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Volumn 179, Issue 3, 2015, Pages 477-484

Neonatal brain injury and systemic inflammation: Modulation by activated protein C ex vivo

Author keywords

CD11b; Neonatal encephalopathy; Protein C; Reactive oxygen intermediates; Toll like receptor 4

Indexed keywords

ACTIVATED PROTEIN C; CD11B ANTIGEN; LIPOPOLYSACCHARIDE; PROTEIN C; TOLL LIKE RECEPTOR 4; ANTICOAGULANT AGENT; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; TLR4 PROTEIN, HUMAN;

EID: 84922769051     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12453     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 0035380820 scopus 로고    scopus 로고
    • Developmental outcomes of newborn encephalopathy in the term infant
    • Badawi N, Keogh JM, Dixon G, Kurinczuk JJ. Developmental outcomes of newborn encephalopathy in the term infant. Indian J Pediatr 2001; 68:527-530.
    • (2001) Indian J Pediatr , vol.68 , pp. 527-530
    • Badawi, N.1    Keogh, J.M.2    Dixon, G.3    Kurinczuk, J.J.4
  • 2
    • 0030872032 scopus 로고    scopus 로고
    • Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1β, and tumor necrosis factor-α), neonatal brain white matter lesions, and cerebral palsy
    • Yoon BH, Jun JK, Romero R, Park KH, Gomez R, Choi JH. Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1β, and tumor necrosis factor-α), neonatal brain white matter lesions, and cerebral palsy. Am J Obstet Gynecol 1997; 177:19-26.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 19-26
    • Yoon, B.H.1    Jun, J.K.2    Romero, R.3    Park, K.H.4    Gomez, R.5    Choi, J.H.6
  • 3
    • 0031783968 scopus 로고    scopus 로고
    • Neonatal cytokines and coagulation factors in children with cerebral palsy
    • Nelson KB, Dambrosia JM, Grether JK, Phillips TM. Neonatal cytokines and coagulation factors in children with cerebral palsy. Ann Neurol 1998; 44:665-675.
    • (1998) Ann Neurol , vol.44 , pp. 665-675
    • Nelson, K.B.1    Dambrosia, J.M.2    Grether, J.K.3    Phillips, T.M.4
  • 5
    • 33744796815 scopus 로고    scopus 로고
    • Perinatal infections and cerebral palsy
    • Hermansen MC, Hermansen MG. Perinatal infections and cerebral palsy. Clin Perinatol 2006; 33:315-333.
    • (2006) Clin Perinatol , vol.33 , pp. 315-333
    • Hermansen, M.C.1    Hermansen, M.G.2
  • 8
    • 34247338117 scopus 로고    scopus 로고
    • Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms
    • McColl BW, Rothwell NJ, Allan SM. Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms. J Neurosci 2007; 27:4403-4412.
    • (2007) J Neurosci , vol.27 , pp. 4403-4412
    • McColl, B.W.1    Rothwell, N.J.2    Allan, S.M.3
  • 9
    • 7044223228 scopus 로고    scopus 로고
    • Leukocyte count predicts outcome after ischemic stroke: the Northern Manhattan Stroke Study
    • Elkind MS, Cheng J, Rundek T, Boden-Albala B, Sacco RL. Leukocyte count predicts outcome after ischemic stroke: the Northern Manhattan Stroke Study. J Stroke Cerebrovasc Dis 2004; 13:220-227.
    • (2004) J Stroke Cerebrovasc Dis , vol.13 , pp. 220-227
    • Elkind, M.S.1    Cheng, J.2    Rundek, T.3    Boden-Albala, B.4    Sacco, R.L.5
  • 10
    • 19044368763 scopus 로고    scopus 로고
    • Investigational anti-inflammatory agents for the treatment of ischemic brain injury
    • Wang X. Investigational anti-inflammatory agents for the treatment of ischemic brain injury. Expert Opin Investig Drugs 2005; 14:393-409.
    • (2005) Expert Opin Investig Drugs , vol.14 , pp. 393-409
    • Wang, X.1
  • 11
    • 53549132254 scopus 로고    scopus 로고
    • Cell adhesion molecules and ischemic stroke
    • Yilmaz G, Granger DN. Cell adhesion molecules and ischemic stroke. Neurol Res 2008; 30:783-793.
    • (2008) Neurol Res , vol.30 , pp. 783-793
    • Yilmaz, G.1    Granger, D.N.2
  • 12
    • 34249856663 scopus 로고    scopus 로고
    • Elevated total peripheral leukocyte count may identify risk for neurological disability in asphyxiated term neonates
