-
1
-
-
0036176510
-
Mechanisms of cancer drug resistance
-
Gottesman MM: Mechanisms of cancer drug resistance. Annu Rev Med 53: 615-627, 2002.
-
(2002)
Annu Rev Med
, vol.53
, pp. 615-627
-
-
Gottesman, M.M.1
-
2
-
-
84873180150
-
The role of microvesicles in cancer progression and drug resistance
-
Jorfi S and Inal JM: The role of microvesicles in cancer progression and drug resistance. Biochem Soc Trans 41: 293-298, 2013.
-
(2013)
Biochem Soc Trans
, vol.41
, pp. 293-298
-
-
Jorfi, S.1
Inal, J.M.2
-
3
-
-
80054972160
-
3D tumour models: Novel in vitro approaches to cancer studies
-
Nyga A, Cheema U and Loizidou M: 3D tumour models: novel in vitro approaches to cancer studies. J Cell Commun Signal 5: 239-248, 2011.
-
(2011)
J Cell Commun Signal
, vol.5
, pp. 239-248
-
-
Nyga, A.1
Cheema, U.2
Loizidou, M.3
-
4
-
-
84880924265
-
The immune microenvironment of human tumors: General significance and clinical impact
-
Fridman WH, Dieu-Nosjean MC, Pages F, Cremer I, Damotte D, Sautes-Fridman C and Galon J: The immune microenvironment of human tumors: general significance and clinical impact. Cancer Microenviron 6: 117-122, 2013.
-
(2013)
Cancer Microenviron
, vol.6
, pp. 117-122
-
-
Fridman, W.H.1
Dieu-Nosjean, M.C.2
Pages, F.3
Cremer, I.4
Damotte, D.5
Sautes-Fridman, C.6
Galon, J.7
-
5
-
-
84872784433
-
Spheroid culture as a tool for creating 3D complex tissues
-
Fennema E, Rivron N, Rouwkema J, van Blitterswijk C and de Boer J: Spheroid culture as a tool for creating 3D complex tissues. Trends Biotechnol 31: 108-115, 2013.
-
(2013)
Trends Biotechnol
, vol.31
, pp. 108-115
-
-
Fennema, E.1
Rivron, N.2
Rouwkema, J.3
Van Blitterswijk, C.4
De Boer, J.5
-
6
-
-
84875174768
-
The role of tumour-stromal interactions in modifying drug response: Challenges and opportunities
-
McMillin DW, Negri JM and Mitsiades CS: The role of tumour-stromal interactions in modifying drug response: challenges and opportunities. Nat Rev Drug Discov 12: 217-228, 2013.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 217-228
-
-
McMillin, D.W.1
Negri, J.M.2
Mitsiades, C.S.3
-
7
-
-
0141520276
-
Drug resistance and the microenvironment: Nature and nurture
-
Morin PJ: Drug resistance and the microenvironment: nature and nurture. Drug Resist Updat 6: 169-172, 2003.
-
(2003)
Drug Resist Updat
, vol.6
, pp. 169-172
-
-
Morin, P.J.1
-
8
-
-
10344256151
-
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular prostate tumor spheroids by hyperthermia and reactive oxygen species
-
DOI 10.1002/ijc.20596
-
Wartenberg M, Gronczynska S, Bekhite MM, Saric T, Niedermeier W, Hescheler J and Sauer H: Regulation of the multidrug resistance transporter P-glycoprotein in multicellular prostate tumor spheroids by hyperthermia and reactive oxygen species. Int J Cancer 113: 229-240, 2005. (Pubitemid 39628313)
-
(2005)
International Journal of Cancer
, vol.113
, Issue.2
, pp. 229-240
-
-
Wartenberg, M.1
Gronczynska, S.2
Bekhite, M.M.3
Saric, T.4
Niedermeier, W.5
Hescheler, J.6
Sauer, H.7
-
9
-
-
34547931078
-
Modeling Tissue Morphogenesis and Cancer in 3D
-
DOI 10.1016/j.cell.2007.08.006, PII S0092867407010288
-
Yamada KM and Cukierman E: Modeling tissue morphogenesis and cancer in 3D. Cell 130: 601-610, 2007. (Pubitemid 47268064)
-
(2007)
Cell
, vol.130
, Issue.4
, pp. 601-610
-
-
Yamada, K.M.1
Cukierman, E.2
-
10
-
-
56049090579
-
3-D tumor model for in vitro evaluation of anticancer drugs
-
Horning JL, Sahoo SK, Vijayaraghavalu S, Dimitrijevic S, Vasir JK, Jain TK, Panda AK and Labhasetwar V: 3-D tumor model for in vitro evaluation of anticancer drugs. Mol Pharm 5: 849-862, 2008.
