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Volumn 5, Issue , 2014, Pages

The Wilms tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; STEM CELL FACTOR RECEPTOR; TAMOXIFEN; TUMOR SUPPRESSOR PROTEIN; WT1 PROTEIN; SMALL INTERFERING RNA;

EID: 84922621741     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6852     Document Type: Article
Times cited : (70)

References (67)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman, J. Tumor angiogenesis: therapeutic implications. New Engl. J. Med. 285, 1182-1186 (1971).
    • (1971) New Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 3
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet, P. & Jain, R. K. Molecular mechanisms and clinical applications of angiogenesis. Nature 473, 298-307 (2011).
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 4
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • Casanovas, O., Hicklin, D. J., Bergers, G. & Hanahan, D. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8, 299-309 (2005).
    • (2005) Cancer Cell , vol.8 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 5
    • 60649087564 scopus 로고    scopus 로고
    • Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
    • Ebos, J. M. et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15, 232-239 (2009).
    • (2009) Cancer Cell , vol.15 , pp. 232-239
    • Ebos, J.M.1
  • 6
    • 24944587964 scopus 로고    scopus 로고
    • Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
    • De Palma, M. et al. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell 8, 211-226 (2005).
    • (2005) Cancer Cell , vol.8 , pp. 211-226
    • De Palma, M.1
  • 7
    • 79953750307 scopus 로고    scopus 로고
    • Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
    • Mazzieri, R. et al. Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell 19, 512-526 (2011).
    • (2011) Cancer Cell , vol.19 , pp. 512-526
    • Mazzieri, R.1
  • 8
    • 67651160649 scopus 로고    scopus 로고
    • CD4(\+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • DeNardo, D. G. et al. CD4(\+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16, 91-102 (2009).
    • (2009) Cancer Cell , vol.16 , pp. 91-102
    • Denardo, D.G.1
  • 9
    • 45949096604 scopus 로고    scopus 로고
    • The Wilms' tumour suppressor WT1 is involved in endothelial cell proliferation and migration: Expression in tumour vessels in vivo
    • Wagner, N., Michiels, J. F., Schedl, A. & Wagner, K. D. The Wilms' tumour suppressor WT1 is involved in endothelial cell proliferation and migration: expression in tumour vessels in vivo. Oncogene 27, 3662-3672 (2008).
    • (2008) Oncogene , vol.27 , pp. 3662-3672
    • Wagner, N.1    Michiels, J.F.2    Schedl, A.3    Wagner, K.D.4
  • 10
    • 0025288793 scopus 로고
    • An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
    • Haber, D. A. et al. An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell 61, 1257-1269 (1990).
    • (1990) Cell , vol.61 , pp. 1257-1269
    • Haber, D.A.1
  • 11
    • 33749031535 scopus 로고    scopus 로고
    • The many facets of the Wilms' tumour gene, WT1
    • Hohenstein, P. & Hastie, N. D. The many facets of the Wilms' tumour gene, WT1. Hum. Mol. Genet. 15, R196-R201 (2006).
    • (2006) Hum. Mol. Genet. , vol.15 , pp. R196-R201
    • Hohenstein, P.1    Hastie, N.D.2
  • 13
    • 0027182741 scopus 로고
    • WT-1 is required for early kidney development
    • Kreidberg, J. A. et al. WT-1 is required for early kidney development. Cell 74, 679-691 (1993).
    • (1993) Cell , vol.74 , pp. 679-691
    • Kreidberg, J.A.1
  • 14
    • 0036329040 scopus 로고    scopus 로고
    • WT1 immunoreactivity in uterine papillary serous carcinomas is different from ovarian serous carcinomas
    • Goldstein, N. S. & Uzieblo, A. WT1 immunoreactivity in uterine papillary serous carcinomas is different from ovarian serous carcinomas. Am. J. Clin. Pathol. 117, 541-545 (2002).
    • (2002) Am. J. Clin. Pathol. , vol.117 , pp. 541-545
    • Goldstein, N.S.1    Uzieblo, A.2
  • 15
    • 37249001841 scopus 로고    scopus 로고
    • The Wilms' tumor suppressor WT1 is associated with melanoma proliferation
    • Wagner, N., Panelos, J., Massi, D. & Wagner, K. D. The Wilms' tumor suppressor WT1 is associated with melanoma proliferation. Pflugers Arch. 455, 839-847 (2008).