    • Morkos AA, Hopper AO, Deming DD etal. Elevated total peripheral leukocyte count may identify risk for neurological disability in asphyxiated term neonates. J Perinatol 2007; 27:365-370.
    • (2007) J Perinatol , vol.27 , pp. 365-370
    • Morkos, A.A.1    Hopper, A.O.2    Deming, D.D.3
  • 13
    • 0030979086 scopus 로고    scopus 로고
    • The role of neutrophils in the production of hypoxic-ischemic brain injury in the neonatal rat
    • Hudome S, Palmer C, Roberts RL, Mauger D, Housman C, Towfighi J. The role of neutrophils in the production of hypoxic-ischemic brain injury in the neonatal rat. Pediatr Res 1997; 41:607-616.
    • (1997) Pediatr Res , vol.41 , pp. 607-616
    • Hudome, S.1    Palmer, C.2    Roberts, R.L.3    Mauger, D.4    Housman, C.5    Towfighi, J.6
  • 14
    • 84883660265 scopus 로고    scopus 로고
    • Inflammatory responses in hypoxic ischemic encephalopathy
    • Liu F, McCullough LD. Inflammatory responses in hypoxic ischemic encephalopathy. Acta Pharmacol Sin 2013; 34:1121-1130.
    • (2013) Acta Pharmacol Sin , vol.34 , pp. 1121-1130
    • Liu, F.1    McCullough, L.D.2
  • 15
    • 33745825956 scopus 로고    scopus 로고
    • Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, Toll-like receptor-4 and CD11b expression compared with adults
    • Molloy EJ, O'Neill AJ, Doyle BT etal. Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, Toll-like receptor-4 and CD11b expression compared with adults. Biol Neonate 2006; 90:34-39.
    • (2006) Biol Neonate , vol.90 , pp. 34-39
    • Molloy, E.J.1    O'Neill, A.J.2    Doyle, B.T.3
  • 16
    • 0038506990 scopus 로고    scopus 로고
    • Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke
    • Zhang L, Zhang ZG, Zhang RL, Lu M, Krams M, Chopp M. Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke. Stroke 2003; 34:1790-1795.
    • (2003) Stroke , vol.34 , pp. 1790-1795
    • Zhang, L.1    Zhang, Z.G.2    Zhang, R.L.3    Lu, M.4    Krams, M.5    Chopp, M.6
  • 17
    • 0036369590 scopus 로고    scopus 로고
    • Anti-leukocyte antibodies: LeukArrest (Hu23F2G) and Enlimomab (R6.5) in acute stroke
    • Becker KJ. Anti-leukocyte antibodies: LeukArrest (Hu23F2G) and Enlimomab (R6.5) in acute stroke. Curr Med Res Opin 2002; 18:18-22.
    • (2002) Curr Med Res Opin , vol.18 , pp. 18-22
    • Becker, K.J.1
  • 18
    • 34247545017 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke
    • Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Izasoation I. Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 2007; 115:1599-1608.
    • (2007) Circulation , vol.115 , pp. 1599-1608
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3    Lorenzo, P.4    Moro, M.A.5    Izasoation, I.6
  • 19
    • 0028556421 scopus 로고
    • Neutrophils, host defense, and inflammation: a double-edged sword
    • Smith JA. Neutrophils, host defense, and inflammation: a double-edged sword. J Leukoc Biol 1994; 56:672-686.
    • (1994) J Leukoc Biol , vol.56 , pp. 672-686
    • Smith, J.A.1
  • 20
    • 0026490413 scopus 로고
    • Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo
    • Kontos CD, Wei EP, Williams JI, Kontos HA, Povlishock JT. Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo. Am J Physiol 1992; 263:H1234-1242.
    • (1992) Am J Physiol , vol.263 , pp. H1234-H1242
    • Kontos, C.D.1    Wei, E.P.2    Williams, J.I.3    Kontos, H.A.4    Povlishock, J.T.5
  • 21
    • 0027992580 scopus 로고
    • Direct evidence of free radical production after ischaemia and reperfusion and protective effect of desferrioxamine: ESR and vitamin E studies
    • Defraigne JO, Detry O, Pincemail J etal. Direct evidence of free radical production after ischaemia and reperfusion and protective effect of desferrioxamine: ESR and vitamin E studies. Eur J Vasc Surg 1994; 8:537-543.
    • (1994) Eur J Vasc Surg , vol.8 , pp. 537-543
    • Defraigne, J.O.1    Detry, O.2    Pincemail, J.3
  • 22
    • 0026591793 scopus 로고
