-
1
-
-
34249026483
-
Live attenuated Salmonella as a vector for oral cytokine gene therapy in melanoma
-
Agorio, C., Schreiber, F., Sheppard, M., Mastroeni, P., Fernandez, M., Martinez, M.A., and Chabalgoity, J.A. (2007) Live attenuated Salmonella as a vector for oral cytokine gene therapy in melanoma. J Gene Med 9: 416-423.
-
(2007)
J Gene Med
, vol.9
, pp. 416-423
-
-
Agorio, C.1
Schreiber, F.2
Sheppard, M.3
Mastroeni, P.4
Fernandez, M.5
Martinez, M.A.6
Chabalgoity, J.A.7
-
2
-
-
20544437792
-
Attenuated Salmonella typhimurium invades and decreases tumor burden in neuroblastoma
-
discussion 997-998.
-
Barnett, S.J., Soto, L.J., 3rd, Sorenson, B.S., Nelson, B.W., Leonard, A.S., and Saltzman, D.A. (2005) Attenuated Salmonella typhimurium invades and decreases tumor burden in neuroblastoma. J Pediatr Surg 40: 993-997, discussion 997-998.
-
(2005)
J Pediatr Surg
, vol.40
, pp. 993-997
-
-
Barnett, S.J.1
Soto, L.J.2
Sorenson, B.S.3
Nelson, B.W.4
Leonard, A.S.5
Saltzman, D.A.6
-
3
-
-
14244259796
-
Suicide gene therapy with an adenovirus expressing the fusion gene CD: UPRT in human glioblastomas: different sensitivities correlate with p53 status
-
Bourbeau, D., Lavoie, G., Nalbantoglu, J., and Massie, B. (2004) Suicide gene therapy with an adenovirus expressing the fusion gene CD: UPRT in human glioblastomas: different sensitivities correlate with p53 status. J Gene Med 6: 1320-1332.
-
(2004)
J Gene Med
, vol.6
, pp. 1320-1332
-
-
Bourbeau, D.1
Lavoie, G.2
Nalbantoglu, J.3
Massie, B.4
-
4
-
-
79955046293
-
Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium
-
Crull, K., Bumann, D., and Weiss, S. (2011) Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium. FEMS Immunol Med Microbiol 62: 75-83.
-
(2011)
FEMS Immunol Med Microbiol
, vol.62
, pp. 75-83
-
-
Crull, K.1
Bumann, D.2
Weiss, S.3
-
5
-
-
0024315974
-
Enhancement of 5-fluorouracil antitumor effects by the prior administration of methotrexate
-
Damon, L.E., Cadman, E., and Benz, C. (1989) Enhancement of 5-fluorouracil antitumor effects by the prior administration of methotrexate. Pharmacol Ther 43: 155-185.
-
(1989)
Pharmacol Ther
, vol.43
, pp. 155-185
-
-
Damon, L.E.1
Cadman, E.2
Benz, C.3
-
6
-
-
0034612342
-
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
-
Datsenko, K.A., and Wanner, B.L. (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97: 6640-6645.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6640-6645
-
-
Datsenko, K.A.1
Wanner, B.L.2
-
7
-
-
33746620404
-
Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery
-
De Angelis, P.M., Svendsrud, D.H., Kravik, K.L., and Stokke, T. (2006) Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. Mol Cancer 5: 20.
-
(2006)
Mol Cancer
, vol.5
, pp. 20
-
-
De Angelis, P.M.1
Svendsrud, D.H.2
Kravik, K.L.3
Stokke, T.4
-
8
-
-
0034660858
-
In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene
-
Erbs, P., Regulier, E., Kintz, J., Leroy, P., Poitevin, Y., Exinger, F., etal. (2000) In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene. Cancer Res 60: 3813-3822.
