Radiobiological basis of SBRT and SRS

International Journal of Clinical Oncology

Volumn 19, Issue 4, 2014, Pages 570-578

  Song, Chang W ^a   Kim, Mi Sook ^b   Cho, L Chinsoo ^a   Dusenbery, Kathryn ^a   Sperduto, Paul W ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b Korea Institute of Radiation and Medical Science   (South Korea)

Author keywords

Radiobiology; SBRT SRS; Vascular damage

Indexed keywords

CYTOKINE; TUMOR ANTIGEN;

BLOOD VESSEL INJURY; CANCER CONTROL; CANCER RADIOTHERAPY; CELL DEATH; DETERIORATION; DNA STRAND BREAKAGE; HUMAN; IMMUNE RESPONSE; IONIZING RADIATION; ISCHEMIA; LINEAR QUADRATIC MODEL; MODEL; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIOBIOLOGY; REVIEW; STEREOTACTIC BODY RADIATION THERAPY; STEREOTACTIC RADIOSURGERY; TUMOR CELL; TUMOR VASCULARIZATION; VASCULAR TUMOR; ADVERSE EFFECTS; APOPTOSIS; BLOOD VESSEL; INNATE IMMUNITY; NEOPLASMS; PATHOLOGY; PROCEDURES; RADIATION DOSE FRACTIONATION; RADIATION RESPONSE; RADIOSURGERY;

APOPTOSIS; BLOOD VESSELS; DOSE FRACTIONATION; HUMANS; IMMUNITY, INNATE; NEOPLASMS; RADIATION, IONIZING; RADIOBIOLOGY; RADIOSURGERY;

EID: 84923018785     PISSN: 13419625     EISSN: 14377772     Source Type: Journal    
DOI: 10.1007/s10147-014-0717-z     Document Type: Review

References (63)

