메뉴 건너뛰기




Volumn 13, Issue 4, 2014, Pages 249-261

An update on disease modifying antirheumatic drugs

Author keywords

Arthritis; Biological DMARDs; Disease modifying antirheumatic drugs; IL 1; Non biologic DMARDs; TNF

Indexed keywords

ABATACEPT; ADALIMUMAB; AUROTHIOGLUCOSE; AZATHIOPRINE; CATHEPSIN; CORTICOSTEROID; CYCLOSPORIN A; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ENTERACEPT; GLYCOSIDASE INHIBITOR; GOLIMUMAB; HYDROXYCHLOROQUINE; INFLIXIMAB; INTERLEUKIN 1; INTERLEUKIN 6; LEFLUNOMIDE; METHOTREXATE; MINOCYCLINE; PENICILLAMINE; SALAZOSULFAPYRIDINE; TOCLIZUMAB; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG; ANTIRHEUMATIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84923019971     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152811304140915152102     Document Type: Article
Times cited : (42)

References (88)
  • 1
    • 84989160905 scopus 로고    scopus 로고
    • accessed on Aug 17
    • http://www.webmd.com/rheumatoid-arthritis/guide/dmardrheumatoid-arthritis-treatment (accessed on Aug 17, 2013).
    • (2013)
  • 2
    • 84989173155 scopus 로고    scopus 로고
    • accessed on Aug 20
    • http://www.webmd.com/rheumatoid-arthritis/guide/dmardrheumatoid-arthritis-treatment (accessed on Aug 20, 2013).
    • (2013)
  • 3
    • 4243572625 scopus 로고    scopus 로고
    • Current and future management approaches for rheumatoid arthritis
    • Ferdinand, B. Current and future management approaches for rheumatoid arthritis. Arthritis Res., 2002, 4(2), S16-S21.
    • (2002) Arthritis Res , vol.4 , Issue.2 , pp. S16-S21
    • Ferdinand, B.1
  • 4
    • 84867736493 scopus 로고    scopus 로고
    • The trends of DMARDS prescribed in rheumatoid arthritis patients in Malaysia
    • Sulaiman, W.; Toib, A.; Chandrashekhar, G.; Arshad, A. The trends of DMARDS prescribed in rheumatoid arthritis patients in Malaysia. Oman. Med. J., 2009, 24(4), 260-266.
    • (2009) Oman. Med. J , vol.24 , Issue.4 , pp. 260-266
    • Sulaiman, W.1    Toib, A.2    Chandrashekhar, G.3    Arshad, A.4
  • 5
    • 67650093218 scopus 로고    scopus 로고
    • The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo
    • Kremer, J.M.; Bloom, B.J.; Breedveld, F.C. The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum., 2009, 60, 1895-1905.
    • (2009) Arthritis Rheum , vol.60 , pp. 1895-1905
    • Kremer, J.M.1    Bloom, B.J.2    Breedveld, F.C.3
  • 6
    • 79952020414 scopus 로고    scopus 로고
    • Don’t forget traditional DMARDs
    • Roy, F. Don’t forget traditional DMARDs. Rheumatology, 2011, 50(3), 429-430.
    • (2011) Rheumatology , vol.50 , Issue.3 , pp. 429-430
    • Roy, F.1
  • 7
    • 0001014921 scopus 로고
    • The Effects of Azathioprine (Imuran) on Purine Synthesis in Clinical Disorders of Purine Metabolism
    • Kelley, W.N.; Rosenbloom, F.M.; Seegmiller, J. E. The Effects of Azathioprine (Imuran) on Purine Synthesis in Clinical Disorders of Purine Metabolism. J. Clin. Invest., 1967, 46(9), 1518-1529.
    • (1967) J. Clin. Invest , vol.46 , Issue.9 , pp. 1518-1529
    • Kelley, W.N.1    Rosenbloom, F.M.2    Seegmiller, J.E.3
  • 8
    • 0035014713 scopus 로고    scopus 로고
    • Leflunomide: A novel DMARD for the treatment of rheumatoid arthritis
    • Alldred, A.; Emery, P. Leflunomide: a novel DMARD for the treatment of rheumatoid arthritis. Expert Opin. Pharmacother., 2001, 2(1), 125-137.
    • (2001) Expert Opin. Pharmacother , vol.2 , Issue.1 , pp. 125-137
    • Alldred, A.1    Emery, P.2
  • 9
    • 33847004704 scopus 로고    scopus 로고
    • Drug Insight: Resistance to methotrexate and other disease-modifying antirheumatic drugs--from bench to bedside
    • Joost, W. A.; Ben, A. D.; Rik, J. S.; Gerrit, J. Drug Insight: resistance to methotrexate and other disease-modifying antirheumatic drugs--from bench to bedside. Nat. Clin. Pract. Rheumatol., 2007, 3(1), 26-34.
