Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity

European Journal of Immunology

Volumn 45, Issue 2, 2015, Pages 525-530

  Giles, James A ^a   Greenhalgh, Andrew D ^b   Davies, Claire L ^c   Denes, Adam ^a   Shaw, Tovah ^a   Coutts, Graham ^a   Rothwell, Nancy J ^a   Mccoll, Barry W ^c   Allan, Stuart M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MONTREAL GENERAL HOSPITAL   (Canada)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Innate immunity; Interleukin 1 (IL 1); Neuroinflammation; Neutrophil

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CYTOKINE RESPONSE; ENCEPHALITIS; INFECTION RESISTANCE; INFECTION SENSITIVITY; INNATE IMMUNITY; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY; ANIMAL; ANTIBODY SPECIFICITY; BRAIN; CHEMICALLY INDUCED; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; KNOCKOUT MOUSE; LUNG; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PERITONEUM; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; ENCEPHALITIS; GENE EXPRESSION REGULATION; IMMUNITY, INNATE; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LUNG; MICE; MICE, KNOCKOUT; MICROGLIA; NEUTROPHIL INFILTRATION; NEUTROPHILS; ORGAN SPECIFICITY; PERITONEUM; SIGNAL TRANSDUCTION;

EID: 84923005762     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201444748     Document Type: Article

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