Development of industrial yeast strain with improved acid- and thermo-tolerance through evolution under continuous fermentation conditions followed by haploidization and mating

Journal of Bioscience and Bioengineering

Volumn 118, Issue 6, 2014, Pages 689-695

  Mitsumasu, Kanako ^a   Liu, Ze Shen ^b   Tang, Yue Qin ^b,c   Akamatsu, Takashi ^d   Taguchi, Hisataka ^d   Kida, Kenji ^c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b PEKING UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

^d SOJO UNIVERSITY   (Japan)

Author keywords

Acid tolerance; Ethanol fermentation; Evolutionary engineering; Haploidization and mating; Saccharomyces cerevisiae; Strain development; Thermo tolerance

Indexed keywords

ETHANOL; YEAST;

ACID TOLERANCE; ETHANOL FERMENTATION; EVOLUTIONARY ENGINEERING; HAPLOIDIZATION AND MATING; STRAIN DEVELOPMENT;

FERMENTATION;

ALCOHOL; ACID; SACCHAROMYCES CEREVISIAE PROTEIN;

ACCLIMATIZATION; ACID TOLERANCE; ARTICLE; BACTERIUM CONTAMINATION; BATCH FERMENTATION; CELL COUNT; CELL VIABILITY; CONTINUOUS FERMENTATION; DIPLOIDY; HAPLOIDY; HIGH TEMPERATURE; MATING; NONHUMAN; PH; PHENOTYPE; SACCHAROMYCES CEREVISIAE; DRUG EFFECTS; EVOLUTION; FERMENTATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; TEMPERATURE;

SACCHAROMYCES CEREVISIAE;

ACCLIMATIZATION; ACIDS; BIOLOGICAL EVOLUTION; ETHANOL; FERMENTATION; HAPLOIDY; HYDROGEN-ION CONCENTRATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE;

EID: 84922781835     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2014.05.012     Document Type: Article

References (23)