    • (2007) Nat. Clin. Pract. Rheumatol , vol.3 , Issue.1 , pp. 26-34
    • Joost, W.A.1    Ben, A.D.2    Rik, J.S.3    Gerrit, J.4
  • 10
    • 34247161833 scopus 로고    scopus 로고
    • Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis
    • Kitahara, K.; Kawai, S. Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis, Curr. Opin. Rheumatol., 2007, 19(3), 238-245.
    • (2007) Curr. Opin. Rheumatol , vol.19 , Issue.3 , pp. 238-245
    • Kitahara, K.1    Kawai, S.2
  • 11
    • 48049086545 scopus 로고    scopus 로고
    • The Development of novel therapies for rheumatoid arthritis
    • Ling-dong, Q.; Geoffrey, T.; Jun, T.; Dong, W. The Development of novel therapies for rheumatoid arthritis. Expert Opin. Ther. Pat., 2008, 18(7), 723-738.
    • (2008) Expert Opin. Ther. Pat , vol.18 , Issue.7 , pp. 723-738
    • Ling-dong, Q.1    Geoffrey, T.2    Jun, T.3    Dong, W.4
  • 13
    • 33847239467 scopus 로고    scopus 로고
    • PI3K delta and PI3K gamma: Partners in crime in inflammation in rheumatoid arthritis and beyond?
    • Rommel, C.; Camps, M.; Ji, H. PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond? Nat. Rev., 2007, 7(3), 191-201.
    • (2007) Nat. Rev , vol.7 , Issue.3 , pp. 191-201
    • Rommel, C.1    Camps, M.2    Ji, H.3
  • 14
    • 0029965452 scopus 로고    scopus 로고
    • Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction
    • Wymann, M. P.; Bulgarelli-Leva, G.; Zvelebil, M. J.; Pirola, L.; Vanhaesebroeck, B.; Waterfield, M.D. Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction. Mol. Cell Biol., 1996, 16(4), 1722-1733.
    • (1996) Mol. Cell Biol , vol.16 , Issue.4 , pp. 1722-1733
    • Wymann, M.P.1    Bulgarelli-Leva, G.2    Zvelebil, M.J.3    Pirola, L.4    Vanhaesebroeck, B.5    Waterfield, M.D.6
  • 15
    • 84893092808 scopus 로고    scopus 로고
    • Novel dual phosphoinositide 3-kinase-δ, γ inhibitor: Potent antiinflammatory effects and joint protection in models of rheumatoid arthritis
    • Boyle, D. L.; Kim, H. R.; Topolewski, K.; Beatrix, B.; Gary, S. F. Novel dual phosphoinositide 3-kinase-δ, γ inhibitor: Potent antiinflammatory effects and joint protection in models of rheumatoid arthritis. J. Pharmacol. Exp. Ther., 2014, 348(2), 271-280.
    • (2014) J. Pharmacol. Exp. Ther , vol.348 , Issue.2 , pp. 271-280
    • Boyle, D.L.1    Kim, H.R.2    Topolewski, K.3    Beatrix, B.4    Gary, S.F.5
  • 16
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitors in connective tissue remodeling
    • Woessner, J. F. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J., 1991, 5, 2145-2154.
    • (1991) FASEB J , vol.5 , pp. 2145-2154
    • Woessner, J.F.1
  • 17
    • 4243446177 scopus 로고
    • The imbalance between the synthesis level of metalloproteinases and TIMPs in osteoarthritic and rheumatoid arthritis cartilage can be enhanced by interleukin-1
    • Martel-Pelletier, J.; Fujimoto, N.; Obata, K.; Cloutier, J. M.; Pelletier, J. P. The imbalance between the synthesis level of metalloproteinases and TIMPs in osteoarthritic and rheumatoid arthritis cartilage can be enhanced by interleukin-1. Arthritis Rheum., 1993, 36(9), S191-S192.
    • (1993) Arthritis Rheum , vol.36 , Issue.9 , pp. S191-S192
    • Martel-Pelletier, J.1    Fujimoto, N.2    Obata, K.3    Cloutier, J.M.4    Pelletier, J.P.5
  • 18
    • 0033663810 scopus 로고    scopus 로고
    • Serum matrix metalloproteinase 3 in early rheumatoid arthritis is correlated with disease activity and radiological progression
    • Posthumus, M.D.; Limburg, P.C.; Westra, J.; van Leeuwen, M. A.; van Rijswijk, M. H. Serum matrix metalloproteinase 3 in early rheumatoid arthritis is correlated with disease activity and radiological progression. J. Rheumatol., 2000, 27, 2761-2768.
    • (2000) J. Rheumatol , vol.27 , pp. 2761-2768
    • Posthumus, M.D.1    Limburg, P.C.2    Westra, J.3    van Leeuwen, M.A.4    van Rijswijk, M.H.5
  • 19
    • 0034770450 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors in rheumatic diseases
    • Close, D. R. Matrix metalloproteinase inhibitors in rheumatic diseases. Ann. Rheum. Dis., 2001, 60(3), 62-67.
