Prenatal stress induces learning deficits and is associated with a decrease in granules and CA3 cell dendritic tree size in rat hippocampus

Anatomical Science International

Volumn 82, Issue 4, 2007, Pages 211-217

  Hosseini Sharifabad, Mohammad ^a   Hadinedoushan, Hossein ^b  

^a SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Research and Clinical Centre for Infertility   (Iran)

Author keywords

Dendrites; Hippocampus; Prenatal stress; Spatial learning

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL GRANULE; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GOLGI COMPLEX; HIPPOCAMPUS; LEARNING DISORDER; MALE; MAZE TEST; NERVE CELL LESION; NEUROPATHOLOGY; NONHUMAN; PRENATAL EXPOSURE; PRENATAL STRESS; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; QUANTITATIVE ANALYSIS; RAT; SPATIAL MEMORY;

ANIMALS; CORTICOSTERONE; CYTOPLASMIC GRANULES; DENDRITES; FEMALE; HIPPOCAMPUS; LEARNING DISORDERS; MALE; MAZE LEARNING; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PYRAMIDAL CELLS; RATS; RATS, WISTAR; STRESS; SWIMMING;

EID: 36049030603     PISSN: 14476959     EISSN: 1447073X     Source Type: Journal    
DOI: 10.1111/j.1447-073X.2007.00186.x     Document Type: Article

References (37)