1. Nagata Y (2013) Stereotactic body radiotherapy for early stage lung cancer. Cancer Res Treat 45:155-161
2. Timmerman R, Paulus R, Galvin J et al (2010) Stereo-tactic body radiotherapy to treat medically inoperable early stage lung cancer patients. J Am Med Assoc 303(11):1070-1076
3. Folkert MR, Bilsky MH, Tom AK, et al. (2014) Outcome and toxicity for hypofractionated and single-fraction image-guided stereotactic radiosurgery for sarcomas metastasizing to the spine. Int J Radiat Oncol Biol Phys 88:1085-1091
4. Kim YJ, Cho KH, Kim JY et al (2010) Single-dose versus fractionated stereotactic radiotherapy for brain metastases. Int J Radiat Oncol Biol Phys 81:483-489
5. Jang WI, Kim MS, Bae SH et al (2013) High-dose stereotactic body radiotherapy correlates increased local control and overall survival in patients with inoperable hepatocellular carcinoma. Radiat Oncol 8:250-262
6. Cho LC, Fonteyne V, DeNeve W, et al (2012) Stereotactic body radiotherapy. In: Levitt et al SH (eds) Technical basis of radiation therapy, medical radiology. Radiation oncology. Springer, Berlin, pp 363-400
7. Sperduto PW (2003) A review of stereotactic radiosurgery in the management of brain metastases. Technol Cancer Res Treat 2:105-110
8. Fowler JF, Wolfgan AT, Fenwik JD et al (2004) A challenge to traditional radiation oncology. Int J Radiat Oncol Biol Phys 60:1241-1256 (Pubitemid 39440811)
9. Brown JM, Koong AC (2008) High-dose single-fraction radiotherapy: exploiting a new biology? Int J Radiat Oncol Biol Phys 71:324-325 (Pubitemid 351636202)
10. Brown JM, Diehn M, Loo BW (2010) Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer. Int J Radiat Oncol Biol Phys 78:323-327
11. Brown JM, Brenner DJ, Carlson DJ (2013) Does escalation, not "new biology" can account for the efficacy of stereotactic body radiation therapy with non-small cell lung cancer. Int J Radiat Oncol Biol Phys 85:1159-1160
12. Song CW, Park HJ, Griffin RJ, et al (2012) Radiobiology of stereotactic radiosurgery and stereotactic body radiation therapy. In: Levitt et al SH (eds) Technical basis of radiation therapy, medical radiology. Radiation oncology. Springer, Berlin, pp 51-61
13. Park HJ, Griffin RJ, Hui S et al (2012) Radiation-induced vascular damage in tumors: implications of vascular damage in ablative hypofractionated radiotherapy (SBRT and SRS). Radiat Res 177:311-327
14. Song CW, Cho LC, Yuan J et al (2013) Radiobiology of stereotactic body radiation therapy/stereotactic radiosurgery and the linear-quadratic mode. Int J Radiat Oncol Biol Phys 87:18-19
15. Song CW, Park I, Cho LC et al (2014) Is there indirect cell death involved in response of tumor to SRS and SBRT? Int J Radiat Oncol Biol Phys 89:924-925
16. Kirkpatrick JP, Meyer JJ, Marks LB (2008) The linear-quadratic model is appropriate to model high dose per fraction effects in radiosurgery. Semin Radiat Oncol 18:240-243
17. Kocher M, Treuer H, Voges J et al (2000) Computer simulation of cytotoxic and vascular effects of radiosurgery in solid and necrotic brain metastases. Radiother Oncol 54:149-156 (Pubitemid 30116766)
18. Brown JM, Carlson DJ, Brenner DJ (2014) The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved? Int J Radiat Oncol Bio Phys 88:254-262
19. McBride WH, Schaue D (2013) In situ tumor ablation with radiation therapy: Its effect on the tumor microenvironment and anti-tumor immunity. In: Keisari Y (eds) Tumor ablation. Springer Science + Business Media, Dordrecht
20. Finkelstein SE, Timmerman R, McBride WH et al (2011) The confluence of stereotactic ablative radiotherapy and tumor immunology. Clin Dev Immunol 2011:7-13 Article ID 439752
21. Monte UD (2009) Does the cell number 109 still really fit one gram of tumor tissue? Cell Cycle 8(3):505-506
22. Leith JT, Cook S, Choughle P et al (1994) Intrinsic and extrinsic characteristics of human tumors relevant to radiosurgery: comparative cellular radiosensivity and hypoxic percentages. Acta Neurochir Supp 62:18-27
23. Cramer W (1932) Experimental observations on the therapeutic action of radium. Tenth Sci Rep Invest Imp Cancer Research Fund, pp 95-122
24. Lasnitzki I (1947) Quantitative analysis of the direct and indirect action of X radiation on malignant cells. Br J Radiol 20:240-247
25. Merwin R, Algire GH (1950) Transparent-chamber observations of the response of transplantable mouse mammary tumor to local roentgen irradiation. J Natl Cancer Inst 2:593-623
26. Clement JJ, Tanaka N, Song CW (1978) Tumor reoxygenation and postirradiation vascular changes. Radiology 127:799-803 (Pubitemid 8339601)
27. Clement JJ, Song CW, Levitt SH (1976) Changes in functional vascularity and cell number following X-irradiation of a murine carcinoma. Int J Radiat Oncol Biol Phys 1:671-678
28. Folkman J (1985) Tumor angiogenesis. Adv Cancer Res 43:175-203
29. Hammersen F, Endrich B, Messmer K (1985) The fine structure of tumor blood vessels. I. Participation of non-endothelial cells in tumor angiogenesis. Int J Microcirc Clin Exp 4:31-43
30. Carmeliet P, Jain RK (2011) Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nature Rev 10:417-425
31. Song CW (1998) Modification of blood flow. In: Mools M, Vaupel P (eds) Blood perfusion and microenvironment of human tumors, implications for clinical radio oncology. Springer, Berlin, pp 194-207
