LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Nagasawa, Satoi ^a,b   Sedukhina, Anna S ^a   Nakagawa, Yuko ^a,b   Maeda, Ichiro ^b   Kubota, Manabu ^b   Ohnuma, Shigeko ^b   Tsugawa, Koichiro ^b   Ohta, Tomohiko ^a   Roche Molina, Marta ^c   Bernal, Juan A ^c   Narváez, Ana J ^d   Jeyasekharan, Anand D ^e   Sato, Ko ^a  

^a ST MARIANNA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HISTONE DEMETHYLASE; LYSINE SPECIFIC HISTONE DEMETHYLASE 1; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OLAPARIB; PROGESTERONE RECEPTOR; UNCLASSIFIED DRUG; KDM1A PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR;

ADULT; AGED; ARTICLE; BASAL LIKE BREAST CANCER; BREAST CANCER; CANCER PROGNOSIS; CLINICAL ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; ENZYME INHIBITION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LSD1 GENE; PROTEIN EXPRESSION; RECURRENCE FREE SURVIVAL; TRIPLE NEGATIVE BREAST CANCER; TUMOR SUPPRESSOR GENE; BIOLOGY; BREAST NEOPLASMS; DRUG RESISTANCE; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC DATABASE; GENETICS; METABOLISM; MORTALITY; NEOPLASMS, BASAL CELL; PATHOLOGY; PROCEDURES; PROGNOSIS; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL LINE, TUMOR; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HISTONE DEMETHYLASES; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASMS, BASAL CELL; POLY(ADP-RIBOSE) POLYMERASE INHIBITORS; PROGNOSIS; RNA, MESSENGER; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84922998600     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118002     Document Type: Article

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