A critical examination of studies on curcumin for depression

Journal of Clinical Psychiatry

Volumn 75, Issue 10, 2014, Pages e1110-e1112

  Andrade, Chittaranjan ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CURCUMIN; CURCUMINOID; FLUOXETINE; PIPERINE; PLACEBO; UNCLASSIFIED DRUG; NONSTEROID ANTIINFLAMMATORY AGENT;

ALTERNATIVE MEDICINE; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED CLINICAL TRIAL (TOPIC); DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG RESEARCH; DRUG SAFETY; DRUG TOLERABILITY; EVIDENCE BASED MEDICINE; HUMAN; MAJOR DEPRESSION; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT DURATION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; CLINICAL TRIAL (TOPIC); DEPRESSIVE DISORDER, MAJOR;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CLINICAL TRIALS AS TOPIC; CURCUMIN; DEPRESSIVE DISORDER, MAJOR; HUMANS;

EID: 84922392016     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.14f09489     Document Type: Article

References (18)

1. Andrade C, Aswath A, Chaturvedi SK, et al. A double-blind, placebocontrolled evaluation of the anxiolytic efficacy of an ethanolic extract of Withania somnifera. Indian J Psychiatry. 2000;42(3):295-301. PubMed
2. Andrade C, Chandra JS. Anti-amnestic properties of Brahmi and Mandookaparni in a rat model. Indian J Psychiatry. 2006;48(4):232-237. doi:10.4103/019-545.3154 PubMed
3. Stewart MG. Colostrinin: a naturally occurring compound derived from mammalian colostrum with efficacy in treatment of neurodegenerative diseases, including Alzheimer's. Expert Opin Pharmacother. 2008;9(14):2553-2559. doi:10.1517/1465656.9.14.253 PubMed
4. Choi YD, Park CW, Jang J, et al. Effects of Korean ginseng berry extract on sexual function in men with erectile dysfunction: a multicenter, placebocontrolled, double-blind clinical study. Int J Impot Res. 2013;25(2):45-50. doi:10.1038/ijir.2012.45 PubMed
5. Sarris J. St John's wort for the treatment of psychiatric disorders. Psychiatr Clin North Am. 2013;36(1):65-72. doi:10.1016/j.psc.2013.01.04 PubMed
6. Papakostas GI, Cassiello CF, Iovieno N. Folates and S-adenosylmethionine for major depressive disorder. Can J Psychiatry. 2012;57(7):406-413. PubMed
7. Gupta SC, Sung B, Kim JH, et al. Multitargeting by turmeric, the golden spice: from kitchen to clinic. Mol Nutr Food Res. 2013;57(9):1510-1528. doi:10.102/mnfr.2010741 PubMed
8. Lopresti AL, Hood SD, Drummond PD. Multiple antidepressant potential modes of action of curcumin: a review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects. J Psychopharmacol. 2012;26(12):1512-1524. doi:10.17/0269812458732 PubMed
9. Xu Y, Li S, Vernon MM, et al. Curcumin prevents corticosterone-induced neurotoxicity and abnormalities of neuroplasticity via 5-HT receptor pathway. J Neurochem. 2011;118(5):784-795. doi:10.1/j.1471-4159.201.07356.x PubMed
10. Dong S, Zeng Q, Mitchell ES, et al. Curcumin enhances neurogenesis and cognition in aged rats: implications for transcriptional interactions related to growth and synaptic plasticity. PLoS ONE. 2012;7(2):e31211. doi:10.1371/journal.pone.03121 PubMed
11. Liu D, Wang Z, Gao Z, et al. Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress. Behav Brain Res. 2014;271:116-121. doi:10.1016/j.br.2014.05.068 PubMed
12. Bergman J, Miodownik C, Bersudsky Y, et al. Curcumin as an add-on to antidepressive treatment: a randomized, double-blind, placebo-controlled, pilot clinical study. Clin Neuropharmacol. 2013;36(3):73-77. doi:10.1097/WNF.0b013e31828ef969 PubMed
13. Lopresti AL, Maes M, Maker GL, et al. Curcumin for the treatment of major depression: a randomised, double-blind, placebo controlled study. J Affect Disord. 2014;167:368-375. doi:10.1016/j.jad.2014.06.01 PubMed
14. Panahi Y, Badeli R, Karami GR, et al. Investigation of the efficacy of adjunctive therapy with bioavailability-boosted curcuminoids in major depressive disorder [published online ahead of print August 4, 2014]. Phytother Res. doi:10.102/ptr.521 PubMed
15. Sanmukhani J, Satodia V, Trivedi J, et al. Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. Phytother Res. 2014;28(4):579-585. doi:10.102/ptr.5025 PubMed
16. Cheng AL, Hsu CH, Lin JK, et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res. 2001;21(4B):2895-2900. PubMed
17. Andrade C. There's more to placebo-related improvement than the placebo effect alone. J Clin Psychiatry. 2012;73(10):1322-1325. doi:10.408/JCP.12f08124 PubMed
18. Kurita T, Makino Y. Novel curcumin oral delivery systems. Anticancer Res. 2013;33(7):2807-2821. PubMed