Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 5, 2015, Pages 519-526

  Wünsche, Christin ^a   Koch, Alexander ^a   Goldschmeding, Roel ^b   Schwalm, Stephanie ^a   Meyer Zu Heringdorf, Dagmar ^a   Huwiler, Andrea ^c   Pfeilschifter, Josef ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Connective tissue growth factor; Human mesangial cell; Kidney; S1P receptor; Sphingosine 1 phosphate; Transforming growth factor 2

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; SMAD PROTEIN; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 5; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; CTGF PROTEIN, HUMAN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; PROTEIN KINASE INHIBITOR; SMAD4 PROTEIN; SMAD4 PROTEIN, MOUSE;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; MESANGIUM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; RNA INTERFERENCE; TIME;

CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; MESANGIAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; RECEPTORS, LYSOSPHINGOLIPID; RNA INTERFERENCE; RNA, MESSENGER; SMAD4 PROTEIN; TIME FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA2; UP-REGULATION;

EID: 84922496662     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2015.01.003     Document Type: Article

References (40)

1. A. Leask, and D.J. Abraham TGF-beta signaling and the fibrotic response FASEB J. 18 2004 816 827
2. Y. Chen, I.E. Blom, S. Sa, R. Goldschmeding, D.J. Abraham, and A. Leask CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC Kidney Int. 62 2002 1149 1159
3. P. Bork The modular architecture of a new family of growth regulators related to connective tissue growth factor FEBS Lett. 327 1993 125 130
4. B.L. Riser, P. Cortes, M. DeNichilo, P.V. Deshmukh, P.S. Chahal, A.K. Mohammed, J. Yee, and D. Kahkonen Urinary CCN2 (CTGF) as a possible predictor of diabetic nephropathy: preliminary report Kidney Int. 64 2003 451 458
5. J.K. Crean, F. Furlong, D. Finlay, D. Mitchell, M. Murphy, B. Conway, H.R. Brady, C. Godson, and F. Martin Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization FASEB J. 18 2004 1541 1543
6. A. Koch, J. Pfeilschifter, and A. Huwiler Sphingosine 1-phosphate in renal diseases Cell. Physiol. Biochem. 31 2013 745 760
7. S. Schwalm, J. Pfeilschifter, and A. Huwiler Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases Biochim. Biophys. Acta 1831 2013 239 250
8. G.M. Strub, M. Maceyka, N.C. Hait, S. Milstien, and S. Spiegel Extracellular and intracellular actions of sphingosine-1-phosphate Adv. Exp. Med. Biol. 688 2010 141 155
9. V. Brinkmann Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology Pharmacol. Ther. 115 2007 84 105
10. S. Ren, A. Babelova, K. Moreth, C. Xin, W. Eberhardt, A. Doller, H. Pavenstädt, L. Schaefer, J. Pfeilschifter, and A. Huwiler Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression Kidney Int. 76 2009 857 867
11. C. Xin, S. Ren, B. Kleuser, S. Shabahang, W. Eberhardt, H. Radeke, M. Schäfer-Korting, J. Pfeilschifter, and A. Huwiler Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-β-induced cell responses J. Biol. Chem. 279 2004 35255 35262
12. A. Francki, P. Uciechowski, J. Floege, J. von der Ohe, K. Resch, and H.H. Radeke Autocrine growth regulation of human glomerular mesangial cells is primarily mediated by basic fibroblast growth factor Am. J. Pathol. 147 1995 1372 1382
13. A. Koch, A. Völzke, C. Wünsche, D. Meyer zu Heringdorf, A. Huwiler, and J. Pfeilschifter Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells Br. J. Pharmacol. 166 2012 1018 1032
14. A. Huwiler, S. Stabel, D. Fabbro, and J. Pfeilschifter Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells comparison of hypertrophic and hyperplastic agonists Biochem. J. 305 1995 777 784
15. F. Döll, J. Pfeilschifter, and A. Huwiler The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7 Biochim. Biophys. Acta 1738 2005 72 81
16. T.Q. Nguyen, L. Tarnow, A. Jorsal, N. Oliver, P. Roestenberg, Y. Ito, H.H. Parving, P. Rossing, F.A. van Nieuwenhoven, and R. Goldschmeding Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy Diabetes Care 31 2008 1177 1182
17. A. Völzke, A. Koch, D. Meyer Zu Heringdorf, A. Huwiler, and J. Pfeilschifter Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells Biochim. Biophys. Acta 1841 2014 11 21
