Low toxicity and long circulation time of Polyampholyte-coated magnetic nanoparticles for blood pool contrast agents

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Wang, Qi ^a,b   Shen, Ming ^a   Zhao, Tao ^a   Xu, Yuanyuan ^a   Lin, Jiang ^c   Duan, Yourong ^a   Gu, Hongchen ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC ACID RESIN; AUTACOID; BIOMATERIAL; CARBOPOL 940; CONTRAST MEDIUM; CYTOKINE; MAGNETITE NANOPARTICLE; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL; BLOOD CLOTTING; CELL DIFFERENTIATION; CHEMISTRY; COMPLEMENT ACTIVATION; DRUG EFFECTS; HEMOLYSIS; HUMAN; METABOLISM; MOUSE; PATHOLOGY; PROTHROMBIN TIME; RABBIT; TIME; TISSUE DISTRIBUTION; UMBILICAL VEIN ENDOTHELIAL CELL; VEIN;

ACRYLIC RESINS; ANIMALS; BLOOD COAGULATION; CELL DIFFERENTIATION; COATED MATERIALS, BIOCOMPATIBLE; COMPLEMENT ACTIVATION; CONTRAST MEDIA; CYTOKINES; HEMOLYSIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; MAGNETITE NANOPARTICLES; MICE; PROTHROMBIN TIME; RABBITS; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TISSUE DISTRIBUTION; VEINS;

EID: 84923094758     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep07774     Document Type: Article

References (42)

