A simple approach for producing highly efficient DNA carriers with reduced toxicity based on modified polyallylamine

Materials Science and Engineering C

Volumn 49, Issue , 2015, Pages 290-296

  Oskuee, Reza Kazemi ^a,b   Dosti, Fatemeh ^b   Gholami, Leila ^c   Malaekeh Nikouei, Bizhan ^d  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acrylate; Cytotoxicity; Gene delivery; Non viral vectors; Polyallylamine; Transfection

Indexed keywords

CELL CULTURE; CYTOTOXICITY; DNA; EFFICIENCY; GENE TRANSFER; GENES; GRAFTING (CHEMICAL); MOLECULAR BIOLOGY; PARTICLE SIZE; POLYMERS; TOXICITY; ZETA POTENTIAL;

ACRYLATE; GENE DELIVERY; NONVIRAL VECTORS; POLYALLYLAMINE; TRANSFECTION;

VECTORS;

CATION; DNA; POLYALLYLAMINE; POLYAMINE; POLYETHYLENEIMINE; POLYMER;

ANIMAL; CELL SURVIVAL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; METABOLISM; MOLECULAR WEIGHT; MOUSE; PARTICLE SIZE; PROCEDURES; TUMOR CELL LINE;

ANIMALS; CATIONS; CELL LINE, TUMOR; CELL SURVIVAL; DNA; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICE; MOLECULAR WEIGHT; PARTICLE SIZE; POLYAMINES; POLYETHYLENEIMINE; POLYMERS; TRANSFECTION;

EID: 84922699121     PISSN: 09284931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.msec.2015.01.016     Document Type: Article

References (32)