    • (2008) Pflugers Arch. , vol.455 , pp. 839-847
    • Wagner, N.1    Panelos, J.2    Massi, D.3    Wagner, K.D.4
  • 16
    • 34447634119 scopus 로고    scopus 로고
    • The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis
    • Hosen, N. et al. The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis. Leukemia 21, 1783-1791 (2007).
    • (2007) Leukemia , vol.21 , pp. 1783-1791
    • Hosen, N.1
  • 17
    • 73349108404 scopus 로고    scopus 로고
    • Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
    • Martnez-Estrada, O. M. et al. Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat. Genet. 42, 89-93 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 89-93
    • Martnez-Estrada, O.M.1
  • 18
    • 0036687898 scopus 로고    scopus 로고
    • Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements
    • Forde, A., Constien, R., Grone, H. J., Hammerling, G. & Arnold, B. Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements. Genesis 33, 191-197 (2002).
    • (2002) Genesis , vol.33 , pp. 191-197
    • Forde, A.1    Constien, R.2    Grone, H.J.3    Hammerling, G.4    Arnold, B.5
  • 19
    • 33845357881 scopus 로고    scopus 로고
    • VE-cadherin-CreERT2 transgenic mouse: A model for inducible recombination in the endothelium
    • Monvoisin, A. et al. VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium. Dev. Dyn. 235, 3413-3422 (2006).
    • (2006) Dev. Dyn. , vol.235 , pp. 3413-3422
    • Monvoisin, A.1
  • 20
    • 79955006478 scopus 로고    scopus 로고
    • Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion
    • Coffelt, S. B. et al. Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion. J. Immunol. 186, 4183-4190 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 4183-4190
    • Coffelt, S.B.1
  • 21
    • 0242691647 scopus 로고    scopus 로고
    • Histologic assessment of non-small cell lung carcinoma after neoadjuvant therapy
    • Liu-Jarin, X. et al. Histologic assessment of non-small cell lung carcinoma after neoadjuvant therapy. Mod. Pathol. 16, 1102-1108 (2003).
    • (2003) Mod. Pathol. , vol.16 , pp. 1102-1108
    • Liu-Jarin, X.1
  • 22
    • 0142211270 scopus 로고    scopus 로고
    • A new histological grading system to assess response of breast cancers to primary chemotherapy: Prognostic significance and survival
    • Ogston, K. N. et al. A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival. Breast 12, 320-327 (2003).
    • (2003) Breast , vol.12 , pp. 320-327
    • Ogston, K.N.1
  • 23
    • 35548932872 scopus 로고    scopus 로고
    • A global doublefluorescent Cre reporter mouse
    • Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L. & Luo, L. A global doublefluorescent Cre reporter mouse. Genesis 45, 593-605 (2007).
    • (2007) Genesis , vol.45 , pp. 593-605
    • Muzumdar, M.D.1    Tasic, B.2    Miyamichi, K.3    Li, L.4    Luo, L.5
  • 25
    • 10344255635 scopus 로고    scopus 로고
    • CD107a as a functional marker for the identification of natural killer cell activity
    • Alter, G., Malenfant, J. M. & Altfeld, M. CD107a as a functional marker for the identification of natural killer cell activity. J. Immunol. Methods 294, 15-22 (2004).
    • (2004) J. Immunol. Methods , vol.294 , pp. 15-22
    • Alter, G.1    Malenfant, J.M.2    Altfeld, M.3
  • 26
    • 57349092199 scopus 로고    scopus 로고
    • Relationship between CD107a expression and cytotoxic activity
    • Aktas, E., Kucuksezer, U. C., Bilgic, S., Erten, G. & Deniz, G. Relationship between CD107a expression and cytotoxic activity. Cell. Immunol. 254, 149-154 (2009).
    • (2009) Cell. Immunol. , vol.254 , pp. 149-154
    • Aktas, E.1    Kucuksezer, U.C.2    Bilgic, S.3    Erten, G.4    Deniz, G.5
  • 27
    • 0002474463 scopus 로고
    • Spectrophotometric studies: II. Preparations from washed blood cells; Nitric oxide hemoglobin and sulfhemoglobin
    • Drabkin, D. L. & Austin, J. H. Spectrophotometric studies: II. preparations from washed blood cells; nitric oxide hemoglobin and sulfhemoglobin. J. Biol. Chem. 112, 51-65 (1935).
