Leukocyte count predicts outcome after ischemic stroke: The Northern Manhattan Stroke Study

Journal of Stroke and Cerebrovascular Diseases

Volumn 13, Issue 5, 2004, Pages 220-227

  Elkind, Mitchell S V ^a,b,d   Cheng, Jianfeng ^c   Rundek, Tanja ^a   Boden Albala, Bernadette ^b,c   Sacco, Ralph L ^a,b,c  

^a Columbia Univ Columbia Univ M ^*  (United States)

^b Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^c New York NY 10032 ^*  (United States)

^d NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Cerebral infarction; leukocytes; mortality; prognosis; stroke

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CAUCASIAN; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HEART INFARCTION; HISPANIC; HUMAN; LEUKOCYTE COUNT; MALE; NEGRO; OUTCOMES RESEARCH; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RACE DIFFERENCE; RISK FACTOR; SEX DIFFERENCE; STATISTICAL ANALYSIS; STROKE;

EID: 7044223228     PISSN: 10523057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2004.07.004     Document Type: Article

References (55)

1. G.D. Friedman, A.L. Klatsky, A.B. Siegelaub The leukocyte count as a predictor of myocardial infarction N Eng J Med 290 1974 1275 1278
2. J.B. Zalokar, J.L. Richard, J.R. Claude Leukocyte count, smoking, and myocardial infarction N Engl J Med 304 1981 465 468
3. R.L. Prentice, T.P. Szatrowski, T. Fujikura Leukocyte counts and coronary heart disease in a Japanese cohort Am J Epidemiol 116 1982 496 509
4. R.H. Grimm, J.D. Neaton, W. Ludwig Prognostic importance of the white blood cell count for coronary, cancer, and all-cause mortality JAMA 254 1985 1932 1937
5. J.W.G. Yarnell, I.A. Baker, P.M. Sweetnam Fibrinogen, viscosity, and white blood cell count are major risk factors for ischemic heart disease Circulation 83 1991 836 844
6. W.B. Kannel, K. Anderson, P.W. Wilson White blood cell count and cardiovascular disease. Insights from the Framingham Study JAMA 267 1992 1253 1256
7. P.M. Ridker, N. Rifai, M.J. Stampfer Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men Circulation 101 2000 1767 1772
8. P.M. Ridker, J.E. Buring, J. Shih Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women Circulation 98 1998 731 733
9. P.M. Ridker, M. Cushman, M.J. Stampfer Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men New Engl J Med 336 1997 973 979
10. P.M. Ridker, C.H. Hennekens, J.E. Buring C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women N Engl J Med 342 2000 836 843
11. P.M. Ridker, C.H. Hennekens, B. Roitman-Johnson Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men Lancet 351 1998 88 92
12. S.-J. Hwang, C.M. Ballantyne, A.R. Sharrett The Atherosclerosis Risk in Communities (ARIC) study Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases Circulation 96 1997 4219 4225
13. L.N. Biasucci, A. Vitelli, G. Liuzzo Elevated levels of interleukin-6 in unstable angina Circulation 94 1996 874 877
14. L.M. Biasucci, G. Liuzzo, R.L. Grillo Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability Circulation 99 1999 855 860
15. L.N. Biasucci, G. Liuzzo, G. Fantuzzi Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events Circulation 99 1999 2079 2084
16. T. Kanda, Y. Hirao, S. Oshima Interleukin-8 as a sensitive marker of unstable coronary artery disease Am J Cardiol 77 1996 304 307
17. P.M. Ridker, N. Rifai, M. Pfeffer Elevation of tumor necrosis factor-alpha and increased risk of recurrent coronary events after myocardial infarction Circulation 101 2000 2149 2153
18. R. Ross Atherosclerosis An inflammatory disease N Engl J Med 340 1999 115 126
19. A.J. Grau, F. Buggle, H. Becher The association of leukocyte count, fibrinogen and C-reactive protein with vascular risk factors and ischemic vascular diseases Thromb Res 82 1996 245 255
20. R.L. Prentice, T.P. Szatrowski, H. Kato Leukocyte counts and cerebrovascular disease J Chron Dis 35 1982 703 714
21. D. Noto, C.M. Barbagallo, G. Cavera Leukocyte count, diabetes mellitus and age are strong predictors of stroke in a rural population in southern Italy An 8-year follow-up Atherosclerosis 157 2001 225 231
22. A.J. Grau, A.W. Boddy, D.A. Dukovic Leukocyte count as an independent predictor of recurrent ischemic events Stroke 35 2004 1147 1152
23. R.J. Davenport, M.S. Dennis, I. Wellwood Complications after acute stroke Stroke 27 1996 415 420
24. M.S. Elkind, J. Cheng, B. Boden-Albala The Northern Manhattan Stroke Study Elevated white blood cell count and carotid plaque thickness Stroke 32 2001 842 849
25. M.S. Elkind, J. Cheng, B. Boden-Albala Tumor necrosis factor receptor levels are associated with carotid atherosclerosis Stroke 33 2002 31 38
26. R. Salonen, J.T. Salonen Progression of carotid atherosclerosis and its determinants A population-based ultrasonography study Atherosclerosis 81 1990 33 40
