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Volumn 17, Issue 1, 2014, Pages 32-37

Effect of ranolazine on atrial fibrillation in patients with non-ST elevation acute coronary syndromes: Observations from the MERLIN-TIMI 36 trial

Author keywords

Acute coronary syndromes; Anti arrhythmic therapy; Atrial fibrillation; Ranolazine

Indexed keywords

PLACEBO; RANOLAZINE; ACETANILIDE DERIVATIVE; PIPERAZINE DERIVATIVE; SODIUM CHANNEL BLOCKING AGENT;

EID: 84922443836     PISSN: 10995129     EISSN: 15322092     Source Type: Journal    
DOI: 10.1093/europace/euu217     Document Type: Article
Times cited : (45)

References (27)
  • 1
    • 84866732231 scopus 로고    scopus 로고
    • ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
    • Steg PG, James SK, Atar D, Badano LP, Blomstrom-Lundqvist C, Borger MA, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2012;33:2569-619
    • (2012) Eur Heart J , vol.33 , pp. 2569-2619
    • Steg, P.G.1    James, S.K.2    Atar, D.3    Badano, L.P.4    Blomstrom-Lundqvist, C.5    Borger, M.A.6
  • 2
    • 68949140953 scopus 로고    scopus 로고
    • Antithrombotic therapy and outcomes of patients with atrial fibrillation following primary percutaneous coronary intervention: Results from the apex-ami trial
    • Lopes RD, Elliott LE, White HD, Hochman JS, Van De Werf F, Ardissino D, et al. Antithrombotic therapy and outcomes of patients with atrial fibrillation following primary percutaneous coronary intervention: results from the APEX-AMI trial. Eur Heart J 2009;30:2019-28
    • (2009) Eur Heart J , vol.30 , pp. 2019-2028
    • Lopes, R.D.1    Elliott, L.E.2    White, H.D.3    Hochman, J.S.4    Van De Werf, F.5    Ardissino, D.6
  • 3
    • 46249109867 scopus 로고    scopus 로고
    • Shortand long-term outcomes following atrial fibrillation in patients with acute coronary syndromes with or without ST-segment elevation
    • Lopes RD, Pieper KS, Horton JR, Al-Khatib SM, Newby LK, Mehta RH, et al. Shortand long-term outcomes following atrial fibrillation in patients with acute coronary syndromes with or without ST-segment elevation. Heart 2008;94:867-73
    • (2008) Heart , vol.94 , pp. 867-873
    • Lopes, R.D.1    Pieper, K.S.2    Horton, J.R.3    Al-Khatib, S.M.4    Newby, L.K.5    Mehta, R.H.6
  • 4
    • 79957509557 scopus 로고    scopus 로고
    • Atrial fibrillation and death after myocardial infarction: A community study
    • Jabre P, Jouven X, Adnet F, Thabut G, Bielinski SJ,Weston SA, et al. Atrial fibrillation and death after myocardial infarction: a community study. Circulation 2011;123: 2094-100
    • (2011) Circulation , vol.123 , pp. 2094-2100
    • Jabre, P.1    Jouven, X.2    Adnet, F.3    Thabut, G.4    Bielinski, S.J.5    Weston, S.A.6
  • 5
    • 33745368556 scopus 로고    scopus 로고
    • Inhibition of the late sodium current as a potential cardioprotective principle: Effects of the late sodiumcurrent inhibitor ranolazine
    • Belardinelli L, Shryock JC, Fraser H. Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodiumcurrent inhibitor ranolazine. Heart 2006;92:iv6-iv14
    • (2006) Heart , vol.92 , pp. iv6-iv14
    • Belardinelli, L.1    Shryock, J.C.2    Fraser, H.3
  • 6
    • 33744455453 scopus 로고    scopus 로고
    • Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions
    • Chaitman BR. Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions. Circulation 2006;113:2462-72
    • (2006) Circulation , vol.113 , pp. 2462-2472
    • Chaitman, B.R.1
  • 8
    • 84873057304 scopus 로고    scopus 로고
    • Role of late sodium channel current block in the management of atrial fibrillation
    • Burashnikov A, Antzelevitch C. Role of Late Sodium Channel Current Block in the Management of Atrial Fibrillation. Cardiovasc Drugs Ther 2013;27:79-89
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 79-89
    • Burashnikov, A.1    Antzelevitch, C.2
  • 9
    • 34748873780 scopus 로고    scopus 로고
    • Atriumselective sodium channel block as a strategy for suppression of atrial fibrillation: Differences in sodium channel inactivation between atria and ventricles and the role of ranolazine