    • (2001) Ann. Rheum. Dis , vol.60 , Issue.3 , pp. 62-67
    • Close, D.R.1
  • 20
    • 0035029020 scopus 로고    scopus 로고
    • Selective matrix metalloproteinase (MMP) inhibition in rheumatoid arthritis--targetting gelatinase A activation
    • Jackson, C.; Nguyen, M.; Arkell.; Sambrook, P. Selective matrix metalloproteinase (MMP) inhibition in rheumatoid arthritis--targetting gelatinase A activation. Inflamm. Res., 2001, 50(4), 183-186.
    • (2001) Inflamm. Res , vol.50 , Issue.4 , pp. 183-186
    • Jackson, C.1    Nguyen, M.2    Arkell, S.P.3
  • 21
    • 0030839472 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition as a novel anticancer strategy: A review with special focus on batimastat and marimastat
    • Rasmussen, H. S.; McCann, P. P. Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat. Pharmacol. Ther., 1997, 75, 69-75.
    • (1997) Pharmacol. Ther , vol.75 , pp. 69-75
    • Rasmussen, H.S.1    McCann, P.P.2
  • 23
    • 33847619307 scopus 로고    scopus 로고
    • Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S
    • Weidauer, E.; Yasuda, Y.; Biswal, B. K.; Cherny, M.; James, M. N.; Bromme, D. Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S. Biol. Chem., 2007, 388(3), 331-336.
    • (2007) Biol. Chem , vol.388 , Issue.3 , pp. 331-336
    • Weidauer, E.1    Yasuda, Y.2    Biswal, B.K.3    Cherny, M.4    James, M.N.5    Bromme, D.6
  • 24
    • 0034132379 scopus 로고    scopus 로고
    • Cathepsins B and L in synovial fluids from patients with rheumatoid arthritis and the effect of cathepsin B on the activation of pro-urokinase
    • Ikeda, Y.; Ikata, T.; Mishiro, T.; Nakano, S.; Ikebe, M.; Yasuoka, S. Cathepsins B and L in synovial fluids from patients with rheumatoid arthritis and the effect of cathepsin B on the activation of pro-urokinase. J. Med. Invest., 2000, 47(1-2), 61-75.
    • (2000) J. Med. Invest , vol.47 , Issue.1-2 , pp. 61-75
    • Ikeda, Y.1    Ikata, T.2    Mishiro, T.3    Nakano, S.4    Ikebe, M.5    Yasuoka, S.6
  • 25
    • 18544405188 scopus 로고
    • Topographical differences in the content and composition of glycosaminoglycans of patellar cartilage
    • Popko, J.; Mnich, Z.; Kilczewska, D.; Trembaczowski, E. Topographical differences in the content and composition of glycosaminoglycans of patellar cartilage. Reumatologia, 1983, 21, 129-133.
    • (1983) Reumatologia , vol.21 , pp. 129-133
    • Popko, J.1    Mnich, Z.2    Kilczewska, D.3    Trembaczowski, E.4
  • 26
    • 0015444246 scopus 로고
    • Synovial fluid glycosidase activity
    • Bruce, A.B. Synovial fluid glycosidase activity. Scand J. Rheumatol., 1972, 1(2), 69-74.
    • (1972) Scand J. Rheumatol , vol.1 , Issue.2 , pp. 69-74
    • Bruce, A.B.1
  • 27
    • 0041571730 scopus 로고    scopus 로고
    • Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion
    • Zsuzsanna, O.; Anna, P.; Bela, G.; Pal, G.; Tamas, L. Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion. Arthritis Rheum., 2003, 48(8), 2163-2172.
    • (2003) Arthritis Rheum , vol.48 , Issue.8 , pp. 2163-2172
    • Zsuzsanna, O.1    Anna, P.2    Bela, G.3    Pal, G.4    Tamas, L.5
  • 28
    • 0034933712 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of methotrexate in rheumatoid arthritis
    • Cutolo, M.; Sulli, A.; Pizzorni, C.; Seriolo, B. Anti-inflammatory mechanisms of methotrexate in rheumatoid arthritis. Ann. Rheum. Dis., 2001, 60, 729-735.
    • (2001) Ann. Rheum. Dis , vol.60 , pp. 729-735
    • Cutolo, M.1    Sulli, A.2    Pizzorni, C.3    Seriolo, B.4
  • 29
    • 0037207972 scopus 로고    scopus 로고
    • Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68
    • Montesinos, M.; Desai, A.; Delano, D. Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68. Arthritis Rheum., 2003, 48(1), 240-247.
    • (2003) Arthritis Rheum , vol.48 , Issue.1 , pp. 240-247
    • Montesinos, M.1    Desai, A.2    Delano, D.3
  • 30
    • 38449094689 scopus 로고    scopus 로고
    • Understanding the mechanisms of action of methotrexate implications for the treatment of rheumatoid arthritis
    • Henghe, T.; Bruce, N. C. Understanding the mechanisms of action of methotrexate implications for the treatment of rheumatoid arthritis. Bull. NYU Hosp. Joint Dis., 2007, 65(3), 168-173.