32. Reyes M, Dudek A, Jahagirdar B et al (2002) Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 109:337-346 (Pubitemid 34141807)
33. Dewhirst MW, Cao Y, Moeller B et al (1996) The cycle between angiogenesis, perfusion, and hypoxia in tumors. In: Teicher BA (ed) Cancer drug resistance. Humana Press, Totowa, pp 3-24
34. Vaupel P, Kallinowski F, Okunieff P (1989) Blood flow, oxygenation and nutrient supply, and metabolic microenvironment of human tumors. Cancer Res 49:6449-6465 (Pubitemid 20008770)
35. Ahn JB, Rha SY, Shin SJ et al (2010) Circulating endothelial progenitor cells (EPC) for tumor vasculogenesis in gastric cancer patients. Cancer Lett 288:124-132
36. Mäntylä MJ, Toivanen JT, Pitkänen MA et al (1982) Radiationinduced changes in regional blood flow in human tumors. Int J Radiat Oncol Biol Phys 8:1711-1717 (Pubitemid 13236233)
37. Pirhonen JP, Grenman SA, Breadbacka AB et al (1995) Effects of external radiotherapy on uterine blood flow in patients with advanced cervical carcinoma assessed by color Doppler ultrasonography. Cancer 76:67-71
38. Mayr NA, Yuh WT, Magnotta VA et al (1996) Tumor perfusion studies using fast magnetic resonance imaging technique in advanced cervical cancer: a new noninvasive predictive assay. Int J Radiat Oncol Biol Phys 36:623-633 (Pubitemid 27000034)
39. Ng QS, Goh V, Milner J et al (2007) Acute tumor vascular effects following fractionated radiotherapy in human lung cancer: in vivo whole tumor assessment using volumetric perfusion computed tomography. Int J Radiat Oncol Biol Phys 67:417-424 (Pubitemid 46108337)
40. Solesvik OV, Rofstad EK, Brustad T (1984) Vascular changes in a human malignant melanoma xenograft following single-dose irradiation. Radiat Res 98:115-128 (Pubitemid 14106046)
41. Kioi M, Vogel H, Schultz G et al (2010) Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest 120:694-705
42. Rubin P, Casarett G (1966) Microcirculation of tumors Part II: the supervascularized state of irradiated regressing tumors. Clin Radiol 17:346-355
43. Song CW, Levitt SH (1970) Effect of X irradiation on vascularity of normal tissues and experimental tumor. Radiology 94:445-447
44. Song CW, Levitt SH (1971) Vascular changes in Walker 256 carcinoma of rats following x irradiation. Radiology 100:397-407
45. Song CW, Payne T, Levitt SH (1972) Vascularity and blood flow in X-irradiated Walker carcinoma 256 of rats. Radiology 104:693-697
46. Wong HH, Song CW, Levitt SH (1973) Early changes in the functional vasculature of Walker carcinoma 256 following irradiation. Radiology 108:429-434
47. Song CW, Sung JH, Clement JJ et al (1974) Vascular changes in neuroblastoma of mice following X-irradiation. Cancer Res 34:2344-2350
48. Kim DWN, Huamani J, Niemann KJ et al (2006) Noninvasive assessment of tumor vasculature response to radiation-mediated, vasculature-targeted therapy using quantified power Doppler sonography. J Ultrasound Med 25:1507-1517
49. Kaffas AE, Gilles A, Czarnota GJ (2013) Dose-dependent response of tumor vasculature to radiation therapy in combination with Sunitinib by three-dimensional high-frequency power Doppler ultrasound. Angiogenesis 16:443-454
50. Denis F, Bougnoux P, Paon L et al (2003) Radiosensitivity of rat mammary tumors correlates with early vessel changes assessed by power Doppler sonography. J Ultrasound Med 22:921-929 (Pubitemid 37082559)
51. Tsai JH, Makonnen S, Hyman T, et al. (2005) Ionizing radiation inhibits tumor neovascularization by inducing ineffective angiogenesis. Proc Am Assoc Cancer Res 46: Abstract #3032
52. Ogawa K, Boucher Y, Kashiwagi S et al (2007) Influence of tumor cell and stroma sensitivity of tumor response to radiation. Cancer Res 67:4016-4021 (Pubitemid 46815045)
53. Chen FH, Chiang CS, Wang CC et al (2009) Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors. Clin Cancer Res 15:1721-1729
54. Oh ET, Park MT, Song MJ et al (2014) Radiation-induced angiogenic signaling pathway in endothelial cells obtained from normal and cancer tissue of human breast. Oncogene 33:1229-1238
55. Garcia-Barros M, Paris F, Cordon-Cardo C et al (2003) Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 300:1155-1159 (Pubitemid 36583102)
56. Denekamp J (1984) Vascular endothelium as the vulnerable element in tumours. Acta Radiol Oncol 23:217-225
57. Lugada AA, Moran JP, Gerbe SA et al (2005) Local radiation therapy of B16 Melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J Immunol 174:7516-7523 (Pubitemid 40806254)
58. Lee Y, Auh SL, Wang Y et al (2009) Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. Blood 114:589-595
59. Matsumura S, Wang B, Kawashima N et al (2008) Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. J Immunol 181:3009-3107
60. Chiang CS, Hong JH, Stalder A et al (1997) Delayed molecular response to brain irradiation. Int J Radiat Biol 72:45-53 (Pubitemid 27316089)
61. Kaur P, Asea A (2012) Radiation-induced effects and the immune system in cancer. Front Oncol 2:10-11
62. Seung SK, Curti BD, Drittenden M et al (2012) Phase I study of stereotactic body radiotherapy and interleukin-2: tumor and immunological responses. Sci Transl Med 4:137-174
63. Shibamoto Y, Hashizume C, Baba F et al (2011) Stereotactic body radiotherapy using a radiobiology-based regimen for stage I nonsmall cell lung cancer. Cancer 118:2078-2084