ApoER2 and VLDLr Are Required for Mediating Reelin Signalling Pathway for Normal Migration and Positioning of Mesencephalic Dopaminergic Neurons

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Sharaf, Ahmed ^a   Bock, Hans H ^a   Spittau, Björn ^a   Bouché, Elisabeth ^a   Krieglstein, Kerstin ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN DAB 1; LIPOPROTEIN RECEPTOR; LIPOPROTEIN RECEPTOR APOER2; REELIN; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL POSITIONING; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; MALE; MESENCEPHALON; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; REELIN SIGNALING PATHWAY; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA PARS COMPACTA; VENTRAL TEGMENTUM;

ANIMALS; CELL ADHESION MOLECULES, NEURONAL; CELL MOVEMENT; DOPAMINERGIC NEURONS; EMBRYO, MAMMALIAN; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; LDL-RECEPTOR RELATED PROTEINS; MALE; MESENCEPHALON; MICE; MICE, KNOCKOUT; MUTATION; NERVE TISSUE PROTEINS; PHENOTYPE; RECEPTORS, LDL; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION;

EID: 84881576811     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071091     Document Type: Article

References (38)

1. Specht LA, Pickel VM, Joh TH, Reis DJ, (1981) Fine structure of the nigrostriatal anlage in fetal rat brain by immunocytochemical localization of tyrosine hydroxylase. Brain Res 218: 49-65.
2. Kawano H, Ohyama K, Kawamura K, Nagatsu I, (1995) Migration of dopaminergic neurons in the embryonic mesencephalon of mice. Brain Res Dev Brain Res 86: 101-113.
3. Dahlström A, Fuxe K, (1964) Localization of monoamines in the lower brain stem. Experientia 20: 398-399.
4. Marchand R, Poirier LJ, (1983) Isthmic origin of neurons of the rat substantia nigra. Neuroscience 9: 373-381.
5. Riddle R, Pollock JD, (2003) Making connections: the development of mesencephalic dopaminergic neurons. Brain Res Dev Brain Res 147: 3-21.
6. Ohyama K, Kawano H, Asou H, Fukuda T, Oohira A, et al. (1998) Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice. Brain Res Dev Brain Res 107: 219-226.
7. Kang W-Y, Kim S-S, Cho S-K, Kim S, Suh-Kim H, et al. (2010) Migratory defect of mesencephalic dopaminergic neurons in developing reeler mice. Anat Cell Biol 43: 241-251.
8. Shults CW, Hashimoto R, Brady RM, Gage FH, (1990) Dopaminergic cells align along radial glia in the developing mesencephalon of the rat. Neuroscience 38: 427-436.
9. Demyanenko GP, Shibata Y, Maness PF, (2001) Altered distribution of dopaminergic neurons in the brain of L1 null mice. Brain Res Dev Brain Res 126: 21-30.
10. D'Arcangelo G, Homayouni R, Keshvara L, Rice DS, Sheldon M, et al. (1999) Reelin is a ligand for lipoprotein receptors. Neuron 24: 471-479.
11. Hiesberger T, Trommsdorff M, Howell BW, Goffinet A, Mumby MC, et al. (1999) Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron 24: 481-489.
12. Curran T, D'Arcangelo G, (1998) Role of reelin in the control of brain development. Brain Res Brain Res Rev 26: 285-294.
13. Frotscher M, (1998) Cajal-Retzius cells, Reelin, and the formation of layers. Curr Opin Neurobiol 8: 570-575.
14. Tissir F, Goffinet AM, (2003) Reelin and brain development. Nat Rev Neurosci 4: 496-505 doi:10.1038/nrn1113.
15. Soriano E, Del Río JA, (2005) The cells of cajal-retzius: still a mystery one century after. Neuron 46: 389-394.
16. Förster E, Jossin Y, Zhao S, Chai X, Frotscher M, et al. (2006) Recent progress in understanding the role of Reelin in radial neuronal migration, with specific emphasis on the dentate gyrus. Eur J Neurosci 23: 901-909.
17. Niu S, Renfro A, Quattrocchi CC, Sheldon M, D'Arcangelo G, (2004) Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway. Neuron 41: 71-84.
18. Arnaud L, Ballif BA, Förster E, Cooper JA, (2003) Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol 13: 9-17.
19. Bock HH, Herz J, (2003) Reelin activates SRC family tyrosine kinases in neurons. Curr Biol 13: 18-26.
20. Jossin Y, Ignatova N, Hiesberger T, Herz J, Lambert de Rouvroit C, et al. (2004) The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development. J Neurosci 24: 514-521.
21. Förster E, Tielsch A, Saum B, Weiss KH, Johanssen C, et al. (2002) Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus. Proc Natl Acad Sci USA 99: 13178-13183.
22. Howell BW, Hawkes R, Soriano P, Cooper JA, (1997) Neuronal position in the developing brain is regulated by mouse disabled-1. Nature 389: 733-737.
23. Trommsdorff M, Gotthardt M, Hiesberger T, Shelton J, Stockinger W, et al. (1999) Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell 97: 689-701.
24. Frykman PK, Brown MS, Yamamoto T, Goldstein JL, Herz J, (1995) Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor. Proc Natl Acad Sci USA 92: 8453-8457.
25. Oberle S, Schober A, Meyer V, Holtmann B, Henderson C, et al. (2006) Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. J Neurosci 26: 1823-1832.
26. Sauer H, Rosenblad C, Björklund A, (1995) Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc Natl Acad Sci USA 92: 8935-8939.
27. Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Møller A, et al. (1988) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96: 379-394.
28. Rogers J, Mastroeni D, Leonard B, Joyce J, Grover A, (2007) Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder? Int Rev Neurobiol 82: 235-246.
29. Nishikawa S, Goto S, Yamada K, Hamasaki T, Ushio Y, (2003) Lack of Reelin causes malpositioning of nigral dopaminergic neurons: evidence from comparison of normal and Reln(rl) mutant mice. J Comp Neurol 461: 166-173.
30. Drakew A, Deller T, Heimrich B, Gebhardt C, Del Turco D, et al. (2002) Dentate granule cells in reeler mutants and VLDLR and ApoER2 knockout mice. Exp Neurol 176: 12-24.
31. Kornack DR, Rakic P, (1995) Radial and horizontal deployment of clonally related cells in the primate neocortex: relationship to distinct mitotic lineages. Neuron 15: 311-321.
32. Komuro H, Rakic P, (1998) Distinct modes of neuronal migration in different domains of developing cerebellar cortex. J Neurosci 18: 1478-1490.
33. Pearlman AL, Faust PL, Hatten ME, Brunstrom JE, (1998) New directions for neuronal migration. Curr Opin Neurobiol 8: 45-54.
34. Won SJ, Kim SH, Xie L, Wang Y, Mao XO, et al. (2006) Reelin-deficient mice show impaired neurogenesis and increased stroke size. Exp Neurol 198: 250-259.
35. Zhao S, Chai X, Frotscher M, (2007) Balance between neurogenesis and gliogenesis in the adult hippocampus: role for reelin. Dev Neurosci 29: 84-90.
36. Herz J, Bock HH, (2002) Lipoprotein receptors in the nervous system. Annu Rev Biochem 71: 405-434.
37. Rice DS, Curran T, (2001) Role of the reelin signaling pathway in central nervous system development. Annu Rev Neurosci 24: 1005-1039.
38. Rossel M, Loulier K, Feuillet C, Alonso S, Carroll P, (2005) Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons. Development 132: 1175-1185.