    • (2007) Bull. NYU Hosp. Joint Dis , vol.65 , Issue.3 , pp. 168-173
    • Henghe, T.1    Bruce, N.C.2
  • 31
    • 0035985787 scopus 로고    scopus 로고
    • Molecular action of Methotrexate in inflammatory disease
    • Chan, E. S.; Cronstein B. N. Molecular action of Methotrexate in inflammatory disease. Arthritis Res., 2001, 4(4), 266-273.
    • (2001) Arthritis Res , vol.4 , Issue.4 , pp. 266-273
    • Chan, E.S.1    Cronstein, B.N.2
  • 32
    • 0042928288 scopus 로고    scopus 로고
    • Pharmacological treatment of established rheumatoid arthritis. Best
    • Lee, S.; Kavanaugh, A. Pharmacological treatment of established rheumatoid arthritis. Best Pract. Res. Clin. Rheumatol., 2003, 17(5), 811-829.
    • (2003) Pract. Res. Clin. Rheumatol , vol.17 , Issue.5 , pp. 811-829
    • Lee, S.1    Kavanaugh, A.2
  • 33
    • 84989188733 scopus 로고    scopus 로고
    • accessed on Nov 23
    • http://www.rheumatology.org/Practice/Clinical/Patients/Medications/Sulfasalazine_(Azulfidine) (accessed on Nov 23, 2013).
    • (2013)
  • 34
    • 0028998289 scopus 로고
    • Sulfasalazine. A review of its pharmacological properties and therapeutic efficacy in the treatment of rheumatoid arthritis
    • Rains, C.; Noble, S.; Faulds, D. Sulfasalazine. A review of its pharmacological properties and therapeutic efficacy in the treatment of rheumatoid arthritis. Drugs, 1995, 50(1), 137-156.
    • (1995) Drugs , vol.50 , Issue.1 , pp. 137-156
    • Rains, C.1    Noble, S.2    Faulds, D.3
  • 35
    • 84989164938 scopus 로고    scopus 로고
    • accessed on Nov 26, 2013
    • http://www.drugs.com/monograph/sulfasalazine.html (accessed on Nov 26, 2013).
  • 36
    • 84989170302 scopus 로고    scopus 로고
    • accessed on Dec 10
    • http://www.medsafe.govt.nz/profs/datasheet/s/SalazopyrintabENtab.pdf (accessed on Dec 10, 2013).
    • (2013)
  • 37
    • 84989193104 scopus 로고    scopus 로고
    • accessed on Dec 15
    • http://www.medsafe.govt.nz/profs/datasheet/s/SalazopyrintabENtab.pdf (accessed on Dec 15, 2013).
    • (2013)
  • 38
    • 84989159955 scopus 로고    scopus 로고
    • accessed on Dec 20
    • http://www.drugs.com/monograph/sulfasalazine.html (accessed on Dec 20, 2013).
    • (2013)
  • 39
    • 3042551818 scopus 로고    scopus 로고
    • 5th ed.; Elsevier: Mosby
    • Hochberg, M. C. Rheumatology, 5th ed.; Elsevier: Mosby, 2010, pp. 2384.
    • (2010) Rheumatology , pp. 2384
    • Hochberg, M.C.1
  • 41
    • 4043114982 scopus 로고    scopus 로고
    • Leflunomide: A novel disease modifying antirheumatic drug
    • Kale, V.; Bichile, L. Leflunomide: A novel disease modifying antirheumatic drug. J. Postgrad. Med., 2004, 50(2), 154-157.
    • (2004) J. Postgrad. Med , vol.50 , Issue.2 , pp. 154-157
    • Kale, V.1    Bichile, L.2
  • 42
    • 39149119330 scopus 로고    scopus 로고
    • Anti-inflammatory Activity and Structure-activity relationships of 2-hydroxy-N-(alkylphenyl)nicotinamides
    • Chien-Ming, H.; Yong-Hong, H.; Wen-Hsin, H.; An-Rong L. Anti-inflammatory Activity and Structure-activity relationships of 2-hydroxy-N-(alkylphenyl)nicotinamides. Taiwan Pharmaceut. J., 2007, 59, 105-112.
    • (2007) Taiwan Pharmaceut. J , vol.59 , pp. 105-112
    • Chien-Ming, H.1    Yong-Hong, H.2    Wen-Hsin, H.3    An-Rong, L.4
  • 43
    • 0035795893 scopus 로고    scopus 로고
    • The controversial early history of cyclosporin
    • Heusler, K.; Pletscher, A. The controversial early history of cyclosporin. Swiss Med. Wkly, 2001, 131, 299-302.
    • (2001) Swiss Med. Wkly , vol.131 , pp. 299-302
    • Heusler, K.1    Pletscher, A.2
  • 44
    • 0027429974 scopus 로고
    • Mechanisms of action of cyclosporin A in animal models of rheumatoid arthritis
    • Wong, R. Mechanisms of action of cyclosporin A in animal models of rheumatoid arthritis. Inflammopharmacol, 1993, 2, 177-195.