    • (1935) J. Biol. Chem. , vol.112 , pp. 51-65
    • Drabkin, D.L.1    Austin, J.H.2
  • 28
    • 27644504635 scopus 로고    scopus 로고
    • Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1
    • Wagner, N. et al. Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1. Genes Dev. 19, 2631-2642 (2005).
    • (2005) Genes Dev. , vol.19 , pp. 2631-2642
    • Wagner, N.1
  • 29
    • 0036636107 scopus 로고    scopus 로고
    • The Wilms' tumor suppressor Wt1 is expressed in the coronary vasculature after myocardial infarction
    • Wagner, K. D. et al. The Wilms' tumor suppressor Wt1 is expressed in the coronary vasculature after myocardial infarction. FASEB J. 16, 1117-1119 (2002).
    • (2002) FASEB J. , vol.16 , pp. 1117-1119
    • Wagner, K.D.1
  • 30
    • 0016413580 scopus 로고
    • Biological behavior of malignant melanoma cells correlated to their survival in vivo
    • Fidler, I. J. Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res. 35, 218-224 (1975).
    • (1975) Cancer Res. , vol.35 , pp. 218-224
    • Fidler, I.J.1
  • 31
    • 33744958179 scopus 로고    scopus 로고
    • Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells
    • Yoo, M. H., Xu, X. M., Carlson, B. A., Gladyshev, V. N. & Hatfield, D. L. Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells. J. Biol. Chem. 281, 13005-13008 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 13005-13008
    • Yoo, M.H.1    Xu, X.M.2    Carlson, B.A.3    Gladyshev, V.N.4    Hatfield, D.L.5
  • 32
    • 0033587012 scopus 로고    scopus 로고
    • The Wilms' tumor gene product represses the transcription of thrombospondin 1 in response to overexpression of c-Jun
    • Dejong, V. et al. The Wilms' tumor gene product represses the transcription of thrombospondin 1 in response to overexpression of c-Jun. Oncogene 18, 3143-3151 (1999).
    • (1999) Oncogene , vol.18 , pp. 3143-3151
    • Dejong, V.1
  • 33
    • 83755162588 scopus 로고    scopus 로고
    • WT1 protein directly regulates expression of vascular endothelial growth factor and is a mediator of tumor response to hypoxia
    • McCarty, G., Awad, O. & Loeb, D. M. WT1 protein directly regulates expression of vascular endothelial growth factor and is a mediator of tumor response to hypoxia. J. Biol. Chem. 286, 43634-43643 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 43634-43643
    • McCarty, G.1    Awad, O.2    Loeb, D.M.3
  • 34
    • 0029071508 scopus 로고
    • Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing
    • Larsson, S. H. et al. Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing. Cell 81, 391-401 (1995).
    • (1995) Cell , vol.81 , pp. 391-401
    • Larsson, S.H.1
  • 35
    • 0032532734 scopus 로고    scopus 로고
    • WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes
    • Davies, R. C. et al. WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes. Genes Dev. 12, 3217-3225 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 3217-3225
    • Davies, R.C.1
  • 36
    • 0028208925 scopus 로고
    • Human umbilical vein endothelial cells display high-affinity c-kit receptors and produce a soluble form of the c-kit receptor
    • Broudy, V. C. et al. Human umbilical vein endothelial cells display high-affinity c-kit receptors and produce a soluble form of the c-kit receptor. Blood 83, 2145-2152 (1994).
    • (1994) Blood , vol.83 , pp. 2145-2152
    • Broudy, V.C.1
  • 38
    • 84868128328 scopus 로고    scopus 로고
    • Generation of functional blood vessels from a single c-kit\+ adult vascular endothelial stem cell
    • Fang, S., Wei, J., Pentinmikko, N., Leinonen, H. & Salven, P. Generation of functional blood vessels from a single c-kit\+ adult vascular endothelial stem cell. PLoS Biol. 10, e1001407 (2012).
    • (2012) PLoS Biol. , vol.10 , pp. e1001407
    • Fang, S.1    Wei, J.2    Pentinmikko, N.3    Leinonen, H.4    Salven, P.5
  • 39
    • 46449138664 scopus 로고    scopus 로고
    • Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart
    • Zhou, B. et al. Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature 454, 109-113 (2008).
    • (2008) Nature , vol.454 , pp. 109-113
    • Zhou, B.1
  • 40
    • 3042548695 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
    • Inai, T. et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am. J. Pathol. 165, 35-52 (2004).
