Sub-cellular localisation studies may spuriously detect the yes-associated protein, YAP, in nucleoli leading to potentially invalid conclusions of its function

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Finch, Megan L ^a   Passman, Adam M ^a   Strauss, Robyn P ^a   Yeoh, George C ^a   Callus, Bernard A ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; FIBRILLARIN; FLUORESCENT DYE; HOECHST DYE; NUCLEAR PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; YES ASSOCIATED PROTEIN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP PROTEIN, MOUSE; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CARCINOGENESIS; CELL CULTURE; CELL GROWTH; CELL LABELING; CELL NUCLEUS; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; EMBRYO; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; LIVER; LIVER PRECURSOR CELL; MOUSE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STAINING; STEM CELL; WESTERN BLOTTING; ANIMAL; CELL LINE; GENETICS; METABOLISM; NUCLEOLUS; PHYSIOLOGY; PROTEIN TRANSPORT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CELL NUCLEOLUS; HUMANS; MICE; PHOSPHOPROTEINS; PROTEIN TRANSPORT;

EID: 84922613520     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114813     Document Type: Article

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