    • (1993) Inflammopharmacol , vol.2 , pp. 177-195
    • Wong, R.1
  • 45
    • 0027174992 scopus 로고
    • Cyclosporin clinical pharmacokinetics
    • Fahr, A. Cyclosporin clinical pharmacokinetics. Clin. Pharmacokinet., 1993, 24(6), 472-495.
    • (1993) Clin. Pharmacokinet , vol.24 , Issue.6 , pp. 472-495
    • Fahr, A.1
  • 47
    • 0030052834 scopus 로고    scopus 로고
    • Human gelatinase B, a marker enzyme in rheumatoid arthritis, is inhibited by D-penicillamine: Anti-rheumatic activity by protease inhibition
    • Norga, K.; Grillet, B.; Masure, S; Paemen, L.; Opdenakker, G. Human gelatinase B, a marker enzyme in rheumatoid arthritis, is inhibited by D-penicillamine: Anti-rheumatic activity by protease inhibition. Clin. Rheumatol., 1996, 15(1), 31-34.
    • (1996) Clin. Rheumatol , vol.15 , Issue.1 , pp. 31-34
    • Norga, K.1    Grillet, B.2    Masure, S.3    Paemen, L.4    Opdenakker, G.5
  • 48
    • 84989207151 scopus 로고    scopus 로고
    • Review of Disease_modifying anti rheumatic drugs in paediatric rheumatic disease: Eighteenth expert committee on the selection and use of essential medicines
    • Australia, 21-25 Mar
    • Gowdie, P. Review of Disease_modifying anti rheumatic drugs in paediatric rheumatic disease: Eighteenth expert committee on the selection and use of essential medicines, Royal Children’s Hospital Melbourne, Australia, 21-25 Mar 2011.
    • (2011) Royal Children’s Hospital Melbourne
    • Gowdie, P.1
  • 49
    • 70449625015 scopus 로고    scopus 로고
    • Role of toll like receptors in rheumatoid arthritis
    • Qi-Quan, H.; Richard, M. P. Role of toll like receptors in rheumatoid arthritis. Curr. Rheumatol. Rep., 2009, 11(5), 357-364.
    • (2009) Curr. Rheumatol. Rep , vol.11 , Issue.5 , pp. 357-364
    • Qi-Quan, H.1    Richard, M.P.2
  • 50
    • 0027434905 scopus 로고
    • Mechanism of action of hydroxychloroquine as an antirheumatic drug
    • Fox, R. I. Mechanism of action of hydroxychloroquine as an antirheumatic drug. Semin. Arthritis Rheum., 1993, 23,82-91.
    • (1993) Semin. Arthritis Rheum , vol.23 , pp. 82-91
    • Fox, R.I.1
  • 51
    • 0029951024 scopus 로고    scopus 로고
    • Pharmacokinetics of hydroxychloroquine and chloroquine during treatment of rheumatic diseases
    • Furst, D. E. Pharmacokinetics of hydroxychloroquine and chloroquine during treatment of rheumatic diseases. Lupus, 1996, 5(1), S11-15.
    • (1996) Lupus , vol.5 , Issue.1 , pp. S11-S15
    • Furst, D.E.1
  • 52
    • 0028235352 scopus 로고
    • Disposition and absorption of hydroxychloroquine enantiomers following a single dose of the racemate
    • McLachlan, A.; Tett, S.; Cutler, D.; Day, R. Disposition and absorption of hydroxychloroquine enantiomers following a single dose of the racemate. Chirality, 1994, 6(4), 360-364.
    • (1994) Chirality , vol.6 , Issue.4 , pp. 360-364
    • McLachlan, A.1    Tett, S.2    Cutler, D.3    Day, R.4
  • 53
    • 0024320253 scopus 로고
    • Bioavailability of hydroxychloroquine tablets in healthy volunteers
    • Tett, S. E.; Cutler, D.J.; Day, R. O.; Brown, K, F. Bioavailability of hydroxychloroquine tablets in healthy volunteers. Br. J. Clin. Pharmacol., 1989, 27(6), 771-779.
    • (1989) Br. J. Clin. Pharmacol , vol.27 , Issue.6 , pp. 771-779
    • Tett, S.E.1    Cutler, D.J.2    Day, R.O.3    Brown, K.F.4
  • 54
    • 77950649392 scopus 로고    scopus 로고
    • Enantioselective metabolism of hydroxychloroquine employing rats and mice hepatic microsomes
    • Carmem, D. C.; Pierina, S. B. Enantioselective metabolism of hydroxychloroquine employing rats and mice hepatic microsomes. Brazilian J. Pharm. Sci., 2009, 45(4), 659-667.