    • (2004) Am. J. Pathol. , vol.165 , pp. 35-52
    • Inai, T.1
  • 41
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • Levy, A. P., Levy, N. S., Wegner, S. & Goldberg, M. A. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J. Biol. Chem. 270, 13333-13340 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 42
    • 0038265455 scopus 로고    scopus 로고
    • Oxygen-regulated expression of the Wilms' tumor suppressor Wt1 involves hypoxia-inducible factor-1 (HIF-1)
    • Wagner, K. D. et al. Oxygen-regulated expression of the Wilms' tumor suppressor Wt1 involves hypoxia-inducible factor-1 (HIF-1). FASEB J. 17, 1364-1366 (2003).
    • (2003) FASEB J. , vol.17 , pp. 1364-1366
    • Wagner, K.D.1
  • 43
    • 0037470245 scopus 로고    scopus 로고
    • Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)
    • Elvert, G. et al. Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1). J. Biol. Chem. 278, 7520-7530 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 7520-7530
    • Elvert, G.1
  • 44
    • 39249085138 scopus 로고    scopus 로고
    • Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice
    • Dimaio, T. A. et al. Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice. Dev. Biol. 315, 72-88 (2008).
    • (2008) Dev. Biol. , vol.315 , pp. 72-88
    • Dimaio, T.A.1
  • 45
    • 0030953387 scopus 로고    scopus 로고
    • Involvement of endothelial PECAM-1/CD31 in angiogenesis
    • DeLisser, H. M. et al. Involvement of endothelial PECAM-1/CD31 in angiogenesis. Am. J. Pathol. 151, 671-677 (1997).
    • (1997) Am. J. Pathol. , vol.151 , pp. 671-677
    • Delisser, H.M.1
  • 46
    • 2442631556 scopus 로고    scopus 로고
    • Stem cell factor/c-kit signaling promotes the survival, migration, and capillary tube formation of human umbilical vein endothelial cells
    • Matsui, J., Wakabayashi, T., Asada, M., Yoshimatsu, K. & Okada, M. Stem cell factor/c-kit signaling promotes the survival, migration, and capillary tube formation of human umbilical vein endothelial cells. J. Biol. Chem. 279, 18600-18607 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 18600-18607
    • Matsui, J.1    Wakabayashi, T.2    Asada, M.3    Yoshimatsu, K.4    Okada, M.5
  • 47
    • 34250719709 scopus 로고    scopus 로고
    • Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization
    • Nolan, D. J. et al. Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes Dev. 21, 1546-1558 (2007).
    • (2007) Genes Dev. , vol.21 , pp. 1546-1558
    • Nolan, D.J.1
  • 48
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: Functions of cells recruited to the tumor microenvironment
    • Hanahan, D. & Coussens, L. M. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21, 309-322 (2012).
    • (2012) Cancer Cell , vol.21 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 49
    • 84863991235 scopus 로고    scopus 로고
    • Myeloid suppressor cell depletion augments antitumor activity in lung cancer
    • Srivastava, M. K. et al. Myeloid suppressor cell depletion augments antitumor activity in lung cancer. PLoS ONE 7, e40677 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e40677
    • Srivastava, M.K.1
  • 50
    • 84901227839 scopus 로고    scopus 로고
    • WT1 regulates angiogenesis in Ewing Sarcoma
    • Katuri, V. et al. WT1 regulates angiogenesis in Ewing Sarcoma. Oncotarget 5, 2436-2449 (2014).
    • (2014) Oncotarget , vol.5 , pp. 2436-2449
    • Katuri, V.1
  • 51
    • 84884556145 scopus 로고    scopus 로고
    • History of myeloid-derived suppressor cells
    • Talmadge, J. E. & Gabrilovich, D. I. History of myeloid-derived suppressor cells. Nat. Rev. Cancer 13, 739-752 (2013).
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 739-752
    • Talmadge, J.E.1    Gabrilovich, D.I.2
  • 52
    • 84919708206 scopus 로고    scopus 로고
    • The telomeric protein TRF2 regulates angiogenesis by binding and activating the PDGFRb promoter
    • El Mai, M. et al. The telomeric protein TRF2 regulates angiogenesis by binding and activating the PDGFRb promoter. Cell Rep. 9, 1047-1060 (2014).
