MiR-494 represses HOXA10 expression and inhibits cell proliferation in oral cancer

Oral Oncology

Volumn 51, Issue 2, 2015, Pages 151-157

  Libório Kimura, Tatiana N ^a,b   Jung, Hyun Min ^a,c   Chan, Edward K L ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b FEDERAL UNIVERSITY OF AMAZONAS   (Brazil)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

HOXA10; MicroRNA; miR 375; miR 494; Oral cancer

Indexed keywords

MICRORNA; MICRORNA 494; RNA; TRANSCRIPTION FACTOR HOXA10; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; HOXA10 PROTEIN, HUMAN; MIRN494 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; ADULT; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER TISSUE; CELL PROLIFERATION ASSAY; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION ASSAY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUCIFERASE ASSAY; MOUTH CANCER; MOUTH SQUAMOUS CELL CARCINOMA; ORAL CANCER CELL LINE; PHARYNX CANCER CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN RNA BINDING; REGULATORY MECHANISM; TONGUE CANCER; TONGUE CANCER CELL LINE; TUMOR SUPPRESSOR GENE; CELL PROLIFERATION; GENETICS; METABOLISM; MOUTH TUMOR; PATHOLOGY; PHYSIOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; HOMEODOMAIN PROTEINS; HUMANS; MICRORNAS; MOUTH NEOPLASMS;

EID: 84922637664     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2014.11.019     Document Type: Article

References (40)

