Heterogeneity in Kv7 channel function in the cerebral and coronary circulation

Microcirculation

Volumn 22, Issue 2, 2015, Pages 109-121

  Lee, Sewon ^a,b   Yang, Yan ^a   Tanner, Miles A ^a   Li, Min ^a   Hill, Michael A ^a,c  

^a UNIVERSITY OF MISSOURI   (United States)

^b SolarLight Ltd   (South Korea)

^c University of Missouri   (United States)

Author keywords

Cerebral and coronary arteries; Electrophysiology; K+ channels; Pharmacological manipulation; Regional heterogeneity; Voltage gated K+ channels

Indexed keywords

FORSKOLIN; LINOPIRDINE; POTASSIUM CHANNEL KCNQ4; RETIGABINE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL KV7; VOLTAGE GATED POTASSIUM CHANNEL KV7.1; CARBAMIC ACID DERIVATIVE; INDOLE DERIVATIVE; KCNQ1 PROTEIN, MOUSE; KCNQ4 PROTEIN, MOUSE; PHENYLENEDIAMINE DERIVATIVE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KCNQ; POTASSIUM CHANNEL KCNQ1; PYRIDINE DERIVATIVE; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASILAR ARTERY; BLOOD VESSEL REACTIVITY; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; BRAIN CIRCULUS ARTERIOSUS; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; POTASSIUM CURRENT; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTILITY; VASCULAR SMOOTH MUSCLE; VASODILATATION; WESTERN BLOTTING; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIBODY SPECIFICITY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; VASOCONSTRICTION;

ANIMALS; BASILAR ARTERY; CARBAMATES; CEREBROVASCULAR CIRCULATION; CIRCLE OF WILLIS; COLFORSIN; CORONARY CIRCULATION; INDOLES; KCNQ POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; MALE; MICE; MICE, KNOCKOUT; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; ORGAN SPECIFICITY; PHENYLENEDIAMINES; POTASSIUM CHANNEL BLOCKERS; PYRIDINES; VASOCONSTRICTION; VASODILATION; VASODILATOR AGENTS;

EID: 84922633783     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1111/micc.12183     Document Type: Article

References (41)