    • (2014) Cell Rep. , vol.9 , pp. 1047-1060
    • El Mai, M.1
  • 53
    • 84880332846 scopus 로고    scopus 로고
    • TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells
    • Biroccio, A. et al. TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells. Nat. Cell Biol. 15, 818-828 (2013).
    • (2013) Nat. Cell Biol. , vol.15 , pp. 818-828
    • Biroccio, A.1
  • 54
    • 23844474160 scopus 로고    scopus 로고
    • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
    • Song, E. et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat. Biotechnol. 23, 709-717 (2005).
    • (2005) Nat. Biotechnol. , vol.23 , pp. 709-717
    • Song, E.1
  • 55
    • 56449129810 scopus 로고    scopus 로고
    • Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
    • Lewis Phillips, G. D. et al. Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Res. 68, 9280-9290 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 9280-9290
    • Lewis Phillips, G.D.1
  • 56
    • 33646470202 scopus 로고    scopus 로고
    • An inducible mouse model for PAX2-dependent glomerular disease: Insights into a complex pathogenesis
    • Wagner, K. D. et al. An inducible mouse model for PAX2-dependent glomerular disease: insights into a complex pathogenesis. Curr. Biol. 16, 793-800 (2006).
    • (2006) Curr. Biol. , vol.16 , pp. 793-800
    • Wagner, K.D.1
  • 57
    • 84855264059 scopus 로고    scopus 로고
    • Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1
    • Chau, Y. Y. et al. Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1. PLoS Genet. 7, e1002404 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002404
    • Chau, Y.Y.1
  • 58
    • 0013939868 scopus 로고
    • Oestrous synchronization and pregnancy blocking in wild house mice (Mus musculus)
    • Chipman, R. K. & Fox, K. A. Oestrous synchronization and pregnancy blocking in wild house mice (Mus musculus). J. Reprod. Fertil. 12, 233-236 (1966).
    • (1966) J. Reprod. Fertil. , vol.12 , pp. 233-236
    • Chipman, R.K.1    Fox, K.A.2
  • 60
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia, G., Singer, O. & Verma, I. M. Production and purification of lentiviral vectors. Nat. Protoc. 1, 241-245 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 241-245
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 61
    • 34347218991 scopus 로고    scopus 로고
    • Vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • Liang, C. C., Park, A. Y. & Guan, J. L. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat. Protoc. 2, 329-333 (2007).
    • (2007) Nat. Protoc. , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 62
    • 65549083899 scopus 로고    scopus 로고
    • A critical analysis of current in vitro and in vivo angiogenesis assays
    • Staton, C. A., Reed, M. W. & Brown, N. J. A critical analysis of current in vitro and in vivo angiogenesis assays. Int. J. Exp. Pathol. 90, 195-221 (2009).
    • (2009) Int. J. Exp. Pathol. , vol.90 , pp. 195-221
    • Staton, C.A.1    Reed, M.W.2    Brown, N.J.3
  • 64
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • Bolte, S. & Cordelières, F. P. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224, 213-232 (2006).
    • (2006) J. Microsc. , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelières, F.P.2
  • 65
    • 0036190875 scopus 로고    scopus 로고
    • PROMO: Detection of known transcription regulatory elements using species-tailored searches
    • Messeguer, X. et al. PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 18, 333-334 (2002).
    • (2002) Bioinformatics , vol.18 , pp. 333-334
    • Messeguer, X.1
  • 66
    • 77958114729 scopus 로고    scopus 로고
    • GATA2 and Sp1 positively regulate the c-kit promoter in mast cells
    • Maeda, K., Nishiyama, C., Ogawa, H. & Okumura, K. GATA2 and Sp1 positively regulate the c-kit promoter in mast cells. J. Immunol. 185, 4252-4260 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 4252-4260
    • Maeda, K.1    Nishiyama, C.2    Ogawa, H.3    Okumura, K.4
  • 67
    • 79960011498 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor b/d (PPARb/d) is highly expressed in liposarcoma and promotes migration and proliferation
    • Wagner, K. D., Benchetrit, M., Bianchini, L., Michiels, J. F. & Wagner, N. Peroxisome proliferator-activated receptor b/d (PPARb/d) is highly expressed in liposarcoma and promotes migration and proliferation. J. Pathol. 224, 575-588 (2011).
    • (2011) J. Pathol. , vol.224 , pp. 575-588
    • Wagner, K.D.1    Benchetrit, M.2    Bianchini, L.3    Michiels, J.F.4    Wagner, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.