1. van der Waal I, de Bree R, Brakenhoff R, Coebergh JW. Early diagnosis in primary oral cancer: is it possible? Med Oral Patol Oral Cir Bucal 2011;16:e300-5.
2. Shiboski CH, Shiboski SC, Silverman Jr S. Trends in oral cancer rates in the United States, 1973-1996. Commun Dent Oral Epidemiol 2000;28:249-56.
3. Ambros V. The functions of animal microRNAs. Nature 2004;431:350-5.
4. Shiiba M, Uzawa K, Tanzawa H. MicroRNAs in head and neck squamous cell carcinoma (HNSCC) and oral squamous cell carcinoma (OSCC). Cancers (Basel) 2010;2:653-69.
5. Wu BH, Xiong XP, Jia J, Zhang WF. MicroRNAs: new actors in the oral cancer scene. Oral Oncol 2011:314-9.
6. Jung HM, Phillips BL, Patel RS, Cohen DM, Jakymiw A, Kong WW, et al. Keratinization-associated miR-7 and miR-21 regulate tumor suppressor reversion-inducing cysteine-rich protein with kazal motifs (RECK) in oral cancer. J Biol Chem 2012;287:29261-72.
7. Jung HM, Patel RS, Phillips BL, Wang H, Cohen DM, Reinhold WC, et al. Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions. Mol Biol Cell 2013;24:1638-48 [S1-7].
8. Jung HM, Phillips BL, Chan EK. MiR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3zeta. Mol Cancer 2014;13:80.
9. Chang SS, Jiang WW, Smith I, Poeta LM, Begum S, Glazer C, et al. MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer 2008;123:2791-7.
10. Ambs S, Prueitt RL, Yi M, Hudson RS, Howe TM, Petrocca F, et al. Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. Cancer Res 2008;68:6162-70.
11. Shen PF, Chen XQ, Liao YC, Chen N, Zhou Q, Wei Q, et al. MicroRNA-494-3p targets CXCR4 to suppress the proliferation, invasion, and migration of prostate cancer. Prostate 2014;74:756-67.
12. Ohdaira H, Sekiguchi M, Miyata K, Yoshida K. MicroRNA-494 suppresses cell proliferation and induces senescence in A549 lung cancer cells. Cell Prolif 2012;45:32-8.
13. Kim WK, Park M, Kim YK, Tae YK, Yang HK, Lee JM, et al. MicroRNA-494 downregulates KIT and inhibits gastrointestinal stromal tumor cell proliferation. Clin Cancer Res 2011;17:7584-94.
14. Yamanaka S, Campbell NR, An F, Kuo SC, Potter JJ, Mezey E, et al. Coordinated effects of microRNA-494 induce G(2)/M arrest in human cholangiocarcinoma. Cell Cycle 2012;11:2729-38.
15. Diakos C, Zhong S, Xiao Y, Zhou M, Vasconcelos GM, Krapf G, et al. TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a. Blood 2010;116:4885-93.
16. Duan H, Jiang Y, Zhang H, Wu Y. MiR-320 and miR-494 affect cell cycles of primary murine bronchial epithelial cells exposed to benzo[a]pyrene. Toxicol In Vitro 2010;24:928-35.
17. Zhao JJ, Yang J, Lin J, Yao N, Zhu Y, Zheng J, et al. Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis. Childs Nerv Syst 2009;25:13-20.
18. Abate-Shen C. Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer 2002;2:777-85.
19. Haria D, Naora H. Homeobox gene deregulation: impact on the hallmarks of cancer. Cancer Hallmark 2013;1:67-76.
20. Nunes FD, de Almeida FC, Tucci R, de Sousa SC. Homeobox genes: a molecular link between development and cancer. Pesqui Odontol Bras 2003;17:94-8.
21. Rodini CO, Xavier FC, Paiva KB, De Souza Setubal Destro MF, Moyses RA, Michaluarte P, et al. Homeobox gene expression profile indicates HOXA5 as a candidate prognostic marker in oral squamous cell carcinoma. Int J Oncol 2012;40:1180-8.
22. De Souza Setubal Destro MF, Bitu CC, Zecchin KG, Graner E, Lopes MA, Kowalski LP, et al. Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis. Int J Oncol 2010;36:141-9.
23. Hassan NM, Hamada J, Murai T, Seino A, Takahashi Y, Tada M, et al. Aberrant expression of HOX genes in oral dysplasia and squamous cell carcinoma tissues. Oncol Res 2006;16:217-24.
24. Libório TN, Acquafreda T, Matizonkas-Antonio LF, Silva-Valenzuela MG, Ferraz AR, Nunes FD. In situ hybridization detection of homeobox genes reveals distinct expression patterns in oral squamous cell carcinomas. Histopathology 2011;58:225-33.
25. Liborio TN, Ferreira EN, Aquino Xavier FC, Carraro DM, Kowalski LP, Soares FA, et al. TGIF1 splicing variant 8 is overexpressed in oral squamous cell carcinoma and is related to pathologic and clinical behavior. Oral Surg Oral Med Oral Pathol Oral Radiol 2013;116:614-25.
26. Matizonkas-Antonio LF, Libório TN, Aquino Xavier FC, Silva-Valenzuela M, Michaluarte-Júnior P, Nunes FD. Detection of TGIF1 homeobox gene in oral squamous cell carcinoma according to histologic grading. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111:218-24.
27. Zhu F, Li J, Li WX, Liu ZC, Long X. Overexpression and clinicopathological significance of homeobox gene Quox-1 in oral squamous cell carcinoma. J Biochem Mol Biol 2004;37:671-5.
28. Yamano Y, Uzawa K, Shinozuka K, Fushimi K, Ishigami T, Nomura H, et al. Hyaluronan-mediated motility: a target in oral squamous cell carcinoma. Int J Oncol 2008;32:1001-9.
29. Yamatoji M, Kasamatsu A, Yamano Y, Sakuma K, Ogoshi K, Iyoda M, et al. State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma. Oncol Rep 2010;23:61-7.
30. Jakymiw A, Patel RS, Deming N, Bhattacharyya I, Shah P, Lamont RJ, et al. Overexpression of dicer as a result of reduced let-7 microRNA levels contributes to increased cell proliferation of oral cancer cells. Genes Chromosom Cancer 2010;49:549-59.
31. Lian SL, Li S, Abadal GX, Pauley BA, Fritzler MJ, Chan EKL. The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing. RNA 2009;15:804-13.
32. Yao B, Li S, Jung HM, Lian SL, Abadal GX, Han F, et al. Divergent GW182 functional domains in the regulation of translational silencing. Nucleic Acids Res 2011;39:2534-47.
33. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001;29:e45.
34. Friedman RC, Farh KK, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009;19:92-105.
35. Nagadia R, Pandit P, Coman WB, Cooper-White J, Punyadeera C. MiRNAs in head and neck cancer revisited. Cell Oncol (Dordr) 2013;36:1-7.
36. He W, Li Y, Chen X, Lu L, Tang B, Wang Z, et al. miR-494 acts as an antioncogene in gastric carcinoma by targeting c-myc. J Gastroenterol Hepatol 2014.
37. Ries J, Vairaktaris E, Agaimy A, Kintopp R, Baran C, Neukam FW, et al. MiR-186, miR-3651 and miR-494: potential biomarkers for oral squamous cell carcinoma extracted from whole blood. Oncol Rep 2014;31:1429-36.
38. Junttila MR, Puustinen P, Niemela M, Ahola R, Arnold H, Bottzauw T, et al. CIP2A inhibits PP2A in human malignancies. Cell 2007;130:51-62.
39. Pereira MCMC. Biological role of HOXA10 homeobox gene in oral squamous cell carcinoma Piracicaba: Universidade Estadual de Campinas; 2012.
40. Lu Z, Hardt J, Kim JJ. Global analysis of genes regulated by HOXA10 in decidualization reveals a role in cell proliferation. Mol Hum Reprod 2008;14:357-66.