EGFR mediates astragaloside IV-induced Nrf2 activation to protect cortical neurons against in vitro ischemia/reperfusion damages

Biochemical and Biophysical Research Communications

Volumn 457, Issue 3, 2015, Pages 391-397

  Gu, Da Min ^a   Lu, Pei Hua ^b   Zhang, Ke ^a   Wang, Xiang ^a   Sun, Min ^a   Chen, Guo Qian ^b   Wang, Qiong ^b  

^a YIXING PEOPLE S HOSPITAL   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Astragaloside IV; EGFR; Ischemia reperfusion; Neuroprotection; Nrf2

Indexed keywords

ASTRAGALOSIDE IV; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCOSE; HEME OXYGENASE 1; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; OXYGEN; PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SHORT HAIRPIN RNA; SULPHIREDOXIN 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; ASTRAGALOSIDE A; HERBACEOUS AGENT; MESSENGER RNA; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE; SAPONIN; TRITERPENE;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN CELL; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; EMBRYO; GENE SILENCING; GENETIC TRANSCRIPTION; IN VITRO STUDY; LENTIVIRINAE; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CORTEX; DISEASE MODEL; DRUG EFFECTS; GENETICS; INJURIES; METABOLISM; PRIMARY CELL CULTURE; TRANSCRIPTION INITIATION;

MURINAE;

ANIMALS; ANTIOXIDANTS; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; GENE KNOCKDOWN TECHNIQUES; MICE; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPERFUSION INJURY; RNA, MESSENGER; SAPONINS; TRANSCRIPTIONAL ACTIVATION; TRITERPENES;

EID: 84922718311     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.01.002     Document Type: Article

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