Characterization of DNA G-quadruplex species forming from C9ORF72 G4C2-expanded repeats associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration

Neurobiology of Aging

Volumn 36, Issue 2, 2015, Pages 1091-1096

  Šket, Primož ^a,b   Pohleven, Jure ^c   Kovanda, Anja ^c,d   Štalekar, Maja ^c   Župunski, Vera ^e   Zalar, Matja ^a   Plavec, Janez ^a,b,e   Rogelj, Boris ^c,d  

^a NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^b EN FIST Center of Excellence   (Slovenia)

^c JO EF STEFAN INSTITUTE   (Slovenia)

^d Biomedical Research Institute BRIS   (Slovenia)

^e UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Amyotrophic lateral sclerosis; Chromosome 9 open reading frame 72; Expanded hexanucleotide repeats; Frontotemporal lobar degeneration; G quadruplex

Indexed keywords

GUANINE QUADRUPLEX; C9ORF72 PROTEIN, HUMAN; DNA; PROTEIN; REPETITIVE DNA; RNA;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; C9ORF72 GENE; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA DETERMINATION; DNA SEQUENCE; DNA STRUCTURE; FRONTOTEMPORAL DEMENTIA; G4C2 REPEAT EXPANSION; GENE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC VARIABILITY; MOLECULAR PATHOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREDICTION; STRUCTURE ANALYSIS; GENETIC TRANSCRIPTION; GENETICS; HUMAN; INTRON;

AMYOTROPHIC LATERAL SCLEROSIS; CIRCULAR DICHROISM; DNA; DNA REPEAT EXPANSION; FRONTOTEMPORAL LOBAR DEGENERATION; G-QUADRUPLEXES; HUMANS; INTRONS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; RNA; TRANSCRIPTION, GENETIC;

EID: 84922813565     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.09.012     Document Type: Article

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