1. Aleksandrov AA, Polyakova ON, Batuev AS (2001) The effects of prenatal stress on learning in rats in a Morris maze. Neurosci Behav Physiol 31, 71-4.
2. Amaral DG, Witter MP (1989) The three-dimensional organization of the hippocampal formation: A review of anatomical data. Neuroscience 31, 571-91.
3. Barbazanges A, Piazza PV, Le Moal M, Maccari S (1996) Maternal glucocorticoid secretion mediates long-term effects of prenatal stress. J Neurosci 16, 3943-9.
4. Chapman RH, Stern JM (1978) Maternal stress and pituitary-adrenal manipulations during pregnancy in rats: Effects on morphology and sexual behavior of male offspring. J Comp Physiol Psychol 92, 1074-83.
5. Cintra A, Zoli M, Rosen L et al. (1994) Mapping and computer assisted morphometry and microdensitometry of glucocorticoid receptor immunoreactive neurons and glial cells in the rat central nervous system. Neuroscience 62, 843-97.
6. Conrad CD (2006) What is the functional significance of chronic stress-induced CA3 dendritic retraction within the hippocampus? Behav Cogn Neurosci Rev 5, 41-60.
7. Cunningham TJ (1982) Naturally occurring neuron death and its regulation by developing neural pathways. Int Rev Cytol 74, 163-86.
8. De Ruiter JP, Uylings HBM (1987) Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia. Brain Res 402, 217-29.
9. Fride E, Dan Y, Feldon J, Halevy G, Weinstock M (1986) Effects of prenatal stress on vulnerability to stress on prepubertal and adult rats. Physiol Behav 37, 681-7.
10. Gaarskjaer FB (1986) The organization and development of the hippocampal mossy fiber system. Brain Res Rev 11, 335-57.
11. Gabbott PL, Somogyi J (1994) The 'single' section Golgi impregnation procedure: Methodological description. J Neurosci Methods 11, 221-30.
12. Garrud P, Rawlins JNP, O'Keefe J (1982) Place navigation impaired in rats with hippocampal lesions. Nature 297, 681-3.
13. Gould E, Woolley CS, McEwen BS (1990) Short-term glucocorticoid manipulations affects neuronal morphology and survival in the adult dentate gyrus. Neuroscience 37, 367-75.
14. Green EJ, Jurska JM (1985) The dendritic morphology of hippocampal dentate gyrus cells varies with their position in the granular cell layer: A quantitative Golgi study. Exp Brain Res 59, 582-6.
15. Henry C, Kabbaj M, Simon H, Le Moal M, Maccari S (1994) Prenatal stresses increases the hypothalamo-pituitary-adrenal axis response in young and adult rats. J Neuroendocrinol 6, 341-5.
16. Horner CH (1993) Plasticity of the dendritic spine. Prog Neurobiol 41, 281-321.
17. Koehl M, Darnaudery M, Dulluc J, Van Reeth O, Le Moal M, Maccari S (1999) Prenatal stress alters circadian activity of hypothalamo-pituitary-adrenal axis and hippocampal corticosteroid receptors in adult rats of both genders. J Neurobiol 40, 302-15.
18. Lemaire V, Koehl M, Moal Le M, Abrous DN (2000) Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus. Proc Natl Acad Sci 97, 11 032-7.
19. Li X, Zhu Z, Chen W (2003) The effect of different stage of prenatal stress on the spatial learning and memory of offspring rats. Chin J Behav Med Sci 12, 1479-97.
20. Maccari S, Darnaudery M, Morley-Fletcher S, Zuena AR, Cinque C, Van Reeth O (2003) Prenatal stress and long-term consequences: Implications of glucocorticoid hormones. Neurosci Biobehav Rev 27, 119-27.
21. Magarinos AM, McEwen BS (1995) Stress-induced atrophy of apical dendrites of hippocampal CA3 neurons: Comparison of stressors. Neuroscience 69, 83-8.
22. Purves D (1988) Body and Brain, A Trophic Theory of Neural Connections. Harvard University Press, Cambridge.
23. Reul JM, De Kloet ER (1985) Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation. Endocrinology 117, 2505-11.
24. Rusakov DA, Davies HA, Harrison E et al. (1997) Ultrastructural synaptic correlates of spatial learning in rat hippocampus. Neuroscience 80, 69-77.
25. Sapolsky RM (1999) Glucocorticoids, stress and their adverse neurological effects: Relevance to aging. Exp Gerontol 34, 721-32.
26. Schmitz C, Rhodes ME, Bludau M et al. (2002) Depression: Reduced number of granule cells in the hippocampus of female, but not male, rats due to prenatal restraint stress. Mol Psychiatry 7, 810-13.
27. Sousa N, Lukoyanov NV, Madeira MD, Almeida OF, Paula-Barbosa MM (2000) Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience 97, 253-66.
28. Szuran TF, Pliska V, Pokorny J, Welzl H (2000) Prenatal stress in rats: Effects on plasma corticosterone, hippocampal glucocorticoid receptors, and maze performance. Physiol Behav 71, 353-62.
29. Takahashi LK (1998) Prenatal stress: Consequences of glucocorticoids on hippocampal development and function. Int J Dev Neurosci 16, 199-207.
30. Uemura E, Carriquiry A, Kliemann W, Goodwin J (1995) Mathematical modelling of dendritic growth in vitro. Brain Res 671, 187-94.
31. Uylings HBM, Ruiz-Marcos A, Van Pelt J (1986) The metric analysis of three-dimensional dendritic patterns: A methodological review. J Neurosci Methods 18, 127-51.
32. Ward HE, Johnson EA, Salm AK, Birkle DL (2000) Effects of prenatal stress on defensive withdrawal behavior and corticotropin releasing factor systems in rat brain. Physiol Behav 70, 359-66.
33. Ward IL, Weisz J (1984) Differential effects of maternal stress on circulating levels of corticosterone, progesterone, and testosterone in male and female rat fetuses and their mothers. Endocrinology 114, 1635-44.
34. Watanabe Y, Gould E, McEwen BS (1992) Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res 588, 341-5.
35. Woolley CS, Gould E, McEwen BS (1990) Exposure to excess glucocorticoids alters dendritic morphology of adult pyramidal neurons. Brain Res 531, 225-31.
36. Zarrow MO, Philpott J, Deneberg V (1970) Passage of 14C-4-corticosterone from the rat mother to the fetus and neonate. Nature 226, 1058-9.
37. Zhu Z, Li X, Chen W, Zhao Y, Li H, Qing C (2004) Prenatal stress causes gender-dependent neuronal loss and oxidative stress in rat hippocampus. J Neurosci Res 78, 837-44.