18. A. Huwiler, and J. Pfeilschifter Transforming growth factor beta 2 stimulates acute and chronic activation of the mitogen-activated protein kinase cascade in rat renal mesangial cells FEBS Lett. 354 1994 255 258
19. T. Hayashida, A.C. Poncelet, S.C. Hubchak, and H.W. Schnaper TGF-beta1 activates MAP kinase in human mesangial cells: a possible role in collagen expression Kidney Int. 56 1999 1710 1720
20. M.J. Lee, M. Evans, and T. Hla The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway J. Biol. Chem. 271 1996 11272 11279
21. R. van Doorn, M.A. Lopes Pinheiro, G. Kooij, K. Lakeman, B. van het Hof, S.M. van der Pol, D. Geerts, J. van Horssen, P. van der Valk, E. van der Kam, E. Ronken, A. Reijerkerk, and H.E. Vries Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier J. Neuroinflammation 9 2012 133
22. C.N. Jenne, A. Enders, R. Rivera, S.R. Watson, A.J. Bankovich, J.P. Pereira, Y. Xu, C.M. Roots, J.N. Beilke, A. Banerjee, S.L. Reiner, S.A. Miller, A.S. Weinmann, C.C. Goodnow, L.L. Lanier, J.G. Cyster, and J. Chun T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow J. Exp. Med. 206 2009 2469 2481
23. T. Walzer, L. Chiossone, J. Chaix, A. Calver, C. Carozzo, L. Garrigue-Antar, Y. Jacques, M. Baratin, E. Tomasello, and E. Vivier Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor Nat. Immunol. 8 2007 1337 1344
24. W.M. Hu, L. Li, B.Q. Jing, Y.S. Zhao, C.L. Wang, L. Feng, and Y.E. Xie Effect of S1P5 on proliferation and migration of human esophageal cancer cells World J. Gastroenterol. 16 2010 1859 1866
25. A.S. Novgorodov, M. El-Alwani, J. Bielawski, L.M. Obeid, and T.I. Gudz Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration FASEB J. 21 2007 1503 1514
26. C.G. Jung, H.J. Kim, V.E. Miron, S. Cook, T.E. Kennedy, C.A. Foster, J.P. Antel, and B. Soliven Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells Glia 55 2007 1656 1667
27. J. Igarashi, M. Miyoshi, T. Hashimoto, Y. Kubota, and H. Kosaka Hydrogen peroxide induces S1P1 receptors and sentitizes vascular endothelial cells to sphingosine 1-phosphate, a platelet-derived lipid mediator Am. J. Physiol. Cell Physiol. 292 2007 C740 C748
28. A. Bai, H. Hu, M. Yeung, and J. Chen Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription J. Immunol. 178 2007 7632 7639
29. i increases in renal mesangial cell Biochim. Biophys. Acta 1831 2013 1634 1643
30. F. Cencetti, C. Bernacchioni, P. Nincheri, C. Donati, and P. Bruni Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis Mol. Biol. Cell 21 2010 1111 1124
31. F. Cencetti, C. Bernacchioni, F. Tonelli, E. Roberts, C. Donati, and P. Bruni TGFβ1 evokes myoblast apoptotic response via a novel signaling pathway involving S1P4 transactivation upstream of Rho-kinase-2 activation FASEB J. 27 2013 4532 4546
32. J.F. Santibañez, M. Quintanilla, and C. Bernabeu TGF-β/TGF-β receptor system and its role in physiological and pathological conditions Clin. Sci. (Lond.) 121 2011 233 251
33. Y. Kono, T. Nishiuma, Y. Nishimura, Y. Kotani, T. Okada, S. Nakamura, and M. Yokoyama Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta1 Am. J. Respir. Cell Mol. Biol. 37 2007 395 404
34. S. Katsuma, Y. Ruike, T. Yano, M. Kimura, A. Hirasawa, and G. Tsujimoto Transcriptional regulation of connective tissue growth factor by sphingosine 1-phosphate in rat cultured mesangial cells FEBS Lett. 579 2005 2576 2582
35. B. Sauer, R. Vogler, H. von Wenckstern, M. Fujii, M.B. Anzano, A.B. Glick, M. Schäfer-Korting, A.B. Roberts, and B. Kleuser Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes J. Biol. Chem. 279 2004 38471 38479
36. C.D. Keller, P. Rivera Gil, M. Tölle, M. van der Giet, J. Chun, H.H. Radeke, M. Schäfer-Korting, and B. Kleuser Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling Am. J. Pathol. 170 2007 281 292
37. V. Brinkmann, M.D. Davies, C.E. Heise, R. Albert, S. Cottens, R. Hof, C. Bruns, E. Prieschl, T. Baumruker, P. Hiestand, C.A. Foster, M. Zollinger, and K.R. Lynch The immune modulator FTY720 targets sphingosine 1-phosphate receptors J. Biol. Chem. 277 2002 21453 21457
38. C. Xin, S. Ren, W. Eberhardt, J. Pfeilschifter, and A. Huwiler The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells Br. J. Pharmacol. 147 2006 164 174
39. D.A. Lebman, and S. Spiegel Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling J. Lipid Res. 49 2008 1388 1394
40. N. Ancellin, and T. Hla Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5 J. Biol. Chem. 274 1999 18997 19002