1. Kumar S., Singh S.P., Mishra I.M., Adhikari D.K. Recent advances in production of bioethanol from lignocellulosic biomass. Chem. Eng. Technol. 2009, 32:517-526.
2. Nevoigt E. Progress in metabolic engineering of Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 2008, 72:379-412.
3. Mira N.P., Teixeira M.C., Sa-Correia I. Adaptive response and tolerance to weak acids in Saccharomyces cerevisiae: a genome-wide view. Omics 2010, 14:525-540.
4. Zhao X.Q., Bai F.W. Mechanisms of yeast stress tolerance and its manipulation for efficient fuel ethanol production. J.Biotechnol. 2009, 144:23-30.
5. Zheng D.Q., Wu X.C., Tao X.L., Wang P.M., Li P., Chi X.Q., Li Y.D., Yan Q.F., Zhao Y.H. Screening and construction of Saccharomyces cerevisiae strains with improved multi-tolerance and bioethanol fermentation performance. Bioresour. Technol. 2011, 102:3020-3027.
6. Auesukaree C., Koedrith P., Saenpayavai P., Asvarak T., Benjaphokee S., Sugiyama M., Kaneko Y., Harashima S., Boonchird C. Characterization and gene expression profiles of thermotolerant Saccharomyces cerevisiae isolates from Thai fruits. J.Biosci. Bioeng. 2012, 114:144-149.
7. Benjaphokee S., Hasegawa D., Yokota D., Asvarak T., Auesukaree C., Sugiyama M., Kaneko Y., Boonchird C., Harashima S. Highly efficient bioethanol production by a Saccharomyces cerevisiae strain with multiple stress tolerance to high temperature, acid and ethanol. N.Biotechnol. 2012, 29:379-386.
8. de Melo H.F., Bonini B.M., Thevelein J., Simoes D.A., Morais M.A. Physiological and molecular analysis of the stress response of Saccharomyces cerevisiae imposed by strong inorganic acid with implication to industrial fermentations. J.Appl. Microbiol. 2010, 109:116-127.
9. Sant'Ana G.S., Paes L.S., Paiva A.F., Fietto L.G., Totola A.H., Tropia M.J., Silveira-Lemos D., Lucas C., Fietto J.L., Brandao R.L., Castro I.M. Protective effect of ions against cell death induced by acid stress in Saccharomyces. FEMS Yeast Res. 2009, 9:701-712.
10. Shahsavarani H., Sugiyama M., Kaneko Y., Chuenchit B., Harashima S. Superior thermotolerance of Saccharomyces cerevisiae for efficient bioethanol fermentation can be achieved by overexpression of RSP5 ubiquitin ligase. Biotechnol. Adv. 2012, 30:1289-1300.
11. Wright J., Bellissimi E., de Hulster E., Wagner A., Pronk J.T., van Maris A.J. Batch and continuous culture-based selection strategies for acetic acid tolerance in xylose-fermenting Saccharomyces cerevisiae. FEMS Yeast Res. 2011, 11:299-306.
12. Albers E., Larsson C. Acomparison of stress tolerance in YPD and industrial lignocellulose-based medium among industrial and laboratory yeast strains. J.Ind. Microbiol. Biotechnol. 2009, 36:1085-1091.
13. Borneman A.R., Desany B.A., Riches D., Affourtit J.P., Forgan A.H., Pretorius I.S., Egholm M., Chambers P.J. Whole-genome comparison reveals novel genetic elements that characterize the genome of industrial strains of Saccharomyces cerevisiae. PLoS Genet. 2011, 7:e1001287.
14. Cakar Z.P., Seker U.O., Tamerler C., Sonderegger M., Sauer U. Evolutionary engineering of multiple-stress resistant Saccharomyces cerevisiae. FEMS Yeast Res. 2005, 5:569-578.
15. Martinez-Pastor M.T., Marchler G., Schuller C., Marchler-Bauer A., Ruis H., Estruch F. The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J. 1996, 15:2227-2235.
16. An M.Z., Tang Y.Q., Mitsumasu K., Liu Z.S., Morimura S., Kida K. Enhanced thermotolerance for ethanol fermentation of Saccharomyces cerevisiae strain by overexpression of the gene coding for trehalose-6-phosphate synthase. Biotechnol. Lett. 2011, 33:1367-1374.
17. Martín C., Jönsson L.J. Comparison of the resistance of industrial and laboratory strains of Saccharomyces and Zygosaccharomyces to lignocellulose-derived fermentation inhibitors. Enzyme. Microb. Technol. 2003, 32:386-395.
18. Tang Y.Q., An M.Z., Liu K., Nagai S., Shigematsu T., Morimura S., Kida K. Ethanol production from acid hydrolysate of wood biomass using the flocculating yeast Saccharomyces cerevisiae strain KF-7. Process Biochem. 2006, 41:909-914.
19. Kida K., Kume K., Morimura S., Sonoda Y. Repeated-batch fermentation process using a thermotolerant flocculating yeast constructed by protoplast fusion. J.Ferment. Bioeng. 1992, 74:169-173.
20. Tomitaka M., Taguchi H., Matsuoka M., Morimura S., Kida K., Akamatsu T. Potent l-lactic acid assimilation of the fermentative and heterothallic haploid yeast Saccharomyces cerevisiae NAM34-4C. J.Biosci. Bioeng. 2013, 117:65-70.
21. Kida K., Morimura S., Sonoda Y. Accumulation of propionic acid during anaerobic treatment of distillery wastewater from barley-shochu making. J.Ferment. Bioeng. 1993, 75:213-216.
22. Watanabe D., Araki Y., Zhou Y., Maeya N., Akao T., Shimoi H. Aloss-of-function mutation in the PAS kinase Rim15p is related to defective quiescence entry and high fermentation rates of Saccharomyces cerevisiae sake yeast strains. Appl. Environ. Microbiol. 2012, 78:4008-4016.
23. Urbanczyk H., Noguchi C., Wu H., Watanabe D., Akao T., Takagi H., Shimoi H. Sake yeast strains have difficulty in entering a quiescent state after cell growth cessation. J.Biosci. Bioeng. 2011, 112:44-48.