Getting nervous about immunity

Seminars in Immunology

Volumn 26, Issue 5, 2014, Pages 389-393

  Kelley, Keith W ^a   McCusker, Robert H ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Behavior; Immunophysiology; Inflammation; Neuroimmunology; Psychoneuroimmunology; Symptoms

Indexed keywords

ACETYLCHOLINE; CYTOKINE; GLUCOCORTICOID; INTERLEUKIN 1; NEUROPEPTIDE; NEUROTRANSMITTER; TUMOR NECROSIS FACTOR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS;

BLOOD BRAIN BARRIER; HUMAN; IMMUNITY; IMMUNOLOGY; LYMPHOID CELL; MACROPHAGE ACTIVATION; NEUROIMMUNOLOGY; NEUROSCIENCE; NONHUMAN; REVIEW; STRESS; ADRENAL GLAND; ANIMAL; HYPOTHALAMUS; IMMUNE SYSTEM; LYMPHOCYTE; METABOLISM; NERVE CELL; NEUROSECRETION; SIGNAL TRANSDUCTION;

ACETYLCHOLINE; ADRENAL GLANDS; ANIMALS; CYTOKINES; GLUCOCORTICOIDS; HUMANS; HYPOTHALAMUS; IMMUNE SYSTEM; LYMPHOCYTES; NEURONS; NEUROSECRETORY SYSTEMS; NEUROTRANSMITTER AGENTS; SIGNAL TRANSDUCTION;

EID: 84922716995     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2014.01.011     Document Type: Review

References (27)

1. Ader R., Cohen N., Felten D.L. Brain, behavior, and immunity. Brain Behav Immun 1987, 1:1-6.
2. Kelley K.W., Johnson R.W., Dantzer R. Immunology discovers physiology. Vet Immunol Immunopathol 1994, 43:157-165.
3. Raison C.L., Miller A.H. Malaise, melancholia and madness: the evolutionary legacy of an inflammatory bias. Brain Behav Immun 2013, 31:1-8.
4. Olofsson P.S., Rosas-Ballina M., Levine Y.A., Tracey K.J. Rethinking inflammation: neural circuits in the regulation of immunity. Immunol Rev 2012, 248:188-204.
5. Dantzer R., Kelley K.W. Twenty years of research on cytokine-induced sickness behavior. Brain Behav Immun 2007, 21:153-160.
6. Kelley K.W., Bluthe R.M., Dantzer R., Zhou J.H., Shen W.H., Johnson R.W., et al. Cytokine-induced sickness behavior. Brain Behav Immun 2003, 17(Suppl 1):S112-S118.
7. Jurgens H.A., Amancherla K., Johnson R.W. Influenza infection induces neuroinflammation, alters hippocampal neuron morphology, and impairs cognition in adult mice. J Neurosci 2012, 32:3958-3968.
8. McCusker R.H., Kelley K.W. Immune-neural connections: how the immune system's response to infectious agents influences behavior. J Expt Biol 2013, 21:684-698.
9. D'Mello C., Swain M.G. Liver-brain interactions in inflammatory liver diseases: implications for fatigue and mood disorders. Brain Behav Immun 2013.
10. Lampron A., Elali A., Rivest S. Innate immunity in the CNS: redefining the relationship between the CNS and its environment. Neuron 2013, 78:214-232.
11. Carare R.O., Hawkes C.A., Weller R.O. Afferent and efferent immunological pathways of the brain. Anatomy, Function and Failure. Brain Behav Immun 2014, 36:9-14.
12. Quan N., Banks W.A. Brain-immune communication pathways. Brain Behav Immun 2007, 21:727-735.
13. Wan W., Wetmore L., Sorensen C.M., Greenberg A.H., Nance D.M. Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain. Brain Res Bull 1994, 34:7-14.
14. Goehler L.E., Gaykema R.P., Hansen M.K., Anderson K., Maier S.F., Watkins L.R. Vagal immune-to-brain communication: a visceral chemosensory pathway. Auton Neurosci 2000, 85:49-59.
15. Marvel F.A., Chen C.C., Badr N., Gaykema R.P., Goehler L.E. Reversible inactivation of the dorsal vagal complex blocks lipopolysaccharide-induced social withdrawal and c-Fos expression in central autonomic nuclei. Brain Behav Immun 2004, 18:123-134.
16. Takeshita Y., Ransohoff R.M. Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models. Immunol Rev 2012, 248:228-239.
17. Komal P., Gudavicius G., Nelson C.J., Nashmi R. T-cell receptor activation decreases excitability of cortical interneurons by inhibiting alpha7 nicotinic receptors. J Neurosci 2014, 34:22-35.
18. Berkenbosch F., van Oers J., del Rey A., Tilders F., Besedovsky H. Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1. Science 1987, 238:524-526.
19. Sapolsky R., Rivier C., Yamamoto G., Plotsky P., Vale W. Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor. Science 1987, 238:522-524.
20. Morrissey P.J., Charrier K., Alpert A., Bressler L. In vivo administration of IL-1 induces thymic hypoplasia and increased levels of serum corticosterone. J Immunol 1988, 141:1456-1463.
21. Walker F.R., Nilsson M., Jones K. Acute and chronic stress-induced disturbances of microglial plasticity, phenotype and function. Curr Drug Targets 2013, 14:1262-1276.
22. Tynan R.J., Naicker S., Hinwood M., Nalivaiko E., Buller K.M., Pow D.V., et al. Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions. Brain Behav Immun 2010, 24:1058-1068.
23. Borovikova L.V., Ivanova S., Zhang M., Yang H., Botchkina G.I., Watkins L.R., et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 2000, 405:458-462.
24. Ji H., Rabbi M.F., Labis B., Pavlov V.A., Tracey K.J., Ghia J.E. Central cholinergic activation of a vagus nerve-to-spleen circuit alleviates experimental colitis. Mucosal Immunol 2013.
25. Reardon C., Duncan G.S., Brustle A., Brenner D., Tusche M.W., Olofsson P.S., et al. Lymphocyte-derived ACh regulates local innate but not adaptive immunity. Proc Natl Acad Sci U S A 2013, 110:1410-1415.
26. Pavlov V.A., Tracey K.J. The vagus nerve and the inflammatory reflex-linking immunity and metabolism. Nat Rev Endocrinol 2012, 8:743-754.
27. Andersson U., Tracey K.J. A new approach to rheumatoid arthritis: treating inflammation with computerized nerve stimulation. Cerebrum 2012, 2012:3.