    • The protein C anticoagulant pathway
    • Esmon CT. The protein C anticoagulant pathway. Arterioscler Thromb 1992; 12:135-145.
    • (1992) Arterioscler Thromb , vol.12 , pp. 135-145
    • Esmon, C.T.1
  • 23
    • 0035826096 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Vincent JLV, Laterre PF etal. PROWESS study group. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709.
    • (2001) N Engl J Med , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.V.2    Laterre, P.F.3
  • 25
    • 34547581948 scopus 로고    scopus 로고
    • Activated protein C reduces endotoxin-induced white matter injury in the developing rat brain
    • Yesilirmak DC, Kumral A, Baskin H etal. Activated protein C reduces endotoxin-induced white matter injury in the developing rat brain. Brain Res 2007; 20:14-23.
    • (2007) Brain Res , vol.20 , pp. 14-23
    • Yesilirmak, D.C.1    Kumral, A.2    Baskin, H.3
  • 26
    • 0033615037 scopus 로고    scopus 로고
    • Measurement of the urinary lactate: creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy
    • Huang CC, Wang ST, Chang YC, Lin KP, Wu PL. Measurement of the urinary lactate: creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy. N Engl J Med 1999; 341:328-335.
    • (1999) N Engl J Med , vol.341 , pp. 328-335
    • Huang, C.C.1    Wang, S.T.2    Chang, Y.C.3    Lin, K.P.4    Wu, P.L.5
  • 27
    • 0017199855 scopus 로고
    • Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study
    • Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol 1976; 33:696-705.
    • (1976) Arch Neurol , vol.33 , pp. 696-705
    • Sarnat, H.B.1    Sarnat, M.S.2
  • 28
    • 0032231402 scopus 로고    scopus 로고
    • Prediction of neuromotor outcome in perinatal asphyxia: evaluation of MR scoring systems
    • Barkovich AJ, Hajnal BL, Vigneron D etal. Prediction of neuromotor outcome in perinatal asphyxia: evaluation of MR scoring systems. Am J Neuroradiol 1998; 19:143-149.
    • (1998) Am J Neuroradiol , vol.19 , pp. 143-149
    • Barkovich, A.J.1    Hajnal, B.L.2    Vigneron, D.3
  • 29
    • 44649103920 scopus 로고    scopus 로고
    • Activated protein C inhibits chemotaxis and interleukin-6 release by human neutrophils without affecting other neutrophil functions
    • Galley HF, El Sakka NE, Webster NR etal. Activated protein C inhibits chemotaxis and interleukin-6 release by human neutrophils without affecting other neutrophil functions. Br J Anaesth 2008; 100:815-819.
    • (2008) Br J Anaesth , vol.100 , pp. 815-819
    • Galley, H.F.1    El Sakka, N.E.2    Webster, N.R.3
  • 30
    • 0027314958 scopus 로고
    • Further characterization of the neutrophil oxidative burst by flow cytometry
    • Smith JA, Wiedemann MJ. Further characterization of the neutrophil oxidative burst by flow cytometry. J Immunol Methods 1993; 3:261-268.
    • (1993) J Immunol Methods , vol.3 , pp. 261-268
    • Smith, J.A.1    Wiedemann, M.J.2
  • 31
    • 1342324165 scopus 로고    scopus 로고
    • Labor induces a maternal inflammatory response syndrome
    • Molloy EJ, O'Neill AJ, Grantham JJ etal. Labor induces a maternal inflammatory response syndrome. Am J Obstet Gynecol 2004; 190:448-455.
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 448-455
    • Molloy, E.J.1    O'Neill, A.J.2    Grantham, J.J.3
  • 32
    • 37849015129 scopus 로고    scopus 로고
    • Maternal and neonatal lipopolysaccharide and Fas responses are altered by antenatal risk factors for sepsis
    • Molloy EJ, O'Neill AJ, Grantham-Sloan JJ, Webb DW, Watson RW. Maternal and neonatal lipopolysaccharide and Fas responses are altered by antenatal risk factors for sepsis. Clin Exp Immunol 2008; 151:244-250.
    • (2008) Clin Exp Immunol , vol.151 , pp. 244-250
    • Molloy, E.J.1    O'Neill, A.J.2    Grantham-Sloan, J.J.3    Webb, D.W.4    Watson, R.W.5
  • 33
    • 35448984512 scopus 로고    scopus 로고
    • Neonatal encephalopathy is associated with altered perinatal systemic neutrophil apoptosis
