Chronic stress shifts the GABA reversal potential in the hippocampus and increases seizure susceptibility

Epilepsy Research

Volumn 109, Issue 1, 2015, Pages 13-27

  MacKenzie, Georgina ^a   Maguire, Jamie ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic stress; Epilepsy; GABA; KCC2

Indexed keywords

4 AMINOBUTYRIC ACID; BUMETANIDE; CORTICOSTERONE; GRAMICIDIN; KAINIC ACID; POTASSIUM CHLORIDE COTRANSPORTER 2; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; COTRANSPORTER; LOOP DIURETIC AGENT; POTASSIUM-CHLORIDE SYMPORTERS; SLC12A2 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CHRONIC STRESS; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPHOSPHORYLATION; DISEASE ASSOCIATION; GABAERGIC SYSTEM; HIPPOCAMPAL CA1 REGION; IMMOBILIZATION STRESS; MALE; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL PLASTICITY; NERVE EXCITABILITY; NONHUMAN; PROTEIN EXPRESSION; REGULATORY MECHANISM; SEIZURE SUSCEPTIBILITY; ACUTE DISEASE; ANIMAL; BLOOD; C57BL MOUSE; CHRONIC DISEASE; DISEASE MODEL; DRUG EFFECTS; EXERCISE; HIPPOCAMPUS; MEMBRANE POTENTIAL; MENTAL STRESS; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PYRAMIDAL NERVE CELL; SEIZURE;

ACUTE DISEASE; ANIMALS; BUMETANIDE; CHRONIC DISEASE; CORTICOSTERONE; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; KAINIC ACID; MALE; MEMBRANE POTENTIALS; MICE, INBRED C57BL; PHOSPHORYLATION; PYRAMIDAL CELLS; RESTRAINT, PHYSICAL; SEIZURES; SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS; SOLUTE CARRIER FAMILY 12, MEMBER 2; STRESS, PSYCHOLOGICAL; SYMPORTERS;

EID: 84922615013     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2014.10.003     Document Type: Article

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