-
1
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011; 147: 728-741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
3
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451: 1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
4
-
-
37649005234
-
Autophagy in the pathogenesis of Disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of Disease. Cell 2008; 132: 27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
5
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y. Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 2000; 150: 1507-1513.
-
(2000)
J Cell Biol
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
6
-
-
0035286734
-
Molecular dissection of autophagy: Two ubiquitin-like systems
-
Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2001; 2: 211-216.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 211-216
-
-
Ohsumi, Y.1
-
7
-
-
77953543377
-
The Beclin 1-VPS34 complex - At the crossroads of autophagy and beyond
-
Funderburk SF, Wang QJ, Yue Z. The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol 2010; 20: 355-362.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
8
-
-
0035809160
-
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
-
Kihara A, Noda T, Ishihara N, Ohsumi Y. Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 2001; 152: 519-530.
-
(2001)
J Cell Biol
, vol.152
, pp. 519-530
-
-
Kihara, A.1
Noda, T.2
Ishihara, N.3
Ohsumi, Y.4
-
9
-
-
33645078650
-
Regulation of membrane traffic by phosphoinositide 3-kinases
-
Lindmo K, Stenmark H. Regulation of membrane traffic by phosphoinositide 3-kinases. J Cell Sci 2006; 119: 605-614.
-
(2006)
J Cell Sci
, vol.119
, pp. 605-614
-
-
Lindmo, K.1
Stenmark, H.2
-
10
-
-
0029148577
-
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
-
Brown WJ, DeWald DB, Emr SD, Plutner H, Balch WE. Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol 1995; 130: 781-796.
-
(1995)
J Cell Biol
, vol.130
, pp. 781-796
-
-
Brown, W.J.1
DeWald, D.B.2
Emr, S.D.3
Plutner, H.4
Balch, W.E.5
-
11
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
Schu PV, Takegawa K, Fry MJ, Stack JH, Waterfield MD, Emr SD. Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 1993; 260: 88-91.
-
(1993)
Science
, vol.260
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
12
-
-
0027256130
-
A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole
-
Stack JH, Herman PK, Schu PV, Emr SD. A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J 1993; 12: 2195-2204.
-
(1993)
EMBO J
, vol.12
, pp. 2195-2204
-
-
Stack, J.H.1
Herman, P.K.2
Schu, P.V.3
Emr, S.D.4
-
13
-
-
44149127993
-
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
-
Juhász G, Hill JH, Yan Y, Sass M, Baehrecke EH, Backer JM et al. The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. J Cell Biol 2008; 181: 2347-2360.
-
(2008)
J Cell Biol
, vol.181
, pp. 2347-2360
-
-
Juhász, G.1
Hill, J.H.2
Yan, Y.3
Sass, M.4
Baehrecke, E.H.5
Backer, J.M.6
-
14
-
-
43949092111
-
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
-
Lindmo K, Brech A, Finley KD, Gaumer S, Contamine D, Rusten TE et al. The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates. Autophagy 2008; 4: 500-506.
-
(2008)
Autophagy
, vol.4
, pp. 500-506
-
-
Lindmo, K.1
Brech, A.2
Finley, K.D.3
Gaumer, S.4
Contamine, D.5
Rusten, T.E.6
-
15
-
-
0036387157
-
Steroid regulation of midgut cell death during Drosophila development
-
Lee C-Y, Cooksey BAK, Baehrecke EH. Steroid regulation of midgut cell death during Drosophila development. Dev Biol 2002; 250: 101-111.
-
(2002)
Dev Biol
, vol.250
, pp. 101-111
-
-
Lee, C.-Y.1
Cooksey, B.A.K.2
Baehrecke, E.H.3
-
16
-
-
0035040496
-
Steroid regulation of autophagic programmed cell death during development
-
Lee C-Y, Baehrecke EH. Steroid regulation of autophagic programmed cell death during development. Development 2001; 128: 1443-1455.
-
(2001)
Development
, vol.128
, pp. 1443-1455
-
-
Lee, C.-Y.1
Baehrecke, E.H.2
-
17
-
-
4344608793
-
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
-
Rusten TE, Lindmo K, Juhasz G, Sass M, Seglen PO, Brech A et al. Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway. Dev Cell 2004; 7: 179-192.
