Enhancing reactivity for bioorthogonal pretargeting by unmasking antibody-conjugated trans -cyclooctenes

Bioconjugate Chemistry

Volumn 26, Issue 2, 2015, Pages 352-360

  Rahim, Maha K ^a   Kota, Rajesh ^a   Haun, Jered B ^a,b  

^a University of California at Irvine   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOADDITION; HYDROPHOBICITY; MOLECULAR IMAGING; MONOCLONAL ANTIBODIES; SEMICONDUCTOR QUANTUM DOTS;

AMINE COUPLING; CELL-BASED; COUPLING PROCEDURE; CYCLOADDITION REACTION; CYCLOOCTENE; FUNCTIONAL DENSITY; HYDROPHILICS; HYDROPHOBIC INTERACTIONS; TETRAZINES; TRANS-CIS ISOMERIZATION;

POLYETHYLENE GLYCOLS;

AMINE; ANTIBODY CONJUGATE; MACROGOL; MONOCLONAL ANTIBODY; QUANTUM DOT; TETRAZINE DERIVATIVE; AZIDE; CYCLOOCTANE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; MACROGOL DERIVATIVE;

ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; CONJUGATION; CONTROLLED STUDY; CYCLOADDITION; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; ISOMERIZATION; MOLECULAR INTERACTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DIAGNOSTIC USE; FLUORESCENCE IMAGING; IMMUNOLOGY; ISOMERISM; MOUSE; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; AZIDES; CELL LINE, TUMOR; CYCLOADDITION REACTION; CYCLOOCTANES; HUMANS; IMMUNOCONJUGATES; ISOMERISM; MICE; MODELS, MOLECULAR; OPTICAL IMAGING; POLYETHYLENE GLYCOLS; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84923222516     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc500605g     Document Type: Article

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