-
(2000)
Cancer Res
, vol.60
, pp. 3813-3822
-
-
Erbs, P.1
Regulier, E.2
Kintz, J.3
Leroy, P.4
Poitevin, Y.5
Exinger, F.6
-
9
-
-
77958488277
-
Engineering the perfect (bacterial) cancer therapy
-
Forbes, N.S. (2010) Engineering the perfect (bacterial) cancer therapy. Nat Rev Cancer 10: 785-794.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 785-794
-
-
Forbes, N.S.1
-
10
-
-
25844433671
-
5-fluorouracil forward mutation assay in Salmonella: determination of mutational target and spontaneous mutational spectra
-
Glaab, W.E., Mitchell, L.S., Miller, J.E., Vlasakova, K., and Skopek, T.R. (2005) 5-fluorouracil forward mutation assay in Salmonella: determination of mutational target and spontaneous mutational spectra. Mutat Res 578: 238-246.
-
(2005)
Mutat Res
, vol.578
, pp. 238-246
-
-
Glaab, W.E.1
Mitchell, L.S.2
Miller, J.E.3
Vlasakova, K.4
Skopek, T.R.5
-
11
-
-
0022649516
-
Conversion of 5-fluorocytosine to 5-fluorouracil by human intestinal microflora
-
Harris, B.E., Manning, B.W., Federle, T.W., and Diasio, R.B. (1986) Conversion of 5-fluorocytosine to 5-fluorouracil by human intestinal microflora. Antimicrob Agents Chemother 29: 44-48.
-
(1986)
Antimicrob Agents Chemother
, vol.29
, pp. 44-48
-
-
Harris, B.E.1
Manning, B.W.2
Federle, T.W.3
Diasio, R.B.4
-
12
-
-
84897440929
-
Anti-tumoral effect of the mitochondrial target domain of Noxa delivered by an engineered Salmonella typhimurium
-
Jeong, J.H., Kim, K., Lim, D., Jeong, K., Hong, Y., Nguyen, V.H., etal. (2014) Anti-tumoral effect of the mitochondrial target domain of Noxa delivered by an engineered Salmonella typhimurium. PLoS ONE 9: e80050.
-
(2014)
PLoS ONE
, vol.9
, pp. e80050
-
-
Jeong, J.H.1
Kim, K.2
Lim, D.3
Jeong, K.4
Hong, Y.5
Nguyen, V.H.6
-
13
-
-
0010109877
-
Apoptosis of human intestinal epithelial cells after bacterial invasion
-
Kim, J.M., Eckmann, L., Savidge, T.C., Lowe, D.C., Witthoft, T., and Kagnoff, M.F. (1998) Apoptosis of human intestinal epithelial cells after bacterial invasion. J Clin Invest 102: 1815-1823.
-
(1998)
J Clin Invest
, vol.102
, pp. 1815-1823
-
-
Kim, J.M.1
Eckmann, L.2
Savidge, T.C.3
Lowe, D.C.4
Witthoft, T.5
Kagnoff, M.F.6
-
14
-
-
0036019203
-
Tumor-targeted Salmonella expressing cytosine deaminase as an anticancer agent
-
King, I., Bermudes, D., Lin, S., Belcourt, M., Pike, J., Troy, K., etal. (2002) Tumor-targeted Salmonella expressing cytosine deaminase as an anticancer agent. Hum Gene Ther 13: 1225-1233.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1225-1233
-
-
King, I.1
Bermudes, D.2
Lin, S.3
Belcourt, M.4
Pike, J.5
Troy, K.6
-
15
-
-
0013895829
-
The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man
-
Koechlin, B.A., Rubio, F., Palmer, S., Gabriel, T., and Duschinsky, R. (1966) The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man. Biochem Pharmacol 15: 435-446.
-
(1966)
Biochem Pharmacol
, vol.15
, pp. 435-446
-
-
Koechlin, B.A.1
Rubio, F.2
Palmer, S.3
Gabriel, T.4
Duschinsky, R.5
-
16
-
-
0031788385
-
Bystander effect caused by cytosine deaminase gene and 5-fluorocytosine in vitro is substantially mediated by generated 5-fluorouracil
-
Kuriyama, S., Masui, K., Sakamoto, T., Nakatani, T., Kikukawa, M., Tsujinoue, H., etal. (1998) Bystander effect caused by cytosine deaminase gene and 5-fluorocytosine in vitro is substantially mediated by generated 5-fluorouracil. Anticancer Res 18: 3399-3406.