-
(2004)
Dev Cell
, vol.7
, pp. 179-192
-
-
Rusten, T.E.1
Lindmo, K.2
Juhasz, G.3
Sass, M.4
Seglen, P.O.5
Brech, A.6
-
18
-
-
4344563878
-
Role and regulation of starvation-induced autophagy in the Drosophila fat body
-
Scott RC, Schuldiner O, Neufeld TP. Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev Cell 2004; 7: 167-178.
-
(2004)
Dev Cell
, vol.7
, pp. 167-178
-
-
Scott, R.C.1
Schuldiner, O.2
Neufeld, T.P.3
-
19
-
-
0033538439
-
Nitric oxide contributes to behavioral, cellular, and developmental responses to low oxygen in Drosophila
-
Wingrove JA, O'Farrell PH. Nitric oxide contributes to behavioral, cellular, and developmental responses to low oxygen in Drosophila. Cell 1999; 98: 105-114.
-
(1999)
Cell
, vol.98
, pp. 105-114
-
-
Wingrove, J.A.1
O'Farrell, P.H.2
-
20
-
-
66149179367
-
Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity
-
Wilkinson S, O'Prey J, Fricker M, Ryan KM. Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity. Genes Dev 2009; 23: 1283-1288.
-
(2009)
Genes Dev
, vol.23
, pp. 1283-1288
-
-
Wilkinson, S.1
O'Prey, J.2
Fricker, M.3
Ryan, K.M.4
-
21
-
-
70350571244
-
Autophagy, not apoptosis, is essential for midgut cell death in Drosophila
-
Denton D, Shravage B, Simin R, Mills K, Berry DL, Baehrecke EH et al. Autophagy, not apoptosis, is essential for midgut cell death in Drosophila. Curr Biol 2009; 19: 1741-1746.
-
(2009)
Curr Biol
, vol.19
, pp. 1741-1746
-
-
Denton, D.1
Shravage, B.2
Simin, R.3
Mills, K.4
Berry, D.L.5
Baehrecke, E.H.6
-
22
-
-
68349110789
-
JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy
-
Wu H, Wang MC, Bohmann D. JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy. Mech Dev 2009; 126: 624-637.
-
(2009)
Mech Dev
, vol.126
, pp. 624-637
-
-
Wu, H.1
Wang, M.C.2
Bohmann, D.3
-
23
-
-
36849088609
-
Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila
-
Berry DL, Baehrecke EH. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell 2007; 131: 1137-1148.
-
(2007)
Cell
, vol.131
, pp. 1137-1148
-
-
Berry, D.L.1
Baehrecke, E.H.2
-
24
-
-
77955903343
-
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
-
Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjørkøy G, Johansen T et al. Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. J Cell Biol 2010; 190: 523-531.
-
(2010)
J Cell Biol
, vol.190
, pp. 523-531
-
-
Nezis, I.P.1
Shravage, B.V.2
Sagona, A.P.3
Lamark, T.4
Bjørkøy, G.5
Johansen, T.6
-
25
-
-
52249085861
-
Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis
-
Hou YC, Chittaranjan S, Barbosa SG, McCall K, Gorski SM. Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis. J Cell Biol 2008; 182: 1127-1139.
-
(2008)
J Cell Biol
, vol.182
, pp. 1127-1139
-
-
Hou, Y.C.1
Chittaranjan, S.2
Barbosa, S.G.3
McCall, K.4
Gorski, S.M.5
-
26
-
-
84883740868
-
Uba1 functions in Atg7- and Atg3-independent autophagy
-
Chang T-K, Shravage BV, Hayes SD, Powers CM, Simin RT, Harper JW et al. Uba1 functions in Atg7- and Atg3-independent autophagy. Nat Cell Biol 2013; 15 : 1067-1078.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1067-1078
-
-
Chang, T.-K.1
Shravage, B.V.2
Hayes, S.D.3
Powers, C.M.4
Simin, R.T.5
Harper, J.W.6
-
27
-
-
84864295258
-
Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation
-
Deretic V, Jiang S, Dupont N. Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation. Trends Cell Biol 2012; 22: 397-406.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 397-406
-
-
Deretic, V.1
Jiang, S.2
Dupont, N.3
-
28
-
-
84874531109
-
Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila
-
Shravage BV, Hill JH, Powers CM, Wu L, Baehrecke EH. Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila. Development 2013; 140 : 1321-1329.
