β-Hydroxy-β-methylbutyrate (HMB) normalizes dexamethasone-induced autophagy-lysosomal pathway in skeletal muscle

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Girón, María D ^a   Vílchez, Jose D ^a   Shreeram, Sathyavageeswaran ^b   Salto, Rafael ^a   Manzano, Manuel ^c   Cabrera, Elena ^a   Campos, Nefertiti ^c   Edens, Neile K ^d   Rueda, Ricardo ^c   López Pedrosa, Jose M ^c  

^a UNIVERSITY OF GRANADA   (Spain)

^b Abbott Nutrition R and D ^*  (Singapore)

^c ABBOTT LABORATORIES   (Spain)

^d ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROGIN 1; BETA HYDROXY BETA METHYLBUTYRATE; BUTYRIC ACID; CELL PROTEIN; DEXAMETHASONE; MUSCLE RING FINGER 1 PROTEIN; PROTEIN BNIP3; PROTEIN KINASE B; PROTEIN LC3 II; PROTEIN P62; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; BETA-HYDROXYISOVALERIC ACID; GLUCOCORTICOID; PROTEASOME; VALERIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GASTROCNEMIUS MUSCLE; IN VITRO STUDY; IN VIVO STUDY; LEAN BODY WEIGHT; LYSOSOME; MALE; MUSCLE ATROPHY; MUSCLE STRENGTH; MYOTUBE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSCRIPTION INITIATION; WEIGHT REDUCTION; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; MUSCULAR ATROPHY; PHOSPHORYLATION; SKELETAL MUSCLE CELL; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; AUTOPHAGY; DEXAMETHASONE; GLUCOCORTICOIDS; LYSOSOMES; MALE; MUSCLE FIBERS, SKELETAL; MUSCLE STRENGTH; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; VALERATES;

EID: 84922572431     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117520     Document Type: Article

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