    • (2009) Brazilian J. Pharm. Sci , vol.45 , Issue.4 , pp. 659-667
    • Carmem, D.C.1    Pierina, S.B.2
  • 55
    • 0026352459 scopus 로고
    • Steady-state pharmacokinetics of hydroxychloroquine in rheumatoid arthritis patients
    • Miller, D. R.; Khalil, S. K.; Nygard, G. A. Steady-state pharmacokinetics of hydroxychloroquine in rheumatoid arthritis patients. DICP, 1991, 25(12), 1302-1305.
    • (1991) DICP , vol.25 , Issue.12 , pp. 1302-1305
    • Miller, D.R.1    Khalil, S.K.2    Nygard, G.A.3
  • 56
    • 34247146861 scopus 로고    scopus 로고
    • Review of eight pharmacoeconomic studies of the value of biologic dmards (adalimumab, etanercept, and infliximab) in the management of rheumatoid arthritis
    • Doan, Q. V.; Chiou, C. F.; Dubois, R. W. Review of eight pharmacoeconomic studies of the value of biologic dmards (adalimumab, etanercept, and infliximab) in the management of rheumatoid arthritis. J. Manag. Care Pharm., 2006, 12(7), 555-569.
    • (2006) J. Manag. Care Pharm , vol.12 , Issue.7 , pp. 555-569
    • Doan, Q.V.1    Chiou, C.F.2    Dubois, R.W.3
  • 57
    • 0038047917 scopus 로고    scopus 로고
    • How does infliximab work in rheumatoid arthritis?
    • Maini, R. N.; Feldmann, M. How does infliximab work in rheumatoid arthritis?. Arthritis Res., 2002, 4(2), S22-S28.
    • (2002) Arthritis Res , vol.4 , Issue.2 , pp. S22-S28
    • Maini, R.N.1    Feldmann, M.2
  • 58
    • 34447318083 scopus 로고    scopus 로고
    • The efficacy of inhibiting tumour necrosis factor α and interleukin 1 in patients with rheumatoid arthritis: A meta-analysis and adjusted indirect comparisons
    • Bansback, N.; Brennan, A. The efficacy of inhibiting tumour necrosis factor α and interleukin 1 in patients with rheumatoid arthritis: a meta-analysis and adjusted indirect comparisons. Rheumatol., 2007, 46(7), 1140-1147.
    • (2007) Rheumatol , vol.46 , Issue.7 , pp. 1140-1147
    • Bansback, N.1    Brennan, A.2
  • 59
    • 0025087855 scopus 로고
    • Interleukin 6 and its receptor in the immune response and hematopoiesis
    • Hirano, T.; Taga, T.; Matsuda, T. Interleukin 6 and its receptor in the immune response and hematopoiesis. Int. J. Cell Cloning, 1990, 8(1), 155-166.
    • (1990) Int. J. Cell Cloning , vol.8 , Issue.1 , pp. 155-166
    • Hirano, T.1    Taga, T.2    Matsuda, T.3
  • 60
    • 34548156318 scopus 로고    scopus 로고
    • Selection of one of the TNF blockers; infliximab and Etanercept
    • Mimura, T. Selection of one of the TNF blockers; infliximab and Etanercept. Nihon Rinsho, 2007, 65(7), 1282-1286.
    • (2007) Nihon Rinsho , vol.65 , Issue.7 , pp. 1282-1286
    • Mimura, T.1
  • 63
    • 0031810231 scopus 로고    scopus 로고
    • Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor α and interleukin-1in rheumatoid arthritis
    • Paleolog, E. M.; Young, S.; Stark, A. C.; McCloskey, R. V.; Feldmann, M.; Maini, R. N; Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor α and interleukin-1in rheumatoid arthritis. Arthritis Rheum., 1998, 41, 1258-1265.
    • (1998) Arthritis Rheum , vol.41 , pp. 1258-1265
    • Paleolog, E.M.1    Young, S.2    Stark, A.C.3    McCloskey, R.V.4    Feldmann, M.5    Maini, R.N.6
  • 64
    • 0042925466 scopus 로고    scopus 로고
    • Infliximab treatment of rheumatoid arthritis and Crohn’s disease
    • Nahar, I. K.; Shojania, K.; Marra, C. A.; Alamgir, A. H.; Anis, A. H. Infliximab treatment of rheumatoid arthritis and Crohn’s disease. Ann. Pharmacother., 2003, 37(9), 1256-1265.
    • (2003) Ann. Pharmacother , vol.37 , Issue.9 , pp. 1256-1265
    • Nahar, I.K.1    Shojania, K.2    Marra, C.A.3    Alamgir, A.H.4    Anis, A.H.5
  • 65
    • 16344390779 scopus 로고    scopus 로고
    • Clinical efficacy of infliximab plus methotrexate in DMARD naive and DMARD refractory rheumatoid arthritis is associated with decreased synovial expression of TNFα and IL18 but not CXCL12
    • Oosterhout, M. V.; Levarht, E. N.; Sont, J. K.; Huizinga T. W.; Toes, R. E.; Van, J. M. Clinical efficacy of infliximab plus methotrexate in DMARD naive and DMARD refractory rheumatoid arthritis is associated with decreased synovial expression of TNFα and IL18 but not CXCL12. Ann. Rheum. Dis., 2005, 64, 537-543.