-
(2013)
Development
, vol.140
, pp. 1321-1329
-
-
Shravage, B.V.1
Hill, J.H.2
Powers, C.M.3
Wu, L.4
Baehrecke, E.H.5
-
29
-
-
84878691312
-
Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease
-
Nemazanyy I, Blaauw B, Paolini C, Caillaud C, Protasi F, Mueller A et al. Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease. EMBO Mol Med 2013; 5: 870-890.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 870-890
-
-
Nemazanyy, I.1
Blaauw, B.2
Paolini, C.3
Caillaud, C.4
Protasi, F.5
Mueller, A.6
-
30
-
-
0023739386
-
Protein sorting in Saccharomyces cerevisiae: Isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases
-
Robinson JS, Klionsky DJ, Banta LM, Emr SD. Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 1988; 8: 4936-4948.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 4936-4948
-
-
Robinson, J.S.1
Klionsky, D.J.2
Banta, L.M.3
Emr, S.D.4
-
31
-
-
84863116629
-
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
-
Jaber N, Dou Z, Chen JS, Catanzaro J, Jiang YP, Ballou LM et al. Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proc Natl Acad Sci USA 2012; 109: 2003-2008.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2003-2008
-
-
Jaber, N.1
Dou, Z.2
Chen, J.S.3
Catanzaro, J.4
Jiang, Y.P.5
Ballou, L.M.6
-
32
-
-
77952722628
-
Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway
-
Zhou X, Wang L, Hasegawa H, Amin P, Han BX, Kaneko S et al. Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway. Proc Natl Acad Sci USA 2010; 107: 9424-9429.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9424-9429
-
-
Zhou, X.1
Wang, L.2
Hasegawa, H.3
Amin, P.4
Han, B.X.5
Kaneko, S.6
-
33
-
-
77953948764
-
Activation of autophagy during cell death requires the engulfment receptor Draper
-
McPhee CK, Logan MA, Freeman MR, Baehrecke EH. Activation of autophagy during cell death requires the engulfment receptor Draper. Nature 2010; 465: 1093-1096.
-
(2010)
Nature
, vol.465
, pp. 1093-1096
-
-
McPhee, C.K.1
Logan, M.A.2
Freeman, M.R.3
Baehrecke, E.H.4
-
34
-
-
70349687405
-
Discovery of Atg5/Atg7-independent alternative macroautophagy
-
Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T et al. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature 2009; 461: 654-658.
-
(2009)
Nature
, vol.461
, pp. 654-658
-
-
Nishida, Y.1
Arakawa, S.2
Fujitani, K.3
Yamaguchi, H.4
Mizuta, T.5
Kanaseki, T.6
-
35
-
-
84863728064
-
Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila
-
Denton D, Chang TK, Nicolson S, Shravage B, Simin R, Baehrecke EH et al. Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila. Cell Death Differ 2012; 19: 1299-1307.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1299-1307
-
-
Denton, D.1
Chang, T.K.2
Nicolson, S.3
Shravage, B.4
Simin, R.5
Baehrecke, E.H.6
-
36
-
-
0034282751
-
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
-
Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM et al. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J 2000; 19: 4577-4588.
-
(2000)
EMBO J
, vol.19
, pp. 4577-4588
-
-
Gillooly, D.J.1
Morrow, I.C.2
Lindsay, M.3
Gould, R.4
Bryant, N.J.5
Gaullier, J.M.6
-
37
-
-
0035032723
-
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
-
Kihara A, Kabeya Y, Ohsumi Y, Yoshimori T. Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep 2001; 2: 330-335.
-
(2001)
EMBO Rep
, vol.2
, pp. 330-335
-
-
Kihara, A.1
Kabeya, Y.2
Ohsumi, Y.3
Yoshimori, T.4
-
38
-
-
33749392341
-
The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process
-
Muro I, Berry DL, Huh JR, Chen CH, Huang H, Yoo SJ et al. The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. Development 2006; 133: 3305-3315.
-
(2006)
Development
, vol.133
, pp. 3305-3315
-
-
Muro, I.1
Berry, D.L.2
Huh, J.R.3
Chen, C.H.4
Huang, H.5
Yoo, S.J.6
|