-
(2008)
Mol Pharm
, vol.5
, pp. 849-862
-
-
Horning, J.L.1
Sahoo, S.K.2
Vijayaraghavalu, S.3
Dimitrijevic, S.4
Vasir, J.K.5
Jain, T.K.6
Panda, A.K.7
Labhasetwar, V.8
-
11
-
-
84857763458
-
The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer
-
Chitcholtan K, Sykes PH and Evans JJ: The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer. J Transl Med 10: 38, 2012.
-
(2012)
J Transl Med
, vol.10
, pp. 38
-
-
Chitcholtan, K.1
Sykes, P.H.2
Evans, J.J.3
-
12
-
-
84877255483
-
A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro
-
Lee JM, Mhawech-Fauceglia P, Lee N, Parsanian LC, Lin YG, Gayther SA and Lawrenson K: A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro. Lab Invest 93: 528-542, 2013.
-
(2013)
Lab Invest
, vol.93
, pp. 528-542
-
-
Lee, J.M.1
Mhawech-Fauceglia, P.2
Lee, N.3
Parsanian, L.C.4
Lin, Y.G.5
Gayther, S.A.6
Lawrenson, K.7
-
13
-
-
84874239307
-
3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing
-
Longati P, Jia X, Eimer J, Wagman A, Witt MR, Rehnmark S, Verbeke C, Toftgard R, Lohr M and Heuchel RL: 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing. BMC Cancer 13: 95, 2013.
-
(2013)
BMC Cancer
, vol.13
, pp. 95
-
-
Longati, P.1
Jia, X.2
Eimer, J.3
Wagman, A.4
Witt, M.R.5
Rehnmark, S.6
Verbeke, C.7
Toftgard, R.8
Lohr, M.9
Heuchel, R.L.10
-
14
-
-
84883810070
-
Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model
-
Yeon SE, No da Y, Lee SH, Nam SW, Oh IH, Lee J and Kuh HJ: Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model. PLoS One 8: e73345, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Yeon, S.E.1
No Da, Y.2
Lee, S.H.3
Nam, S.W.4
Oh, I.H.5
Lee, J.6
Kuh, H.J.7
-
15
-
-
69949164633
-
Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells
-
Hehlgans S, Eke I, Storch K, Haase M, Baretton GB and Cordes N: Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells. Radiother Oncol 92: 362-370, 2009.
-
(2009)
Radiother Oncol
, vol.92
, pp. 362-370
-
-
Hehlgans, S.1
Eke, I.2
Storch, K.3
Haase, M.4
Baretton, G.B.5
Cordes, N.6
-
16
-
-
77958613855
-
Activity of anticancer agents in a three-dimensional cell culture model
-
Nirmalanandhan VS, Duren A, Hendricks P, Vielhauer G and Sittampalam GS: Activity of anticancer agents in a three-dimensional cell culture model. Assay Drug Dev Technol 8: 581-590, 2010.
-
(2010)
Assay Drug Dev Technol
, vol.8
, pp. 581-590
-
-
Nirmalanandhan, V.S.1
Duren, A.2
Hendricks, P.3
Vielhauer, G.4
Sittampalam, G.S.5
-
17
-
-
84872549177
-
AlgiMatrix™ based 3D cell culture system as an in-vitro tumor model for anticancer studies
-
Godugu C, Patel AR, Desai U, Andey T, Sams A and Singh M: AlgiMatrix™ based 3D cell culture system as an in-vitro tumor model for anticancer studies. PLoS One 8: e53708, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Godugu, C.1
Patel, A.R.2
Desai, U.3
Andey, T.4
Sams, A.5
Singh, M.6
-
18
-
-
77949901120
-
Adjuvant therapy in colon cancer
-
Lombardi L, Gebbia V, Silvestris N, Testa A, Colucci G and Maiello E: Adjuvant therapy in colon cancer. Oncology 77: 50-56, 2009.