    • Burashnikov A, Di Diego JM, Zygmunt AC, Belardinelli L, Antzelevitch C. Atriumselective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine. Circulation 2007;116:1449-57
    • (2007) Circulation , vol.116 , pp. 1449-1457
    • Burashnikov, A.1    Di Diego, J.M.2    Zygmunt, A.C.3    Belardinelli, L.4    Antzelevitch, C.5
  • 10
    • 33745000050 scopus 로고    scopus 로고
    • Evaluation of a novel anti-ischemic agent in acute coronary syndromes: Design and rationale for the metabolic efficiency with ranolazine for less ischemia in non-st-elevation acute coronary syndromes (merlin)-timi 36 trial
    • e1-9
    • Morrow DA, Scirica BM, Karwatowska-Prokopczuk E, Skene A, McCabe CH, Braunwald E. Evaluation of a novel anti-ischemic agent in acute coronary syndromes: design and rationale for the metabolic efficiency with ranolazine for less ischemia in non-ST-elevation acute coronary syndromes (MERLIN)-TIMI 36 trial. Am Heart J 2006;151:1186 e1-9
    • (2006) Am Heart J , vol.151 , pp. 1186
    • Morrow, D.A.1    Scirica, B.M.2    Karwatowska-Prokopczuk, E.3    Skene, A.4    McCabe, C.H.5    Braunwald, E.6
  • 11
    • 35148850168 scopus 로고    scopus 로고
    • Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non st-segment elevation acute coronary syndrome: Results from the metabolic efficiency with ranolazine for less ischemia in non-st-elevation acute coronary syndrome thrombolysis in myocardial infarction 36 (merlin-timi 36) randomized controlled trial
    • Scirica BM, Morrow DA, Hod H, Murphy SA, Belardinelli L, Hedgepeth CM, et al. Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the metabolic efficiency with ranolazine for less ischemia in non-ST-elevation acute coronary syndrome thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) randomized controlled trial. Circulation 2007;116: 1647-52
    • (2007) Circulation , vol.116 , pp. 1647-1652
    • Scirica, B.M.1    Morrow, D.A.2    Hod, H.3    Murphy, S.A.4    Belardinelli, L.5    Hedgepeth, C.M.6
  • 12
    • 34247526904 scopus 로고    scopus 로고
    • Effects of ranolazine on recurrent cardiovascular events in patients with non-st-elevation acute coronary syndromes: The merlin-timi 36 randomized trial
    • Morrow DA, Scirica BM, Karwatowska-Prokopczuk E, Murphy SA, Budaj A, Varshavsky S, et al. Effects of ranolazine on recurrent cardiovascular events in patients with non-ST-elevation acute coronary syndromes: the MERLIN-TIMI 36 Randomized Trial. JAMA 2007;297:1775-83
    • (2007) Jama , vol.297 , pp. 1775-1783
    • Morrow, D.A.1    Scirica, B.M.2    Karwatowska-Prokopczuk, E.3    Murphy, S.A.4    Budaj, A.5    Varshavsky, S.6
  • 13
    • 34249294835 scopus 로고    scopus 로고
    • Preventing tomorrow's sudden cardiac death today: Part I: Current data on risk stratification for sudden cardiac death
    • Al-Khatib SM, Sanders GD, Bigger JT, Buxton AE, Califf RM, Carlson M, et al. Preventing tomorrow's sudden cardiac death today: part I: current data on risk stratification for sudden cardiac death. Am Heart J 2007;153:941-50
    • (2007) Am Heart J , vol.153 , pp. 941-950
    • Al-Khatib, S.M.1    Sanders, G.D.2    Bigger, J.T.3    Buxton, A.E.4    Califf, R.M.5    Carlson, M.6
  • 14
    • 44949176560 scopus 로고    scopus 로고
    • Belardinelli L.Anincrease of late sodiumcurrent induces delayed after depolarizations and sustained triggered activity in atrial myocytes
    • SongY, Shryock JC, Belardinelli L.Anincrease of late sodiumcurrent induces delayed after depolarizations and sustained triggered activity in atrial myocytes. Am J Physiol Heart Circ Physiol 2008;294:H2031-9
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , pp. H2031-H2039
    • Songy Shryock, J.C.1
  • 17
    • 84874404797 scopus 로고    scopus 로고
    • Mechanisms of ranolazine's dual protection against atrial and ventricular fibrillation
    • Verrier RL, Kumar K, Nieminen T, Belardinelli L. Mechanisms of ranolazine's dual protection against atrial and ventricular fibrillation. Europace 2013;15:317-24
