Contribution of voltage-dependent K+ and Ca2+ channels to coronary pressure-flow autoregulation

Basic Research in Cardiology

Volumn 107, Issue 3, 2012, Pages

  Berwick, Zachary C ^a   Moberly, Steven P ^a   Kohr, Meredith C ^a   Morrical, Ethan B ^a   Kurian, Michelle M ^a   Dick, Gregory M ^b   Tune, Johnathan D ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoregulation; Calcium channel; Coronary blood flow; Potassium channel; Swine

Indexed keywords

CALCIUM CHANNEL CAV1.2; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; L TYPE CALCIUM CHANNEL ALPHA(1C); L-TYPE CALCIUM CHANNEL ALPHA(1C); POTASSIUM CHANNEL BLOCKING AGENT; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR AUTOREGULATION; CHANNEL GATING; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; CORONARY ARTERY PRESSURE; CORONARY VASCULAR RESISTANCE; HEART LEFT VENTRICLE CONTRACTILITY; HEART MUSCLE OXYGEN CONSUMPTION; IN VIVO STUDY; NONHUMAN; PROTEIN FUNCTION; SWINE; ANIMAL; BLOOD PRESSURE; CORONARY BLOOD VESSEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HEART CONTRACTION; HEART MUSCLE; HEART VENTRICLE FUNCTION; HOMEOSTASIS; MECHANOTRANSDUCTION; METABOLISM; MICROCIRCULATION; OXYGEN CONSUMPTION; TIME; VASCULAR RESISTANCE; VASODILATATION;

ANIMALS; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CORONARY CIRCULATION; CORONARY VESSELS; DOSE-RESPONSE RELATIONSHIP, DRUG; HOMEOSTASIS; MECHANOTRANSDUCTION, CELLULAR; MICROCIRCULATION; MYOCARDIAL CONTRACTION; MYOCARDIUM; OXYGEN CONSUMPTION; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; SWINE; TIME FACTORS; VASCULAR RESISTANCE; VASODILATION; VASODILATOR AGENTS; VENTRICULAR FUNCTION;

EID: 84858974466     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-012-0264-6     Document Type: Article

References (69)