-
(2009)
Oncology
, vol.77
, pp. 50-56
-
-
Lombardi, L.1
Gebbia, V.2
Silvestris, N.3
Testa, A.4
Colucci, G.5
Maiello, E.6
-
20
-
-
34247134622
-
Gene expression profile of 5-fluorouracil metabolic enzymes in primary colorectal cancer: Potential as predictive parameters for response to fluorouracil-based chemotherapy
-
Kinoshita M, Kodera Y, Hibi K, Nakayama G, Inoue T, Ohashi N, Ito Y, Koike M, Fujiwara M and Nakao A: Gene expression profile of 5-fluorouracil metabolic enzymes in primary colorectal cancer: potential as predictive parameters for response to fluorouracil-based chemotherapy. Anticancer Res 27: 851-856, 2007. (Pubitemid 46586990)
-
(2007)
Anticancer Research
, vol.27
, Issue.2
, pp. 851-856
-
-
Kinoshita, M.1
Kodera, Y.2
Hibi, K.3
Nakayama, G.4
Inoue, T.5
Ohashi, N.6
Ito, Y.7
Koike, M.8
Fujiwara, M.9
Nakao, A.10
-
21
-
-
50949094432
-
5-Fluorouracil: Mechanisms of resistance and reversal strategies
-
Zhang N, Yin Y, Xu SJ and Chen WS: 5-Fluorouracil: mechanisms of resistance and reversal strategies. Molecules 13: 1551-1569, 2008.
-
(2008)
Molecules
, vol.13
, pp. 1551-1569
-
-
Zhang, N.1
Yin, Y.2
Xu, S.J.3
Chen, W.S.4
-
22
-
-
67649380881
-
Tirapazamine: A novel agent targeting hypoxic tumor cells
-
Reddy SB and Williamson SK: Tirapazamine: a novel agent targeting hypoxic tumor cells. Expert Opin Investig Drugs 18: 77-87, 2009.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 77-87
-
-
Reddy, S.B.1
Williamson, S.K.2
-
23
-
-
1642359043
-
Microenvironmental Regulation of Proliferation in Multicellular Spheroids Is Mediated through Differential Expression of Cyclin-Dependent Kinase Inhibitors
-
DOI 10.1158/0008-5472.CAN-2902-2
-
LaRue KE, Khalil M and Freyer JP: Microenvironmental regulation of proliferation in multicellular spheroids is mediated through differential expression of cyclin-dependent kinase inhibitors. Cancer Res 64: 1621-1631, 2004. (Pubitemid 38428682)
-
(2004)
Cancer Research
, vol.64
, Issue.5
, pp. 1621-1631
-
-
LaRue, K.E.A.1
Khalil, M.2
Freyer, J.P.3
-
24
-
-
62449155864
-
The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death
-
Chari NS, Pinaire NL, Thorpe L, Medeiros LJ, Routbort MJ and McDonnell TJ: The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death. Apoptosis 14: 336-347, 2009.
-
(2009)
Apoptosis
, vol.14
, pp. 336-347
-
-
Chari, N.S.1
Pinaire, N.L.2
Thorpe, L.3
Medeiros, L.J.4
Routbort, M.J.5
McDonnell, T.J.6
-
25
-
-
3242739561
-
E-cadherin-dependent intercellular adhesion enhances chemoresistance
-
Nakamura T, Kato Y, Fuji H, Horiuchi T, Chiba Y and Tanaka K: E-cadherin-dependent intercellular adhesion enhances chemoresistance. Int J Mol Med 12: 693-700, 2003.
-
(2003)
Int J Mol Med
, vol.12
, pp. 693-700
-
-
Nakamura, T.1
Kato, Y.2
Fuji, H.3
Horiuchi, T.4
Chiba, Y.5
Tanaka, K.6
-
26
-
-
42749084082
-
The impact of p53 and p73 on aneuploidy and cancer
-
Tomasini R, Mak TW and Melino G: The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol 18: 244-252, 2008.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 244-252
-
-
Tomasini, R.1
Mak, T.W.2
Melino, G.3
-
27
-
-
84857184141
-
Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance
-
Review
-
Hafsi S, Pezzino FM, Candido S, Ligresti G, Spandidos DA, Soua Z, McCubrey JA, Travali S and Libra M: Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (Review). Int J Oncol 40: 639-644, 2012.
-
(2012)
Int J Oncol
, vol.40
, pp. 639-644
-
-
Hafsi, S.1
Pezzino, F.M.2
Candido, S.3
Ligresti, G.4
Spandidos, D.A.5
Soua, Z.6
McCubrey, J.A.7
Travali, S.8
Libra, M.9
-
28
-
-
79851490281
-
Ceramide induces apoptosis and growth arrest of human glioblastoma cells by inhibiting akt signaling pathways
-
Lee EC, Lee YS, Park NH, So KS, Chun YJ and Kim MY: Ceramide induces apoptosis and growth arrest of human glioblastoma cells by inhibiting akt signaling pathways. Biomol Therap 19: 21-26, 2011.