    • Molloy EJ, O'Neill AJ, Grantham-Sloan JJ etal. Neonatal encephalopathy is associated with altered perinatal systemic neutrophil apoptosis. Am J Perinatol 2007; 24:525-530.
    • (2007) Am J Perinatol , vol.24 , pp. 525-530
    • Molloy, E.J.1    O'Neill, A.J.2    Grantham-Sloan, J.J.3
  • 34
    • 84860456584 scopus 로고    scopus 로고
    • Long lasting local and systemic inflammation after cerebral hypoxic ischemia in newborn mice
    • Winerdal M, Winerdal ME, Kinn J, Urmaliya V, Winqvist O, Ådén U. Long lasting local and systemic inflammation after cerebral hypoxic ischemia in newborn mice. PLOS ONE 2012; 7:e36422.
    • (2012) PLOS ONE , vol.7 , pp. e36422
    • Winerdal, M.1    Winerdal, M.E.2    Kinn, J.3    Urmaliya, V.4    Winqvist, O.5    Ådén, U.6
  • 35
    • 79952582656 scopus 로고    scopus 로고
    • Systemic neutrophil activation in a mouse model of ischemic stroke and reperfusion
    • Morrison H, McKee D, Ritter L. Systemic neutrophil activation in a mouse model of ischemic stroke and reperfusion. Biol Res Nurs 2011; 13:154-163.
    • (2011) Biol Res Nurs , vol.13 , pp. 154-163
    • Morrison, H.1    McKee, D.2    Ritter, L.3
  • 36
    • 0036548360 scopus 로고    scopus 로고
    • The Toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS
    • Lehnard S, Lachance C, Patrizi S etal. The Toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS. J Neurosci 2002; 22:2478-2486.
    • (2002) J Neurosci , vol.22 , pp. 2478-2486
    • Lehnard, S.1    Lachance, C.2    Patrizi, S.3
  • 37
    • 35348860696 scopus 로고    scopus 로고
    • Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
    • Tang SC, Arumugam TV, Xu X, Cheng A, Mughal MR, Jo DG. Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci USA 2007; 104:13798-13803.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13798-13803
    • Tang, S.C.1    Arumugam, T.V.2    Xu, X.3    Cheng, A.4    Mughal, M.R.5    Jo, D.G.6
  • 38
    • 84884502306 scopus 로고    scopus 로고
    • Toll-like receptor 4 antagonist attenuates intracerebral hemorrhage-induced brain injury
    • Wang YC, Wang PF, Fang H, Chen J, Xiong XY, Yang QW. Toll-like receptor 4 antagonist attenuates intracerebral hemorrhage-induced brain injury. Stroke 2013; 44:2545-2552.
    • (2013) Stroke , vol.44 , pp. 2545-2552
    • Wang, Y.C.1    Wang, P.F.2    Fang, H.3    Chen, J.4    Xiong, X.Y.5    Yang, Q.W.6
  • 39
    • 3042685374 scopus 로고    scopus 로고
    • Labor promotes neonatal neutrophil survival and lipopolysaccharide responsiveness
    • Molloy EJ, O'Neill AJ, Grantham JJ etal. Labor promotes neonatal neutrophil survival and lipopolysaccharide responsiveness. Pediatr Res 2004; 56:99-103.
    • (2004) Pediatr Res , vol.56 , pp. 99-103
    • Molloy, E.J.1    O'Neill, A.J.2    Grantham, J.J.3
  • 42
    • 36349014743 scopus 로고    scopus 로고
    • Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions
    • Mosnier LO, Yanq XV, Griffin JH. Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions. J Biol Chem 2007; 282:33022-33033.
    • (2007) J Biol Chem , vol.282 , pp. 33022-33033
    • Mosnier, L.O.1    Yanq, X.V.2    Griffin, J.H.3
  • 43
    • 34948866150 scopus 로고    scopus 로고
    • Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
    • Kerschen EJ, Fernandez JA, Cooley BC etal. Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. J Exp Med 2007; 204:2439-2448.
    • (2007) J Exp Med , vol.204 , pp. 2439-2448
    • Kerschen, E.J.1    Fernandez, J.A.2    Cooley, B.C.3
  • 44
    • 79953161072 scopus 로고    scopus 로고
    • Cytoprotective protein C pathways and implications for stroke and neurological disorders
    • Zlokovic BV, Griffin JH. Cytoprotective protein C pathways and implications for stroke and neurological disorders. Trends Neurosci 2011; 34:198-209.
    • (2011) Trends Neurosci , vol.34 , pp. 198-209
    • Zlokovic, B.V.1    Griffin, J.H.2


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