1. N. Oku, Y. Yamazaki, M. Matsuura, M. Sugiyama, M. Hasegawa, and M. Nango A novel non-viral gene transfer system, polycation liposomes Adv. Drug Deliv. Rev. 52 2001 209 218
2. Y.S. Wong, M.J. Pelet, and D. Putnam Polymer systems for gene delivery - past, present, and future Prog. Polym. Sci. 32 2007 799 837
3. I.M. Verma, and N. Somia Gene therapy - promises, problems and prospects Nature 389 1997 239 242
4. M. Thomas, and A.M. Klibanov Non-viral gene therapy: polycation-mediated DNA delivery Appl. Microbiol. Biotechnol. 62 2003 27 34
5. A. El-Aneed An overview of current delivery systems in cancer gene therapy J. Control. Release 94 2004 1 14
6. J. Kunisawa, and T. Mayumi Application of novel drug delivery system, fusogenic liposome, for cancer therapy Gan To Kagaku Ryoho 28 2001 577 583
7. S.L. Hart Lipid carriers for gene therapy Curr. Drug Deliv. 2 2005 423 428
8. P.R. Cullis, and A. Chonn Recent advances in liposome technologies and their applications for systemic gene delivery Adv. Drug Deliv. Rev. 30 1998 73 83
9. P. Midoux, G. Breuzard, J.P. Gomez, and C. Pichon Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes Curr. Gene Ther. 8 2008 335 352
10. R.K. Oskuee, E. Mohtashami, L. Golami, and B. Malaekeh-Nikouei Cationic liposomes-polyallylamine-plasmid nanocomplexes for gene delivery J. Exp. Nanosci. 9 2014 1026 1034
11. M. Thomas, and A.M. Klibanov Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells Proc. Natl. Acad. Sci. U. S. A. 99 2002 14640 14645
12. A. Dehshahri, R.K. Oskuee, W. Thomas Shier, and M. Ramezani Targeted plasmid DNA delivery by galactosylated alkyl-oligoamine derivatives of PEI Eur. Cell Mater. 19 2010 8
13. A. Dehshahri, R.K. Oskuee, W. Thomas Shier, and M. Ramezani β-Galactosylated alkyl-oligoamine derivatives of polyethylenimine enhanced pDNA delivery into hepatic cells with reduced toxicity Curr. Nanosci. 8 2012 548 555
14. S. Nimesh, R. Kumar, and R. Chandra Novel polyallylamine-dextran sulfate-DNA nanoplexes: highly efficient non-viral vector for gene delivery Int. J. Pharm. 320 2006 143 149
15. A. Pathak, A. Aggarwal, R.K. Kurupati, S. Patnaik, A. Swami, Y. Singh, P. Kumar, S.P. Vyas, and K.C. Gupta Engineered polyallylamine nanoparticles for efficient in vitro transfection Pharm. Res. 24 2007 1427 1440
16. A. Zintchenko, A. Philipp, A. Dehshahri, and E. Wagner Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity Bioconjug. Chem. 19 2008 1448 1455
17. S.L. Snyder, and P.Z. Sobocinski An improved 2,4,6-trinitrobenzenesulfonic acid method for the determination of amines Anal. Biochem. 64 1975 284 288
18. M. Mahato, G. Rana, P. Kumar, and A.K. Sharma Tetramethylguanidinium-polyallylamine (Tmg-PA): A new class of nonviral vector for efficient gene transfection, J. Polym. Sci. 50 2012 2344 2355
19. C. Tros de Ilarduya, Y. Sun, and N. Duzgunes Gene delivery by lipoplexes and polyplexes Eur. J. Pharm. Sci. 40 2010 159 170
20. M. Neu, D. Fischer, and T. Kissel Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives J. Gene Med. 7 2005 992 1009
21. Z. Lin, C. Wang, X. Feng, M. Liu, J. Li, and C. Bai The observation of the local ordering characteristics of spermidine-condensed DNA: atomic force microscopy and polarizing microscopy studies Nucleic Acids Res. 26 1998 3228 3234
22. N.P. Gabrielson, and D.W. Pack Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions Biomacromolecules 7 2006 2427 2435
23. J. Rejman, V. Obevle, I.S. Zuhom, and D. Hockstar Size-dependent internalization of particle via the pathways of clothrin and caveoline-mediated endocytosis Biochem. J. 377 2004 159 169
24. I.A. Khalil, K. Kogure, H. Akita, and H. Harashima Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery Pharmacol. Rev. 58 2006 32 45
25. M.L. Forrest, G.E. Meister, J.T. Koerber, and D.W. Pack Partial acetylation of polyethylenimine enhances in vitro gene delivery Pharm. Res. 21 2004 365 371
26. Z. Sabahi, S.M. Samani, and A. Dehshahri Conjugation of poly(amidoamine) dendrimers with various acrylates for improved delivery of plasmid encoding interleukin-12 gene J. Biomater. Appl. Sep 10 2014 (pii: 0885328214551010. Epub ahead of print)
27. A. Dehshahri, R.K. Oskuee, W.T. Shier, A. Hatefi, and M. Ramezani Gene transfer efficiency of high primary amine content, hydrophobic, alkyl-oligoamine derivatives of polyethylenimine Biomaterials 30 2009 4187 4194
28. R.K. Oskuee, A. Dehshahri, W.T. Shier, and M. Ramezani Modified polyethyleneimine: self assemble nanoparticle forming polymer for pDNA delivery, Iran J. Basic Med. Sci. 11 2008 33 40
29. R.K. Oskuee, A. Dehshahri, W.T. Shier, and M. Ramezani Alkylcarboxylate grafting to polyethylenimine: a simple approach to producing a DNA nanocarrier with low toxicity J. Gene Med. 11 2009 921 932
30. D. Fischer, T. Bieber, Y. LI, H.P. Elsassar, and T. Kissel A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of Hmolecular weight on transfection efficiency and cytotoxicity Pharm. Res. 16 1999 1273 1279
31. L. Gholami, H.R. Sadeghnia, M. Darroudi, and R.K. Oskuee Evaluation of genotoxicity and cytotoxicity induced by different molecular weights of polyethylenimine/DNA nanoparticles Turk. J. Biol. 38 2014 380 387
32. K. Kunath, T. Merdan, O. Hegener, H. Haberlein, and T. Kissel Integrin targeting using RGD-PEI conjugates for in vitro gene transfer J. Gene Med. 5 2003 588 599