    • (2005) Ann. Rheum. Dis , vol.64 , pp. 537-543
    • Oosterhout, M.V.1    Levarht, E.N.2    Sont, J.K.3    Huizinga, T.W.4    Toes, R.E.5    Van, J.M.6
  • 66
    • 79955073981 scopus 로고    scopus 로고
    • Intra-articular infliximab in DMARD-resistant knee monoarthritis: Clinical and ultrasound responses
    • Sarah, L.; James, P.; Christine, H.; Patrick, K. Intra-articular infliximab in DMARD-resistant knee monoarthritis: clinical and ultrasound responses. Int. J. Clin. Rheumatol., 2011, 6(2), 231-239.
    • (2011) Int. J. Clin. Rheumatol , vol.6 , Issue.2 , pp. 231-239
    • Sarah, L.1    James, P.2    Christine, H.3    Patrick, K.4
  • 67
    • 34247628404 scopus 로고    scopus 로고
    • Etanercept in the treatment of rheumatoid arthritis
    • Boulos, H.; Vivian, B. Etanercept in the treatment of rheumatoid arthritis. Ther. Clin. Risk Manag., 2007, 3(1), 99-105.
    • (2007) Ther. Clin. Risk Manag , vol.3 , Issue.1 , pp. 99-105
    • Boulos, H.1    Vivian, B.2
  • 68
    • 0000625691 scopus 로고    scopus 로고
    • Reduced cellularity and expression of adhesion molecules and cytokines after treatment with soluble human recombinant TNF receptor (p75) in RA patients
    • Verschueren, P. C.; Markusse, H.; Smeets, T.J. Reduced cellularity and expression of adhesion molecules and cytokines after treatment with soluble human recombinant TNF receptor (p75) in RA patients. Arthritis Rheum., 1999, 42(l), S197, 762.
    • (1999) Arthritis Rheum , vol.42 , Issue.l
    • Verschueren, P.C.1    Markusse, H.2    Smeets, T.J.3
  • 70
    • 84989168985 scopus 로고    scopus 로고
    • Genentech Actemra®
    • (accessed on Oct 9
    • Genentech Actemra®. Prescribing Information. http://www.gene.com/gene/products/information/actemra/pdf/pi.pdf. (accessed on Oct 9, 2013).
    • (2013) Prescribing Information
  • 71
    • 79951739491 scopus 로고    scopus 로고
    • Interleukin-6 inhibition for treatment of rheumatoid arthritis: A review of tocilizumab therapy
    • Patel, A. M.; Moreland, L.W. Interleukin-6 inhibition for treatment of rheumatoid arthritis: A review of tocilizumab therapy. Drug Des. Devel. Ther., 2010, 4, 263-278.
    • (2010) Drug Des. Devel. Ther , vol.4 , pp. 263-278
    • Patel, A.M.1    Moreland, L.W.2
  • 72
    • 79551665893 scopus 로고    scopus 로고
    • Choice of Biologic Therapy for Patients with Rheumatoid Arthritis: The Infection Perspective
    • Filip, K. Choice of Biologic Therapy for Patients with Rheumatoid Arthritis: The Infection Perspective. Curr. Rheumatol. Rev., 2011, 7(1), 77-87.
    • (2011) Curr. Rheumatol. Rev , vol.7 , Issue.1 , pp. 77-87
    • Filip, K.1
  • 73
    • 0036745041 scopus 로고    scopus 로고
    • Frequency of infection in patients with rheumatoid arthritis compared with controls: A population-based study
    • Doran, M. F.; Crowson, C. S.; Pond, G. R. Frequency of infection in patients with rheumatoid arthritis compared with controls: a population-based study. Arthritis Rheum., 2002, 46, 2287-2293.
    • (2002) Arthritis Rheum , vol.46 , pp. 2287-2293
    • Doran, M.F.1    Crowson, C.S.2    Pond, G.R.3
  • 74
    • 33748289504 scopus 로고    scopus 로고
    • Perioperative management of medications used in the treatment of rheumatoid arthritis
    • Carla, R.; Figgie, M. P.; Nestor, B. J.; Goodman, S. M. Perioperative management of medications used in the treatment of rheumatoid arthritis. HSS J., 2006, 2(2), 141-147.
    • (2006) HSS J , vol.2 , Issue.2 , pp. 141-147
    • Carla, R.1    Figgie, M.P.2    Nestor, B.J.3    Goodman, S.M.4
  • 75
    • 78649648584 scopus 로고    scopus 로고
    • Juvenile idiopathic arthritis and risk of cancer: A nationwide cohort study
    • Simard, J. F.; Neovius, M.; Hagelberg, S. Juvenile idiopathic arthritis and risk of cancer: A nationwide cohort study. Arthritis Rheum., 2010, 62(12), 3776-3782.