-
(1998)
Anticancer Res
, vol.18
, pp. 3399-3406
-
-
Kuriyama, S.1
Masui, K.2
Sakamoto, T.3
Nakatani, T.4
Kikukawa, M.5
Tsujinoue, H.6
-
17
-
-
0032526178
-
Preferential cytotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-flucytosine
-
Lawrence, T.S., Rehemtulla, A., Ng, E.Y., Wilson, M., Trosko, J.E., and Stetson, P.L. (1998) Preferential cytotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-flucytosine. Cancer Res 58: 2588-2593.
-
(1998)
Cancer Res
, vol.58
, pp. 2588-2593
-
-
Lawrence, T.S.1
Rehemtulla, A.2
Ng, E.Y.3
Wilson, M.4
Trosko, J.E.5
Stetson, P.L.6
-
18
-
-
77956484714
-
Salmonella-allies in the fight against cancer
-
Leschner, S., and Weiss, S. (2010) Salmonella-allies in the fight against cancer. J Mol Med (Berl) 88: 763-773.
-
(2010)
J Mol Med (Berl)
, vol.88
, pp. 763-773
-
-
Leschner, S.1
Weiss, S.2
-
19
-
-
0026345034
-
Intracellular replication is essential for the virulence of Salmonella typhimurium
-
Leung, K.Y., and Finlay, B.B. (1991) Intracellular replication is essential for the virulence of Salmonella typhimurium. Proc Natl Acad Sci USA 88: 11470-11474.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11470-11474
-
-
Leung, K.Y.1
Finlay, B.B.2
-
20
-
-
34248660255
-
Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of L-arabinose as inducer of bacterial gene expression in vivo
-
Loessner, H., Endmann, A., Leschner, S., Westphal, K., Rohde, M., Miloud, T., etal. (2007) Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of L-arabinose as inducer of bacterial gene expression in vivo. Cell Microbiol 9: 1529-1537.
-
(2007)
Cell Microbiol
, vol.9
, pp. 1529-1537
-
-
Loessner, H.1
Endmann, A.2
Leschner, S.3
Westphal, K.4
Rohde, M.5
Miloud, T.6
-
21
-
-
0033574207
-
Kinetic mechanism of uracil phosphoribosyltransferase from Escherichia coli and catalytic importance of the conserved proline in the PRPP binding site
-
Lundegaard, C., and Jensen, K.F. (1999) Kinetic mechanism of uracil phosphoribosyltransferase from Escherichia coli and catalytic importance of the conserved proline in the PRPP binding site. Biochemistry 38: 3327-3334.
-
(1999)
Biochemistry
, vol.38
, pp. 3327-3334
-
-
Lundegaard, C.1
Jensen, K.F.2
-
22
-
-
79960951664
-
Improved expression systems for regulated expression in Salmonella infecting eukaryotic cells
-
Medina, C., Camacho, E.M., Flores, A., Mesa-Pereira, B., and Santero, E. (2011) Improved expression systems for regulated expression in Salmonella infecting eukaryotic cells. PLoS ONE 6: e23055.
-
(2011)
PLoS ONE
, vol.6
, pp. e23055
-
-
Medina, C.1
Camacho, E.M.2
Flores, A.3
Mesa-Pereira, B.4
Santero, E.5
-
23
-
-
84886934810
-
Novel tools to analyze the function of Salmonella effectors show that SvpB ectopic expression induces cell cycle arrest in tumor cells
-
Mesa-Pereira, B., Medina, C., Camacho, E.M., Flores, A., and Santero, E. (2013) Novel tools to analyze the function of Salmonella effectors show that SvpB ectopic expression induces cell cycle arrest in tumor cells. PLoS ONE 8: e78458.
-
(2013)
PLoS ONE
, vol.8
, pp. e78458
-
-
Mesa-Pereira, B.1
Medina, C.2
Camacho, E.M.3
Flores, A.4
Santero, E.5
-
24
-
-
0642374238
-
A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage
-
Meyers, M., Hwang, A., Wagner, M.W., Bruening, A.J., Veigl, M.L., Sedwick, W.D., and Boothman, D.A. (2003) A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage. Oncogene 22: 7376-7388.
