Effects of dietary supplementation of a zinc oxide product encapsulated with lipid on growth performance, intestinal morphology, and digestive enzyme activities in weanling pigs

Animal Feed Science and Technology

Volumn 200, Issue 1, 2015, Pages 112-117

  Park, B C ^a   Jung, D Y ^b   Kang, S Y ^b   Ko, Y H ^b   Ha, D M ^b   Kwon, C H ^c   Park, M J ^b   Han, J H ^c   Jang, I ^b   Lee, C Y ^b  

^a R and D Institute Sunjin Co Ltd   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

Diarrhea; Digestive enzyme; Growth performance; Villus morphology; Weanling pig; Zinc oxide

Indexed keywords

ANIMALIA; SUIDAE;

EID: 84922652313     PISSN: 03778401     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anifeedsci.2014.11.016     Document Type: Article

References (22)

1. Carlson D., Poulsen H.D., Vestergaard M. Additional dietary zinc for weaning piglets is associated with elevated concentrations of serum IGF-I. J. Anim. Physiol. Anim. Nutr. 2004, 88:332-339.
2. Dintzis F.R., Laszlo J.A., Nelsen T.C., Baker F.L., Calvert C.C. Free and total ion concentrations in pig digesta. J. Anim. Sci. 1995, 73:1138-1146.
3. Hahn J.D., Baker D.H. Growth and plasma zinc responses of young pigs fed pharmacologic levels of zinc. J. Anim. Sci. 1993, 71:3020-3024.
4. Hedemann M.S., Jensen B.B., Poulsen H.D. Influence of dietary zinc and copper on digestive enzyme activity and intestinal morphology in weaned pigs. J. Anim. Sci. 2006, 84:3310-3320.
5. Heo J.M., Kim J.H., Hansen C.F., Mullan B.P., Hampson D.J., Pluske J.R. Feeding a diet with decreased protein content reduces indices of protein fermentation and the incidence of postweaning diarrhea in weaned pigs challenged with an enterotoxigenic strain of Escherichia coli. J. Anim. Sci. 2009, 87:2833-2843.
6. Heo J.M., Opapeju F.O., Pluske J.R., Kim J.C., Hampson D.J., Nyachoti C.M. Gastrointestinal health and function in weaned pigs: a review of feeding strategies to control post-weaning diarrhoea without using in-feed antimicrobial compounds. J. Anim. Physiol. Anim. Nutr. 2013, 97:207-237.
7. Hill G.M. Minerals and mineral utilization in swine. Sustainable Swine Nutrition 2013, 173-195. John Wiley & Sons, Inc., Oxford, UK. L.I. Chiba (Ed.).
8. Hill G.M., Mahan D.C., Carter S.D., Cromwell G.L., Ewan R.C., Harrold R.L., Lewis A.J., Miller P.S., Shurson G.C., Veum T.L. Effect of pharmacological concentrations of zinc oxide with or without the inclusion of an antibacterial agent on nursery pig performance. J. Anim. Sci. 2001, 79:934-941.
9. Hu C.H., Gu L.Y., Luan Z.S., Song J., Zhu K. Effects of montmorillonite-zinc oxide hybrid on performance, diarrhea, intestinal permeability and morphology of weanling pigs. Anim. Feed Sci. Technol. 2012, 177:108-115.
10. Jang I.S., Ko Y.H., Kang S.Y., Lee C.Y. Effect of a commercial essential oil on growth performance, digestive enzyme activity and intestinal microflora population in broiler chickens. Anim. Feed Sci. Technol. 2007, 134:304-315.
11. Jang I.S., Ko Y.H., Yang H.Y., Ha J.S., Kim J.Y., Kim J.Y., Kang S.Y., Yoo D.H., Nam D.S., Kim D.H., Lee C.Y. Influence of essential oil components on growth performance and the functional activity of the pancreas and small intestine in broiler chickens. Asian-Aust. J. Anim. Sci 2004, 17:394-400.
12. Jensen-Waern M., Melin L., Lindberg R., Johannisson A., Petersson L., Wallgren P.P. Dietary zinc oxide in weaned pigs - effects on performance, tissue concentrations, morphology, neutrophil functions and faecal microflora. Res. Vet. Sci. 1998, 64:225-231.
13. Kim J.C., Hansen C.F., Mullan B.P., Pluske J.R. Nutrition and pathology of weaner pigs: nutritional strategies to support barrier function in the gastrointestinal tract. Anim. Feed Sci. Technol. 2012, 173:3-16.
14. Kwon C.-H., Lee C.Y., Han S.-Y., Kim S.-J., Park B.-C., Jang I., Han J.H. Effects of dietary supplementation of lipid-encapsulated zinc oxide on colibacillosis, growth and intestinal morphology in weaned piglets challenged with enterotoxigenic Escherichia coli. Anim. Sci. J. 2014, 85:805-813.
15. Lee C.Y., Lim Y.-W., Ko Y.-H., Kang S.-Y., Park M.J., Ko T., Lee J.H., Hyun Y., Jeong K.-S., Jang I.S. Intestinal growth and development of weanling pigs in response to dietary supplementation of antibiotics, phytogenic products and brewer's yeast plus Bacillus spores. J. Anim. Sci. Technol. 2011, 53:227-235.
16. Li B.T., Van Kessel A.G., Caine W.R., Huang S.X., Kirkwood R.N. Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide. Can. J. Anim. Sci. 2001, 81:511-516.
17. NRC Nutrient Requirements of Swine 1998, National Academy Press, Washington, DC. 10th revised ed.
18. Pekas J.C. Zinc 65 metabolism: gastrointestinal secretion by the pig. Am. J. Physiol. 1966, 211:407-413.
19. SAS SAS/STAT Software for PC. Release 9.2 2008, SAS Institute Inc., Cary, NC, USA.
20. Shen J., Chen Y., Wang Z., Zhou A., He M., Mao L., Zou H., Peng Q., Xue B., Wang L., Zhang X., Wu S., Lv Y. Coated zinc oxide improves intestinal immunity function and regulates microbiota composition in weaned piglets. Br. J. Nutr. 2014, 111:2123-2134.
21. Weary D.M., Jasper J.J., Hotzel M.J. Understanding weaning stress. Appl. Anim. Behav. Sci. 2008, 110:24-41.
22. Zhao P.Y., Jung J.H., Kim I.H. Effect of mannan oligosaccharides and fructan on growth performance, nutrient digestibility, blood profile, and diarrhea score in weanling pigs. J. Anim. Sci. 2012, 90:833-839.