Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers

EMBO Journal

Volumn 34, Issue 4, 2015, Pages 430-447

  Nikolaou, Kostas C ^a   Moulos, Panagiotis ^a   Chalepakis, George ^b   Hatzis, Pantelis ^a   Oda, Hisanobu ^c,d   Reinberg, Danny ^e   Talianidis, Iannis ^a  

^a BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

^c KYUSHU UNIVERSITY   (Japan)

^d National Hospital Organization   (Japan)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ductal progenitors; Hepatocellular carcinoma; Histone methylase

Indexed keywords

ONCOPROTEIN; PR SET7 POTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; SET8 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CELL DEATH; CELL DIFFERENTIATION; CELL GROWTH; CELL REGENERATION; CELL RENEWAL; CONTROLLED STUDY; EMBRYO; FIBROSIS; G2 PHASE CELL CYCLE CHECKPOINT; GENE DELETION; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIVER; LIVER CELL; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; STEM CELL; TUMOR XENOGRAFT; ANIMAL; ENZYMOLOGY; METABOLISM; METHYLATION; TUMOR CELL CULTURE;

MUS;

ANIMALS; CARCINOMA, HEPATOCELLULAR; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; LIVER NEOPLASMS; MALE; METHYLATION; MICE; NEOPLASTIC STEM CELLS; TUMOR CELLS, CULTURED;

EID: 84923083350     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201489279     Document Type: Article

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