    • (2010) Arthritis Rheum , vol.62 , Issue.12 , pp. 3776-3782
    • Simard, J.F.1    Neovius, M.2    Hagelberg, S.3
  • 76
    • 84872200625 scopus 로고    scopus 로고
    • A case of leukoencephalopathy associated with adalimumab-treated rheumatoid arthritis and a review of literature
    • Ryu, Y. S.; Park, S. H.; Kim, J. M.; Kim, E. J.; Lee, J.; Kwok, S. K.; Ju, J.H.; Kim, H. Y. A case of leukoencephalopathy associated with adalimumab-treated rheumatoid arthritis and a review of literature. Rheumatol. Int., 2012, 32(11), 3481-3485.
    • (2012) Rheumatol. Int , vol.32 , Issue.11 , pp. 3481-3485
    • Ryu, Y.S.1    Park, S.H.2    Kim, J.M.3    Kim, E.J.4    Lee, J.5    Kwok, S.K.6    Ju, J.H.7    Kim, H.Y.8
  • 77
    • 16844372053 scopus 로고    scopus 로고
    • TNF-α, rheumatoid arthritis, and heart failure: A rheumatological dilemma
    • Sarzi-Puttini, P.; Atzeni, F.; Shoenfeld, Y.; Ferraccioli G.; TNF-α, rheumatoid arthritis, and heart failure: a rheumatological dilemma. Autoimmun. Rev., 2005, 4(3), 153-161.
    • (2005) Autoimmun. Rev , vol.4 , Issue.3 , pp. 153-161
    • Sarzi-Puttini, P.1    Atzeni, F.2    Shoenfeld, Y.3    Ferraccioli, G.4
  • 80
    • 80755182205 scopus 로고    scopus 로고
    • Lower gastrointestinal perforation in rheumatoid arthritis patients treated with conventional DMARDs or tocilizumab: A systematic literature review
    • Gout, T.; Ostor, A.J.; Nisar, M. K. Lower gastrointestinal perforation in rheumatoid arthritis patients treated with conventional DMARDs or tocilizumab: a systematic literature review. Clin. Rheumatol., 2011, 30(11), 1471-1474.
    • (2011) Clin. Rheumatol , vol.30 , Issue.11 , pp. 1471-1474
    • Gout, T.1    Ostor, A.J.2    Nisar, M.K.3
  • 81
    • 47249149102 scopus 로고    scopus 로고
    • Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs
    • Lyudmila, S. Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs. Br. J. Clin. Pharmacol., 2008, 66(2), 173-178.
    • (2008) Br. J. Clin. Pharmacol , vol.66 , Issue.2 , pp. 173-178
    • Lyudmila, S.1
  • 82
    • 84989200985 scopus 로고    scopus 로고
    • National Rheumatoid Arthritis Society
    • accessed on Nov 25
    • National Rheumatoid Arthritis Society. Combination therapy for rheumatoid arthritis. http://www.nras.org.uk/about_rheumatoid_arthritis/newly_diagnosed/which_drugs_are_used/combination_therapy_for_rheumatoid_arthritis. (accessed on Nov 25, 2013).
    • (2013) Combination therapy for rheumatoid arthritis
  • 83
    • 84989173147 scopus 로고    scopus 로고
    • accessed on Dec 29
    • http://www.medscape.org/viewarticle/560135 (accessed on Dec 29, 2013).
    • (2013)
  • 84
    • 84989205969 scopus 로고    scopus 로고
    • Systematic review of disease-modifying antirheumatic drugs for juvenile idiopathic arthritis
    • Alex, K.; Heather, M.; Remy, C.; John, W.; Gillian, S. Systematic review of disease-modifying antirheumatic drugs for juvenile idiopathic arthritis. BMC Pediatrics, 2012, 12(29), 1471-2431.
    • (2012) BMC Pediatrics , vol.12 , Issue.29 , pp. 1471-2431
    • Alex, K.1    Heather, M.2    Remy, C.3    John, W.4    Gillian, S.5
  • 86
    • 84883239965 scopus 로고    scopus 로고
    • Changes in use of disease-modifying antirheumatic drugs for rheumatoid arthritis in the United States during 1983-2009
    • Kim, S.; Yelin, E.; Tonner, C.; Solomon, D. Changes in use of disease-modifying antirheumatic drugs for rheumatoid arthritis in the United States during 1983-2009. Arthritis Care Res. (Hoboken), 2013, 65(9), 1529-1533.
    • (2013) Arthritis Care Res. (Hoboken) , vol.65 , Issue.9 , pp. 1529-1533
    • Kim, S.1    Yelin, E.2    Tonner, C.3    Solomon, D.4
  • 88
    • 36148995444 scopus 로고    scopus 로고
    • Are DMARDs effective for rheumatologic diseases besides rheumatoid arthritis?
    • Patricia, G. Are DMARDs effective for rheumatologic diseases besides rheumatoid arthritis? J. Family Pract., 2007, 56(11), 933-937.
    • (2007) J. Family Pract , vol.56 , Issue.11 , pp. 933-937
    • Patricia, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.