1. Ahmed A, Waters CM, Leffler CW, Jaggar JH (2004) Ionic mechanisms mediating the myogenic response in newborn porcine cerebral arteries. Am J Physiol Heart Circ Physiol 287: H2061-H2069. doi:10.1152/ajpheart.00660.2004 (Pubitemid 39433391)
2. Bai XJ, Iwamoto T, Williams AG Jr, Fan WL, Downey HF (1994) Coronary pressure-flow autoregulation protects myocardium from pressure-induced changes in oxygen consumption. Am J Physiol 266:H2359-H2368 (Pubitemid 24215867)
3. Bassenge E, Heusch G (1990) Endothelial and neuro-humoral control of coronary blood flow in health and disease. Rev Physiol Biochem Pharmacol 116:77-165. doi:10.1007/3540528806-4
4. Berwick ZC, Dick GM, Moberly SP, Kohr MC, Sturek M, Tune JD (2011) Contribution of voltage-dependent K(+) channels to metabolic control of coronary blood flow. J Mol Cell Cardiol. doi:10.1016/j.yjmcc.2011.07.004
5. Berwick ZC, Payne GA, Lynch B, Dick GM, Sturek M, Tune JD (2010) Contribution of adenosine A(2A) and A(2B) receptors to ischemic coronary dilation: role of K(V) and K(ATP) channels. Microcirculation 17:600-607. doi:10.1111/j.1549-8719.2010. 00054.x
6. Borbouse L, Dick GM, Payne GA, Berwick ZC, Neeb ZP, Alloosh M, Bratz IN, Sturek M, Tune JD (2010) Metabolic syndrome reduces the contribution of K + channels to ischemic coronary vasodilation. Am J Physiol Heart Circ Physiol 298: H1182-H1189. doi:10.1152/ajpheart.00888.2009
7. Brading AF, Burdyga TV, Scripnyuk ZD (1983) The effects of papaverine on the electrical and mechanical activity of the guinea-pig ureter. J Physiol 334:79-89 (Pubitemid 13176084)
8. Bratz IN, Swafford AN Jr, Kanagy NL, Dick GM (2005) Reduced functional expression of K(+) channels in vascular smooth muscle cells from rats made hypertensive with N{omega}-nitro-L-arginine. Am J Physiol Heart Circ Physiol 289:H1284-H1290. doi:10.1152/ajpheart.01053.2004 (Pubitemid 41208974)
9. Broten TP, Feigl EO (1992) Role of myocardial oxygen and carbon dioxide in coronary autoregulation. Am J Physiol 262: H1231-H1237
10. Canty JM Jr, Smith TP Jr (1995) Modulation of coronary autoregulatory responses by endothelium-derived nitric oxide. Int J Cardiol 50:207-215. doi:10.1016/0167-5273(95)02379-B
11. Canty JM Jr, Suzuki G (2011) Myocardial perfusion and contraction in acute ischemia and chronic ischemic heart disease. J Mol Cell Cardiol. doi:10.1016/j.yjmcc.2011.08.019
12. Davis MJ, Hill MA (1999) Signaling mechanisms underlying the vascular myogenic response. Physiol Rev 79:387-423 (Pubitemid 29210926)
13. Davis MJ, Meininger GA, Zawieja DC (1992) Stretch-induced increases in intracellular calcium of isolated vascular smooth muscle cells. Am J Physiol 263:H1292-H1299
14. DeFily DV, Chilian WM (1995) Coronary microcirculation: autoregulation and metabolic control. Basic Res Cardiol 90: 112-118. doi:10.1007/BF00789441
15. Dick GM, Bratz IN, Borbouse L, Payne GA, Dincer UD, Knudson JD, Rogers PA, Tune JD (2008) Voltage-dependent K + channels regulate the duration of reactive hyperemia in the canine coronary circulation. Am J Physiol Heart Circ Physiol 294:H2371-H2381. doi:10.1152/ajpheart.01279.2007
16. Dole WP (1987) Autoregulation of the coronary circulation. Prog Cardiovasc Dis 29:293-323. doi:10.1016/S0033-0620(87)80005-1 (Pubitemid 17015399)
17. Dole WP, Nuno DW (1986) Myocardial oxygen tension determines the degree and pressure range of coronary autoregulation. Circ Res 59:202-215. doi:10.1161/01.RES.59.2.202 (Pubitemid 16017875)
18. Driscol TE, Moir TW, Eckstein RW (1964) Autoregulation of coronary blood flow: effect of interarterial pressure gradients. Circ Res 15:103-111
19. Duncker DJ, Bache RJ (2008) Regulation of coronary blood flow during exercise. Physiol Rev 88:1009-1086
20. Ebeigbe AB, Aloamaka CP (1985) Mechanism of hydralazineinduced relaxation of arterial smooth muscle. Cardiovasc Res 19:400-405 (Pubitemid 15033667)
21. Feigl EO (1983) Coronary physiology. Physiol Rev 63:1-205 (Pubitemid 13188482)
22. Feigl EO (1989) Coronary autoregulation. J Hypertens Suppl 7: S55-S58 (Pubitemid 19265012)
23. Feigl EO, Neat GW, Huang AH (1990) Interrelations between coronary artery pressure, myocardial metabolism and coronary blood flow. J Mol Cell Cardiol 22:375-390. doi:10.1016/0022-2828(90)91474-L (Pubitemid 20195698)
24. Gregg DE (1963) Effect of coronary perfusion pressure or coronary flow on oxygen usage of the myocardium. Circ Res 13: 497-500. doi:10.1161/01.RES.13.6. 497