1. Laurent, S. et al. Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem Rev 108, 2064-2110 (2008).
2. Reddy, L. H., Arias, J. L., Nicolas, J. & Couvreur, P. Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications. Chem Rev 112, 5818-5878 (2012).
3. Mahmoudi, M., Sant, S., Wang, B., Laurent, S. & Sen, T. Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy. Adv Drug Deliv Rev 63, 24-46 (2011).
4. Qiao, R., Yang, C. & Gao, M. Superparamagnetic iron oxide nanoparticles: from preparations to in vivo MRI applications. J Mater Chem 19, 6274-6293 (2009).
5. Jun, Y. W., Lee, J. H. & Cheon, J. Chemical design of nanoparticle probes for highperformance magnetic resonance imaging. Angew Chem Int Ed Engl 47, 5122-5135 (2008).
6. Tromsdorf, U. I., Bruns, O. T., Salmen, S. C., Beisiegel, U. & Weller, H. A highly effective, nontoxic T1 MR contrast agent based on ultrasmall PEGylated iron oxide nanoparticles. Nano Lett 9, 4434-40 (2009).
7. Neuwelt, E. A. et al. Ultrasmall superparamagnetic iron oxides (USPIOs): a future alternative magnetic resonance (MR) contrast agent for patients at risk for nephrogenic systemic fibrosis (NSF)? Kidney Int 75, 465-474 (2009).
8. Zhang, J., Rana, S., Srivastava, R. S. & Misra, R. D. On the chemical synthesis and drug delivery response of folate receptor-activated, polyethylene glycol-functionalized magnetite nanoparticles. Acta Biomater 4, 40-48 (2008).
9. Kawashita, M., Kawamura, K. & Li, Z. PMMA-based bone cements containing magnetite particles for the hyperthermia of cancer. Acta Biomater 6, 3187-3192 (2010).
10. Yuan, Q., Venkatasubramanian, R., Hein, S. & Misra, R. D. A stimulus-responsive magnetic nanoparticle drug carrier: magnetite encapsulated by chitosan-grafted-copolymer. Acta Biomater 4, 1024-1037 (2008).
11. Ruiz, A. et al. Short-chain PEG molecules strongly bound to magnetic nanoparticle for MRI long circulating agents. Acta Biomater 9, 6421-6430 (2013).
12. Liu, T. Y. & Huang, T. C. A novel drug vehicle capable of ultrasound-triggered release with MRI functions. Acta Biomater 7, 3927-3934 (2011).
13. Zhu, A. et al. Polysaccharide surface modified Fe3O4 nanoparticles for camptothecin loading and release. Acta Biomater 5, 1489-1498 (2009).
14. Yoo, J. W., Chambers, E. & Mitragotri, S. Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects. Curr Pharm Des 16, 2298-2307 (2010).
15. Aggarwal, P., Hall, J. B., McLeland, C. B., Dobrovolskaia, M. A. & McNeil, S. E. Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv Drug Deliv Rev 61, 428-437 (2009).
16. Estephan, Z. G., Jaber, J. A. & Schlenoff, J. B. Zwitterion-stabilized silica nanoparticles: toward nonstick nano. Langmuir 26, 16884-16889 (2010).
17. Estephan, Z. G., Schlenoff, P. S. & Schlenoff, J. B. Zwitteration as an alternative to PEGylation. Langmuir 27, 6794-6800 (2011).
18. Chen, S., Li, L., Zhao, C. & Zheng, J. Surface hydration: principles and applications toward low-fouling/nonfouling biomaterials. Polymer 51, 5283-5293 (2010).
19. Jiang, S. & Cao, Z. Ultralow-fouling, functionalizable, and hydrolyzable zwitterionic materials and their derivatives for biological applications. Adv Mater 22, 920-932 (2010).
20. Petri-Fink, A., Chastellain, M., Juillerat-Jeanneret, L., Ferrari, A. & Hofmann, H. Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells. Biomaterials 26, 2685-2694 (2005).
21. Wei, H. et al. Compact zwitterion-coated iron oxide nanoparticles for biological applications. Nano Lett 12, 22-25 (2012).
22. Wei, H., Bruns, O.T., Chen, O. & Bawendi, M. G. Compact zwitterion-coated iron oxide nanoparticles for in vitro and in vivo imaging. Integr Biol (Camb) 5, 108-114 (2013).
23. Kim, D. et al. Facile preparation of zwitterion-stabilized superparamagnetic iron oxide nanoparticles (ZSPIONs) as an MR contrast agent for in vivo applications. Langmuir 28, 9634-9639 (2012).
24. Xiao, W. C. et al. Microwave-assisted synthesis of magnetite nanoparticles for MR blood pool contrast agents. J Magn Magn Mater 324, 488-494 (2012).
25. Xiao, W. et al. Prolonged in vivo circulation time by zwitterionic modification of magnetite nanoparticles for blood pool contrast agents. Contrast Media Mol Imaging 7, 320-327 (2012).
26. Zhao, T., Chen, K. & Gu, H. Investigations on the interactions of proteins with polyampholyte-coated magnetite nanoparticles. J Phys Chem B117, 14129-14135 (2013).
27. Chou, F. Y., Lai, J. Y., Shih, C. M., Tsai, M. C. & Lue, S. J. In vitro biocompatibility of magnetic thermo-responsive nanohydrogel particles of poly(N-isopropylacrylamide-co-acrylic acid) with Fe3O4 cores: effect of particle size and chemical composition. Colloids Surf B Biointerfaces 104, 66-74 (2013).
28. Lee, J. H. et al. Heparin-coated superparamagnetic iron oxide for in vivo MR imaging of human MSCs. Biomaterials 33, 4861-4871 (2012).
29. Amna, T. et al. Electrospun Fe3O4/TiO2 hybrid nanofibers and their in vitro biocompatibility: Prospective matrix for satellite cell adhesion and cultivation. Mat Sci Eng C-Mater 33, 707-713 (2013).
30. Wei, Y. et al. Synthesis and cellular compatibility of biomineralized Fe3O4 nanoparticles in tumor cells targeting peptides. Colloids Surf B Biointerfaces 107, 180-188 (2013).
31. Wang, Q. et al. Pluronic-poly[alpha-(4-aminobutyl)-1-glycolic acid] polymeric micelle-like nanoparticles as carrier for drug delivery. J Nanosci Nanotechnol 14, 4843-4850 (2014).
32. Wang, Q.etal. Uptakemechanism and endosomal fate ofdrug-phospholipid lipid nanoparticles in subcutaneous and in situ hepatoma. J Biomed Nanotechnol 10, 993-1003 (2014)
33. Wang, Q., Qin, L., Sun, Y., Shen, M. & Duan, Y. R. Study of siRNA loaded PS-mPEG/CaP nanospheres on lung cancer. J Nanopart Res DOI: 10.1007/s11051-014-2421-3 (2014).
34. Li, J. et al. Preparation of biocompatible chitosan grafted poly(lactic acid) nanoparticles. Int J Biol Macromol 51, 221-227 (2012).
35. Andrade, F. K. et al. Studies on the hemocompatibility of bacterial cellulose. J Biomed Mater Res A 98, 554-566 (2011).
36. Wang, Q. et al. Preparation, blood coagulation and cell compatibility evaluation of chitosan-graft-polylactide copolymers. Biomed Mater 9, 015007 (2014).
37. Wang, Q. et al. Preparation and properties of biocompatible PS-PEG/calcium phosphate nanospheres. Nanotoxicology (2014).
38. Zhang, E., Chen, H. & Shen, F. Biocorrosion properties and blood and cell compatibility of pure iron as a biodegradable biomaterial. J Mater Sci Mater Med 21, 2151-2163 (2010).
39. Shenoi, R. A., Lai, B. F., Imran, U. M., Brooks, D. E. & Kizhakkedathu, J. N. Biodegradable polyglycerols with randomly distributed ketal groups as multifunctional drug delivery systems. Biomaterials 34, 6068-6081 (2013).
40. Xiong, F., Xiong, C., Yao, J., Chen, X. & Gu, N. Preparation, characterization and evaluation of breviscapine lipid emulsions coated with monooleate-PEG-COOH. Int J Pharm 421, 275-282 (2011).
41. She, W. et al. The potential of self-assembled, pH-responsive nanoparticles of mPEGylated peptide dendron-doxorubicin conjugates for cancer therapy. Biomaterials 34, 1613-1623 (2013).
42. Cole, A. J., David, A. E., Wang, J., Galban, C. J. & Yang, V. C. Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles. Biomaterials 32, 6291-6301 (2011).