-
(2003)
Oncogene
, vol.22
, pp. 7376-7388
-
-
Meyers, M.1
Hwang, A.2
Wagner, M.W.3
Bruening, A.J.4
Veigl, M.L.5
Sedwick, W.D.6
Boothman, D.A.7
-
25
-
-
12444302834
-
Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients
-
Nemunaitis, J., Cunningham, C., Senzer, N., Kuhn, J., Cramm, J., Litz, C., etal. (2003) Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients. Cancer Gene Ther 10: 737-744.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 737-744
-
-
Nemunaitis, J.1
Cunningham, C.2
Senzer, N.3
Kuhn, J.4
Cramm, J.5
Litz, C.6
-
26
-
-
0021880212
-
Antineoplastic effects in rats of 5-fluorocytosine in combination with cytosine deaminase capsules
-
Nishiyama, T., Kawamura, Y., Kawamoto, K., Matsumura, H., Yamamoto, N., Ito, T., etal. (1985) Antineoplastic effects in rats of 5-fluorocytosine in combination with cytosine deaminase capsules. Cancer Res 45: 1753-1761.
-
(1985)
Cancer Res
, vol.45
, pp. 1753-1761
-
-
Nishiyama, T.1
Kawamura, Y.2
Kawamoto, K.3
Matsumura, H.4
Yamamoto, N.5
Ito, T.6
-
27
-
-
0036854564
-
Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells
-
Paesold, G., Guiney, D.G., Eckmann, L., and Kagnoff, M.F. (2002) Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells. Cell Microbiol 4: 771-781.
-
(2002)
Cell Microbiol
, vol.4
, pp. 771-781
-
-
Paesold, G.1
Guiney, D.G.2
Eckmann, L.3
Kagnoff, M.F.4
-
28
-
-
0030854392
-
Tumor-targeted Salmonella as a novel anticancer vector
-
Pawelek, J.M., Low, K.B., and Bermudes, D. (1997) Tumor-targeted Salmonella as a novel anticancer vector. Cancer Res 57: 4537-4544.
-
(1997)
Cancer Res
, vol.57
, pp. 4537-4544
-
-
Pawelek, J.M.1
Low, K.B.2
Bermudes, D.3
-
29
-
-
0028888329
-
Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil
-
Pizzorno, G., Sun, Z., and Handschumacher, R.E. (1995) Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil. Biochem Pharmacol 49: 553-557.
-
(1995)
Biochem Pharmacol
, vol.49
, pp. 553-557
-
-
Pizzorno, G.1
Sun, Z.2
Handschumacher, R.E.3
-
30
-
-
0016790323
-
Mode of action of 5-fluorocytosine and mechanisms of resistance
-
Polak, A., and Scholer, H.J. (1975) Mode of action of 5-fluorocytosine and mechanisms of resistance. Chemotherapy 21: 113-130.
-
(1975)
Chemotherapy
, vol.21
, pp. 113-130
-
-
Polak, A.1
Scholer, H.J.2
-
31
-
-
3242673522
-
Extracellular expression of cytosine deaminase results in increased 5-FU production for enhanced enzyme/prodrug therapy
-
Rehemtulla, A., Hamstra, D.A., Kievit, E., Davis, M.A., Ng, E.Y., Dornfeld, K., and Lawrence, T.S. (2004) Extracellular expression of cytosine deaminase results in increased 5-FU production for enhanced enzyme/prodrug therapy. Anticancer Res 24: 1393-1399.
-
(2004)
Anticancer Res
, vol.24
, pp. 1393-1399
-
-
Rehemtulla, A.1
Hamstra, D.A.2
Kievit, E.3
Davis, M.A.4
Ng, E.Y.5
Dornfeld, K.6
Lawrence, T.S.7
-
32
-
-
35748986144
-
In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit
-
Royo, J.L., Becker, P.D., Camacho, E.M., Cebolla, A., Link, C., Santero, E., and Guzman, C.A. (2007) In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit. Nat Methods 4: 937-942.
