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Volumn 65, Issue 2, 2015, Pages 148-150

Stem cells versus senescence: The yin and yang of cardiac health

Author keywords

Aging; Biomarkers; Clinical trials; Heart failure; Ischemic heart disease; Regenerative medicine; Therapy

Indexed keywords

MOLECULAR MARKER; NUCLEOSTEMIN; PROTEIN KINASE PIM 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; NUCLEAR PROTEIN; NUCLEOSTEMIN PROTEIN, MOUSE;

EID: 84922616724     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.10.041     Document Type: Editorial
Times cited : (15)

References (20)
  • 1
    • 84893651437 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2014 update: A report from the american heart association
    • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics-2014 update: A report from the American Heart Association. Circulation 2014;129:e28-292.
    • (2014) Circulation , vol.129 , pp. e28-e292
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 3
    • 79959734150 scopus 로고    scopus 로고
    • Chronic diseases: The emerging pandemic
    • Terzic A, Waldman S. Chronic diseases: The emerging pandemic. Clin Transl Sci 2011;4:225-6.
    • (2011) Clin Transl Sci , vol.4 , pp. 225-226
    • Terzic, A.1    Waldman, S.2
  • 5
    • 84905739577 scopus 로고    scopus 로고
    • Translational strategies and challenges in regenerative medicine
    • Dimmeler S, Ding S, Rando TA, Trounson A. Translational strategies and challenges in regenerative medicine. Nat Med 2014;20:814-21.
    • (2014) Nat Med , vol.20 , pp. 814-821
    • Dimmeler, S.1    Ding, S.2    Rando, T.A.3    Trounson, A.4
  • 6
    • 84871717211 scopus 로고    scopus 로고
    • Increased expression of bubR1 protects against aneuploidy and cancer and extends healthy lifespan
    • Baker DJ, Dawlaty MM, Wijshake T, et al. Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. Nat Cell Biol 2013;15:96-102.
    • (2013) Nat Cell Biol , vol.15 , pp. 96-102
    • Baker, D.J.1    Dawlaty, M.M.2    Wijshake, T.3
  • 7
    • 80855138775 scopus 로고    scopus 로고
    • Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
    • Baker DJ, Wijshake T, Tchkonia T, et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 2011; 479:232-6.
    • (2011) Nature , vol.479 , pp. 232-236
    • Baker, D.J.1    Wijshake, T.2    Tchkonia, T.3
  • 8
    • 84901288438 scopus 로고    scopus 로고
    • The role of senescent cells in ageing
    • van Deursen JM. The role of senescent cells in ageing. Nature 2014;509:439-46.
    • (2014) Nature , vol.509 , pp. 439-446
    • Van Deursen, J.M.1
  • 9
    • 84871302192 scopus 로고    scopus 로고
    • Senescent cells: A novel therapeutic target for aging and age-related diseases
    • Naylor RM, Baker DJ, van Deursen JM. Senescent cells: A novel therapeutic target for aging and age-related diseases. Clin Pharmacol Ther 2013; 93:105-16.
    • (2013) Clin Pharmacol Ther , vol.93 , pp. 105-116
    • Naylor, R.M.1    Baker, D.J.2    Van Deursen, J.M.3
  • 10
    • 84874603171 scopus 로고    scopus 로고
    • Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities
    • Tchkonia T, Zhu Y, van Deursen J, Campisi J, Kirkland JL. Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities. J Clin Invest 2013;123:966-72.
    • (2013) J Clin Invest , vol.123 , pp. 966-972
    • Tchkonia, T.1    Zhu, Y.2    Van Deursen, J.3    Campisi, J.4    Kirkland, J.L.5
  • 11
    • 84922611540 scopus 로고    scopus 로고
    • Effect of aging on human mesenchymal stem cell therapy in ischemic cardiomyopathy patients
    • Golpanian S, El-Khorazaty J, Mendizabal A, et al. Effect of aging on human mesenchymal stem cell therapy in ischemic cardiomyopathy patients. J Am Coll Cardiol 2015;65:125-32.
    • (2015) J Am Coll Cardiol , vol.65 , pp. 125-132
    • Golpanian, S.1    El-Khorazaty, J.2    Mendizabal, A.3
  • 12
    • 84922600175 scopus 로고    scopus 로고
    • Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging
    • Hariharan N, Quijada P, Mohsin S, et al. Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging. J Am Coll Cardiol 2015;65:133-47.
    • (2015) J Am Coll Cardiol , vol.65 , pp. 133-147
    • Hariharan, N.1    Quijada, P.2    Mohsin, S.3
  • 13
    • 84917679165 scopus 로고    scopus 로고
    • A detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b and clonogenic capacity as biomarkers for clinical outcomes
    • for the Cardiovascular Cell Therapy Research Network (CCTRN)
    • Cogle CR, Wise E, Meacham AM, et al., for the Cardiovascular Cell Therapy Research Network (CCTRN). A detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b and clonogenic capacity as biomarkers for clinical outcomes. Circ Res 2014;115:867-74.
    • (2014) Circ Res , vol.115 , pp. 867-874
    • Cogle, C.R.1    Wise, E.2    Meacham, A.M.3
  • 14
    • 84922609188 scopus 로고    scopus 로고
    • Stem cell in the rough: Repair quotient mined out of a bone marrow niche
    • Behfar A, Terzic A. Stem cell in the rough: Repair quotient mined out of a bone marrow niche. Circ Res 2014;115:814-6.
    • (2014) Circ Res , vol.115 , pp. 814-816
    • Behfar, A.1    Terzic, A.2
  • 15
    • 84891705686 scopus 로고    scopus 로고
    • The advancing field of cell-based therapy: Insights and lessons from clinical trials
    • Telukuntla KS, Suncion VY, Schulman IH, Hare JM. The advancing field of cell-based therapy: Insights and lessons from clinical trials. J Am Heart Assoc 2013;2:e000338.
    • (2013) J Am Heart Assoc , vol.2 , pp. e000338
    • Telukuntla, K.S.1    Suncion, V.Y.2    Schulman, I.H.3    Hare, J.M.4
  • 17
    • 77955900387 scopus 로고    scopus 로고
    • Guided cardiopoiesis enhances therapeutic benefit of bone marrow human mesenchymal stem cells in chronic myocardial infarction
    • Behfar A, Yamada S, Crespo-Diaz R, et al. Guided cardiopoiesis enhances therapeutic benefit of bone marrow human mesenchymal stem cells in chronic myocardial infarction. J Am Coll Cardiol 2010;56:721-34.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 721-734
    • Behfar, A.1    Yamada, S.2    Crespo-Diaz, R.3
  • 18
    • 84878722569 scopus 로고    scopus 로고
    • Cardiopoietic stem cell therapy in heart failure: The C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics
    • Bartunek J, Behfar A, Dolatabadi D, et al. Cardiopoietic stem cell therapy in heart failure: The C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics. J Am Coll Cardiol 2013;61:2329-38.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 2329-2338
    • Bartunek, J.1    Behfar, A.2    Dolatabadi, D.3
  • 19
    • 84901036245 scopus 로고    scopus 로고
    • Regenerative heart failure therapy headed for optimization
    • Terzic A, Behfar A. Regenerative heart failure therapy headed for optimization. Eur Heart J 2014; 35:1231-4.
    • (2014) Eur Heart J , vol.35 , pp. 1231-1234
    • Terzic, A.1    Behfar, A.2
  • 20


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.