-
(2011)
Biomol Therap
, vol.19
, pp. 21-26
-
-
Lee, E.C.1
Lee, Y.S.2
Park, N.H.3
So, K.S.4
Chun, Y.J.5
Kim, M.Y.6
-
29
-
-
84878831559
-
Overcoming acquired resistance to anticancer therapy: Focus on the PI3K/AKT/mTOR pathway
-
Burris HA III: Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway. Cancer Chemother Pharmacol 71: 829-842, 2013.
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, pp. 829-842
-
-
Burris III, H.A.1
-
30
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
Lane DP: Cancer. p53, guardian of the genome. Nature 358: 15-16, 1992.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
31
-
-
68949083047
-
The roles of phospholipase D in EGFR signaling
-
Lee CS, Kim KL, Jang JH, Choi YS, Suh PG and Ryu SH: The roles of phospholipase D in EGFR signaling. Biochim Biophys Acta 1791: 862-868, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 862-868
-
-
Lee, C.S.1
Kim, K.L.2
Jang, J.H.3
Choi, Y.S.4
Suh, P.G.5
Ryu, S.H.6
-
32
-
-
78751480479
-
Phospholipase D meets Wnt signaling: A new target for cancer therapy
-
Kang DW, Choi KY and Min do S: Phospholipase D meets Wnt signaling: a new target for cancer therapy. Cancer Res 71: 293-297, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 293-297
-
-
Kang, D.W.1
Choi, K.Y.2
Min Do, S.3
-
33
-
-
84874111238
-
Phosphorylated tubulin adaptor protein CRMP-2 as prognostic marker and candidate therapeutic target for NSCLC
-
Oliemuller E, Pelaez R, Garasa S, Pajares MJ, Agorreta J, Pio R, Montuenga LM, Teijeira A, Llanos S and Rouzaut A: Phosphorylated tubulin adaptor protein CRMP-2 as prognostic marker and candidate therapeutic target for NSCLC. Int J Cancer 132: 1986-1995, 2013.
-
(2013)
Int J Cancer
, vol.132
, pp. 1986-1995
-
-
Oliemuller, E.1
Pelaez, R.2
Garasa, S.3
Pajares, M.J.4
Agorreta, J.5
Pio, R.6
Montuenga, L.M.7
Teijeira, A.8
Llanos, S.9
Rouzaut, A.10
-
34
-
-
66849142178
-
Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells
-
Barkley LR, Song IY, Zou Y and Vaziri C: Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells. Cell Cycle 8: 1577-1588, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 1577-1588
-
-
Barkley, L.R.1
Song, I.Y.2
Zou, Y.3
Vaziri, C.4
-
35
-
-
24644481520
-
Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma
-
Obama K, Ura K, Satoh S, Nakamura Y and Furukawa Y: Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma. Oncol Rep 14: 701-706, 2005.
-
(2005)
Oncol Rep
, vol.14
, pp. 701-706
-
-
Obama, K.1
Ura, K.2
Satoh, S.3
Nakamura, Y.4
Furukawa, Y.5
-
36
-
-
33745076486
-
Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival
-
DOI 10.1002/pmic.200500629
-
Kim H, Kang HJ, You KT, Kim SH, Lee KY, Kim TI, Kim C, Song SY, Kim HJ, Lee C, et al : Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival. Proteomics 6: 3466-3476, 2006. (Pubitemid 43886162)
-
(2006)
Proteomics
, vol.6
, Issue.11
, pp. 3466-3476
-
-
Kim, H.1
Kang, H.J.2
You, K.T.3
Kim, S.H.4
Lee, K.Y.5
Kim, T.I.6
Kim, C.7
Song, S.Y.8
Kim, H.-J.9
Lee, C.10
Kim, H.11
-
37
-
-
84877990763
-
Reduced selenium-binding protein 1 in breast cancer correlates with poor survival and resistance to the anti-proliferative effects of selenium
-
Zhang S, Li F, Younes M, Liu H, Chen C and Yao Q: Reduced selenium-binding protein 1 in breast cancer correlates with poor survival and resistance to the anti-proliferative effects of selenium. PLoS One 8: e63702, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Zhang, S.1
Li, F.2
Younes, M.3
Liu, H.4
Chen, C.5
Yao, Q.6
-
38
-
-
55949102955
-
Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer
-
Li T, Yang W, Li M, Byun DS, Tong C, Nasser S, Zhuang M, Arango D, Mariadason JM and Augenlicht LH: Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer. Mol Nutr Food Res 52: 1289-1299, 2008.
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 1289-1299
-
-
Li, T.1
Yang, W.2
Li, M.3
Byun, D.S.4
Tong, C.5
Nasser, S.6
Zhuang, M.7
Arango, D.8
Mariadason, J.M.9
Augenlicht, L.H.10
|