-
(2007)
Nat Methods
, vol.4
, pp. 937-942
-
-
Royo, J.L.1
Becker, P.D.2
Camacho, E.M.3
Cebolla, A.4
Link, C.5
Santero, E.6
Guzman, C.A.7
-
33
-
-
0029936191
-
Attenuated Salmonella typhimurium containing interleukin-2 decreases MC-38 hepatic metastases: a novel anti-tumor agent
-
Saltzman, D.A., Heise, C.P., Hasz, D.E., Zebede, M., Kelly, S.M., Curtiss, R., 3rd, etal. (1996) Attenuated Salmonella typhimurium containing interleukin-2 decreases MC-38 hepatic metastases: a novel anti-tumor agent. Cancer Biother Radiopharm 11: 145-153.
-
(1996)
Cancer Biother Radiopharm
, vol.11
, pp. 145-153
-
-
Saltzman, D.A.1
Heise, C.P.2
Hasz, D.E.3
Zebede, M.4
Kelly, S.M.5
Curtiss, R.6
-
34
-
-
0032810342
-
Effect of 5-fluorouracil on cell cycle regulatory proteins in human colon cancer cell line
-
Takeda, H., Haisa, M., Naomoto, Y., Kawashima, R., Satomoto, K., Yamatuji, T., and Tanaka, N. (1999) Effect of 5-fluorouracil on cell cycle regulatory proteins in human colon cancer cell line. Jpn J Cancer Res 90: 677-684.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 677-684
-
-
Takeda, H.1
Haisa, M.2
Naomoto, Y.3
Kawashima, R.4
Satomoto, K.5
Yamatuji, T.6
Tanaka, N.7
-
35
-
-
0033869563
-
Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions
-
Vermes, A., Guchelaar, H.J., and Dankert, J. (2000) Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions. J Antimicrob Chemother 46: 171-179.
-
(2000)
J Antimicrob Chemother
, vol.46
, pp. 171-179
-
-
Vermes, A.1
Guchelaar, H.J.2
Dankert, J.3
-
36
-
-
42349102915
-
Containment of tumor-colonizing bacteria by host neutrophils
-
Westphal, K., Leschner, S., Jablonska, J., Loessner, H., and Weiss, S. (2008) Containment of tumor-colonizing bacteria by host neutrophils. Cancer Res 68: 2952-2960.
-
(2008)
Cancer Res
, vol.68
, pp. 2952-2960
-
-
Westphal, K.1
Leschner, S.2
Jablonska, J.3
Loessner, H.4
Weiss, S.5
-
37
-
-
78449281712
-
Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer
-
Yam, C., Zhao, M., Hayashi, K., Ma, H., Kishimoto, H., McElroy, M., etal. (2010) Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer. J Surg Res 164: 248-255.
-
(2010)
J Surg Res
, vol.164
, pp. 248-255
-
-
Yam, C.1
Zhao, M.2
Hayashi, K.3
Ma, H.4
Kishimoto, H.5
McElroy, M.6
-
38
-
-
0035110959
-
Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy
-
Yoshikawa, R., Kusunoki, M., Yanagi, H., Noda, M., Furuyama, J.I., Yamamura, T., and Hashimoto-Tamaoki, T. (2001) Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy. Cancer Res 61: 1029-1037.
-
(2001)
Cancer Res
, vol.61
, pp. 1029-1037
-
-
Yoshikawa, R.1
Kusunoki, M.2
Yanagi, H.3
Noda, M.4
Furuyama, J.I.5
Yamamura, T.6
Hashimoto-Tamaoki, T.7
-
39
-
-
33747878325
-
Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice
-
Zhao, M., Yang, M., Ma, H., Li, X., Tan, X., Li, S., etal. (2006) Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice. Cancer Res 66: 7647-7652.
-
(2006)
Cancer Res
, vol.66
, pp. 7647-7652
-
-
Zhao, M.1
Yang, M.2
Ma, H.3
Li, X.4
Tan, X.5
Li, S.6
|