27. United States Census of Population and Housing, 1990 (public use microdata sample); available at www.census.gov.
28. R. Garfield D. Abramson Washington Heights/Inwood: The Health of a Community. The Health of the Public Program 1995 Columbia University Press New York
29. R.L. Sacco, R. Gan, B. Boden-Albala The Northern Manhattan Stroke Study Leisure-time physical activity and ischemic stroke risk Stroke 29 1998 380 387
30. R.L. Sacco, M.S. Elkind, B. Boden-Albala The protective effect of moderate alcohol consumption on ischemic stroke JAMA 281 1999 53 60
31. Office of Management and Budget Race and ethnic standards for federal statistics and administrative reporting (Directive no. 15) Fed Reg 43 1978 19269
32. E.M. Gentry, W.D. Kalsbeek, G. Hegelin The Behavioral Risk Factor Surveys: II. Design, methods, and estimates from combined state data Am J Prev Med 1 1985 9 14
33. R.L. Sacco, B. Boden-Albala, X. Chen Relationship of 6-month functional outcome and stroke severity Implications for acute stroke trials from the Northern Manhattan Stroke Study Neurology 50 suppl 4 1998 A327
34. R.L. Sacco, J.T. DeRosa, E.C. Haley Glycine antagonist in neuroprotection for patients with acute stroke JAMA 285 2001 1719 1728
35. H.P. Adams Jr, R.F. Woolson, W. Clarke Design of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) Control Clin Trials 18 1997 358 377
36. M.S. Elkind, I.-F. Lin, T.J. Grayston The Northern Manhattan Stroke Study Chlamydia pneumoniae and the risk of first ischemic stroke Stroke 31 2000 1521 1525
37. R.L. Sacco, B. Boden-Albala, R. Gan The Northern Manhattan Stroke Study Stroke incidence among white, black, and Hispanic residents of an urban community Am J Epidemiol 147 1998 259 268
38. G. Azzimondi, L. Bassein, F. Nonino Fever in acute stroke worsens prognosis A prospective study Stroke 26 1995 2040 2043
39. H.P. Adams Jr, P.H. Davis, E.C. Leira Baseline NIH Stroke Scale score strongly predicts outcome after stroke A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) Neurology 53 1999 126 131
40. S. Thompson, J. Kienast, S. Pyke Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris N Engl J Med 332 1995 635 641
41. G. Gheno, M. Libardoni, R. Zeppellini C-reactive protein on admission as a predictor of in-hospital death in the elderly with acute myocardial infarction Cardiologia 44 1999 1023 1028
42. J.B. Muhlestein, B.D. Horne, J.F. Carlquist Cytomegalovirus seropositivity and C-reactive protein have independent and combined predictive value for mortality in patients with angiographically demonstrated coronary artery disease Circulation 102 2000 1917 1923
43. N. Vila, J. Castillo, A. Davalos Proinflammatory cytokines and early neurological worsening in ischemic stroke Stroke 31 2000 2325 2329
44. N.B. Beamer, B.M. Coull, W.M. Clark Interleukin-6 and interleukin-1 receptor antagonist in acute stroke Ann Neurol 37 1995 800 805
45. K.W. Muir, C.J. Weir, W. Alwan C-reactive protein and outcome after ischemic stroke Stroke 30 1999 981 985
46. J.F. Arenillas, J. Alvarez-Sabin, C.A. Molina C-reactive protein predicts further ischemic events in first-ever transient ischemic attack or stroke patients with intracranial large-artery occlusive disease Stroke 34 2003 2463 2470
47. M. Di Napoli, F. Papa, V. Bocola Prognostic influence of increased C-reactive protein and fibrinogen levels in ischemic stroke Stroke 32 2001 133 138
48. K. Winbeck, H. Poppert, T. Etgen Prognostic relevance of early serial C-reactive protein measurements after first ischemic stroke Stroke 33 2002 2459 2464
49. G. Liuzzo, S.L. Kopecky, R.L. Frye Perturbation of the T-cell repertoire in patients with unstable angina Circulation 100 1999 2135 2139
50. S. Gupta, E.W. Leatham, D. Carrington Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction Circulation 96 1997 404 407
51. E. Gurfinkel, G. Bozovich, A. Daroca Randomised trial of roxithromycin in non-Q-wave coronary syndromes ROXIS pilot study Lancet 350 1997 404 407
52. E. Gurfinkel, G. Bozovich, E. Beck Treatment with the antibiotic roxithromycin in patients with acute non-Q-wave coronary syndromes. The final report of the ROXIS Study Eur Heart J 20 1999 121 127
53. J.B. Muhlestein, J.L. Anderson, E.H. Hammond Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model Circulation 97 1998 633 636
54. P.M. Ridker, N. Rifai, S.P. Lowenthal Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia Circulation 103 2001 1191 1193
55. M.A. Albert, E. Danielson, N. Rifai PRINCE investigators Effect of statin therapy on C-reactive protein levels. The pravastatin inflammation/CRP evaluation (PRINCE): A randomized trial and cohort study JAMA 286 2001 64 70