Population genetic simulations of complex phenotypes with implications for rare variant association tests

Genetic Epidemiology

Volumn 39, Issue 1, 2015, Pages 35-44

  Uricchio, Lawrence H ^a   Torres, Raul ^a   Witte, John S ^a,b   Hernandez, Ryan D ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Association tests; Complex phenotypes; Demography; Forward simulations; Natural selection; Rare variants

Indexed keywords

AFRICAN; ARTICLE; DEMOGRAPHY; DNA SEQUENCE; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC SELECTION; GENETIC VARIABILITY; HAPLOTYPE; NATURAL SELECTION; PHENOTYPIC VARIATION; POPULATION GENETICS; POPULATION GROWTH; SIMULATION; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENETIC VARIATION; HUMAN; HUMAN GENOME; SAMPLE SIZE;

COMPUTER SIMULATION; GENETIC VARIATION; GENETICS, POPULATION; GENOME, HUMAN; HAPLOTYPES; HUMANS; MODELS, GENETIC; SAMPLE SIZE; SELECTION, GENETIC;

EID: 84923166091     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.21866     Document Type: Article

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