25. Heaps CL, Jeffery EC, Laine GA, Price EM, Bowles DK (2008) Effects of exercise training and hypercholesterolemia on adenosine activation of voltage-dependent K + channels in coronary arterioles. J Appl Physiol 105:1761-1771. doi:10.1152/ japplphysiol.90958.2008
26. Heaps CL, Tharp DL, Bowles DK (2005) Hypercholesterolemia abolishes voltage-dependent K + channel contribution to adenosine-mediated relaxation in porcine coronary arterioles. Am J Physiol Heart Circ Physiol 288:H568-H576. doi:10.1152/ ajpheart.00157.2004 (Pubitemid 40139639)
27. Herlihy JT, Bockman EL, Berne RM, Rubio R (1976) Adenosine relaxation of isolated vascular smooth muscle. Am J Physiol 230: 1239-1243
28. Heusch G (2010) Adenosine and maximum coronary vasodilation in humans: myth and misconceptions in the assessment of coronary reserve. Basic Res Cardiol 105:1-5. doi:10.1007/s00395-009-0074-7
29. Hill MA, Davis MJ, Meininger GA, Potocnik SJ, Murphy TV (2006) Arteriolar myogenic signalling mechanisms: implications for local vascular function. Clin Hemorheol Microcirc 34:67-79 (Pubitemid 43351012)
30. Hinshaw LB (1964) Mechanism of renal autoregulation: role of tissue pressure and description of a multifactor hypothesis. Circ Res (suppl 15):120-131
31. Ishikawa T, Hume JR, Keef KD (1993) Regulation of Ca2 ? channels by cAMP and cGMP in vascular smooth muscle cells. Circ Res 73:1128-1137. doi:10.1161/01.RES.73.6.1128
32. Johnson PC (1964) Review of previous studies and current theories of autoregulation. Circ Res (suppl 15):2-9
33. Johnson PC, Waugh WH, Hinshaw LB (1963) Autoregulation of Blood Flow. Science 140:203-207
34. Jones CJ, Kuo L, Davis MJ, Chilian WM (1993) Myogenic and flow-dependent control mechanisms in the coronary microcirculation. Basic Res Cardiol 88:2-10. doi:10.1007/BF00788525 (Pubitemid 23083865)
35. Kauser K, Stekiel WJ, Rubanyi G, Harder DR (1989) Mechanism of action of EDRF on pressurized arteries: effect on K + conductance. Circ Res 65:199-204. doi:10.1161/01.RES.65.1.199 (Pubitemid 19173147)
36. Knudson JD, Dincer UD, Bratz IN, Sturek M, Dick GM, Tune JD (2007) Mechanisms of coronary dysfunction in obesity and insulin resistance. Microcirculation 14:317-338. doi:10.1080/ 10739680701282887 (Pubitemid 47050025)
37. Komaru T, Lamping KG, Dellsperger KC (1994) Role of adenosine in vasodilation of epimyocardial coronary microvessels during reduction in perfusion pressure. J Cardiovasc Pharmacol 24:434-442 (Pubitemid 24260524)
38. Krajcar M, Heusch G (1993) Local and neurohumoral control of coronary blood flow. Basic Res Cardiol 88(Suppl 1):25-42 (Pubitemid 23226437)
39. Kuo L, Chilian WM, Davis MJ (1990) Coronary arteriolar myogenic response is independent of endothelium. Circ Res 66:860-866. doi:10.1161/01.RES.66.3.860 (Pubitemid 20086923)
40. Kuo L, Chilian WM, Davis MJ (1991) Interaction of pressureand flow-induced responses in porcine coronary resistance vessels. Am J Physiol 261:H1706-H1715
41. Kuo L, Davis MJ, Chilian WM (1988) Myogenic activity in isolated subepicardial and subendocardial coronary arterioles. Am J Physiol 255:H1558-H1562
42. Laird JD, Breuls PN, van der MP, Spaan JA (1981) Can a single vasodilator be responsible for both coronary autoregulation and metabolic vasodilation?. Basic Res Cardiol 76:354-358 doi: 10.1007/BF01908321 (Pubitemid 11042607)
43. Li H, Chai Q, Gutterman DD, Liu Y (2003) Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells. Am J Physiol Heart Circ Physiol 285:H1213-H1219. doi:10.1152/ajpheart.00226. 2003 (Pubitemid 37048179)
44. Liu Y, Bubolz AH, Mendoza S, Zhang DX, Gutterman DD (2011) H2O2 is the transferrable factor mediating flow-induced dilation in human coronary arterioles. Circ Res 108:566-573. doi: 10.1161/CIRCRESAHA.110.237636
45. Liu Y, Gutterman DD (2009) Vascular control in humans: focus on the coronary microcirculation. Basic Res Cardiol 104:211-227. doi:10.1007/s00395- 009-0775-y
46. Liu Y, Gutterman DD (2002) The coronary circulation in diabetes: influence of reactive oxygen species on K + channelmediated vasodilation. Vascul Pharmacol 38:43-49. doi:10.1016/ S1537-1891(02)00125-8
47. Liu Y, Terata K, Rusch NJ, Gutterman DD (2001) High glucose impairs voltage-gated K(+) channel current in rat small coronary arteries. Circ Res 89:146-152. doi:10.1161/hh1401.093294 (Pubitemid 34135822)
48. McHale PA, Dube GP, Greenfield JC Jr (1987) Evidence for myogenic vasomotor activity in the coronary circulation. Prog Cardiovasc Dis 30:139-146. doi:10.1016/0033-0620(87)90006-5 (Pubitemid 17130526)