1. Afeli SA, Malysz J, Petkov GV. Molecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscle. PLoS ONE 8: e75875, 2013.
2. Amberg GC, Santana LF. Kv2 channels oppose myogenic constriction of rat cerebral arteries. Am J Physiol Cell Physiol 291: C348-C356, 2006.
3. Berwick ZC, Dick GM, Moberly SP, Kohr MC, Sturek M, Tune JD. Contribution of voltage-dependent K(+) channels to metabolic control of coronary blood flow. J Mol Cell Cardiol 52: 912-919, 2012.
4. 2+ channels to coronary pressure-flow autoregulation. Basic Res Cardiol 107: 264, 2012.
5. Brueggemann LI, Mackie AR, Cribbs LL, Freda J, Tripathi A, Majetschak M, Byron KL. Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels. J Biol Chem 289: 2099-2111, 2014.
6. Chadha PS, Jepps TA, Carr G, Stott JB, Zhu HL, Cole WC, Greenwood IA. Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related peptide-induced cerebral reactivity. Arterioscler Thromb Vasc Biol 34: 887-893, 2014.
7. Chadha PS, Zunke F, Davis AJ, Jepps TA, Linders JT, Schwake M, Towart R, Greenwood IA. Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries. Br J Pharmacol 166: 1377-1387, 2012.
8. Chadha PS, Zunke F, Zhu HL, Davis AJ, Jepps TA, Olesen SP, Cole WC, Moffatt JD, Greenwood IA. Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired beta-adrenoceptor-mediated relaxation of renal arteries in hypertension. Hypertension 59: 877-884, 2012.
9. Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, Thomas-Tikhonenko A, Mendell JT. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci USA 106: 3384-3389, 2009.
10. Davis MJ, Hill MA. Signaling mechanisms underlying the vascular myogenic response. Physiol Rev 79: 387-423, 1999.
11. Dettman EJ, Simko SJ, Ayanga B, Carofino BL, Margolin JF, Morse HC 3rd, Justice MJ. Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors. Oncogene 30: 2859-2873, 2011.
12. + channels regulate the duration of reactive hyperemia in the canine coronary circulation. Am J Physiol Heart Circ Physiol 294: H2371-H2381, 2008.
13. Gollasch M. KCNQ channels and novel insights into coronary perfusion. Hypertension 62: 1011-1012, 2013.
14. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinett MC, Stuhmer W, Wang X. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol Rev 57: 473-508, 2005.
15. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391: 85-100, 1981.
16. Jackson WF. Potassium channels in the peripheral microcirculation. Microcirculation 12: 113-127, 2005.
17. + channel dysfunction in myocytes from a dog model of subarachnoid hemorrhage. J Cereb Blood Flow Metab 28: 797-811, 2008.
18. Jepps TA, Chadha PS, Davis AJ, Harhun MI, Cockerill GW, Schmitt N, Greenwood IA, Olesen SP. Downregulation of Kv7.4 channel activity in primary and secondary hypertension. Circulation 124: 602-611, 2011.
19. Khanamiri S, Soltysinska E, Jepps TA, Bentzen BH, Chadha PS, et al. Contribution of kv7 channels to Basal coronary flow and active response to ischemia. Hypertension 62: 1090-1097, 2013.
20. Klein LW, Weintraub WS, Agarwal JB, Schneider RM, Seelaus PA, Katz RI, Helfant RH. Prognostic significance of severe narrowing of the proximal portion of the left anterior descending coronary artery. Am J Cardiol 58: 42-46, 1986.
21. + channels in rabbit myogenic cerebral arteries. Am J Physiol 269: H348-H355, 1995.
22. + channels in vascular smooth muscle cells: modulation by protein kinases. Prog Biophys Mol Biol 103: 95-101, 2010.
23. Korovkina VP, England SK. Detection and implications of potassium channel alterations. Vascul Pharmacol 38: 3-12, 2002.
24. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408, 2001.
25. Lossos IS, Czerwinski DK, Wechser MA, Levy R. Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies. Leukemia 17: 789-795, 2003.
26. Main MJ, Cryan JE, Dupere JR, Cox B, Clare JJ, Burbridge SA. Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine. Mol Pharmacol 58: 253-262, 2000.
27. Mani BK, Brueggemann LI, Cribbs LL, Byron KL. Activation of vascular KCNQ (Kv7) potassium channels reverses spasmogen-induced constrictor responses in rat basilar artery. Br J Pharmacol 164: 237-249, 2011.
28. Mani BK, O'Dowd J, Kumar L, Brueggemann LI, Ross M, Byron KL. Vascular KCNQ (Kv7) potassium channels as common signaling intermediates and therapeutic targets in cerebral vasospasm. J Cardiovasc Pharmacol 61: 51-62, 2013.
29. McCallum LA, Pierce SL, England SK, Greenwood IA, Tribe RM. The contribution of Kv7 channels to pregnant mouse and human myometrial contractility. J Cell Mol Med 15: 577-586, 2011.
30. Cipolla MJ. The Cerebral Circulation. San Rafael, CA: Morgan & Claypool Life Sciences, 2009.
31. Mulvany MJ, Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 41: 19-26, 1977.
32. Nelson MT, Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 268: C799-C822, 1995.
33. + channel KCNQ genes in human arteries. Br J Pharmacol 162: 42-53, 2011.
34. Plane F, Johnson R, Kerr P, Wiehler W, Thorneloe K, Ishii K, Chen T, Cole WC. Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter. Circ Res 96: 216-224, 2005.
35. + channel sensitivity to the anticonvulsant retigabine. J Neurosci 25: 5051-5060, 2005.
36. Svalo J, Bille M, Parameswaran Theepakaran N, Sheykhzade M, Nordling J, Bouchelouche P. Bladder contractility is modulated by Kv7 channels in pig detrusor. Eur J Pharmacol 715: 312-320, 2013.
37. Wuttke TV, Seebohm G, Bail S, Maljevic S, Lerche H. The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate. Mol Pharmacol 67: 1009-1017, 2005.
38. Ca: involvement of the beta1-subunit. J Physiol 587: 3025-3044, 2009.
39. 2+ sensitivity of BK(Ca) current in arteriolar smooth muscle. J Physiol 591: 1277-1293, 2013.
40. Yeung SY, Pucovsky V, Moffatt JD, Saldanha L, Schwake M, Ohya S, Greenwood IA. Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity. Br J Pharmacol 151: 758-770, 2007.
41. Zhong XZ, Harhun MI, Olesen SP, Ohya S, Moffatt JD, Cole WC, Greenwood IA. Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter. J Physiol 588: 3277-3293, 2010.