    • (2013) Europace , vol.15 , pp. 317-324
    • Verrier, R.L.1    Kumar, K.2    Nieminen, T.3    Belardinelli, L.4
  • 18
    • 64049099187 scopus 로고    scopus 로고
    • Ischemia detected on continuous electrocardiography after acute coronary syndrome: Observations from the merlin-timi 36 (metabolic efficiency with ranolazine for less ischemia in non-st-elevation acute coronary syndrome-thrombolysis in myocardial infarction 36) trial
    • Scirica BM, Morrow DA, Budaj A, Dalby AJ, Mohanavelu S, Qin J, et al. Ischemia detected on continuous electrocardiography after acute coronary syndrome: observations from the MERLIN-TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-Thrombolysis In Myocardial Infarction 36) trial. J Am Coll Cardiol 2009;53:1411-21
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1411-1421
    • Scirica, B.M.1    Morrow, D.A.2    Budaj, A.3    Dalby, A.J.4    Mohanavelu, S.5    Qin, J.6
  • 19
    • 67649795769 scopus 로고    scopus 로고
    • Ranolazine exerts potent effects on atrial electrical properties and abbreviates atrial fibrillation duration in the intact porcine heart
    • Kumar K, Nearing BD, CarvasM, Nascimento BC, Acar M, Belardinelli L, et al. Ranolazine exerts potent effects on atrial electrical properties and abbreviates atrial fibrillation duration in the intact porcine heart. J Cardiovasc Electrophysiol 2009;20: 796-802
    • (2009) J Cardiovasc Electrophysiol , vol.20 , pp. 796-802
    • Kumar, K.1    Nearing, B.D.2    Carvasm Nascimento, B.C.3    Acar, M.4    Belardinelli, L.5
  • 20
    • 80051802104 scopus 로고    scopus 로고
    • Comparison of effectiveness and safety of ranolazine versus amiodarone for preventing atrial fibrillation after coronary artery bypass grafting
    • Miles RH, Passman R, Murdock DK. Comparison of effectiveness and safety of ranolazine versus amiodarone for preventing atrial fibrillation after coronary artery bypass grafting. Am J Cardiol 2011;108:673-6
    • (2011) Am J Cardiol , vol.108 , pp. 673-676
    • Miles, R.H.1    Passman, R.2    Murdock, D.K.3
  • 21
    • 84864953997 scopus 로고    scopus 로고
    • Comparison of effectiveness of ranolazine plus amiodarone versus amiodarone alone for conversion of recent-onset atrial fibrillation
    • Fragakis N, Koskinas KC, Katritsis DG, Pagourelias ED, Zografos T, Geleris P. Comparison of effectiveness of ranolazine plus amiodarone versus amiodarone alone for conversion of recent-onset atrial fibrillation. Am J Cardiol 2012;110:673-7
    • (2012) Am J Cardiol , vol.110 , pp. 673-677
    • Fragakis, N.1    Koskinas, K.C.2    Katritsis, D.G.3    Pagourelias, E.D.4    Zografos, T.5    Geleris, P.6
  • 22
    • 84896466536 scopus 로고    scopus 로고
    • Ranolazine enhances the efficacy of amiodarone for conversion of recent-onset atrial fibrillation
    • Koskinas KC, Fragakis N, Katritsis D, Skeberis V, Vassilikos V. Ranolazine enhances the efficacy of amiodarone for conversion of recent-onset atrial fibrillation. Europace 2014;16:973-9
    • (2014) Europace , vol.16 , pp. 973-979
    • Koskinas, K.C.1    Fragakis, N.2    Katritsis, D.3    Skeberis, V.4    Vassilikos, V.5
  • 23
    • 84857995406 scopus 로고    scopus 로고
    • The use of ranolazine to facilitate electrical cardioversion in cardioversion-resistant patients: A case series
    • Murdock DK, Kaliebe J, Larrain G. The use of ranolazine to facilitate electrical cardioversion in cardioversion-resistant patients: a case series. Pacing Clin Electrophysiol 2012;35:302-7
    • (2012) Pacing Clin Electrophysiol , vol.35 , pp. 302-307
    • Murdock, D.K.1    Kaliebe, J.2    Larrain, G.3
  • 24
    • 84922474004 scopus 로고    scopus 로고
    • 19 June 2014, date last accessed
    • The HARMONY Study. 2014. http://www.gilead.com/news/press-releases/2014/5/gilead-announces-results-from-phase-2-study-showing-reduction-in-atrial-fibrillationburden- with-the-investigational-combination-of-ranolazine-and-lowdose-droneda rone (19 June 2014, date last accessed
    • (2014) The Harmony Study


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.