49. Miller FJ Jr, Dellsperger KC, Gutterman DD (1997) Myogenic constriction of human coronary arterioles. Am J Physiol 273: H257-H264
50. Nelson MT, Patlak JB, Worley JF, Standen NB (1990) Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. Am J Physiol 259:C3-C18 (Pubitemid 20229864)
51. Osher WJ (1953) Pressure-flow relationship of the coronary system. Am J Physiol 172:403-416
52. Pesic A, Madden JA, Pesic M, Rusch NJ (2004) High blood pressure upregulates arterial L-type Ca2 ? channels: is membrane depolarization the signal? Circ Res 94:e97-e104. doi: 10.1161/01.RES.0000131495.93500.3c
53. Pratt PF, Bonnet S, Ludwig LM, Bonnet P, Rusch NJ (2002) Upregulation of L-type Ca2 ? channels in mesenteric and skeletal arteries of SHR. Hypertension 40:214-219. doi:10.1161/01. HYP.0000025877.23309.36 (Pubitemid 34840101)
54. Rogers PA, Chilian WM, Bratz IN, Bryan RM Jr, Dick GM (2007) H2O2 activates redox-and 4-aminopyridine-sensitive Kv channels in coronary vascular smooth muscle. Am J Physiol Heart Circ Physiol 292:H1404-H1411. doi:10.1152/ajpheart. 00696.2006 (Pubitemid 46377128)
55. Rogers PA, Dick GM, Knudson JD, Focardi M, Bratz IN, Swafford AN Jr, Saitoh S, Tune JD, Chilian WM (2006) H2O2-induced redox-sensitive coronary vasodilation is mediated by 4-aminopyridine-sensitive K + channels. Am J Physiol Heart Circ Physiol 291:H2473-H2482. doi:10.1152/ajpheart.00172. 2006
56. Saitoh S, Zhang C, Tune JD, Potter B, Kiyooka T, Rogers PA, Knudson JD, Dick GM, Swafford A, Chilian WM (2006) Hydrogen peroxide: a feed-forward dilator that couples myocardial metabolism to coronary blood flow. Arterioscler Thromb Vasc Biol 26:2614-2621. doi:10.1161/01.ATV.0000249408. 55796.da
57. Schrader J, Haddy FJ, Gerlach E (1977) Release of adenosine, inosine and hypoxanthine from the isolated guinea pig heart during hypoxia, flow-autoregulation and reactive hyperemia. Pflugers Arch 369:1-6. doi:10.1007/BF00580802 (Pubitemid 8095711)
58. Schulz R, Guth BD, Heusch G (1991) No effect of coronary perfusion on regional myocardial function within the autoregulatory range in pigs. Evidence against the Gregg phenomenon. Circulation 83:1390-1403. doi:10.1161/01.CIR.83.4. 1390
59. Setty S, Sun W, Tune JD (2003) Coronary blood flow regulation in the prediabetic metabolic syndrome. Basic Res Cardiol 98:416-423. doi:10.1007/s00395-003-0418-7 (Pubitemid 37336629)
60. Smith TP Jr, Canty JM Jr 1993) Modulation of coronary autoregulatory responses by nitric oxide. Evidence for flowdependent resistance adjustments in conscious dogs. Circ Res 73:232-240. doi:10.1161/01.RES.73.2.232
61. Stepp DW, Kroll K, Feigl EO (1997) K + ATP channels and adenosine are not necessary for coronary autoregulation. Am J Physiol 273:H1299-H1308
62. Tare M, Parkington HC, Coleman HA, Neild TO, Dusting GJ (1990) Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium. Nature 346:69-71. doi:10.1038/346069a0 (Pubitemid 20213940)
63. Thorneloe KS, Nelson MT (2005) Ion channels in smooth muscle: regulators of intracellular calcium and contractility. Can J Physiol Pharmacol 83:215-242. doi:10.1139/Y05-016 (Pubitemid 40942310)
64. Warltier DC, Hardman HF, Gross GJ (1979) Transmural perfusion gradients distal to various degrees of coronary artery stenosis during resting flow or at maximal vasodilation. Basic Res Cardiol 74:494-508. doi:10.1007/BF01907643 (Pubitemid 10201287)
65. Weisfeldt ML, Shock NW (1970) Effect of perfusion pressure on coronary flow and oxygen usage of nonworking heart. Am JPhysiol 218:95-101
66. Wong AY, Klassen GA (1991) Vasomotor coronary oscillations: a model to evaluate autoregulation. Basic Res Cardiol 86:461-475. doi:10.1007/BF02190714
67. Wu GB, Zhou EX, Qing DX, Li J (2009) Role of potassium channels in regulation of rat coronary arteriole tone. Eur JPharmacol 620:57-62. doi:10.1016/j.ejphar.2009.08.004
68. Yada T, Shimokawa H, Hiramatsu O, Kajita T, Shigeto F, Goto M, Ogasawara Y, Kajiya F (2003) Hydrogen peroxide, an endogenous endothelium-derived hyperpolarizing factor, plays an important role in coronary autoregulation in vivo. Circulation 107:1040-1045. doi:10.1161/01.CIR.0000050145.25589.65 (Pubitemid 36258729)
69. Zhang DX, Borbouse L, Gebremedhin D, Mendoza SA, Zinkevich NS, Li R, Gutterman DD (2012) H2O2-Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca2 ? -Activated K + Channel Activation. Circ Res 110:471-480. doi:10.1161/CIRCRESAHA. 111.258871