUMANS; LACTIC ACID; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; POLY(ADP-RIBOSE) POLYMERASES; POLYGLYCOLIC ACID; TRANSCRIPTION FACTOR RELA;

EID: 84857044067     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.01.003     Document Type: Article

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